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  1. Previous studies have investigated the prognostic value of the systemic immune-inflammation index (SII) in nasopharyngeal carcinoma (NPC). However, the results have been inconsistent. Therefore, this study aim...

    Authors: Zesheng Zeng, Shengen Xu, Dingting Wang and Gang Qin
    Citation: Systematic Reviews 2022 11:247
  2. A good control of intraoperative bleeding is key for adequate anatomical visualization during endoscopic sinus surgery (ESS). The objective of this review was to assess the practice of hot intranasal saline ir...

    Authors: Darshini Nagarajah, Yee Cheng Kueh, Norhafiza Mat Lazim and Baharudin Abdullah
    Citation: Systematic Reviews 2022 11:246
  3. Worldwide, more immigrants experience vitamin D (vitD) deficiency than non-immigrants, which is attributed to ethnic variations, place or region of birth, skin pigmentation, clothing style, and resettlement-re...

    Authors: Said Yousef, Lamia Hayawi, Douglas Manuel, Ian Colman, Manny Papadimitropoulos, Alomgir Hossain, Moez AlIslam Faris and George A. Wells
    Citation: Systematic Reviews 2022 11:245
  4. Clinicians usually conduct diagnostic assessments in order to establish a diagnosis or to evaluate the effect of treatment. Two meta-analyses suggest that diagnostic assessment administered in collaboration wi...

    Authors: Oliver Rumle Hovmand, Ole Jakob Storebø, Nina Reinholt, Jasmin Rejaye Gryesten and Sidse M. Arnfred
    Citation: Systematic Reviews 2022 11:244
  5. The World Health Organization (WHO) has identified the need for evidence on third-line antiretroviral therapy (ART) for adults living with HIV/AIDS, given that some controversy remains as to the best combinati...

    Authors: Lucas Pitrez Mocellin, Patricia Klarmann Ziegelmann and Ricardo Kuchenbecker
    Citation: Systematic Reviews 2022 11:243
  6. Since the COVID-19 outbreak, preliminary research has shown that some risk-associated conditions increase death and severe complications of the disease, hypertension being one of them. Thus, numerous meta-anal...

    Authors: Yousof Khairy, Deniz Naghibi, Ahmad Moosavi, Mehran Sardareh and Saber Azami-Aghdash
    Citation: Systematic Reviews 2022 11:242
  7. Several studies have documented the production of wasteful research, defined as research of no scientific importance and/or not meeting societal needs. We argue that this redundancy in research may to a large ...

    Authors: Hans Lund, Karen A. Robinson, Ane Gjerland, Hanna Nykvist, Thea Marie Drachen, Robin Christensen, Carsten Bogh Juhl, Gro Jamtvedt, Monica Nortvedt, Merete Bjerrum, Matt Westmore, Jennifer Yost and Klara Brunnhuber
    Citation: Systematic Reviews 2022 11:241
  8. Klebsiella pneumoniae is a gram-negative rod belonging to the order Enterobacterales and having a wide distribution in the environment, including the human colon. Recently, the bacterium is one of the known prob...

    Authors: Tewodros Tesfa, Habtamu Mitiku, Mekuria Edae and Nega Assefa
    Citation: Systematic Reviews 2022 11:240
  9. Depression is common among patients with cancer and is associated with lower treatment participation, lower satisfaction with care, poorer quality of life, greater symptom burden and higher healthcare costs. V...

    Authors: Maria M. Pertl, Sergio Perez, Sonya Collier, Emer Guinan, Garret Monahan, Katie Verling, Emma Wallace, Aisling Walsh and Frank Doyle
    Citation: Systematic Reviews 2022 11:239
  10. Patients with chronic kidney disease (CKD) require a personalised strategy for cardiovascular risk management (CVRM) to reduce their high risk of cardiovascular morbidity and mortality. Despite their high risk...

    Authors: Julia M. T. Colombijn, Demy L. Idema, Kim van der Braak, Rene Spijker, Sabine C. A. Meijvis, Michiel L. Bots, Lotty Hooft, Marianne C. Verhaar and Robin W. M. Vernooij
    Citation: Systematic Reviews 2022 11:238
  11. Empirical evidence suggests data and insights from the clinical practice guidelines and clinical quality registries are not being fully utilised, leaving health service managers, clinicians and providers witho...

    Authors: Kathy Dempsey, Caleb Ferguson, Adam Walczak, Sandy Middleton, Christopher Levi and Rachael L. Morton
    Citation: Systematic Reviews 2022 11:237
  12. Due to the growing need to provide evidence syntheses under time constraints, researchers have begun focusing on the exploration of rapid review methods, which often employ single-reviewer literature screening...

    Authors: Lisa Affengruber, Andreea Dobrescu, Emma Persad, Irma Klerings, Gernot Wagner, Isolde Sommer and Gerald Gartlehner
    Citation: Systematic Reviews 2022 11:236
  13. Rare liver lesions and diseases have seldomly aroused major interest of researchers. For most guidelines, presumably similar clinical conditions are pooled without detailed investigations of singularities that...

    Authors: Juri Fuchs, Anastasia Murtha-Lemekhova, Jan Pfeiffenberger, Alexander Fichtner, Patrick Günther, Niels Halama, Philipp Mayer, Daniel Hornuss, Rosa Klotz, Pascal Probst and Katrin Hoffmann
    Citation: Systematic Reviews 2022 11:235
  14. During the past decade e-oral health technology has been used to address the oral health care challenges in rural and remote settings. This review systematically evaluated the literature on patient satisfactio...

    Authors: Elham Emami, Hermina Harnagea, Richa Shrivastava, Motahareh Ahmadi and Nicolas Giraudeau
    Citation: Systematic Reviews 2022 11:234
  15. Indigenous women in North America experience multiple inequities in terms of health and well-being when compared to non-Indigenous women and Indigenous men. In an effort to understand these health disparities,...

    Authors: Keira A. Loukes, Celeste Ferreira, Janice Cindy Gaudet and Tricia McGuire-Adams
    Citation: Systematic Reviews 2022 11:233
  16. This systematic overview was commissioned by England’s Department of Health and Social Care (DHSC) to assess the evidence on direct (previously ‘novel’) oral anticoagulants (OACs), compared with usual care, in...

    Authors: Claire Khouja, Ginny Brunton, Michelle Richardson, Gillian Stokes, Laurence Blanchard, Helen Burchett, Meena Khatwa, Ruth Walker, Kath Wright, Amanda Sowden and James Thomas
    Citation: Systematic Reviews 2022 11:232
  17. Fortification of foodstuffs with iodine, mainly through iodization of salt, which commenced in several African countries after 1995 is the main method for mitigating iodine deficiency in Africa. We assessed th...

    Authors: Charles Bitamazire Businge, Hannibal Tafadzwa Musarurwa, Benjamin Longo-Mbenza and Andre Pascal Kengne
    Citation: Systematic Reviews 2022 11:231
  18. To inform updated recommendations by the Canadian Task Force on Preventive Health Care on screening for prostate cancer in adults aged 18 years and older in primary care. This protocol outlines the planned sco...

    Authors: Alexandria Bennett, Andrew Beck, Nicole Shaver, Roland Grad, Allana LeBlanc, Heather Limburg, Casey Gray, Ahmed Abou-Setta, Scott Klarenbach, Navindra Persaud, Guylène Thériault, Brett D. Thombs, Keith J. Todd, Neil Bell, Philipp Dahm, Andrew Loblaw…
    Citation: Systematic Reviews 2022 11:230
  19. Cluster randomized trials (CRTs) are becoming an increasingly important design. However, authors of CRTs do not always adhere to requirements to explicitly identify the design as cluster randomized in titles a...

    Authors: Ahmed A. Al-Jaishi, Monica Taljaard, Melissa D. Al-Jaishi, Sheikh S. Abdullah, Lehana Thabane, P. J. Devereaux, Stephanie N. Dixon and Amit X. Garg
    Citation: Systematic Reviews 2022 11:229
  20. The early childhood development of millions of children in some low- and medium-income countries may be compromised by schistosomiasis infections contracted at the age of 5 years and below. Currently, there ar...

    Authors: Mhlengi Vella Ncube, Muhubiri Kabuyaya and Moses John Chimbari
    Citation: Systematic Reviews 2022 11:227
  21. Recently, several systematic reviews (SRs) and meta-analyses (MAs) of Tripterygium wilfordii polyglycoside (TWP) have reported significant benefits on diabetic kidney disease (DKD). However, the adoption of TWP f...

    Authors: Ying Wang, Mei Han, Yao-Tan Li, Zhen Wang and Jian-Ping Liu
    Citation: Systematic Reviews 2022 11:226
  22. To inform recommendations by the Canadian Task Force on Preventive Health Care on potentially inappropriate prescribing and over-the-counter (OTC) medication use among adults aged 65 years and older in primary...

    Authors: Andrew Beck, Navindra Persaud, Laure A. Tessier, Roland Grad, Michael R. Kidd, Scott Klarenbach, Christina Korownyk, Ainsley Moore, Brett D. Thombs, Dee Mangin, Rita K. McCracken, Emily G. McDonald, Caroline Sirois, Salmaan Kanji, Frank Molnar, Stuart G. Nicholls…
    Citation: Systematic Reviews 2022 11:225
  23. Iron supplementation and erythropoiesis-stimulating agent (ESA) administration represent the hallmark therapies in preoperative anemia treatment, as reflected in a set of evidence-based treatment recommendatio...

    Authors: Jorien Laermans, Hans Van Remoortel, Bert Avau, Geertruida Bekkering, Jørgen Georgsen, Paola Maria Manzini, Patrick Meybohm, Yves Ozier, Emmy De Buck, Veerle Compernolle and Philippe Vandekerckhove
    Citation: Systematic Reviews 2022 11:224
  24. The COVID-19 pandemic has disproportionately impacted homeless populations and service workers, especially within homeless shelter/hostel settings. To date, there have been few evidence syntheses examining out...

    Authors: Justine Levesque, Jordan Babando, Nathaniel Loranger, Shantel Johnson and David Pugh
    Citation: Systematic Reviews 2022 11:223
  25. As the life expectancy of people living with HIV increases with the advancements in antiretroviral treatment, the continuity of long-term therapy and health care for people living with HIV has gained more impo...

    Authors: Gwang Suk Kim, Youngin Kim, Min Kyung Park, Sang A Lee, Youngjin Lee and Mi-So Shim
    Citation: Systematic Reviews 2022 11:222
  26. There is limited evidence to evaluate the sustainability of evidence-based interventions (EBIs) for healthcare improvement. Through an integrative review, we aimed to identify approaches to evaluate the sustai...

    Authors: Rachel Flynn, Bonnie Stevens, Arjun Bains, Megan Kennedy and Shannon D. Scott
    Citation: Systematic Reviews 2022 11:221
  27. Suboptimal blood pressure control among people living with diabetes mellitus (DM) is one of the primary causes of cardiovascular complications and death in sub-Saharan Africa (SSA). However, there is a paucity...

    Authors: Yonas Akalu, Yigizie Yeshaw, Getayeneh Antehunegn Tesema, Sofonyas Abebaw Tiruneh, Achamyeleh Birhanu Teshale, Dessie Abebaw Angaw, Misganew Gebrie and Baye Dagnew
    Citation: Systematic Reviews 2022 11:220
  28. This scoping review aims to provide a broad overview of the research on the unassisted virtual physical exam performed over synchronous audio-video telemedicine to identify gaps in knowledge and guide future r...

    Authors: Peter Yao, Mahad Adam, Sunday Clark, Hanson Hsu, Michael Stern, Rahul Sharma, Keith Mages, Peter Greenwald and Neel Naik
    Citation: Systematic Reviews 2022 11:219
  29. Deep brain stimulation has been used since the 1980s for neurological disorders and the USA and Europe have now approved it for Parkinson’s disease, essential tremor, dystonia, and epilepsy. Previous reviews h...

    Authors: Johanne Juul Petersen, Sophie Juul, Caroline Kamp Jørgensen, Christian Gluud and Janus Christian Jakobsen
    Citation: Systematic Reviews 2022 11:218
  30. The development of risk prediction models for breast cancer lymphedema is increasing, but few studies focus on the quality of the model and its application. Therefore, this study aimed to systematically review...

    Authors: Qiu Lin, Tong Yang, Jin Yongmei and Ye Mao Die
    Citation: Systematic Reviews 2022 11:217
  31. Over the last decade, computational sciences have contributed immensely to characterization of phenotypes of airway diseases, but it is difficult to compare derived phenotypes across studies, perhaps as a resu...

    Authors: Muwada Bashir Awad Bashir, Rani Basna, Guo-Qiang Zhang, Helena Backman, Anne Lindberg, Linda Ekerljung, Malin Axelsson, Linnea Hedman, Lowie Vanfleteren, Bo Lundbäck, Eva Rönmark and Bright I. Nwaru
    Citation: Systematic Reviews 2022 11:216
  32. The increasing incidence of breast cancer necessitates the need to explore alternate screening strategies that circumvent the setbacks of conventional techniques especially among population that report earlier...

    Authors: Thejas Kathrikolly, Sreekumaran N. Nair, Aju Mathew, Prakash P. U. Saxena and Suma Nair
    Citation: Systematic Reviews 2022 11:215
  33. The provision of low-value care services in low back pain management is a problem of global scope. Inappropriate imaging, overmedication, and overused invasive therapies are prevalent in physician services. Ye...

    Authors: Lukas Kühn, Lara Lindert and Kyung-Eun Choi
    Citation: Systematic Reviews 2022 11:212
  34. Natural language processing could assist multiple tasks in systematic reviews to reduce workflow, including the extraction of PICO elements such as study populations, interventions, comparators and outcomes. T...

    Authors: Qianying Wang, Jing Liao, Mirella Lapata and Malcolm Macleod
    Citation: Systematic Reviews 2022 11:209
  35. Adolescent idiopathic scoliosis (AIS) is a three-dimensional rotational change in the normal shape of the spine which affects children aged 10 to 18 years. Both the condition and its management can have signif...

    Authors: Laura Hartley, Mattia Zappalà, Uzo Ehiogu, Nicola R. Heneghan and Adrian Gardner
    Citation: Systematic Reviews 2022 11:208
  36. Cardiovascular disease is the leading cause of death worldwide, with significantly worse mortality-related outcomes in ethnic minorities in developed countries. A systematic literature review and meta-analysis...

    Authors: Mubarak Patel, Salim Abatcha and Olalekan Uthman
    Citation: Systematic Reviews 2022 11:207
  37. A systematic review (SR) helps us make sense of a body of research while minimizing bias and is routinely conducted to evaluate intervention effects in a health technology assessment (HTA). In addition to the ...

    Authors: Joanne S. M. Kim, Michelle Pollock, David Kaunelis and Laura Weeks
    Citation: Systematic Reviews 2022 11:206
  38. Improving eHealth literacy (eHL) is one of the biggest challenges currently facing the global healthcare community. Indeed the use of digital services has the potential to engage patients in care as well as im...

    Authors: Carole Délétroz, Marina Canepa Allen, Maxime Sasseville, Alexandra Rouquette, Patrick Bodenmann and Marie-Pierre Gagnon
    Citation: Systematic Reviews 2022 11:205
  39. Isokinetic dynamometry (IKD) is considered as the gold standard method of eccentric hamstring strength measurement, but other devices are more portable, cost-effective, provide real-time data and are thus bett...

    Authors: Daniel Torpey, Eoghan Murray, Tom Hughes, Jamie Sergeant and Michael Callaghan
    Citation: Systematic Reviews 2022 11:204
  40. Long-term care facilities (LTCFs) have been severely affected by the COVID-19 pandemic with serious consequences for the residents. Some LTCFs performed better than others, experiencing lower case and death ra...

    Authors: Josiane Létourneau, Emilie Bélanger, Drissa Sia, Idrissa Beogo, Stephanie Robins, Katya Kruglova, Maripier Jubinville and Eric Nguemeleu Tchouaket
    Citation: Systematic Reviews 2022 11:203
  41. To provide a systematic overview of preclinical research regarding bone defect formation around different implant surfaces after ligature-induced peri-implantitis models in dogs. Two focused questions were for...

    Authors: A. Solderer, M. de Boer, D. B. Wiedemeier, M. Solderer, C. C. Liu and P. R. Schmidlin
    Citation: Systematic Reviews 2022 11:202
  42. Community engagement (CE) has been increasingly implemented across health interventions, including for maternal and newborn health (MNH). This may take various forms, from participatory women’s groups and comm...

    Authors: Sara Dada, Aoife De Brún, Esther Namwaba Banda, Sanghita Bhattacharya, Zaccheous Mutunga and Brynne Gilmore
    Citation: Systematic Reviews 2022 11:201
  43. The support provided by people with the same condition, including inflammatory bowel diseases (IBD), has the potential to improve a range of psychosocial outcomes by allowing people with the disease to receive...

    Authors: Ada Adriano, Dean M. Thompson, Christel McMullan, Malcolm Price, David Moore, Lesley Booth and Jonathan Mathers
    Citation: Systematic Reviews 2022 11:200
  44. The Calcaneus is the largest bone of the foot and the most frequent tarsal bone to be fractured. Overall, it causes round about 10 cases per 100,000 residents per year mainly in men. Especially displaced intra...

    Authors: Leah Wilmsen, Anne Neubert, Joachim Windolf, Andrea Icks, Bernd Richter and Simon Thelen
    Citation: Systematic Reviews 2022 11:199
  45. People with a mental health condition experience an elevated risk of chronic disease and greater prevalence of health and behaviours. Lifestyle interventions aim to reduce this risk by modifying health behavio...

    Authors: Tegan Bradley, Elizabeth Campbell, Julia Dray, Kate Bartlem, Paula Wye, Grace Hanly, Lauren Gibson, Caitlin Fehily, Jacqueline Bailey, Olivia Wynne, Kim Colyvas and Jenny Bowman
    Citation: Systematic Reviews 2022 11:198

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