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  1. Content type: Protocol

    Human immunodeficiency virus (HIV) infection and intimate partner violence (IPV) remain highly sensitive areas that have issues to do with stigmatization in many African countries. Despite the fact that there ...

    Authors: Felix Apiribu, Busisiwe Purity Ncama and Elizabeth Joseph-Shehu

    Citation: Systematic Reviews 2019 8:159

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  2. Content type: Protocol

    Trauma represents a major global health problem projected to increase in importance over the next decade. The majority of deaths occur in low- and middle-income countries (LMICs) where survival rates are lower...

    Authors: John Whitaker, Max Denning, Nollaig O’Donohoe, Dan Poenaru, Elena Guadagno, Andy Leather and Justine Davies

    Citation: Systematic Reviews 2019 8:157

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  3. Content type: Correction

    Following publication of the original article [1], the authors opted to revise Table 1. Below is the updated version of the table.

    Authors: Lisa Biernatzki, Silke Kuske, Jutta Genz, Michaela Ritschel, Astrid Stephan, Christina Bächle, Sigrid Droste, Sandra Grobosch, Nicole Ernstmann, Nadja Chernyak and Andrea Icks

    Citation: Systematic Reviews 2019 8:156

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    The original article was published in Systematic Reviews 2018 7:27

  4. Content type: Research

    The World Health Organization estimates that 29% of under-five mortality could be prevented with existing vaccines. However, non-consistent attendance for immunization appointments remains a global challenge t...

    Authors: Zeleke Abebaw Mekonnen, Kassahun Alemu Gelaye, Martin C. Were, Kassahun Dessie Gashu and Binyam Chakilu Tilahun

    Citation: Systematic Reviews 2019 8:154

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  5. Content type: Research

    Understanding the effects of gait speed on biomechanical variables is fundamental for a proper evaluation of alterations in gait, since pathological individuals tend to walk slower than healthy controls. There...

    Authors: Claudiane Arakaki Fukuchi, Reginaldo Kisho Fukuchi and Marcos Duarte

    Citation: Systematic Reviews 2019 8:153

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  6. Content type: Letter

    Much effort is made to ensure Cochrane reviews are based on reliably extracted data. There is a commitment to wide access to these data—for novel processing and/or reuse—but delivering this access is problematic.

    Authors: Lena Schmidt, Farhad Shokraneh, Kirsten Steinhausen and Clive E. Adams

    Citation: Systematic Reviews 2019 8:151

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  7. Content type: Protocol

    Phase III randomised controlled trials aim not just to increase the sum of human knowledge, but also to improve treatment, care or prevention for future patients through changing policy and practice. To achiev...

    Authors: Annabelle South, Julia Bailey, Mahesh K. B. Parmar and Claire L. Vale

    Citation: Systematic Reviews 2019 8:150

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  8. Content type: Protocol

    Asthma is a major worldwide public health problem affecting an estimated 334 million people with over 300,000 deaths annually. Twenty-two million disability-adjusted life years (DALYs) are lost annually due to...

    Authors: Pisirai Ndarukwa, Moses John Chimbari and Elopy N. Sibanda

    Citation: Systematic Reviews 2019 8:149

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  9. Content type: Protocol

    Even though data suggest that palliative care (PC) improves patient quality of life, caregiver burden, cost, and intensive care unit (ICU) length of stay, integration of PC in the ICU is far from being univers...

    Authors: Victoria Metaxa, Despina Anagnostou, Savvas Vlachos, Nishkantha Arulkumaran, Ingeborg van Dusseldorp, Sherihane Bensemmane, Rebecca Aslakson, Judy E. Davidson, Rik Gerritsen, Christiane Hartog and Randall Curtis

    Citation: Systematic Reviews 2019 8:148

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  10. Content type: Protocol

    Obesity is increasing globally. Chronic kidney disease (CKD) is strongly associated with obesity. Kidney function is commonly estimated with equations using creatinine (such as CKD-EPI equation) which is a pro...

    Authors: Sriram Sriperumbuduri, Robert Dent, Janine Malcolm, Swapnil Hiremath, Ran Klein, Christine A. White, Pierre Antoine Brown and Ayub Akbari

    Citation: Systematic Reviews 2019 8:147

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  11. Content type: Protocol

    Ocular toxoplasmosis (OT) is the most common cause of posterior uveitis, leading to visual impairment in a high proportion of patients. Antibiotics and corticosteroids lower the risk of permanent visual impair...

    Authors: John E. Feliciano-Alfonso, Andrés Vargas-Villanueva, María Alejandra Marín, Laura Triviño, Natalia Carvajal, Manuela Moreno, Tatiana Luna, Clara Lopez de Mesa, Juliana Muñoz-Ortiz and Alejandra de-la-Torre

    Citation: Systematic Reviews 2019 8:146

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  12. Content type: Research

    New software packages help to improve the efficiency of conducting a systematic review through automation of key steps in the systematic review. The aim of this study was to gather qualitative data on the usab...

    Authors: Gina Cleo, Anna Mae Scott, Farhana Islam, Blair Julien and Elaine Beller

    Citation: Systematic Reviews 2019 8:145

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  13. Content type: Protocol

    There is some evidence that simply measuring physical activity alone can increase self-reported physical activity behaviour. Objective measures of physical activity in intervention studies have increased subst...

    Authors: Nicole Freene, Rachel Davey and Steven M. McPhail

    Citation: Systematic Reviews 2019 8:144

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  14. Content type: Protocol

    Tendinopathies are specific degenerative conditions of the tendon characterized by pain and disability. The most common tendinopathies of the lower limbs are patellar, Achilles, gluteal, and proximal tendinopa...

    Authors: Yuri Rafael dos Santos Franco, Gisela Cristiane Miyamoto, Katherinne Ferro Moura Franco, Rodrigo Ribeiro de Oliveira and Cristina Maria Nunes Cabral

    Citation: Systematic Reviews 2019 8:142

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  15. Content type: Protocol

    Autism spectrum disorder (ASD) is a complex developmental disorder characterised by impaired social interaction and communication, and restrictive and repetitive behaviour. Previous systematic reviews have tra...

    Authors: Ferrán Catalá-López, Manuel Ridao, Isabel Hurtado, Amparo Núñez-Beltrán, Ricard Gènova-Maleras, Adolfo Alonso-Arroyo, Aurelio Tobías, Rafael Aleixandre-Benavent, Miguel A. Catalá and Rafael Tabarés-Seisdedos

    Citation: Systematic Reviews 2019 8:141

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  16. Content type: Protocol

    Acceptance and commitment therapy (ACT) can be effective in treating chronic pain. Despite evidence supporting the effectiveness of ACT, uncertainties remain regarding which subgroups in the chronic pain popul...

    Authors: Jiaxi Lin, Whitney Scott, Lewis Carpenter, Sam Norton, Matthias Domhardt, Harald Baumeister and Lance M. McCracken

    Citation: Systematic Reviews 2019 8:140

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  17. Content type: Protocol

    Immuno-oncology, and in particular, check-point inhibitors (CPIs), have led to a paradigm shift in the field of cancer care. The cost of new drug development is high, and many novel agents in oncology are sign...

    Authors: Ying Wang, Pierre Camateros, Denise Smith, David Dawe and Peter Ellis

    Citation: Systematic Reviews 2019 8:139

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  18. Content type: Protocol

    North America is in the midst of an unabated opioid overdose epidemic due to the increasing non-medical use of fentanyl and ultra-potent opioids. Naloxone is an effective antidote to opioid toxicity, yet its o...

    Authors: Lindsay Victoria Shaw, Jessica Moe, Roy Purssell, Jane A. Buxton, Jesse Godwin, Mary M. Doyle-Waters, Penelope M. A. Brasher, Jeffrey P. Hau, Jason Curran and Corinne M. Hohl

    Citation: Systematic Reviews 2019 8:138

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  19. Content type: Protocol

    Shared decision-making is an approach to making treatment-based decisions that rely on the patient encounter and clear discussions between the patient and the healthcare provider. Patients with arthritis of th...

    Authors: Daniel L. Riddle, Trisha Sando, Talicia Tarver, James Slover, Robert A. Perera, Rafael Sierra, Juan P. Brito and Victor M. Montori

    Citation: Systematic Reviews 2019 8:137

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  20. Content type: Protocol

    Despite the increased utilization of clinical pathways (CPWs) as a strategy to improve patient and system outcomes in hospitals, there remain ongoing challenges with their conceptualization, implementation, an...

    Authors: Adegboyega K. Lawal, Gary Groot, Donna Goodridge, Shannon Scott and Leigh Kinsman

    Citation: Systematic Reviews 2019 8:136

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  21. Content type: Protocol

    Telemedicine use is increasing in many specialties, but its impact on clinical outcomes in infectious diseases has not been systematically studied and reviewed. The proposed systematic review will evaluate the...

    Authors: Jason P. Burnham, Stephanie A. Fritz, Lauren H. Yaeger and Graham A. Colditz

    Citation: Systematic Reviews 2019 8:135

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  22. Content type: Research

    Living alone has become more common in today’s societies. Despite the high number of the population living alone, research directed towards the mental wellbeing issues related to living alone has been limited....

    Authors: Nina Tamminen, Tarja Kettunen, Tuija Martelin, Jaakko Reinikainen and Pia Solin

    Citation: Systematic Reviews 2019 8:134

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  23. Content type: Research

    Cervical cancer is a major public health issue in the world, especially in developing countries. It can be prevented through vaccination against HPV (primary prevention) and through screening and treatment of ...

    Authors: Alex Baleka Mutombo, Cindy Simoens, Rahma Tozin, Johannes Bogers, Jean-Pierre Van Geertruyden and Yves Jacquemyn

    Citation: Systematic Reviews 2019 8:132

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  24. Content type: Protocol

    Upon surviving the first year post-lung transplantation, recipients can expect a median survival of 8 years. Within the first year, graft failure and multi-organ failure (possibly secondary to graft failure) a...

    Authors: Farid Foroutan, Gordon Guyatt, Erik Friesen, Luis Enrique Colunga Lozano, Aman Sidhu and Maureen Meade

    Citation: Systematic Reviews 2019 8:131

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  25. Content type: Research

    Consuming whey protein supplements, along with physiotherapy and psychotherapy, have been recognised in sports performance. Whey protein supplements (WPS) is one of the commonly used supplements as ergogenic a...

    Authors: Fui-Ching Lam, Tahir Mehmood Khan, Hani Faidah, Abdul Haseeb and Amer Hayat Khan

    Citation: Systematic Reviews 2019 8:130

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  26. Content type: Protocol

    Estimation of the dietary requirements for vitamin D is crucial from a public health perspective in providing a framework for the prevention of vitamin D deficiency. It has been shown that pooling individual p...

    Authors: Kevin D. Cashman and Christian Ritz

    Citation: Systematic Reviews 2019 8:128

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  27. Content type: Protocol

    Physical attractiveness or unattractiveness wields a tremendous impact on the social and psychological components of life. Many individuals with facial deformities are treated more negatively than normal indiv...

    Authors: Mikaela I. Poling and Craig R. Dufresne

    Citation: Systematic Reviews 2019 8:127

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  28. Content type: Protocol

    Sensorineural hearing loss (SNHL) is the most common form of hearing impairment and is characterized by a loss of receptor hair cells and/or spiral ganglion neurons. Regenerative stem cell therapy could potent...

    Authors: Kevin T. Chorath, Matthew J. Willis, Nicolas Morton-Gonzaba, Walter J. Humann and Alvaro Moreira

    Citation: Systematic Reviews 2019 8:126

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  29. Content type: Protocol

    There is great interest in the possibility that ‘stage of illness’ moderates treatment outcomes in bipolar disorder (BD). Much remains unknown about the construct of stage of illness, but there is evidence tha...

    Authors: Hailey Tremain, Kathryn Fletcher, Jan Scott, Carla McEnery, Michael Berk and Greg Murray

    Citation: Systematic Reviews 2019 8:125

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  30. Content type: Protocol

    Many people who have common mental disorders, such as depression and anxiety, also have some psychotic experiences. These experiences are associated with higher clinical complexity, poor treatment response, an...

    Authors: Emma Soneson, Debra Russo, Clare Knight, Louise Lafortune, Margaret Heslin, Jan Stochl, Alex Georgiadis, Julieta Galante, Robbie Duschinsky, Nick Grey, Leticia Gonzalez-Blanco, Juliet Couche, Michelle Griffiths, Hannah Murray, Nesta Reeve, Joanne Hodgekins…

    Citation: Systematic Reviews 2019 8:124

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  31. Content type: Protocol

    Improving the quality of primary healthcare services is one of the global health priorities. Literature shows that the incompetency of healthcare providers has the potential to negatively affect the quality of...

    Authors: Nkosinothando Chamane, Desmond Kuupiel and Tivani Phosa Mashamba-Thompson

    Citation: Systematic Reviews 2019 8:123

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  32. Content type: Protocol

    Better characterisation of the epidemiological data on respiratory viral infections among people with acute respiratory tract infection (ARTI) can help to implement efficient strategies to curb the burden of A...

    Authors: Sebastien Kenmoe, Jean Joel Bigna, Abdou Fatawou Modiyinji, Fredy Brice N. Simo and Richard Njouom

    Citation: Systematic Reviews 2019 8:122

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  33. Content type: Research

    Shared decision making (SDM) is a patient-centered approach in which clinicians and patients work together to find and choose the best course of action for each patient’s particular situation. Six SDM key elem...

    Authors: Thomas H. Wieringa, Rene Rodriguez-Gutierrez, Gabriela Spencer-Bonilla, Maartje de Wit, Oscar J. Ponce, Manuel F. Sanchez-Herrera, Nataly R. Espinoza, Yaara Zisman-Ilani, Marleen Kunneman, Linda J. Schoonmade, Victor M. Montori and Frank J. Snoek

    Citation: Systematic Reviews 2019 8:121

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  34. Content type: Protocol

    Hepatitis E virus (HEV) is one of the major causes of acute hepatitis in humans worldwide with a case-fatality rate of 1–4% in the general population that might reach 30% in pregnant women. In the past decade ...

    Authors: Abdou Fatawou Modiyinji, Jean Joel Bigna, Fredy Brice N. Simo, Moise Nola, Marie S. Ndangang, Sebastien Kenmoe and Richard Njouom

    Citation: Systematic Reviews 2019 8:120

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  35. Content type: Protocol

    Experiential peers are increasingly involved in the development and delivery of interventions for individuals who are engaged in delinquent behavior. Experiential peer support, which is the provision of suppor...

    Authors: Margriet Lenkens, Frank J. van Lenthe, Loïs Schenk, Tessa Magnée, Miranda Sentse, Sabine Severiens, Godfried Engbersen and Gera E. Nagelhout

    Citation: Systematic Reviews 2019 8:119

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  36. Content type: Protocol

    Behavioral and psychological symptoms of dementia (BPSD) are present in a majority of patients with dementia contributing to increased morbidity, health care costs, and caregiver burden. While there are no Uni...

    Authors: Sophiya Benjamin, John W. Williams Jr, Cecilia Cotton, Jennifer Tung, Howard An, Stephanie Sanger and Joanne Man-Wai Ho

    Citation: Systematic Reviews 2019 8:118

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  37. Content type: Protocol

    Due to a growing reliance on mobile phone technology and decreasing mobile phone costs, the use of mobile phones is on the rise, especially among the youth population. Young people are responsive and enthusias...

    Authors: Anam Feroz, Farina Abrejo, Sumera Aziz Ali, Rozina Nuruddin and Sarah Saleem

    Citation: Systematic Reviews 2019 8:117

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  38. Content type: Protocol

    Polycystic ovary syndrome (PCOS) is the most common endocrinopathy, affecting 4–12% of reproductive-aged women. Women with PCOS often exhibit many metabolic abnormalities that are associated with an increased ...

    Authors: Amie Woodward, Markos Klonizakis, Ian Lahart, Anouska Carter, Caroline Dalton, Mostafa Metwally and David Broom

    Citation: Systematic Reviews 2019 8:116

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  39. Content type: Protocol

    The lifetime risk of suicide in patients with substance use disorder is five to ten times the risk in the general population. Critically, up to 19% of patients continue to think about and attempt suicide even ...

    Authors: S. Espinet, T. Corrin, D. Baliunas, L. Quilty, L. Zawertailo, S. J. Rizvi, W. deRuiter, S. Bonato, V. De Luca, S. Kennedy and P. Selby

    Citation: Systematic Reviews 2019 8:115

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  40. Content type: Protocol

    Despite a considerable amount of epidemiological research for identification of risk factors involved in the development of colorectal cancer, the current understanding of the etiology of this disease remains ...

    Authors: Amal Idrissi Janati, Igor Karp, Hisham Sabri and Elham Emami

    Citation: Systematic Reviews 2019 8:114

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  41. Content type: Protocol

    Recent studies have observed low levels of physical activity in children and adolescents worldwide. Physical activity interventions are increasingly carried out to counteract this development. The school envir...

    Authors: Yolanda Demetriou, Anne K. Reimers, Marianna Alesi, Lidia Scifo, Carla Chicau Borrego, Diogo Monteiro and Anne Kelso

    Citation: Systematic Reviews 2019 8:113

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  42. Content type: Protocol

    Despite policies for universal HIV testing and treatment (UTT) regardless of CD4 count, there are still 1.8 million new HIV infections and 1 million AIDS-related deaths annually. The UNAIDS 90-90-90 goals targ...

    Authors: Dylan Green, Brenda Kharono, Diana M. Tordoff, Adam Akullian, Anna Bershteyn, Michelle Morrison, Geoff Garnett, Ann Duerr and Paul Drain

    Citation: Systematic Reviews 2019 8:110

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  43. Content type: Protocol

    Acute myeloid leukaemia is the most common type of acute leukaemia in the world. Thus, the study of genetic alterations, such as single-nucleotide polymorphisms (SNPs), has contributed to a better understandin...

    Authors: Taynah Cascaes Puty, Jonathan Souza Sarraf, Tabata Cristina Do Carmo Almeida, Valter Cordeiro Barbosa Filho, Luis Eduardo Werneck de Carvalho, Fernando Luiz Affonso Fonseca and Fernando Adami

    Citation: Systematic Reviews 2019 8:109

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