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  1. Content type: Protocol

    Liver cirrhosis represents a substantial global burden in terms of morbidity and mortality. Observational studies have reported an increased risk of death with low circulating 25-hydroxyvitamin D concentration...

    Authors: Désirée Völker, Frank Grünhage, Stefan Wagenpfeil, Frank Lammert and Caroline S. Stokes

    Citation: Systematic Reviews 2019 8:73

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  2. Content type: Protocol

    Suicide is an emergency psychiatric problem that needs an urgent intervention. Ethiopia, as a nation, has been experiencing high burden of suicide. Cultural taboo, stigma, and criticism associated with suicida...

    Authors: Berhanu Boru Bifftu, Berihun Assefa Dachew, Bewket Tadesse Tiruneh and Yonas Deressa Guracho

    Citation: Systematic Reviews 2019 8:72

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  3. Content type: Protocol

    Depression is common in patients with coronary artery disease (CAD) and is associated with poorer outcomes and higher costs. Several randomised controlled trials (RCTs) targeting depression, of various modalit...

    Authors: Frank Doyle, Kenneth Freedland, Robert Carney, Peter de Jonge, Chris Dickens, Susanne Pedersen, Jan Sorensen and Martin Dempster

    Citation: Systematic Reviews 2019 8:71

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  4. Content type: Protocol

    Approximately 50% of all youth-onset type 2 diabetes mellitus (T2DM) in Canada occurs in Indigenous children. In adults, cardiovascular disease is one of the leading causes of mortality in First Nations commun...

    Authors: Rebecca Crawford, E. Danielle Sims, Kuan-Wen Wang, Michael Youssef, Ajantha Nadarajah, Angelica Rivas, Laura Banfield, Lehana Thabane and M. Constantine Samaan

    Citation: Systematic Reviews 2019 8:69

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  5. Content type: Protocol

    The HIV/AIDS pandemic has struck regions, countries, and populations in different ways. With the introduction of antiretroviral drugs, people living with HIV (PLHIV) have a much better prognosis, even though t...

    Authors: Trust Chibawara, Lawrence Mbuagbaw, Marcel Kitenge and Peter Nyasulu

    Citation: Systematic Reviews 2019 8:68

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  6. Content type: Commentary

    Peer-led support groups play an important role in supporting people with chronic diseases. They may be particularly important for people with rare diseases who typically do not have access to professional supp...

    Authors: Kimberly A. Turner, Danielle B. Rice, Andrea Carboni-Jiménez, Jill Boruff and Brett D. Thombs

    Citation: Systematic Reviews 2019 8:67

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  7. Content type: Research

    As with food-taxation strategies, such interventions as discounted healthy menus, point-of-purchase advertisements, and sugar-free beverages for employees at worksites could help prevent obesity. This study as...

    Authors: Kimi Sawada, Koji Wada, Sadequa Shahrook, Erika Ota, Yukari Takemi and Rintaro Mori

    Citation: Systematic Reviews 2019 8:66

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  8. Content type: Protocol

    Low levels of physical activity (PA) and high levels of sedentary behaviour (SB) have been observed in young people. Both behaviours are detrimental for health with patterns tending to continue into adulthood....

    Authors: Yolanda Demetriou, Catherina Vondung, Jens Bucksch, Annegret Schlund, Carolin Schulze, Guido Knapp, Stephanie E. Coen, Lorri Puil, Susan P. Phillips and Anne K. Reimers

    Citation: Systematic Reviews 2019 8:65

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  9. Content type: Research

    Youths living with HIV/AIDS (YLWHA) experience innumerable challenges within schools and the larger community. Nonetheless, these environments are potential sources of support for such youths. This review prov...

    Authors: Emmanuel Kimera, Sofie Vindevogel, Jessica De Maeyer, Didier Reynaert, Anne-Mie Engelen, Fred Nuwaha, John Rubaihayo and Johan Bilsen

    Citation: Systematic Reviews 2019 8:64

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  10. Content type: Systematic review update

    According to the 2015 World Health Organization report, globally, an estimated 10.7 million mothers died from 1990 to 2015 due to obstetric complications. This report showed that almost all global maternal dea...

    Authors: Ayele Geleto, Catherine Chojenta, Abdulbasit Musa and Deborah Loxton

    Citation: Systematic Reviews 2019 8:63

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  11. Content type: Protocol

    Depression is the leading cause of disability worldwide and is known to be associated with insulin resistance (IR). Insulin resistance worsens the symptoms of depression and reduces the effectiveness of antide...

    Authors: Olaitan J. Jeremiah, Gráinne Cousins, Finbarr P. Leacy, Brian P. Kirby and Benedict K. Ryan

    Citation: Systematic Reviews 2019 8:62

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  12. Content type: Protocol

    Periodontal diseases are responsible for a vast burden of disease globally and are associated with other severe illnesses such as cardiovascular diseases or diabetes. Tests for early diagnosis of periodontal d...

    Authors: Birgit Teufer, Isolde Sommer, Barbara Nussbaumer-Streit, Viktoria Titscher, Corinna Bruckmann, Irma Klerings and Gerald Gartlehner

    Citation: Systematic Reviews 2019 8:61

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  13. Content type: Protocol

    The ever-increasing global hepatitis C infection is fueling the burden of diabetes mellitus, which exaggerates various complications and may be a cause of death for millions. Several studies have reported that...

    Authors: Sintayehu Ambachew, Setegn Eshetie, Demeke Geremew, Aklilu Endalamaw and Mulugeta Melku

    Citation: Systematic Reviews 2019 8:60

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  14. Content type: Research

    Gender-based violence is a public health issue. The prevalence of gender-based violence is high in Sub-Saharan Africa. Therefore, this study aims to produce an overall summary estimate on the prevalence of gen...

    Authors: Addisu Shunu Beyene, Catherine Chojenta, Hirbo Shore Roba, Alemu Sufa Melka and Deborah Loxton

    Citation: Systematic Reviews 2019 8:59

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  15. Content type: Protocol

    The widespread implementation of acellular dermal matrix (ADM) has broadened the reconstructive repertoire for alloplastic breast reconstruction. ADM’s role in the context of postoperative radiation therapy re...

    Authors: Amy M. Chung, Michael J. Stein, Ammara Ghumman and Jing Zhang

    Citation: Systematic Reviews 2019 8:58

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  16. Content type: Commentary

    The third meeting of the International Collaboration for Automation of Systematic Reviews (ICASR) was held 17–18 October 2017 in London, England. ICASR is an interdisciplinary group whose goal is to maximize t...

    Authors: Annette M. O’Connor, Guy Tsafnat, Stephen B. Gilbert, Kristina A. Thayer, Ian Shemilt, James Thomas, Paul Glasziou and Mary S. Wolfe

    Citation: Systematic Reviews 2019 8:57

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  17. Content type: Research

    A number of studies have explored factors associated with resident length of stay in care homes; however the findings of these studies have not been synthesized. The aim of this paper is to provide a systemati...

    Authors: Danni Collingridge Moore, Thomas J. Keegan, Lesley Dunleavy and Katherine Froggatt

    Citation: Systematic Reviews 2019 8:56

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  18. Content type: Protocol

    At least 2.6 million adults and children receive dialysis treatment for end-stage kidney disease (ESKD) worldwide. The large majority of these receive hemodialysis (HD), while the remaining receive peritoneal ...

    Authors: Mark R. Marshall, Chun-Yuan Hsiao, Philip K. Li, Masaaki Nakayama, S. Rabindranath, Rachael C. Walker, Xueqing Yu and Suetonia C. Palmer

    Citation: Systematic Reviews 2019 8:55

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  19. Content type: Protocol

    Electronic health records (EHRs) are increasing in popularity across national and international healthcare systems. Despite their augmented availability and use, the quality of electronic health records is pro...

    Authors: Lucia Otero Varela, Natalie Wiebe, Daniel J. Niven, Paul E. Ronksley, Nicolas Iragorri, Helen Lee Robertson and Hude Quan

    Citation: Systematic Reviews 2019 8:54

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  20. Content type: Protocol

    The use of physical activity monitors (PAMs) in the adult population is increasing rapidly and previous systematic reviews are outdated. The objective of this systematic review and meta-analysis is to estimate...

    Authors: Rasmus Tolstrup Larsen, Vibeke Wagner, Camilla Keller, Carsten Bogh Juhl, Henning Langberg and Jan Christensen

    Citation: Systematic Reviews 2019 8:53

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  21. Content type: Protocol

    Evidence from studies on prostate cancer progression have identified vitamin D to be a potentially important nutrient. However, the World Cancer Research Fund and American Institute for Cancer Research have re...

    Authors: Luke A. Robles, Karen Dawe, Richard M. Martin, Julian P. T. Higgins and Sarah J. Lewis

    Citation: Systematic Reviews 2019 8:52

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  22. Content type: Research

    Typically, management of PCOS focuses on lifestyle changes (exercise and diet), aiming to alleviate symptoms, and lower the associated risk of type 2 diabetes and cardiovascular disease. Our objective was to a...

    Authors: Chris Kite, Ian M. Lahart, Islam Afzal, David R. Broom, Harpal Randeva, Ioannis Kyrou and James E. Brown

    Citation: Systematic Reviews 2019 8:51

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  23. Content type: Protocol

    There is increasing recognition in Canada and globally that a substantial proportion of health care delivered is inappropriate as evidenced by (1) harmful and/or ineffective practices being overused, (2) effec...

    Authors: Janet E. Squires, Ian D. Graham, Doris Grinspun, John Lavis, France Légaré, Robert Bell, Stephen Bornstein, Susan E. Brien, Mark Dobrow, Megan Greenough, Carole A. Estabrooks, Michael Hillmer, Tanya Horsley, Alan Katz, Christina Krause, Wendy Levinson…

    Citation: Systematic Reviews 2019 8:50

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  24. Content type: Protocol

    Attention deficit hyperactivity disorder (ADHD) is a childhood-onset disorder characterized by a persistent pattern of symptoms of developmentally inappropriate and impaired inattention and/or hyperactivity/im...

    Authors: Ferrán Catalá-López, Manuel Ridao, Amparo Núñez-Beltrán, Ricard Gènova-Maleras, Adolfo Alonso-Arroyo, Rafael Aleixandre-Benavent, Miguel A. Catalá and Rafael Tabarés-Seisdedos

    Citation: Systematic Reviews 2019 8:49

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  25. Content type: Protocol

    The health impacts of loneliness and social isolation among older adults are widely acknowledged. Despite this, there is no consensus on the possible causal nature of this relationship, which could undermine e...

    Authors: Martin Malcolm, Helen Frost and Julie Cowie

    Citation: Systematic Reviews 2019 8:48

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  26. Content type: Protocol

    Mental distress is an important public health problem and becoming a common health problem among university students. This systematic review and meta-analysis will provide the pooled prevalence of mental distr...

    Authors: Berihun Assefa Dachew, Berhanu Boru Bifftu, Bewket Tadesse Tiruneh, Degefaye Zelalem Anlay, Meseret Adugna Wassie and Kim Betts

    Citation: Systematic Reviews 2019 8:47

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  27. Content type: Letter

    Research turnover in the HIV field is rapid, and as a result, maintaining high-quality, up-to-date, and relevant systematic reviews is a challenge. One approach is to frequently update published reviews.

    Authors: Ingrid Eshun-Wilson, Shahista Jaffer, Rhodine Smith, Samuel Johnson, Paul Hine, Alberto Mateo, Anne-Marie Stephani and Paul Garner

    Citation: Systematic Reviews 2019 8:46

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  28. Content type: Protocol

    Angioplasty is a fundamental treatment for atherosclerotic disease in the cardiac, cerebrovascular, and peripheral vascular beds. However, the optimal duration of balloon inflation has not been identified. Our...

    Authors: Mark Rockley, Prasad Jetty, George Wells, Kathleen Rockley and Dean Fergusson

    Citation: Systematic Reviews 2019 8:45

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  29. Content type: Research

    Transcatheter aortic valve replacement (TAVI) is an alternative treatment for patients with symptomatic severe aortic stenosis ineligible for surgical aortic valve replacement (SAVR) or at increased perioperat...

    Authors: Gernot Wagner, Sabine Steiner, Gerald Gartlehner, Henrike Arfsten, Brigitte Wildner, Harald Mayr and Deddo Moertl

    Citation: Systematic Reviews 2019 8:44

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  30. Content type: Systematic review update

    Regular/frequent dental visits, at least annually, can aid in reducing the public health burden of head and neck cancers (HNCs) by facilitating earlier detection of the disease. The aim of this study was to co...

    Authors: Bhawna Gupta, Narinder Kumar and Newell W. Johnson

    Citation: Systematic Reviews 2019 8:43

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  31. Content type: Research

    In 2016, WHO reported a death rate of 303,000 newborns before 4 weeks of age due to congenital anomalies. Those that survive congenital anomalies may have long-term disabilities which may have significant impa...

    Authors: Abiola Omodan, Pamela Pillay, Lelika Lazarus, Anil Madaree and Kapil Satyapal

    Citation: Systematic Reviews 2019 8:42

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  32. Content type: Protocol

    Obesity is a global epidemic with profound consequences for individuals and societies. Physical exercise is important to weight reduction and weight loss maintenance. However, results on what the most effectiv...

    Authors: Lene Aasdahl, Vegard Moe Iversen, Eva Skovlund, Dagfinn Aune and Marius Steiro Fimland

    Citation: Systematic Reviews 2019 8:41

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  33. Content type: Protocol

    Heart failure (HF) is a complex chronic condition, leading to frequent hospitalization, decreased quality of life, and increased mortality. Current guidelines recommend that multidisciplinary care be provided ...

    Authors: Morgan Slater, Joanna Bielecki, Ana Carolina Alba, Lusine Abrahamyan, George Tomlinson, Susanna Mak, Jane MacIver, Shelley Zieroth, Douglas Lee, William Wong, Murray Krahn, Heather Ross and Valeria E. Rac

    Citation: Systematic Reviews 2019 8:40

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  34. Content type: Protocol

    Coronary artery disease and heart failure are both highly prevalent diseases with a global prevalence of 93 million and 40 million. These patients are at increased risk of morbidity and mortality. The manageme...

    Authors: M. Maagaard, E. E. Nielsen, C. Gluud and J. C. Jakobsen

    Citation: Systematic Reviews 2019 8:39

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  35. Content type: Protocol

    The use of audit and feedback (A&F) interventions in health care has been demonstrated to generally be effective on medical teams. However, literature suggests that the response of nurses to this type of inter...

    Authors: Émilie Dufour, Arnaud Duhoux and Jolianne Bolduc

    Citation: Systematic Reviews 2019 8:38

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  36. Content type: Protocol

    Cancer survivors face a myriad of biopsychosocial consequences due to cancer and treatment that may be potentially mitigated through enabling their self-management skills and behaviors for managing illness. Un...

    Authors: Doris Howell, Alison Richardson, Carl May, Lynn Calman, Rouhi Fazelzad, Saeed Moradian and Claire Foster

    Citation: Systematic Reviews 2019 8:37

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  37. Content type: Protocol

    Previous meta-analyses have found several advantages of icodextrin compared with glucose in the application of peritoneal dialysis (PD), such as an improvement of peritoneal ultrafiltration during the long dwe...

    Authors: Monika Becker, Stefanie Bühn, Jessica Breuing, Catherine A. Firanek, Simone Hess, Hisanori Nariai, Mark R. Marshall, James A. Sloand, Qiang Yao, Käthe Goossen and Dawid Pieper

    Citation: Systematic Reviews 2019 8:35

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  38. Content type: Protocol

    Physical resilience is the ability to optimize or recover motor function in the face of disease, injury, or aging-related decline. Greater knowledge of how some individuals regain or maintain function despite ...

    Authors: Sue Peters, Theodore D. Cosco, Dawn C. Mackey, Gurkaran S. Sarohia, Jeffrey Leong and Andrew Wister

    Citation: Systematic Reviews 2019 8:34

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  39. Content type: Protocol

    Pain in children and adolescents with cancer has been identified as an area where many healthcare professionals seek guidance. This protocol details a systematic review whose aim is to explore current knowledg...

    Authors: Erik A. H. Loeffen, Jennifer N. Stinson, Kathryn A. Birnie, Monique van Dijk, Ketan Kulkarni, Mienke Rijsdijk, Anna Font-Gonzalez, L. Lee Dupuis, Elvira C. van Dalen, Renée L. Mulder, Fiona Campbell, Wim J. E. Tissing, Marianne D. van de Wetering and Faith Gibson

    Citation: Systematic Reviews 2019 8:33

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  40. Content type: Protocol

    Emergence coughing and bucking, secondary to endotracheal tube stimulation of the tracheal mucosa, frequently occurs after the general anesthetic recedes. Besides general unpleasantness, coughing has important...

    Authors: Alan Tung, Nicholas A. Fergusson, Nicole Ng, Vivien Hu, Colin Dormuth and Donald G. E. Griesdale

    Citation: Systematic Reviews 2019 8:32

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  41. Content type: Correction

    Following publication of the original article [1], the authors reported an error in Table 1 as the wrong table was used.

    Authors: Jessica Breuing, Dawid Pieper, Annika Lena Neuhaus, Simone Heß, Lena Lütkemeier, Fabiola Haas, Mark Spiller and Christine Graf

    Citation: Systematic Reviews 2019 8:31

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    The original article was published in Systematic Reviews 2018 7:245

  42. Content type: Protocol

    Uveitis describes a group of inflammatory conditions affecting the eye. The ability to monitor inflammatory changes in anterior uveitis is crucial in clinical practice for making treatment decisions and in cli...

    Authors: Xiaoxuan Liu, Ameenat L. Solebo, Pearse A. Keane, David J. Moore and Alastair K. Denniston

    Citation: Systematic Reviews 2019 8:30

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  43. Content type: Research

    Overviews of reviews of healthcare interventions (overviews) integrate information from multiple systematic reviews (SRs) to provide a single synthesis of relevant evidence for decision-making. Overviews may i...

    Authors: Michelle Pollock, Ricardo M. Fernandes, Amanda S. Newton, Shannon D. Scott and Lisa Hartling

    Citation: Systematic Reviews 2019 8:29

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  44. Content type: Protocol

    Tobacco smoking is the leading cause of cancer, preventable death, and disability. Smoking cessation can increase life expectancy by nearly a decade if achieved in the third or fourth decades of life. Various ...

    Authors: Mona Hersi, Gregory Traversy, Brett D. Thombs, Andrew Beck, Becky Skidmore, Stéphane Groulx, Eddy Lang, Donna L. Reynolds, Brenda Wilson, Steven L. Bernstein, Peter Selby, Stephanie Johnson-Obaseki, Douglas Manuel, Smita Pakhale, Justin Presseau, Susan Courage…

    Citation: Systematic Reviews 2019 8:28

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  45. Content type: Protocol

    In 2018, the World Health Organization reported that depression is the most common cause of disability worldwide, with over 300 million people currently living with depression. Depression affects an individual...

    Authors: Candyce Hamel, Eddy Lang, Kate Morissette, Andrew Beck, Adrienne Stevens, Becky Skidmore, Heather Colquhoun, John LeBlanc, Ainsley Moore, John J. Riva, Brett D. Thombs, Ian Colman, Sophie Grigoriadis, Stuart Gordon Nicholls, Beth K. Potter, Kerri Ritchie…

    Citation: Systematic Reviews 2019 8:27

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  46. Content type: Protocol

    Socialization is an important part of the healthy aging process, but natural changes in the lifestyle and health of older people increased risk of loneliness. However, loneliness is not well defined and might ...

    Authors: Razieh Bandari, Hamid Reza Khankeh, Farahnaz Mohammadi Shahboulaghi, Abbas Ebadi, Abbas Ali Keshtkar and Ali Montazeri

    Citation: Systematic Reviews 2019 8:26

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  47. Content type: Research

    Graphic health warnings on tobacco packaging and the plain packaging of tobacco products are key tobacco control interventions. This systematic review investigates the perceptions of adolescents towards these ...

    Authors: Aaron Drovandi, Peta-Ann Teague, Beverley Glass and Bunmi Malau-Aduli

    Citation: Systematic Reviews 2019 8:25

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  48. Content type: Protocol

    Opioids are commonly used for the management of postoperative pain, but their use is limited by important adverse events, such as respiratory depression and the potential for addiction. Multimodal opioid-spari...

    Authors: Michael Verret, François Lauzier, Ryan Zarychanski, Xavier Savard, Marie-Joëlle Cossi, Anne-Marie Pinard, Guillaume Leblanc and Alexis F. Turgeon

    Citation: Systematic Reviews 2019 8:24

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