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  1. Recurrent aphthous stomatitis (RAS) is a common chronic inflammatory oral disease that negatively impacts the quality of life. Current therapies aim to reduce pain and healing process yet challenges such as ra...

    Authors: Desiana Radithia, Fatma Yasmin Mahdani, Reiska Kumala Bakti, Adiastuti Endah Parmadiati, Ajiravudh Subarnbhesaj, Selviana Rizky Pramitha and I Gusti Agung Sri Pradnyani
    Citation: Systematic Reviews 2024 13:192
  2. Dyslipidemia is an imbalance of lipid profiles. It increases the chance of clogged arteries and may cause heart attacks, strokes, and other circulatory disorders. Dyslipidemia affects the general population, b...

    Authors: Abere Woretaw Azagew, Hailemichael Kindie Abate, Chilot Kassa Mekonnen, Habtamu Sewunet Mekonnen, Zewdu Baye Tezera and Gashaw Jember
    Citation: Systematic Reviews 2024 13:190
  3. The COVID-19 pandemic has caused a large mortality and morbidity burden globally. For individuals, a strong immune response is the most effective means to block SARS-CoV-2 infection. To inform clinical case ma...

    Authors: Qiuying Zhang, Lirui Jiao, Qiushi Chen, Caroline A. Bulstra, Pascal Geldsetzer, Tulio de Oliveira, Juntao Yang, Chen Wang, Till Bärnighausen and Simiao Chen
    Citation: Systematic Reviews 2024 13:189
  4. Given the recent evidence on gender differences in the presentation of autism, there is an increasing concern that current tools for autism do not adequately capture traits more often found in women. If tools ...

    Authors: Nora Uglik-Marucha, David Mason, Hannah Belcher, Francesca Happé and Silia Vitoratou
    Citation: Systematic Reviews 2024 13:188
  5. Knee osteoarthritis (KOA) has become a public health issue. Several systematic reviews (SRs) and meta-analyses (MAs) indicate that traditional Chinese exercise (TCE) may be an effective treatment for reducing ...

    Authors: Tao Tao, Ming-peng Shi, Bo-yang Tan, Xian-shuai Zhang, Feng-ling Sun, Bao-ren Liu, Shao-jun Li and Zhen-hua Li
    Citation: Systematic Reviews 2024 13:187
  6. Highlighting the identified gaps in evidence-based research concerning advanced esophageal cancer (EC) treatment and care, this review evaluates the efficacy and safety of anticancer drugs compared to supporti...

    Authors: Marilina Santero, Adriana-Gabriela Meade, Anna Selva, Olga Savall-Esteve, Javier Bracchiglione, Ismael Macías, Leire Leache, Paula Cerdà and Xavier Bonfill Cosp
    Citation: Systematic Reviews 2024 13:186
  7. While numerous studies have reported associations between low dietary potassium intake and adverse clinical outcomes, methods to estimate potassium intake, mainly self-reported dietary measures and urinary pot...

    Authors: Nobuhisa Morimoto, Hasan Jamil, Mohab Alakkari, Yuki Joyama, Tatsuhiko Anzai, Kunihiko Takahashi and Soichiro Iimori
    Citation: Systematic Reviews 2024 13:185
  8. Growing numbers of randomized clinical trials-based systematic reviews and meta-analyses (SRs/MAs) have been conducted to examine the effectiveness of acupuncture in treating gastroesophageal reflux disease (G...

    Authors: Jinke Huang, Jiali Liu, Fengyun Wang and Xudong Tang
    Citation: Systematic Reviews 2024 13:183
  9. A deficiency in iron stores is associated with various adverse health complications, which, if left untreated, can progress to states of anaemia, whereby there is significant detriment to an individual’s work ...

    Authors: Cory Dugan, Peter Peeling, Richard Burden and Toby Richards
    Citation: Systematic Reviews 2024 13:182
  10. Historically, Indigenous voices have been silent in health research, reflective of colonial academic institutions that privilege Western ways of knowing. However, Indigenous methodologies and methods with an e...

    Authors: Wanda Phillips-Beck, Bryden L. J. Bukich, Kellie Thiessen, Josée G. Lavoie, Annette Schultz, Julianne Sanguins, Geraldine Beck, Brenda Longclaws, Geraldine Shingoose, Matta Palmer, Janice Linton, Bekelu Negash and Taylor Morriseau
    Citation: Systematic Reviews 2024 13:181
  11. The emergence of HIV drug resistance presents a substantial challenge. Current antiretroviral treatments, along with current classes, face the danger of becoming partially or entirely inactive. As a result, al...

    Authors: Melashu Balew, Gedefaw Abeje, Alemtsehay Mekonnen and Getu Degu
    Citation: Systematic Reviews 2024 13:180
  12. This overview of reviews aims to identify evidence on the benefits (i.e. tobacco use abstinence and reduction in smoking frequency) and harms (i.e. possible adverse events/outcomes) of smoking cessation interv...

    Authors: Mona Hersi, Andrew Beck, Candyce Hamel, Leila Esmaeilisaraji, Kusala Pussegoda, Bradley Austin, Nadera Ahmadzai, Misty Pratt, Micere Thuku, Fatemeh Yazdi, Alexandria Bennett, Nicole Shaver, Niyati Vyas, Becky Skidmore, Brian Hutton, Douglas Manuel…
    Citation: Systematic Reviews 2024 13:179
  13. Worldwide, the culturally and linguistically diverse (CALD) population is increasing, and is predicted to reach 405 million by 2050. The delivery of emergency care for the CALD population can be complex due to...

    Authors: Ya-Ling Huang, Sarah Thorning, Chun-Chih Lin, Robert Lee, Elizabeth Elder and Julia Crilly
    Citation: Systematic Reviews 2024 13:178
  14. In a time of exponential growth of new evidence supporting clinical decision-making, combined with a labor-intensive process of selecting this evidence, methods are needed to speed up current processes to keep...

    Authors: Wouter Harmsen, Janke de Groot, Albert Harkema, Ingeborg van Dusseldorp, Jonathan de Bruin, Sofie van den Brand and Rens van de Schoot
    Citation: Systematic Reviews 2024 13:177
  15. Software that employs screening prioritization through active learning (AL) has accelerated the screening process significantly by ranking an unordered set of records by their predicted relevance. However, fai...

    Authors: Fionn Byrne, Laura Hofstee, Jelle Teijema, Jonathan De Bruin and Rens van de Schoot
    Citation: Systematic Reviews 2024 13:175
  16. The demand for high-quality systematic literature reviews (SRs) for evidence-based medical decision-making is growing. SRs are costly and require the scarce resource of highly skilled reviewers. Automation tec...

    Authors: Barbara Tóth, László Berek, László Gulácsi, Márta Péntek and Zsombor Zrubka
    Citation: Systematic Reviews 2024 13:174
  17. Giant cell arteritis (GCA) is the most common systemic vasculitis in adults. Presenting features include new-onset headaches, constitutional symptoms, jaw claudication, polymyalgia rheumatica, and visual sympt...

    Authors: Jean-Paul Makhzoum, Youssef Baati, Octavian Tanase, Arielle Mendel, Christian Pagnoux and Carolyn Ross
    Citation: Systematic Reviews 2024 13:173
  18. Allergic rhinitis (AR) is a common inflammatory disease of the nasal mucosa that is characterized by symptoms such as sneezing, nasal congestion, nasal itching, and rhinorrhoea. In recent years, acupoint herba...

    Authors: Ningcong Xu, Claire Shuiqing Zhang, Xi Tan, Yunjie Lai, Yanfang Cen, Shiqing Zhou, Jiyan Xia, Yunying Li and Qiulan Luo
    Citation: Systematic Reviews 2024 13:172
  19. Preserved ratio impaired spirometry (PRISm) is a type of abnormal lung function. PRISm and mortality have been explored in several studies, but a comprehensive evaluation of the associations is limited. The cu...

    Authors: Mengya Li, Mengxin Chen, Yang Li, Zhiguang Liu, Xiaocong Li, Xinyue Lang, Bo Hu and Wei Li
    Citation: Systematic Reviews 2024 13:171
  20. As an emerging technology in robot-assisted (RA) surgery, the potential benefits of its application in transforaminal lumbar interbody fusion (TLIF) lack substantial support from current evidence.

    Authors: Jianbin Guan, Ningning Feng, Xing Yu and Kaitan Yang
    Citation: Systematic Reviews 2024 13:170
  21. The acute and long-term benefits of exercise training on cardiovascular health have been well established. The systematic review and meta-analysis aimed to systematically assess the effectiveness of exercise t...

    Authors: Deshuang Yang, Shiyi Tao, Mingjing Shao, Li Huang, Xiang Xiao, Jin Zhang, Ruiqi Yao and Ziyi Sun
    Citation: Systematic Reviews 2024 13:169
  22. This systematic review aims to identify the benefits and harms of electronic cigarettes (e-cigarettes) as a smoking cessation aid in adults (aged ≥ 18 years) and to inform the development of the Canadian Task ...

    Authors: Niyati Vyas, Alexandria Bennett, Candyce Hamel, Andrew Beck, Micere Thuku, Mona Hersi, Nicole Shaver, Becky Skidmore, Brian Hutton, Douglas Manuel, Matt Morrow, Smita Pakhale, Justin Presseau, Beverley J. Shea, Julian Little, David Moher…
    Citation: Systematic Reviews 2024 13:168
  23. Chemotherapy-related cardiotoxicity is a significant concern because it is a major cause of morbidity. This study aimed to provide in-depth information on the symptoms of chemotherapy-related cardiotoxicity (C...

    Authors: Hyunjoo Kim, Bomi Hong, Sanghee Kim, Seok-Min Kang and Jeongok Park
    Citation: Systematic Reviews 2024 13:167
  24. The steep rise in substance use and substance use disorder (SUD) shows an urgency to assess its prevalence using valid measures. This systematic review summarizes the validity of measures to assess the prevale...

    Authors: Yuni Tang, Erin Caswell, Rowida Mohamed, Natalie Wilson, Edis Osmanovic, Gordon Smith, Summer D. Hartley and Ruchi Bhandari
    Citation: Systematic Reviews 2024 13:166
  25. Non-invasive brain stimulation (NIBS) is a promising intervention for treatment-resistant schizophrenia. However, there are multiple available techniques and a comprehensive synthesis of evidence is lacking. T...

    Authors: Spyridon Siafis, Carolin Lorenz, Hui Wu, Yikang Zhu, Johannes Schneider-Thoma, Irene Bighelli, Chunbo Li, Wulf-Peter Hansen, Frank Padberg, Georgia Salanti and Stefan Leucht
    Citation: Systematic Reviews 2024 13:165
  26. Inflammatory bowel diseases (IBDs) are associated with high healthcare utilization. This systematic review aimed to summarize what is known about the impact of sex, income, and education on the likelihood of b...

    Authors: Nathalie Fogh Rasmussen, Caroline Moos, Laura Helene Keiding Gregersen, Zainab Hikmat, Vibeke Andersen, Anders Green, Tine Jess, Gunvor Iben Madsen, Andreas Kristian Pedersen, Sofie Ronja Petersen and Lene Juel Kjeldsen
    Citation: Systematic Reviews 2024 13:164
  27. This protocol outlines a scoping review with the objective of identifying and exploring planetary health considerations within existing health guidelines and health technology assessments (HTA). The insights g...

    Authors: Thomas Piggott, Maheen Raja, Charlotte T. J. Michels, Alina Herrmann, Karolina Anna Scahill, Andrea J. Darzi, Laura Jewell, KM Saif-Ur-Rahman, Hendrik Napierala, Ruben Heuer, Rebecca L. Morgan, Grigorios I. Leontiadis, Ignacio Neumann, Holger Schünemann and Fiona A. Miller
    Citation: Systematic Reviews 2024 13:163
  28. Telephone triage is used to optimise patient flow in emergency primary healthcare. Poor communication can lead to misunderstandings and compromise patient safety. To improve quality, a comprehensive understand...

    Authors: Siri-Linn Schmidt Fotland, Vivian Midtbø, Jorunn Vik, Erik Zakariassen and Ingrid Hjulstad Johansen
    Citation: Systematic Reviews 2024 13:162
  29. Mindfulness-based interventions (MBIs) appear to be effective for improving the mental health of healthcare professionals (HCPs). However, the effectiveness of MBIs on extreme psychological trauma caused by th...

    Authors: Gemma Benavides-Gil, Fermín Martínez-Zaragoza, Jordi Fernández-Castro, Alicia Sánchez-Pérez and Rosa García-Sierra
    Citation: Systematic Reviews 2024 13:160
  30. Patients with heart failure with preserved ejection fraction (HFpEF) commonly experience exercise intolerance, resulting in reduced cardiorespiratory fitness. This is characterised by a decreased maximal oxyge...

    Authors: Raphael Schoch, Benedikt Gasser, Philippe Beck, Christian Appenzeller-Herzog and Arno Schmidt-Trucksäss
    Citation: Systematic Reviews 2024 13:159
  31. Systematically screening published literature to determine the relevant publications to synthesize in a review is a time-consuming and difficult task. Large language models (LLMs) are an emerging technology wi...

    Authors: Fabio Dennstädt, Johannes Zink, Paul Martin Putora, Janna Hastings and Nikola Cihoric
    Citation: Systematic Reviews 2024 13:158
  32. The use of prophylactic antibiotics in surgery is contentious. With the rise in antimicrobial resistance, evidence-based antibiotic use should be followed. This systematic review and network meta-analysis will...

    Authors: Chen Zhang, Suraya Mohamed Yusuf, Soma Farag, Ryckie George Wade and Justin Conrad Rosen Wormald
    Citation: Systematic Reviews 2024 13:157
  33. Hematopoietic stem cell transplantation (HSCT) is a life-saving treatment for adolescents and young adults (ages 15–39) with hematologic malignancy. Given the significant developmental milestones usually achie...

    Authors: Nikita V. Baclig, Antonia Osuna-Garcia, Vivek Chotai, Patricia A. Ganz and Eden R. Brauer
    Citation: Systematic Reviews 2024 13:156
  34. Due to increasing life expectancy, almost half of people with type 2 diabetes are aged 65 years or over worldwide. When metformin alone does not control blood sugar, the choice of which second-line therapy to ...

    Authors: Jingya Wang, Krishnarajah Nirantharakumar, Christopher Sainsbury, David J. Moore, Alan Sinclair, G. Neil Thomas, Wasim Hanif, Megha Singh, Luyuan Tan, Zhaonan Wang, Nikita Simms-Williams, Mi Yao, M. Niluka Gunathilaka, Pushpa Singh, Konstantinos Toulis, Apostolos Tsapas…
    Citation: Systematic Reviews 2024 13:155
  35. Frailty reduction and reversal have been addressed successfully among older populations within community settings. However, these findings may not be applicable to residential care settings, largely due to the...

    Authors: R. C. Ambagtsheer, M. J. Leach, L. M. O’Brien, J. Tyndall, J. Wardle and J. Beilby
    Citation: Systematic Reviews 2024 13:154
  36. Breast cancer is the most common malignancy among women in the UK. Following mastectomy, reconstruction is now integral to the surgical management of breast cancer, of which implant-based reconstruction (IBBR)...

    Authors: H. Cook, D. Zargaran, S. P. Glynou, S. Hamilton and A. Mosahebi
    Citation: Systematic Reviews 2024 13:153
  37. Despite growing interest in workplace mental health interventions, evidence of their effectiveness is mixed. Implementation science offers a valuable lens to investigate the factors influencing successful impl...

    Authors: Charlotte Paterson, Caleb Leduc, Margaret Maxwell, Birgit Aust, Heather Strachan, Ainslie O’Connor, Fotini Tsantila, Johanna Cresswell-Smith, Gyorgy Purebl, Lars Winter, Naim Fanaj, Asmae Doukani, Bridget Hogg, Paul Corcoran, Luigia D’Alessandro, Sharna Mathieu…
    Citation: Systematic Reviews 2024 13:152
  38. Memory and attention are important for daily functioning, and their function deteriorates due to aging. However, fruit and vegetable consumption are one of the protective factors against deterioration in memor...

    Authors: Khai Ling Khor, Vashnarekha Kumarasuriar, Kok Wei Tan, Pei Boon Ooi and Yook-Chin Chia
    Citation: Systematic Reviews 2024 13:151
  39. Clinical trials investigating acetabular fractures are heterogeneous in their investigated outcomes and their corresponding measurements. Standardization may facilitate comparability and pooling of research re...

    Authors: Denise Schulz, Adrian Deichsel, Martin C. Jordan, Joachim Windolf, Michael J. Raschke and Anne Neubert
    Citation: Systematic Reviews 2024 13:150
  40. Co-production is a collaborative approach to prepare, plan, conduct, and apply research with those who will use or be impacted by research (knowledge users). Our team of knowledge users and researchers sought ...

    Authors: Janet Jull, Maureen Smith, Meg Carley, Dawn Stacey and Ian D. Graham
    Citation: Systematic Reviews 2024 13:149
  41. Due to their adverse environmental and health impacts, brominated flame retardants (BFRs) are listed in Annex A of the Stockholm Convention for global elimination of production and use. Their health impacts in...

    Authors: Rebecca Mlelwa and Hanna-Andrea Rother
    Citation: Systematic Reviews 2024 13:148
  42. Personalised prevention aims to delay or avoid disease occurrence, progression, and recurrence of disease through the adoption of targeted interventions that consider the individual biological, including genet...

    Authors: E Plans-Beriso, C Babb-de-Villiers, D Petrova, C Barahona-López, P Diez-Echave, O R Hernández, N F Fernández-Martínez, H Turner, E García-Ovejero, O Craciun, P Fernández-Navarro, N Fernández-Larrea, E García-Esquinas, I Kuhn, V Jiménez-Planet, V Moreno…
    Citation: Systematic Reviews 2024 13:147
  43. Atrophic edentulous maxilla is a debilitating condition caused by the progressive and irreversible bone resorption following loss of teeth, that results in bone of inadequate volume and density. This makes con...

    Authors: Anisha Rodrigues, Samer Abi-Nader, Robert Durand, Pierre Rompré, Amal Idrissi Janati, Saadet Atsu, Martin Morris and Elham Emami
    Citation: Systematic Reviews 2024 13:146
  44. Functional endoscopic sinus surgery is a principal option for treating chronic rhinosinusitis with nasal polyps (CRSwNP) after medication failures. Unfortunately, some patients still have unsatisfactory postop...

    Authors: Yan Xie, Fangqi Liang, Li Zhou, Qing Chen, Feifei Chen, Qinwei Fu, Shiqi Wu, Dandi Zeng, Wanling Cui, Linzhi Liao and Luyun Jiang
    Citation: Systematic Reviews 2024 13:145
  45. Many healthcare professionals are experiencing psychological distress. Electronic mental health (e-mental health) interventions are convenient and multifunctional. This review aimed to examine the effectivenes...

    Authors: Zemiao Zhang, Yinhuan Hu, Sha Liu, Xiandong Feng, Jinhong Yang, Ling Jie Cheng, Sheena Ramazanu and Xi Vivien Wu
    Citation: Systematic Reviews 2024 13:144
  46. Currently, iodine deficiency has become a significant burden globally; where 2 billion people and 29.8% of school-age children are iodine deficient. It is a leading cause of preventable brain damage among chil...

    Authors: Lemlem Daniel Baffa, Dessie Abebaw Angaw, Zufan Yiheyis Abriham, Moges Gashaw, Muluken Chanie Agimas, Mekonnen Sisay, Esmael Ali Muhammad, Berhanu Mengistu and Aysheshim Kassahun Belew
    Citation: Systematic Reviews 2024 13:142

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