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  1. Patients receiving thoracic aortic repair suffer from long-term impairment in daily functioning and quality of life following intervention due to a combination of their life-threatening condition (i.e. aortic ...

    Authors: Niek Koenders, Henrita van Zetten, Michelle Smulders, Martin L. Verra, Roland R. J. van Kimmenade, Thomas van Brakel, Thijs M. H. Eijsvogels and Tim Smith
    Citation: Systematic Reviews 2023 12:16
  2. Implementing and sustaining innovations in clinical practice, such as evidence-based practices, programmes, and policies, is frequently described as challenging. Facilitation as a strategy for supporting imple...

    Authors: Malin Tistad, Anna Bergström, Marie Elf, Leif Eriksson, Catharina Gustavsson, Camilla Göras, Gill Harvey, Ann-Sofie Källberg, Ann Rudman, Maria Unbeck and Lars Wallin
    Citation: Systematic Reviews 2023 12:15
  3. Colorectal cancer (CRC) is becoming an increasing health problem worldwide. However, with the help of screening, early diagnosis can reduce incidence and mortality rates. To elevate the economic burden that CR...

    Authors: Olivia Adair, Ethna McFerran, Tracy Owen, Christine McKee, Felicity Lamrock and Mark Lawler
    Citation: Systematic Reviews 2023 12:14
  4. Vitamin B deficiencies are involved with several outcomes in fertility and pregnancy. In Brazil, the national prevalence rates of these micronutrient deficiencies in women of reproductive age were not known. T...

    Authors: Michel Carlos Mocellin, Cintia Chaves Curioni, Alessandra da Silva Pereira, Simone Augusta Ribas, Michelle Teixeira Teixeira, Tatiane Salgado Galvão de Macedo and Gabriel Mantolvão Palermo
    Citation: Systematic Reviews 2023 12:13
  5. Unintended pregnancies pose a severe threat to the well-being of HIV-positive women and their unborn children. Factors contributing to the high incidence of unintended pregnancies include contraceptive failure...

    Authors: Oguntade Racheal Tomilola, Ojewole Elizabeth Bolanle and Ogunrombi Modupe Olufunmilayo
    Citation: Systematic Reviews 2023 12:12
  6. The volume-outcome relationship, i.e., higher hospital volume results in better health outcomes, has been established for different surgical procedures as well as for certain nonsurgical medical interventions....

    Authors: Julia Scharfe, Stefanie Pfisterer-Heise, Charlotte Mareike Kugler, Eni Shehu, Tobias Wolf, Tim Mathes and Dawid Pieper
    Citation: Systematic Reviews 2023 12:11
  7. Recent challenges in the working world that resulted from the pandemic and technological advances have underlined the importance of flexibility in how jobs are designed. Job crafting (JC) refers to self-initia...

    Authors: Marta Roczniewska, Anna Rogala, Magdalena Marszałek, Henna Hasson, Arnold B. Bakker and Ulrica von Thiele Schwarz
    Citation: Systematic Reviews 2023 12:10
  8. Chimeric antigen receptor T cell therapy (CAR-T) represents a promising and exciting new therapy for hematologic malignancies, where prognosis for relapsed/refractory patients remains poor. Encouraging results...

    Authors: Manoj M. Lalu, Natasha Kekre, Joshua Montroy, Maryam Ghiasi, Kevin Hay, Scott McComb, Risini Weeratna, Harold Atkins, Brian Hutton, Ayel Yahya, Ashish Masurekar, Mohamad Sobh and Dean A. Fergusson
    Citation: Systematic Reviews 2023 12:9
  9. Scientists, physicians, and the general public legitimately expect scholarly publications to give true answers to study questions raised. We investigated whether findings from studies published in journals wit...

    Authors: Andreas Heidenreich, Nora Eisemann, Alexander Katalinic and Joachim Hübner
    Citation: Systematic Reviews 2023 12:8
  10. Machine learning (ML) tools exist that can reduce or replace human activities in repetitive or complex tasks. Yet, ML is underutilized within evidence synthesis, despite the steadily growing rate of primary st...

    Authors: Ashley Elizabeth Muller, Rigmor C. Berg, Jose Francisco Meneses-Echavez, Heather M. R. Ames, Tiril C. Borge, Patricia Sofia Jacobsen Jardim, Chris Cooper and Christopher James Rose
    Citation: Systematic Reviews 2023 12:7
  11. Measurement of neck muscle strength is common during the assessment of people with chronic neck pain (CNP). This systematic review evaluates the measurement properties (reliability, validity, and responsivenes...

    Authors: Deepa Abichandani, Jonathan Tong Yuk Ting, Edith Elgueta Cancino, Shouq Althobaiti and Deborah Falla
    Citation: Systematic Reviews 2023 12:6
  12. Rett syndrome is a rare, severe neurodevelopmental disorder. Almost all cases occur in girls, in association with spontaneous (non-inherited) mutations involving the methyl-CpG-binding protein 2 gene located on t...

    Authors: Uarda Petriti, Daniel C. Dudman, Emil Scosyrev and Sandra Lopez-Leon
    Citation: Systematic Reviews 2023 12:5
  13. Globally, suicide is the fourth leading cause of adolescent mortality. Although post-primary school-based suicide prevention (PSSP) interventions are an evidence-based strategy for targeting adolescent suicida...

    Authors: Eibhlin H. Walsh, Matthew P. Herring and Jennifer McMahon
    Citation: Systematic Reviews 2023 12:4
  14. Financial burden is a common phenomenon, often noticed in the caregivers of children with Down syndrome. It echoes adverse effects on the caregiver’s mental and physical health. The economic burden covers dire...

    Authors: Jyothi Shetty, Ankitha Shetty, Suneel C. Mundkur, Tantri Keerthi Dinesh and Prachi Pundir
    Citation: Systematic Reviews 2023 12:3
  15. Access to medical rehabilitation remains poor in Sub-Saharan Africa. This is partly due to inadequate service delivery emanating from ill-defined public health policies. Developed countries have adopted public...

    Authors: Senzelwe Mazibuko, Thayananthee Nadasan and Pragashnie Govender
    Citation: Systematic Reviews 2023 12:2
  16. The importance of systematic reviews in collating and summarising available research output on a particular topic cannot be over-emphasized. However, initial screening of retrieved literature is significantly ...

    Authors: Agnes Natukunda and Leacky K. Muchene
    Citation: Systematic Reviews 2023 12:1
  17. Vaccination is essential for the prevention of infectious diseases and has helped to reduce disease-related mortality, such as pneumonia. However, traditional vaccine development is time-consuming and risky. R...

    Authors: Zakia Salod and Ozayr Mahomed
    Citation: Systematic Reviews 2022 11:284
  18. Computerized clinical decision support systems are used by clinicians at the point of care to improve quality of healthcare processes (prescribing error prevention, adherence to clinical guidelines, etc.) and ...

    Authors: Héctor Acosta-García, Ingrid Ferrer-López, Juan Ruano-Ruiz, Bernardo Santos-Ramos and Teresa Molina-López
    Citation: Systematic Reviews 2022 11:283
  19. Postpartum depression has costly consequences for the mother, baby, and society. Numerous pharmacological and non-pharmacological interventions are available for the prevention and treatment of postpartum depr...

    Authors: David Thomas Monks, Basavaraj Ankalagi, Preet Mohinder Singh, Ebony Carter, Michelle Doering, Meg Guard and Shannon Lenze
    Citation: Systematic Reviews 2022 11:282
  20. Sex-specific analysis and reporting may allow a better understanding of intervention effects and can support the decision-making process. Well-conducted systematic reviews (SRs), like those carried out by the ...

    Authors: Alba Antequera, M. Ana Cuadrado-Conde, Emilia Roy-Vallejo, María Montoya-Martínez, Montserrat León-García, Olaya Madrid-Pascual and Sara Calderón-Larrañaga
    Citation: Systematic Reviews 2022 11:281
  21. Postoperative delirium (POD) is common after non-cardiac surgery in older adults and can result in increased risk of adverse outcomes including postoperative cognitive dysfunction (POCD). Pain after surgery is...

    Authors: Maram Khaled, Denise Sabac and Maura Marcucci
    Citation: Systematic Reviews 2022 11:280
  22. Alcohol use is an important risk factor for suicidal behavior, with a heightened risk found among women. The objective of this study is to determine the gender-specific risk of suicidal behaviors (suicide atte...

    Authors: Shannon Lange, Michael Roerecke, Heather Orpana, Courtney Bagge and Jürgen Rehm
    Citation: Systematic Reviews 2022 11:279
  23. The sedative effect of intraoperative sedation in elderly surgery exerts critical influence on the prognosis. Comparison on the safety and efficacy between dexmedetomidine and midazolam in many clinical random...

    Authors: Chunxia Huang, Zunjiang Li, Yingxin Long, Dongli Li, Manhua Huang, Banghan Ding and Wei Zhu
    Citation: Systematic Reviews 2022 11:278
  24. A systematically and transparently prepared research priority-setting process within a specific scientific area is essential in order to develop a comprehensive and progressive evidence-based approach that wil...

    Authors: Hans Lund, Lars Tang, Ingrid Poulsen, Karen la Cour, Merete Bjerrum, Claus Vinther Nielsen and Thomas Maribo
    Citation: Systematic Reviews 2022 11:277
  25. Physical punishment at home and in schools is widespread around the world. Systematic reviews and meta-analyses have synthesized evidence, mostly from high-income countries (HICs), showing that physical punish...

    Authors: Jorge Cuartas, Elizabeth T. Gershoff, Drew Bailey and Dana C. McCoy
    Citation: Systematic Reviews 2022 11:276
  26. Young people with stroke (YPwS) persistently experience challenges with disability, social reintegration, employment, and financial stability to provide for themselves and their families. The aims of this scop...

    Authors: U. Gopaul, M. Charalambous, S. Thilarajah, L. K. Kwah, S. Chapman, M. Bayley and M. Demers
    Citation: Systematic Reviews 2022 11:275
  27. Research overlap and duplication is a recognised problem in the context of both pairwise and network systematic reviews and meta-analyses. As a case study, we carried out a scoping review to identify and exami...

    Authors: David J. Fisher, Sarah Burdett, Claire Vale, Ian R. White and Jayne F. Tierney
    Citation: Systematic Reviews 2022 11:274
  28. Mixed evidence exists regarding the effectiveness of the Chronic Care Model (CCM) with patient outcomes. The aim of this review is to examine the effectiveness of CCM interventions on hemoglobin A1c (HbA1c), syst...

    Authors: Lay Hoon Goh, Chiew Jiat Rosalind Siah, Wilson Wai San Tam, E Shyong Tai and Doris Yee Ling Young
    Citation: Systematic Reviews 2022 11:273
  29. Violence against children (VAC) in the home, or by household members, is a widespread problem with devastating and costly consequences for individuals and societies. In the past two decades, much research has ...

    Authors: Jorge Cuartas, Dana McCoy, Hirokazu Yoshikawa, Michelle Bass, Ana Salazar, Nicholas Metheny and Felicia Knaul
    Citation: Systematic Reviews 2022 11:272
  30. Pandemics, such as COVID-19, are dangerous and socially disruptive. Though no one is immune to COVID-19, older persons often bear the brunt of its consequences. This is particularly true for older women, as th...

    Authors: Zhaohui Su, Ali Cheshmehzangi, Barry L. Bentley, Dean McDonnell, Sabina Šegalo, Junaid Ahmad, Hengcai Chen, Lori Ann Terjesen, Emme Lopez, Shelly Wagers, Feng Shi, Jaffar Abbas, Caifeng Wang, Yuyang Cai, Yu-Tao Xiang and Claudimar Pereira da Veiga
    Citation: Systematic Reviews 2022 11:271
  31. Infection with resistant Pseudomonas aeruginosa (RPA) in the intensive care unit (ICU) is known to be either endogenous or exogenous or both, but the roles of each of these contamination routes are yet to be clar...

    Authors: Serge Eyebe, Hugues C. Nana-Djeunga, Magellan Guewo-Fokeng, Guy Sadeu Wafeu, Marius Zambou Vouking, Salomon Massoda, Christine D. Evina, Aurelia Condomat Zoumabo, Pierre Ongolo-Zogo and Jean-Ralph Zahar
    Citation: Systematic Reviews 2022 11:270
  32. Gastrointestinal (GI) bleeding represents the single most frequent site of anticoagulant-related bleeding. Adverse outcomes after major GI bleeding including mortality are not well characterized and, as a resu...

    Authors: Nicholas L. J. Chornenki, Tobias Tritschler, Fabian Stucki, Roupen Odabashian, Jenneke Leentjens, Faizan Khan, Valentina Ly and Deborah M. Siegal
    Citation: Systematic Reviews 2022 11:269
  33. Feedback is vital to improving trainee competencies in medical education. The challenges of the global COVID-19 pandemic related to social distancing to curb the spread of the virus ignited a rapid transition ...

    Authors: Veena S. Singaram, Chauntelle I. Bagwandeen, Reina M. Abraham, Sandika Baboolal and Dumisa N. A. Sofika
    Citation: Systematic Reviews 2022 11:268
  34. Symptomatic cholelithiasis is a common surgical disease and accounts for half of the over one million cholecystectomies performed in the USA annually. Despite its prevalence, only one prior systematic review h...

    Authors: Rivfka Shenoy, Patrick Kirkland, Joseph E. Hadaya, M. Wynn Tranfield, Michael DeVirgilio, Marcia M. Russell and Melinda Maggard-Gibbons
    Citation: Systematic Reviews 2022 11:267
  35. Vestibular schwannomas are benign tumours for which various treatments are available. We performed a systematic review of prospective controlled trials comparing the patient-relevant benefits and harms of sing...

    Authors: Thomas Jakubeit, Sibylle Sturtz, Dorothea Sow, Wolfram Groß, Christoph Mosch, Mattea Patt, Vera Weingärtner, Jan Boström, Roland Goldbrunner and Martina Markes
    Citation: Systematic Reviews 2022 11:265
  36. Trastuzumab, as the gold standard for HER2-positive BC treatment, was the first-line HER2 targeted drug. However, some studies reported patients benefited more from lapatinib and lapatinib plus trastuzumab the...

    Authors: Ye Yuan, Xumei Liu, Yi Cai and Wenyuan Li
    Citation: Systematic Reviews 2022 11:264
  37. Good glycaemic control is a crucial part of diabetes management. Traditional assessment methods, including HbA1c checks and self-monitoring of blood glucose, can be unreliable and inaccurate. Continuous glucos...

    Authors: Jennifer V. E. Brown, Ramzi Ajjan, Najma Siddiqi and Peter A. Coventry
    Citation: Systematic Reviews 2022 11:263
  38. Up to 35% of older adults present to the emergency department (ED) with delirium or develop the condition during their ED stay. Delirium associated with an ED visit is independently linked to poorer outcomes s...

    Authors: Sarah Filiatreault, Jeremy M. Grimshaw, Sara A. Kreindler, Alecs Chochinov, Janice Linton and Malcolm B. Doupe
    Citation: Systematic Reviews 2022 11:262
  39. Given the high risk of contracting a healthcare-associated infection in long-term care facilities, infection prevention and control are essential for the quality of care and safety of residents and staff. To d...

    Authors: Eric Nguemeleu Tchouaket, Katya Kruglova, Idrissa Beogo, Drissa Sia, Stephanie Robins, Emilie Bélanger, Maripier Jubinville, Catherine Séguin, Kelley Kilpatrick, Sandra Boivin and Josiane Létourneau
    Citation: Systematic Reviews 2022 11:261
  40. An unplanned extubation is the uncontrolled and accidental removal of a breathing tube and is an important quality indicator in pediatric critical care. The objective of this review was to comprehensively synt...

    Authors: Krista Wollny, Sara Cui, Deborah McNeil, Karen Benzies, Simon J. Parsons, Tolulope Sajobi and Amy Metcalfe
    Citation: Systematic Reviews 2022 11:259
  41. The Systematic Review (SR) Toolbox was developed in 2014 to collate tools that can be used to support the systematic review process. Since its inception, the breadth of evidence synthesis methodologies has exp...

    Authors: Eugenie Evelynne Johnson, Hannah O’Keefe, Anthea Sutton and Christopher Marshall
    Citation: Systematic Reviews 2022 11:258
  42. High medicine prices contribute to increasing cost of healthcare worldwide. Many patients with limited resources in sub-Saharan Africa (SSA) are confronted with out-of-pocket charges, constraining their access...

    Authors: Augustina Koduah, Leonard Baatiema, Anna Cronin de Chavez, Anthony Danso-Appiah, Irene A. Kretchy, Irene Akua Agyepong, Natalie King, Timothy Ensor and Tolib Mirzoev
    Citation: Systematic Reviews 2022 11:257
  43. Blood derivatives therapy is a conventional clinical treatment, while the treatment for Alzheimer’s disease (AD) is relatively novel. To provide clinical references for treating AD, this meta-analysis was perf...

    Authors: Zhangcheng Fei, Bo Pan, Renjun Pei, Zhongsheng Chen, Xi Du, Haijun Cao and Changqing Li
    Citation: Systematic Reviews 2022 11:256
  44. Public safety personnel (PSP) are exposed to potentially psychologically traumatic events (PPTE) far more often than the general public, which increases the risk for various post-traumatic stress injuries (PTS...

    Authors: Anees Bahji, Paula M. Di Nota, Dianne Groll, R. Nicholas Carleton and Gregory S. Anderson
    Citation: Systematic Reviews 2022 11:255
  45. Atopic dermatitis (AD) is a chronic, debilitating disease affecting children worldwide. Several studies have shown the disease to be a significant problem which leads to a diminished quality of life (QoL) for ...

    Authors: Abraham Getachew Kelbore, Wendemagegn Enbiale, Anisa Mosam and Jacqueline M. van Wyk
    Citation: Systematic Reviews 2022 11:254
  46. Despite the commendable progress made globally in tobacco control, the world is falling short of achieving a 30% relative reduction in current tobacco use by 2025. The African region remains the least in the e...

    Authors: Divine Darlington Logo, Yeetey Enuameh, George Adjei, Arti Singh, Emmanuel Nakua, Edward Dassah, Felix Boakye Oppong and Ellis Owusu-Dabo
    Citation: Systematic Reviews 2022 11:253
  47. Symptom burden and adverse treatment effects can negatively impact physical function, health-related outcomes, and quality of life in cancer survivors. Resistive exercise that improves skeletal muscle function...

    Authors: Jacqueline K. Dawson, Dong-Woo Kang, Oscar Barnes, Rebekah L. Wilson, Mary K. Norris and Christina M. Dieli-Conwright
    Citation: Systematic Reviews 2022 11:252

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