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  1. Increased circulating endocannabinoids levels are typically associated with aerobic exercise. This phenomenon is associated with a “runner’s high,” a state of euphoria and well-being experienced after a long e...

    Authors: Viviane Bristot, Giorgio Poletto, Débora Maria Russiano Pereira, Melina Hauck, Ione Jayce Ceola Schneider and Aderbal S. Aguiar Jr
    Citation: Systematic Reviews 2022 11:98
    Content type: Protocol Published on:

  2. Violence towards women with disabilities is most commonly perpetrated by current or former intimate partners and more than half of disabled women experience intimate partner violence in their lifetime. Disabil...

    Authors: Karen A. Campbell, Marilyn Ford-Gilboe, Meagan Stanley and Karen MacKinnon
    Citation: Systematic Reviews 2022 11:97
    Content type: Protocol Published on:

  3. Art therapy is a form of complementary therapy to treat a wide variety of health problems. Existing studies examining the effects of art therapy differ substantially regarding content and setting of the interv...

    Authors: Ronja Joschko, Stephanie Roll, Stefan N. Willich and Anne Berghöfer
    Citation: Systematic Reviews 2022 11:96
    Content type: Protocol Published on:

  5. The Coronavirus 2019 pandemic necessitated a rapid uptake of video-based interviewing within the personnel selection process in healthcare. While video-based interviews have been evaluated previously, we ident...

    Authors: Rajajee Selvam, Richard Hu, Reilly Musselman, Isabelle Raiche, Daniel I. McIsaac and Husein Moloo
    Citation: Systematic Reviews 2022 11:94
    Content type: Research Published on:

  6. Anterior cruciate ligament (ACL) rupture is a debilitating knee injury associated with sequela such as joint instability and progressive degeneration. Unfortunately, following surgical ACL reconstruction in ad...

    Authors: Nicholas J. Romanchuk, Holly Livock, Kenneth J. Lukas, Michael J. Del Bel, Daniel L. Benoit and Sasha Carsen
    Citation: Systematic Reviews 2022 11:93
    Content type: Protocol Published on:

  7. Oropharyngeal dysphagia (OD) affects 40–81% of patients after stroke. A recent systematic review on the costs of OD and its main complications showed higher acute and long-term costs for those patients who dev...

    Authors: Sergio Marin, Mateu Serra-Prat, Omar Ortega and Pere Clavé
    Citation: Systematic Reviews 2022 11:92
    Content type: Protocol Published on:

  8. Explanations for health inequalities include material, behavioural and psychosocial pathways. Social relationships are an important determinant of health, and research has consistently found that a lack of sup...

    Authors: Nadia Khaliq, Anne McMunn, Carolina Machuca-Vargas and Anja Heilmann
    Citation: Systematic Reviews 2022 11:91
    Content type: Protocol Published on:

  9. In an unparalleled global response, during the COVID-19 pandemic, 90 countries asked 3.9 billion people to stay home. Yet other countries avoided lockdowns and focused on other strategies, like contact tracing...

    Authors: Carl-Etienne Juneau, Tomas Pueyo, Matt Bell, Genevieve Gee, Pablo Collazzo and Louise Potvin
    Citation: Systematic Reviews 2022 11:90
    Content type: Systematic review update Published on:

  10. Diabetes mellitus is an established risk factor for acute myocardial infarction (AMI). Incidence of AMI in people with diabetes remains significantly higher than in those without diabetes. However, published d...

    Authors: Maria Narres, Tatjana Kvitkina, Heiner Claessen, Ellen Ubach, Georg Wolff, Maria-Inti Metzendorf, Bernd Richter and Andrea Icks
    Citation: Systematic Reviews 2022 11:89
    Content type: Protocol Published on:

  11. Rising demand for healthcare continues to impact all sectors of the health service. As a result of the growing ageing population and the burden of chronic disease, healthcare has become more complex, and the n...

    Authors: Naveed Iqbal, Chi Huynh and Ian Maidment
    Citation: Systematic Reviews 2022 11:88
    Content type: Research Published on:

  12. Combination prevention is currently considered the best approach to combat HIV epidemic. It is based upon the combination of structural, behavioral, and biomedical interventions. Such interventions are frequen...

    Authors: Andrainolo Ravalihasy, Lidia Kardaś-Słoma, Yazdan Yazdanpanah and Valéry Ridde
    Citation: Systematic Reviews 2022 11:87
    Content type: Protocol Published on:

  13. Authors: Stephanie M. Eick, Dana E. Goin, Juleen Lam, Tracey J. Woodruff and Nicholas Chartres
    Citation: Systematic Reviews 2022 11:86
    Content type: Correction Published on:

    The original article was published in Systematic Reviews 2022 11:53

  14. There is currently renewed interest in the use of psychedelic therapy in the treatment of psychiatric disorders, including depression. The proposed systematic review will aim to identify, evaluate and summaris...

    Authors: Lauren Johansen, Paul Liknaitzky, Maja Nedeljkovic, Lisa Mastin-Purcell and Greg Murray
    Citation: Systematic Reviews 2022 11:85
    Content type: Protocol Published on:

  15. Alzheimer’s disease is a neurodegenerative disease characterized by progressive cognitive decline and dysfunction of independent living ability, with huge economic and healthy burden worldwide. However, there ...

    Authors: Diyang Lyu, Min Gong, Yong Zhang and Xuanxin Lyu
    Citation: Systematic Reviews 2022 11:84
    Content type: Protocol Published on:

  17. Stem cell transplantation (SCT) has paved the way for treatment of autoimmune diseases. SCT has been investigated in type 1 diabetes mellitus (T1DM) as an autoimmune-based disorder, but previous studies have n...

    Authors: Sedigheh Madani, Mahdiyeh Amanzadi, Hamid Reza Aghayan, Aria Setudeh, Negar Rezaei, Mahtab Rouhifard and Bagher Larijani
    Citation: Systematic Reviews 2022 11:82
    Content type: Systematic review update Published on:

  18. Whilst there are studies that have systematically reviewed the psychometric properties of quality of life measures for children and young people with intellectual disabilities, these narrowly focus on disease ...

    Authors: Stephanie Maguire, Jenny Davison, Marian McLaughlin and Victoria Simms
    Citation: Systematic Reviews 2022 11:81
    Content type: Protocol Published on:

  19. Prescribed exercise to treat medical conditions and to prepare for surgery is a promising intervention to prevent adverse health outcomes for older adults; however, adherence to exercise programs may be low. O...

    Authors: Julia F. Shaw, Sophie Pilon, Matthieu Vierula and Daniel I. McIsaac
    Citation: Systematic Reviews 2022 11:80
    Content type: Research Published on:

  20. Work-related stress is a common phenomenon, often noticed in the employees of the finance sector. It mirrors counter effects on the wellness of employees, their mental well-being, and physical health. Mindfuln...

    Authors: Tantri Keerthi Dinesh, Ankitha Shetty, Vijay Shree Dhyani, Shwetha T.S and Komal Jenifer Dsouza
    Citation: Systematic Reviews 2022 11:79
    Content type: Protocol Published on:

  21. Vaccination, albeit a necessity in the prevention of infectious diseases, requires appropriate strategies for addressing vaccine hesitancy at an individual and community level. However, there remains a glaring...

    Authors: Prem Singh, Pritu Dhalaria, Satabdi Kashyap, Gopal Krishna Soni, Partha Nandi, Shreeparna Ghosh, Mrinal Kar Mohapatra, Apurva Rastogi and Divya Prakash
    Citation: Systematic Reviews 2022 11:78
    Content type: Research Published on:

  22. In the 2021 Statistics Canada census, 18.5% of the Canadian population were senior (65 years and older), among those 1.7 million (4.5%) were aged 80 years and older. Colorectal cancer (CRC) is the third most c...

    Authors: Richard Hu, Rajajee Selvam, Husein Moloo, Lara Williams, Isabelle Raiche and Reilly Musselman
    Citation: Systematic Reviews 2022 11:77
    Content type: Protocol Published on:

  23. The world is facing an unprecedented systemic shock to population health, the economy and society due to the devastating impact of the COVID-19 pandemic. As with most economic shocks, this is expected to dispr...

    Authors: Elaine Tod, Deborah Shipton, Gerry McCartney, Shifa Sarica, Graeme Scobie, Jane Parkinson, Anne-Marie Bagnall, Julian Manley, Andrew Cumbers, Sarah Deas and James de le Vingne
    Citation: Systematic Reviews 2022 11:76
    Content type: Protocol Published on:

  24. Down syndrome (DS) is a chromosomal anomaly that is characterized by an extra chromosome 21. Ophthalmological manifestations have a high prevalence in patients with DS.

    Authors: Juliana Muñoz-Ortiz, Jesús David Charry-Sánchez, Isabella Bechara-Arango, Mariana Blanco-Becerra, Claudia Talero-Gutiérrez, Marcela Gomez-Suarez and Alejandra de-la-Torre
    Citation: Systematic Reviews 2022 11:75
    Content type: Research Published on:

  25. Human communication is essential for socialising, learning and working. Disabilities and social disadvantage have serious negative consequences on communication which can impact development from early life int...

    Authors: Kristen Abrahams, Rizwana Mallick, Ameer Hohlfeld, Tamzyn Suliaman and Harsha Kathard
    Citation: Systematic Reviews 2022 11:74
    Content type: Protocol Published on:

  27. Salivary gland (SG) hypofunction (objectively reduced saliva flow rate) and xerostomia (subjective sensation of dry mouth) are common and burdensome side effects of radiotherapy to the head and neck region. Cu...

    Authors: Per Marcus Jansson, Charlotte Duch Lynggaard, Amanda Fenger Carlander, Siri Beier Jensen, Bjarke Follin, Cecilie Hoeeg, Birgitte Saima Kousholt, Rasmus Tolstrup Larsen, Christian Grønhøj, Kathrine Kronberg Jakobsen, Susie Rimborg, Anne Fischer-Nielsen, Julia M. L. Menon and Christian von Buchwald
    Citation: Systematic Reviews 2022 11:72
    Content type: Protocol Published on:

  28. Duloxetine is an antidepressant that benefits from a wide range of approval in the elderly population, while its safety for use compared to non-elderly is not clearly assessed. This protocol outlines a systema...

    Authors: Jean-Charles Roy, Chloé Rousseau, Alexis Jutel, Florian Naudet and Gabriel Robert
    Citation: Systematic Reviews 2022 11:71
    Content type: Protocol Published on:

  29. Removing financial barriers and making healthcare accessible to all who need it remains an essential component of the United Nations’ sustainable development goals. Pro-poor healthcare financing schemes are po...

    Authors: Loretta Inkoom, Monica Ansu-Mensah, Vitalis Bawontuo and Desmond Kuupiel
    Citation: Systematic Reviews 2022 11:70
    Content type: Protocol Published on:

  30. The purpose of this protocol is to provide a new systematic review with meta-analysis using the current methodology to compare the effectiveness of multicomponent treatment versus other interventions for patie...

    Authors: Felipe Araya-Quintanilla, Héctor Gutiérrez-Espinoza, Jorge Fuentes, Fernanda Prieto-Lafrentz, Leonardo Pavez, Carlos Cristi-Montero, Iván Cavero-Redondo and Celia Álvarez-Bueno
    Citation: Systematic Reviews 2022 11:69
    Content type: Protocol Published on:

  31. Postpartum depression (PPD) is the most common postpartum psychiatric disorder, affecting 11–15% of new mothers, and initiatives towards early identification and treatment are essential due to detrimental cons...

    Authors: Mette-Marie Zacher Kjeldsen, Alessio Bricca, Xiaoqin Liu, Vibe G. Frokjaer, Kathrine Bang Madsen and Trine Munk-Olsen
    Citation: Systematic Reviews 2022 11:68
    Content type: Protocol Published on:

  32. An increasing number of interventions have focused on leadership development for healthcare managers, among which coaching is a common strategy. The purpose of the present systematic review is to synthesize ev...

    Authors: Shuang Hu, Wenjun Chen, Huiping Hu, Wenqiu Huang, Jia Chen and Jiale Hu
    Citation: Systematic Reviews 2022 11:67
    Content type: Protocol Published on:

  33. Although community-level benefits of health system engagement (i.e., health service planning, delivery, and quality improvement, engaged research and evaluation, and collaborative advocacy) are well establishe...

    Authors: Ginetta Salvalaggio, Lawrence Ferguson, Hannah L. Brooks, Sandra Campbell, Vanessa Gladue, Elaine Hyshka, Linda Lam, Heather Morris, Lara Nixon and Jane Springett
    Citation: Systematic Reviews 2022 11:66
    Content type: Protocol Published on:

  34. Indigenous Peoples experience health inequities across the continuum of health services. Improvements for Indigenous patients and their families during vulnerable experiences with the healthcare system may hav...

    Authors: Samantha L. Bowker, Kienan Williams, Aireen Wingert, Jamie M. Boyd, Melissa L. Potestio, Michelle Gates, Erica Wright and Sean M. Bagshaw
    Citation: Systematic Reviews 2022 11:65
    Content type: Protocol Published on:

  35. The evidence base for the role of dietary protein in maintaining good muscle health in older age is strong; however, the importance of protein source remains unclear. Plant proteins are generally of lower qual...

    Authors: Rachel J. Reid-McCann, Sarah F. Brennan, Michelle C. McKinley and Claire T. McEvoy
    Citation: Systematic Reviews 2022 11:64
    Content type: Protocol Published on:

  36. Atrial fibrillation affects an estimated 33 million individuals worldwide and is a major cause of stroke, heart failure, and death. Anticoagulants substantially reduce the risk of stroke but are also associate...

    Authors: Thibaut Galvain, Ruaraidh Hill, Sarah Donegan, Paulo Lisboa, Gregory Y. H. Lip and Gabriela Czanner
    Citation: Systematic Reviews 2022 11:63
    Content type: Protocol Published on:

  37. Based on the Global Trends report from the United Nations High Commissioner for Refugee, in high-income countries, there are 2.7 refuges per 1000 national population, girls and women account for nearly 50% of ...

    Authors: Sarah DeSa, Akalewold T. Gebremeskel, Olumuyiwa Omonaiye and Sanni Yaya
    Citation: Systematic Reviews 2022 11:62
    Content type: Systematic review update Published on:

  39. Benign prostate hyperplasia (BPH) is the most common urological problem in elderly males. Recent studies have reported polymorphism in various metabolic genes in BPH. However, their association with the suscep...

    Authors: Lin Lin, Pugui Li, Xin Liu, Xiuyuan Xie, Liping Liu, Anjani Kumar Singh and Himanshu Narayan Singh
    Citation: Systematic Reviews 2022 11:60
    Content type: Research Published on:

  40. Low back pain is a disability that occurs worldwide. It is a heterogeneous disorder that affects patients with dominant nociceptive, neuropathic, and central sensitization pain. An important pathophysiology of...

    Authors: Tanawin Nopsopon, Areerat Suputtitada, Irin Lertparinyaphorn and Krit Pongpirul
    Citation: Systematic Reviews 2022 11:59
    Content type: Systematic review update Published on:

  41. The rarity and heterogeneity of pediatric cancers make it difficult to assess risk factors associated with the development of cancer in this group. This also determines the quantity and quality of evidence for...

    Authors: Sehlisiwe Ndlovu, Mbuzeleni Hlongwa and Themba Ginindza
    Citation: Systematic Reviews 2022 11:58
    Content type: Research Published on:

  42. Honorary authorship refers to the practice of naming an individual who has made little or no contribution to a publication as an author. Honorary authorship inflates the output estimates of honorary authors an...

    Authors: Reint Meursinge Reynders, Gerben ter Riet, Nicola Di Girolamo and Mario Malički
    Citation: Systematic Reviews 2022 11:57
    Content type: Protocol Published on:

  43. Increasing pressure to publicise research findings and generate impact, alongside an expectation from funding bodies to go beyond publication within academic journals, has generated interest in alternative met...

    Authors: Jo Thompson Coon, Noreen Orr, Liz Shaw, Harriet Hunt, Ruth Garside, Michael Nunns, Alke Gröppel-Wegener and Becky Whear
    Citation: Systematic Reviews 2022 11:56
    Content type: Methodology Published on:

  46. This letter responds to the US Environmental Protection Agency’s Integrated Risk Information System (IRIS) program letter by Radke et al. (2021) that was published in response to the application of the IRIS ri...

    Authors: Stephanie M. Eick, Dana E. Goin, Juleen Lam, Tracey J. Woodruff and Nicholas Chartres
    Citation: Systematic Reviews 2022 11:53
    Content type: Letter Published on:

    The Correction to this article has been published in Systematic Reviews 2022 11:86

  47. Although simulation-based education (SBE) has become increasingly popular as a mode of teaching in undergraduate nursing courses, its effect on associated student learning outcomes remains ambiguous. Education...

    Authors: Matthew Jackson, Lauren McTier, Laura A. Brooks and Rochelle Wynne
    Citation: Systematic Reviews 2022 11:52
    Content type: Protocol Published on:

  48. Prevention of obesity is economically and sociologically preferable to treatment, with early intervention key to preventing excess weight gain and obesity. The transition from adolescence to young adulthood is...

    Authors: Taylor Jade Willmott, Alieena Mathew, Eve Luck, Sharyn Rundle-Thiele, Julia Carins, Lisa Vincze, Lauren Williams and Lauren Ball
    Citation: Systematic Reviews 2022 11:51
    Content type: Protocol Published on:

  49. An increasing number of systematic reviews (SRs) and meta-analyses (MAs) of clinical trials have begun to investigate the effects of virtual reality (VR) in patients with Parkinson disease (PD). The aim of thi...

    Authors: Yaqin Lu, Yonggui Ge, Wanqiang Chen, Wenting Xing, Lushan Wei, Caixia Zhang and Yusheng Yang
    Citation: Systematic Reviews 2022 11:50
    Content type: Research Published on:

  50. Workloads are increasing and could cause mental stress, e.g., in the form of subjective effort reward imbalance (ERI) and overcommitment (OC). The heart rate variability (HRV) is a valid method for objective m...

    Authors: Beatrice Thielmann, Jonas Hartung and Irina Böckelmann
    Citation: Systematic Reviews 2022 11:48
    Content type: Systematic review update Published on:
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ISSN: 2046-4053