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  1. Methodology

    Toward a comprehensive evidence map of overview of systematic review methods: paper 1—purpose, eligibility, search and data extraction

    Overviews of systematic reviews attempt to systematically retrieve and summarise the results of multiple systematic reviews. Methods for conducting, interpreting and reporting overviews are in their infancy. T...

    Carole Lunny, Sue E. Brennan, Steve McDonald and Joanne E. McKenzie

    Systematic Reviews 2017 6:231

    Published on: 21 November 2017

  2. Research

    A systematic review describing incidence rate and prevalence of dysvascular partial foot amputation; how both have changed over time and compare to transtibial amputation

    Partial foot amputation (PFA) is a common consequence of advanced peripheral vascular disease. Given the different ways incidence rate and prevalence data have been measured and reported, it is difficult to sy...

    Michael P Dillon, Matthew Quigley and Stefania Fatone

    Systematic Reviews 2017 6:230

    Published on: 21 November 2017

  3. Protocol

    Exosomal microRNAs as potential circulating biomarkers in gastrointestinal tract cancers: a systematic review protocol

    Metastasis is the most frequent type of recurrence in gastrointestinal (GI) cancers, and there is an emerging potential for new diagnostic and therapeutic approaches, especially in the cases of metastatic GI c...

    Elmira Gheytanchi, Zahra Madjd, Leila Janani, Arezoo Rasti, Roya Ghods, Fatemeh Atyabi, Mohammad Hossein Asadi Lari and Sadegh Babashah

    Systematic Reviews 2017 6:228

    Published on: 17 November 2017

  4. Protocol

    Prevalence and prognosis of acutely ill patients with organ failure at arrival to hospital: protocol for a systematic review

    Acutely ill patients are a heterogeneous group, and some of these suffer from organ failure. As the prognosis of organ failure improves with early treatment, it is important to identify these patients as early...

    Peter Bank Pedersen, Asbjorn Hrobjartsson, Daniel Lykke Nielsen, Daniel Pilsgaard Henriksen, Mikkel Brabrand and Annmarie Touborg Lassen

    Systematic Reviews 2017 6:227

    Published on: 15 November 2017

  5. Protocol

    Assessment of safety and efficacy of mesenchymal stromal cell therapy in preclinical models of acute myocardial infarction: a systematic review protocol

    Despite advances in treatment, acute myocardial infarction (MI) is still associated with significant morbidity and mortality, especially in patients with extensive damage and scar formation. Based on some prom...

    Carly C. Barron, Manoj M. Lalu, Duncan J. Stewart, Dean Fergusson, Homer Yang, David Moher, Peter Liu, David Mazer, P. J. Devereaux and Lauralyn McIntyre

    Systematic Reviews 2017 6:226

    Published on: 7 November 2017

  6. Protocol

    Effectiveness of interventions during NICU hospitalization on the neurodevelopment of preterm infants: a systematic review protocol

    Previous systematic reviews have examined preterm infants’ long-term neurodevelopment after neonatal intensive care unit (NICU) discharge, although none have explored the effectiveness of interventions on pret...

    Marilyn Aita, Robyn Stremler, Nancy Feeley, Andréane Lavallée and Gwenaëlle De Clifford-Faugère

    Systematic Reviews 2017 6:225

    Published on: 3 November 2017

  7. Protocol

    The role of psychosocial stress in the development of chronic musculoskeletal pain disorders: protocol for a systematic review and meta-analysis

    Psychosocial factors play an important role in chronic musculoskeletal pain disorders. Although psychosocial stress is likely to contribute to the development of chronic musculoskeletal pain, investigations ar...

    Valentina Buscemi, Wei-Ju Chang, Matthew B. Liston, James H. McAuley and Siobhan Schabrun

    Systematic Reviews 2017 6:224

    Published on: 3 November 2017

  8. Research

    Reliability of measurements of the fractured clavicle: a systematic review

    The objective of this systematic review was to evaluate the reliability and reproducibility of measurements of shortening in midshaft clavicle fractures (MSCF) using any available imaging technique.

    Paul Hoogervorst, Gerjon Hannink, Arnoud R. van Geene and Albert van Kampen

    Systematic Reviews 2017 6:223

    Published on: 3 November 2017

  9. Protocol

    The macro-economic determinants of health and health inequalities—umbrella review protocol

    The economic determinants of health have been widely recognised as crucial factors affecting health; however, to date, no comprehensive review has been undertaken to summarise these factors and the ways in whi...

    Yannish Naik, Peter Baker, Ian Walker, Taavi Tillmann, Kristin Bash, Darryl Quantz, Frances Hillier-Brown and Clare Bambra

    Systematic Reviews 2017 6:222

    Published on: 3 November 2017

  10. Methodology

    Putting research in place: an innovative approach to providing contextualized evidence synthesis for decision makers

    The Contextualized Health Research Synthesis Program (CHRSP), developed in 2007 by the Newfoundland and Labrador Centre for Applied Health Research, produces contextualized knowledge syntheses for health-syste...

    Stephen Bornstein, Rochelle Baker, Pablo Navarro, Sarah Mackey, David Speed and Melissa Sullivan

    Systematic Reviews 2017 6:218

    Published on: 2 November 2017

  11. Protocol

    Methodological quality and transparency of clinical practice guidelines for the pharmacological treatment of non-communicable diseases using the AGREE II instrument: a systematic review protocol

    Non-communicable diseases (NCDs) are the leading cause of death worldwide. Clinical practice guidelines (CPGs) constitute an important tool for the promotion of evidence-based health, which may improve healthc...

    Caroline de Godoi Rezende Costa Molino, Eliane Ribeiro, Nicolina Silvana Romano-Lieber, Airton Tetelbom Stein and Daniela Oliveira de Melo

    Systematic Reviews 2017 6:220

    Published on: 2 November 2017

  12. Protocol

    Mobile tablet-based therapies following stroke: a systematic scoping review protocol of attempted interventions and the challenges encountered

    Stroke is a growing global epidemic limiting the ability of millions to function independently due to post-stroke deficits and complications. Although specialized stroke rehabilitation improves the recovery of...

    Michael Pugliese, Dylan Johnson, Dar Dowlatshahi and Tim Ramsay

    Systematic Reviews 2017 6:219

    Published on: 2 November 2017

  13. Research

    Effectiveness of real-time polymerase chain reaction assay for the detection of Mycobacterium tuberculosis in pathological samples: a systematic review and meta-analysis

    Rapid and accurate diagnosis of tuberculosis (TB) is key to manage the disease and to control and prevent its transmission. Many established diagnostic methods suffer from low sensitivity or delay of timely re...

    Emmanuel O. Babafemi, Benny P. Cherian, Lee Banting, Graham A. Mills and Kandala Ngianga II

    Systematic Reviews 2017 6:215

    Published on: 25 October 2017

  14. Protocol

    Understanding the experience of initiating community-based physical activity and social support by people with serious mental illness: a systematic review using a meta-ethnographic approach

    People with long-term serious mental illness live with severe and debilitating symptoms that can negatively influence their health and quality of life, leading to outcomes such as premature mortality, morbidit...

    Helen Quirk, Helen Crank, Deborah Harrop, Emma Hock and Robert Copeland

    Systematic Reviews 2017 6:214

    Published on: 25 October 2017

  15. Research

    Diabetes-related information-seeking behaviour: a systematic review

    Information-seeking behaviour is necessary to improve knowledge on diabetes therapy and complications. Combined with other self-management skills and autonomous handling of the disease, it is essential for ach...

    Silke Kuske, Tim Schiereck, Sandra Grobosch, Andrea Paduch, Sigrid Droste, Sarah Halbach and Andrea Icks

    Systematic Reviews 2017 6:212

    Published on: 24 October 2017

  16. Protocol

    Effectiveness of behavioral change techniques employed in eHealth interventions designed to improve glycemic control in persons with poorly controlled type 2 diabetes: a systematic review and meta-analysis protocol

    The incorporation of Behavioral Change Techniques (BCTs) in eHealth interventions for the management of non-communicable diseases (NCDs), such as type 2 diabetes mellitus (T2DM), might be a promising approach ...

    Mihiretu Kebede, Lara Christianson, Zohaib Khan, Thomas L. Heise and Claudia R. Pischke

    Systematic Reviews 2017 6:211

    Published on: 24 October 2017

  17. Research

    Use of social network analysis methods to study professional advice and performance among healthcare providers: a systematic review

    Social network analysis quantifies and visualizes relationships between and among individuals or organizations. Applications in the health sector remain underutilized. This systematic review seeks to analyze w...

    Kate Sabot, Deepthi Wickremasinghe, Karl Blanchet, Bilal Avan and Joanna Schellenberg

    Systematic Reviews 2017 6:208

    Published on: 23 October 2017

  18. Protocol

    A systematic review protocol on the effectiveness of therapeutic exercises utilised by physiotherapists to improve function in patients with burns

    Therapeutic exercises play a crucial role in the management of burn injuries. The broad objective of this review is to systematically evaluate the effectiveness, safety and applicability to low-income countrie...

    Tapfuma Mudawarima, Matthew Chiwaridzo, Jennifer Jelsma, Karen Grimmer and Faith Chengetayi Muchemwa

    Systematic Reviews 2017 6:207

    Published on: 23 October 2017

  19. Commentary

    Authors’ response to comments from Nachman KE et al.

    Authors’ response to comments letter to the editor from Nachman KE et al.

    Annette M. O’Connor, Brent W. Auvermann, Rungano S. Dzikamunhenga, Julie M. Glanville, Julian P. T. Higgins, Shelley P. Kirychuk, Jan M. Sargeant, Sarah C. Totton, Hannah Wood and Susanna G. Von Essen

    Systematic Reviews 2017 6:210

    Published on: 23 October 2017

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