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Systematic Reviews

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  1. Content type: Protocol

    With an ageing population and increasing numbers of people with life-limiting illness, there is a growing demand for palliative day services. There is a need to measure and demonstrate the quality of these ser...

    Authors: Seán R. O’Connor, Martin Dempster and Noleen K. McCorry

    Citation: Systematic Reviews 2017 6:100

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  2. Content type: Research

    Fibromyalgia (FM) is a chronic, debilitating pain disorder. Dissatisfaction with conventional medicine can lead people with FM to turn to complementary and alternative medicine (CAM). Two previous overviews of...

    Authors: Rachel Perry, Verity Leach, Philippa Davies, Chris Penfold, Andy Ness and Rachel Churchill

    Citation: Systematic Reviews 2017 6:97

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  3. Content type: Protocol

    Parkinson’s disease (PD) is a progressive neurodegenerative condition that has genetic susceptibility, aging, and exposure to certain chemicals as risk factors. In recent decades, epidemiological and experimen...

    Authors: Carolina Vaccari, Regina El Dib and João Lauro V. de Camargo

    Citation: Systematic Reviews 2017 6:98

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  4. Content type: Protocol

    Hyperglycaemia-induced oxidative damage is a well-established factor implicated in the development of diabetic cardiomyopathy (DCM) in diabetic individuals. Some of the well-known characteristics of DCM includ...

    Authors: Phiwayinkosi V. Dludla, Bongani B. Nkambule, Stephanie C. Dias and Rabia Johnson

    Citation: Systematic Reviews 2017 6:96

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  5. Content type: Protocol

    Short and poor sleep have been associated with adverse health outcomes in adults, such as overweight/obesity and type 2 diabetes, especially among women. Women therefore represent an important target for inter...

    Authors: Lydi-Anne Vézina-Im, Jennette Palcic Moreno, Theresa A. Nicklas and Tom Baranowski

    Citation: Systematic Reviews 2017 6:95

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  6. Content type: Protocol

    Clinical supervision by a senior therapist is a very common practice in psychotherapist training and psychiatric care settings. Though clinical supervision is advocated by most educational and governing instit...

    Authors: Sven Alfonsson, Åsa Spännargård, Thomas Parling, Gerhard Andersson and Tobias Lundgren

    Citation: Systematic Reviews 2017 6:94

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  7. Content type: Protocol

    Knowledge translation (KT) activities can reduce the gap between “what is known” and “what is done”. Several factors hinder or facilitate KT activities including individual characteristics and organizational a...

    Authors: Anastasia A. Mallidou, Pat Atherton, Liza Chan, Noreen Frisch, Stephanie Glegg and Gayle Scarrow

    Citation: Systematic Reviews 2017 6:93

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  8. Content type: Protocol

    Elective knee surgery is performed to reduce chronic pain and improve function in degenerate knees. Treatment of acute post-operative pain is suboptimal in 75% of patients despite multimodal analgesic approach...

    Authors: Hasan Raza Mohammad, Marialena Trivella, Thomas W. Hamilton, Louise Strickland, David Murray and Hemant Pandit

    Citation: Systematic Reviews 2017 6:92

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  9. Content type: Protocol

    Endovascular interventional radiology (EIR) is an increasingly popular, mini invasive treatment option for patient with symptomatic vascular disease. The EIR practiced by qualified hands is an effective, well-...

    Authors: Kaoutar Mellouk Aid, Hervé Tchala Vignon Zomahoun, Abdelmajid Soulaymani, Karin Lebascle, Stephane Silvera, Pascal Astagneau and Benoit Misset

    Citation: Systematic Reviews 2017 6:89

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  10. Content type: Protocol

    Over 85% of cervical cancer cases and deaths occur in developing countries. HIV-seropositive women are more likely to develop precancerous lesions that lead to cervical cancer than HIV-negative women. However,...

    Authors: Witness Mapanga, Ahmed Elhakeem, Shingairai A. Feresu, Fresier Maseko and Tsungai Chipato

    Citation: Systematic Reviews 2017 6:91

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  11. Content type: Protocol

    Guidelines and evidence-based drug treatment recommendations are usually based on the results of clinical trials, which have limited generalisability in routine clinical settings due to their restrictive eligi...

    Authors: Weyinmi A. Demeyin, Julia Frost, Obioha C. Ukoumunne, Simon Briscoe and Nicky Britten

    Citation: Systematic Reviews 2017 6:90

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  12. Content type: Protocol

    Gaucher disease (GD) is an autosomal recessive lysosomal storage disorder caused by deficiency in acid beta-glucosidase. GD exhibits a wide clinical spectrum of disease severity with an unpredictable natural c...

    Authors: Tatiana Raskovalova, Patrick B. Deegan, Ruby Yang, Elena Pavlova, Jérome Stirnemann, José Labarère, Ari Zimran, Pramod K. Mistry and Marc Berger

    Citation: Systematic Reviews 2017 6:87

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  13. Content type: Protocol

    Prognosis research is on the rise, its importance recognised because chronic health conditions and diseases are increasingly common and costly. Prognosis systematic reviews are needed to collate and synthesise...

    Authors: Nadia Corp, Joanne L. Jordan, Jill A. Hayden, Emma Irvin, Robin Parker, Andrea Smith and Danielle A. van der Windt

    Citation: Systematic Reviews 2017 6:88

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  14. Content type: Systematic review update

    The objective of this review was to update a systematic review of associations between living near an animal feeding operation (AFO) and human health.

    Authors: Annette M. O’Connor, Brent W. Auvermann, Rungano S. Dzikamunhenga, Julie M. Glanville, Julian P. T. Higgins, Shelley P. Kirychuk, Jan M. Sargeant, Sarah C. Totton, Hannah Wood and Susanna G. Von Essen

    Citation: Systematic Reviews 2017 6:86

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  15. Content type: Protocol

    Learning activities are fundamental for the development of expertise in physiotherapy practice. Continuing professional development (CPD) encompasses formal and informal learning activities undertaken by physi...

    Authors: Edmund Leahy, Lucy Chipchase and Felicity Blackstock

    Citation: Systematic Reviews 2017 6:83

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  16. Content type: Protocol

    Approximately 5 to 10% of critically ill patients transition from acute critical illness to a state of persistent and in some cases chronic critical illness. These patients have unique and complex needs that r...

    Authors: Louise Rose, Laura Istanboulian, Laura Allum, Lisa Burry, Craig Dale, Nicholas Hart, Claire Kydonaki, Pam Ramsay, Natalie Pattison and Bronwen Connolly

    Citation: Systematic Reviews 2017 6:84

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  17. Content type: Protocol

    Experiencing mental ill health adds a layer of complexity for individuals in touch with the justice system and for those responsible for working in the justice service with these individuals, such as frontline...

    Authors: Eddie Kane, Emily Evans and Farhad Shokraneh

    Citation: Systematic Reviews 2017 6:85

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  18. Content type: Protocol

    Spitz nevi are uncommon melanocytic neoplasms found in children. Historically, the diagnosis and management of these tumors has lacked consensus among oncologists, pathologists, plastic surgeons, and dermatolo...

    Authors: Jean Abboud, Michael Stein, Michele Ramien and Claudia Malic

    Citation: Systematic Reviews 2017 6:81

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  19. Content type: Protocol

    Hemorrhage is a major cause of early mortality following a traumatic injury. The progression and consequences of significant blood loss occur quickly as death from hemorrhagic shock or exsanguination often occ...

    Authors: Alexandre Tran, Maher Matar, Ewout W. Steyerberg, Jacinthe Lampron, Monica Taljaard and Christian Vaillancourt

    Citation: Systematic Reviews 2017 6:80

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  20. Content type: Research

    Cochrane primarily aims to systematically review trials of effectiveness that are important to inform clinical decisions. Editorial groups support authors to achieve high-quality reviews and prioritise review ...

    Authors: Jasmin Alloo, Sanya Vallath, Chris Del Mar, Matt Carter, Sarah Thorning and Justin Clark

    Citation: Systematic Reviews 2017 6:82

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  21. Content type: Commentary

    When randomized trials have addressed multiple interventions for the same health problem, network meta-analyses (NMAs) permit researchers to statistically pool data from individual studies including evidence f...

    Authors: L. Mbuagbaw, B. Rochwerg, R. Jaeschke, D. Heels-Andsell, W. Alhazzani, L. Thabane and Gordon H. Guyatt

    Citation: Systematic Reviews 2017 6:79

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  22. Content type: Research

    Previous studies investigating the mental health of migrants have shown mixed results. The increased availability of register data has led to a growing number of register-based studies in this research area. T...

    Authors: Kishan Patel, Anne Kouvonen, Ciara Close, Ari Väänänen, Dermot O’Reilly and Michael Donnelly

    Citation: Systematic Reviews 2017 6:78

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  23. Content type: Protocol

    Alcohol dependence is common and serious cause of social and physical harm. However, the optimal management of those with moderate and severe alcohol dependence in primary and community care after detoxificati...

    Authors: Hung-Yuan Cheng, Roy G. Elbers, Julian P. T. Higgins, Abigail Taylor, Georgina J. MacArthur, Luke McGuinness, Sarah Dawson, José A. López-López, Sean Cowlishaw, Matthew Hickman and David Kessler

    Citation: Systematic Reviews 2017 6:77

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  24. Content type: Protocol

    Alcohol use is the behaviour that has the most significant impact on the mortality and morbidity of young people, and binge drinking is becoming the norm among this population. The burden of disease of binge d...

    Authors: Jennifer Hasselgård-Rowe, Barbara Broers and Dagmar M. Haller

    Citation: Systematic Reviews 2017 6:76

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