Skip to main content

Articles

Page 3 of 44

  1. Biologic drugs such as adalimumab, etanercept, and infliximab represent major first-line and second-line treatments for rheumatoid arthritis (RA) patients. However, their high cost poses a massive burden on he...

    Authors: Bruna O. Ascef, Matheus O. Almeida, Ana Cristina de Medeiros Ribeiro, Danieli C. O. Andrade, Haliton A. de Oliveira Júnior, Tiago V. Pereira and Patrícia C. de Soárez

    Citation: Systematic Reviews 2021 10:205

    Content type: Protocol

    Published on:

  2. Adolescence is a period of rapid physical growth and transition between childhood to adulthood. However, in many developing countries, nutritional and epidemiological transitions are contributing to surging ov...

    Authors: Sachin Shinde, Dongqing Wang and Wafaie W Fawzi

    Citation: Systematic Reviews 2021 10:204

    Content type: Protocol

    Published on:

  3. Infectious diseases such as tuberculosis (TB), malaria and soil-transmitted helminthiasis continue to impose a significant global health burden and socio-economic impact. Globally, minority indigenous people a...

    Authors: Beth Gilmour, Kefyalew Addis Alene, Naomi E. Clarke and Archie C. A. Clements

    Citation: Systematic Reviews 2021 10:203

    Content type: Protocol

    Published on:

  4. The pharmacological treatment of cardiovascular diseases and type 2 diabetes mellitus reduces the risk of cardiovascular events.; however, most patients do not adhere to the treatment. There are several self-r...

    Authors: Henrique Ceretta Oliveira, Daisuke Hayashi Neto, Samantha Dalbosco Lins Carvalho, Rita de Cássia Lopes Barros, Mayza Luzia dos Santos Neves, Carla Renata Silva Andrechuk, Neusa Maria Costa Alexandre and Roberta Cunha Matheus Rodrigues

    Citation: Systematic Reviews 2021 10:202

    Content type: Protocol

    Published on:

  5. Non-steroidal anti-inflammatory drugs (NSAID) have excellent anti-inflammatory and analgesic properties and are extensively used to treat post-traumatic or surgical musculoskeletal pain. Although an extensive ...

    Authors: Haider Al-Waeli, Ana Paula Reboucas, Alaa Mansour, Martin Morris, Faleh Tamimi and Belinda Nicolau

    Citation: Systematic Reviews 2021 10:201

    Content type: Research

    Published on:

  6. Rheumatic heart disease is preventable, yet associated with significant health burden, mostly in low-resourced settings. It is prevalent among children and young adults living in impoverished areas. Primordial...

    Authors: Panduleni Penipawa Shimanda, Tonderai Washington Shumba, Mattias Brunström, Stefan Söderberg, Lars Lindholm, Scholastika Ndatinda Iipinge and Fredrik Norström

    Citation: Systematic Reviews 2021 10:200

    Content type: Protocol

    Published on:

  7. People living with dementia (PLWD) are at significant risk of developing urinary and/or faecal incontinence and are also at risk of functional incontinence or being labelled as being incontinent. Despite the g...

    Authors: Deborah Edwards, Jane Harden, Aled Jones and Katie Featherstone

    Citation: Systematic Reviews 2021 10:199

    Content type: Research

    Published on:

  8. Polypharmacy, often defined as the concomitant use of ≥ 5 medications, has been identified as a significant global public health threat. Aging and multimorbidity are key drivers of polypharmacy and have been l...

    Authors: Ikechi G. Okpechi, Mohammed M. Tinwala, Shezel Muneer, Deenaz Zaidi, Feng Ye, Laura N. Hamonic, Maryam Khan, Naima Sultana, Scott Brimble, Allan Grill, Scott Klarenbach, Cliff Lindeman, Amber Molnar, Dorothea Nitsch, Paul Ronksley, Soroush Shojai…

    Citation: Systematic Reviews 2021 10:198

    Content type: Protocol

    Published on:

  9. Obesity has become a major driver in the burden of chronic diseases. The Canadian Clinical Practice Guidelines recommend a lifestyle intervention for the management and prevention of obesity. This includes beh...

    Authors: Katrina Cachero, Matthew Granger, Rebecca C. Mollard, Nicole Askin, George N. Okoli, Ahmed M. Abou-Setta and Dylan MacKay

    Citation: Systematic Reviews 2021 10:197

    Content type: Protocol

    Published on:

  10. The COVID-19 pandemic caused by SARS-CoV-2 has highlighted consistent inequities in incidence, disease severity, and mortality across racial and ethnic minority populations in the United States (US) and beyond...

    Authors: Neia Prata Menezes, Jowanna Malone, Carrie Lyons, Kechna Cadet, Lorraine Dean, Gregorio Millett and Stefan Baral

    Citation: Systematic Reviews 2021 10:196

    Content type: Protocol

    Published on:

  11. Precarious employment is a significant determinant of population health and health inequities and has complex public health consequences both for a given nation and internationally. Precarious employment is co...

    Authors: Virginia Gunn, Carin Håkansta, Emilia Vignola, Nuria Matilla-Santander, Bertina Kreshpaj, David H. Wegman, Christer Hogstedt, Emily Q. Ahonen, Carles Muntaner, Sherry Baron and Theo Bodin

    Citation: Systematic Reviews 2021 10:195

    Content type: Protocol

    Published on:

  12. Comprehensive evidence synthesis on the associations between comorbidities and behavioural factors with hospitalisation, intensive care unit (ICU) admission, and death due to COVID-19 is required for deriving ...

    Authors: Nathalie Verónica Fernández Villalobos, Jördis Jennifer Ott, Carolina Judith Klett-Tammen, Annabelle Bockey, Patrizio Vanella, Gérard Krause and Berit Lange

    Citation: Systematic Reviews 2021 10:194

    Content type: Systematic review update

    Published on:

  13. Social media has been used to disseminate the contents of scientific articles. To measure the impact of this, a new tool called Altmetric was created. Altmetric aims to quantify the impact of each article through...

    Authors: Amanda Costa Araujo, Adriane Aver Vanin, Dafne Port Nascimento, Gabrielle Zoldan Gonzalez and Leonardo Oliveira Pena Costa

    Citation: Systematic Reviews 2021 10:193

    Content type: Research

    Published on:

  14. An assessment of the validity of individual diagnostic accuracy studies in systematic reviews is necessary to guide the analysis and the interpretation of results. Such an assessment is performed for each incl...

    Authors: Yasaman Vali, Mariska M. G. Leeflang and Patrick M. M. Bossuyt

    Citation: Systematic Reviews 2021 10:191

    Content type: Methodology

    Published on:

  15. Improving evidence-informed policy dialogue to support the development and implementation of national health policies is vital, but there is limited evidence on researchers’ roles in policy dialogue processes ...

    Authors: Doris Yimgang, Georges Danhoundo, Elizabeth Kusi-Appiah, Vijit Sunder, Sandra Campbell and Sanni Yaya

    Citation: Systematic Reviews 2021 10:190

    Content type: Systematic review update

    Published on:

  16. Healthcare and human services increasingly rely on teams of individuals to deliver services. Implementation of evidence-based practices and other innovations in these settings requires teams to work together t...

    Authors: Elizabeth A. McGuier, David J. Kolko, Mary Lou Klem, Jamie Feldman, Grace Kinkler, Matthew A. Diabes, Laurie R. Weingart and Courtney Benjamin Wolk

    Citation: Systematic Reviews 2021 10:189

    Content type: Protocol

    Published on:

  17. Parkinson’s disease (PD) is the second most common age-dependent neurodegenerative disease that causes motor and cognitive disabilities. This disease is associated with a loss of dopamine content within the pu...

    Authors: Aliasghar Karimi, Mitra Elmi, Zahra Shiri and Hossein Baharvand

    Citation: Systematic Reviews 2021 10:188

    Content type: Protocol

    Published on:

  18. Many studies have evaluated the effects that a lack of resources has in children’s physical and cognitive development. Although there are reviews that have focused on applied interventions from different persp...

    Authors: Rosalba Company-Córdoba, Antonio Sianes, Ian Craig Simpson and Joaquín A. Ibáñez-Alfonso

    Citation: Systematic Reviews 2021 10:187

    Content type: Protocol

    Published on:

  19. Low birth weight might affect adverse health outcomes during a lifetime. Our study analyzes the association between low birth weight and negative health outcomes during adulthood in twin populations.

    Authors: Sapha Hassan, Shayesteh Jahanfar, Joseph Inungu and Jeffrey M. Craig

    Citation: Systematic Reviews 2021 10:186

    Content type: Systematic review update

    Published on:

  20. Polypharmacy is inevitable and appropriate for many conditions, but in some cases, it can be problematic resulting in an increased risk of harm and reduced quality of life. There has been an increasing interes...

    Authors: Rik S. van der Veen, Joseph J. Lee, Richard J. McManus, Richard F. D. Hobbs, Kamal R. Mahtani, Constantinos Koshiaris and James P. Sheppard

    Citation: Systematic Reviews 2021 10:185

    Content type: Protocol

    Published on:

  21. Health promotion efforts among African American men have been met with significant challenges and have produced limited results. Interventions that do not align with the values, perspectives, and preferences o...

    Authors: Guillermo M. Wippold, Sarah Grace Frary, Demetrius Abshire and Dawn K. Wilson

    Citation: Systematic Reviews 2021 10:184

    Content type: Protocol

    Published on:

  22. Separately, mental and musculoskeletal disorders (MSDs) are prevalent across the life course and are leading contributors to disability worldwide. While people with personality disorder (PD) have been shown to...

    Authors: Shae E. Quirk, Heli Koivumaa-Honkanen, Risto Honkanen, Jeremi Heikkinen, Bianca E. Kavanagh and Lana J. Williams

    Citation: Systematic Reviews 2021 10:182

    Content type: Protocol

    Published on:

  23. Obesity is a prevalent, complex, progressive and relapsing chronic disease characterised by abnormal or excessive body fat that impairs health and quality of life. It affects more than 650 million adults world...

    Authors: Emma Farrell, Marta Bustillo, Carel W. le Roux, Joe Nadglowski, Eva Hollmann and Deirdre McGillicuddy

    Citation: Systematic Reviews 2021 10:181

    Content type: Protocol

    Published on:

  24. Cancer is a non-communicable disease and is the number 2 leading cause of death globally. Among all cancers, cervical cancer is the number 1 killer of women in low-income countries (LICs). Cervical cancer is a...

    Authors: Petmore Zibako, Mbuzeleni Hlongwa, Nomsa Tsikai, Sarah Manyame and Themba G. Ginindza

    Citation: Systematic Reviews 2021 10:180

    Content type: Protocol

    Published on:

  25. People living with all stages of dementia should have the opportunity to participate in meaningful occupations. For those living in care homes, this may not always occur and residents may spend significant par...

    Authors: Nicholas Luscombe, Sarah Morgan-Trimmer, Sharon Savage and Louise Allan

    Citation: Systematic Reviews 2021 10:179

    Content type: Protocol

    Published on:

  26. The aspects of marriage and relationship and their effect on couples’ satisfaction are essential and critical aspects to be explored in this globalized and contemporary world. Since there are no reported meta-...

    Authors: Zeinab Javadivala, Hamid Allahverdipour, Mohammad Asghari Jafarabadi, Somaye Azimi, Neda Gilani and Vijay Kumar Chattu

    Citation: Systematic Reviews 2021 10:178

    Content type: Research

    Published on:

  27. Anemia is common in neurocritically ill patients. Considering the limited clinical evidence in this population, preclinical data may provide some understanding of the potential impact of anemia and of red bloo...

    Authors: Mathieu Laflamme, Hourmazd Haghbayan, Manoj M. Lalu, Ryan Zarychanski, François Lauzier, Amélie Boutin, Malcolm R. Macleod, Dean A. Fergusson, Lynne Moore, Olivier Costerousse, Jacques Lacroix, Cheryl Wellington, Jamie Hutchison and Alexis F. Turgeon

    Citation: Systematic Reviews 2021 10:177

    Content type: Protocol

    Published on:

  28. Caesarean sections often have no urgent indication and are electively planned. Research showed that elective caesarean section should not be performed until 39 + (0–6) weeks of gestation to ensure best neonata...

    Authors: Barbara Prediger, Anahieta Heu-Parvaresch, Stephanie Polus, Stefanie Bühn, Edmund A. M. Neugebauer and Pieper Dawid

    Citation: Systematic Reviews 2021 10:176

    Content type: Research

    Published on:

  29. Tuberculosis (TB) is still one of the leading causes of death worldwide. Genetic studies have pointed to the relevance of the NOD2 and CD14 polymorphic alleles in association with the risk of diseases caused by M...

    Authors: Juan M. Cubillos-Angulo, Catarina D. Fernandes, Davi N. Araújo, Cristinna A. Carmo, María B. Arriaga and Bruno B. Andrade

    Citation: Systematic Reviews 2021 10:174

    Content type: Research

    Published on:

  30. Current clinical guidelines recommend conservative management including non-pharmacologic therapy prior to considering surgery for knee OA. There is a paucity of clinical trials investigating the use of biomec...

    Authors: Michael J. Callaghan, Elizabeth Palmer and Terence O’Neill

    Citation: Systematic Reviews 2021 10:173

    Content type: Research

    Published on:

  31. Utilization of post-abortion family planning is very critical to reduce high levels of unintended pregnancy, which is the root cause of induced abortion. In Eastern Africa, it is estimated that as many as 95% ...

    Authors: Asmamaw Demis Bizuneh and Getnet Gedefaw Azeze

    Citation: Systematic Reviews 2021 10:172

    Content type: Research

    Published on:

  32. Major depression significantly impairs quality of life, increases the risk of suicide, and poses tremendous economic burden on individuals and societies. Duloxetine, a serotonin norepinephrine reuptake inhibit...

    Authors: Faiza Siddiqui, Marija Barbateskovic, Sophie Juul, Kiran Kumar Katakam, Klaus Munkholm, Christian Gluud and Janus Christian Jakobsen

    Citation: Systematic Reviews 2021 10:171

    Content type: Protocol

    Published on:

  33. Substantial literature has highlighted the importance of patient-reported outcome and experience measures (PROMs and PREMs, respectively) to collect clinically relevant information to better understand and add...

    Authors: Angela C. Wolff, Andrea Dresselhuis, Samar Hejazi, Duncan Dixon, Deborah Gibson, A. Fuchsia Howard, Sarah Liva, Barbara Astle, Sheryl Reimer-Kirkham, Vanessa K. Noonan and Lisa Edwards

    Citation: Systematic Reviews 2021 10:169

    Content type: Protocol

    Published on:

  34. Cancer diagnosis in childhood or adolescence impacts significantly on school attendance, experience and educational outcomes. While there is longstanding recognition in clinical practice that these effects spa...

    Authors: Gemma Bryan, Paula Kelly, Heather Chesters, Jayne Franklin, Helen Griffiths, Loveday Langton, Luke Langton, Claire E. Wakefield and Faith Gibson

    Citation: Systematic Reviews 2021 10:167

    Content type: Protocol

    Published on:

  35. Sleep disturbances constitute a common complication in pediatric cancer patients and survivors and are frequently severe enough to warrant treatment. Suboptimal sleep has been associated with decreased emotion...

    Authors: Peter L. Stavinoha, Ineke M. Olsthoorn, Maria C. Swartz, Sara Nowakowski, Stephanie J. Wells, Rachel S. Hicklen, Irtiza Sheikh and Hannah J. Jang

    Citation: Systematic Reviews 2021 10:166

    Content type: Protocol

    Published on:

  36. People with intellectual disabilities have been historically excluded from decision-making processes. Previous literature indicates that increasing social participation may be an effective way to address this ...

    Authors: Andrés Aparicio, Paulina Arango, Rosario Espinoza, Vicente Villate and Marcela Tenorio

    Citation: Systematic Reviews 2021 10:165

    Content type: Protocol

    Published on:

  37. Health systems are often fragmented in low- and middle-income countries (LMICs). This can increase inefficiencies and restrict progress towards universal health coverage. The objective of the systematic review...

    Authors: Marina Siqueira, Maíra Coube, Christopher Millett, Rudi Rocha and Thomas Hone

    Citation: Systematic Reviews 2021 10:164

    Content type: Protocol

    Published on:

  38. Hyperhidrosis is a chronic skin condition that impairs the patient’s quality of life (QoL). There are several patient-reported outcome measures (PROMs) for patients affected by hyperhidrosis available; however...

    Authors: Michaela Gabes, Helge Knüttel and Christian J. Apfelbacher

    Citation: Systematic Reviews 2021 10:163

    Content type: Protocol

    Published on:

  39. Building a dataset of individual participant data (IPD) for meta-analysis represents considerable research investment as well as collaboration across multiple institutions and researchers. Making arrangements ...

    Authors: Nancy Medley, Anna Cuthbert, Richard Crew, Lesley Stewart, Catrin Tudur Smith and Zarko Alfirevic

    Citation: Systematic Reviews 2021 10:162

    Content type: Commentary

    Published on:

  40. Due to the diversity of studies in animal models reporting that molecular mechanisms are involved in the teratogenic effect of the Zika virus (ZIKV), the objective of the present study is to evaluate the metho...

    Authors: Gabriela Elis Wachholz, Julia do Amaral Gomes, Juliano André Boquett, Fernanda Sales Luiz Vianna, Lavínia Schuler-Faccini and Lucas Rosa Fraga

    Citation: Systematic Reviews 2021 10:160

    Content type: Protocol

    Published on:

  41. The prevalence of epilepsy in pregnant women is estimated at 0.3-1%. Anti-epileptic drug (AED) exposure in-utero has been associated with various adverse health outcomes in neonates, including adverse birth we...

    Authors: Alekhya Lavu, Christine Vaccaro, Walid Shouman, Silvia Alessi Severini and Sherif Eltonsy

    Citation: Systematic Reviews 2021 10:159

    Content type: Protocol

    Published on:

  42. The overuse of prescribed antimicrobials, concurrent use of traditional medicine, and prescribed antimicrobials have led to antimicrobial resistance. The absence of collaboration between traditional health pra...

    Authors: Aganze Gloire-Aimé Mushebenge, Mukanda Gedeon Kadima, Tivani Mashamba-Thompson and Manimbulu Nlooto

    Citation: Systematic Reviews 2021 10:158

    Content type: Protocol

    Published on:

  43. Dzherelo (Immunoxel) is one of the few approved immunomodulators that has been shown to produce positive treatment outcomes in patients with tuberculosis (TB). The aim of this review was to assess the effectiv...

    Authors: Marcel Kitenge, Bessie Phiri, Sara M. Pheeha, Modupe Ogunrombi and Peter S. Nyasulu

    Citation: Systematic Reviews 2021 10:157

    Content type: Research

    Published on:

  44. Current text mining tools supporting abstract screening in systematic reviews are not widely used, in part because they lack sensitivity and precision. We set out to develop an accessible, semi-automated “work...

    Authors: Ba’ Pham, Jelena Jovanovic, Ebrahim Bagheri, Jesmin Antony, Huda Ashoor, Tam T. Nguyen, Patricia Rios, Reid Robson, Sonia M. Thomas, Jennifer Watt, Sharon E. Straus and Andrea C. Tricco

    Citation: Systematic Reviews 2021 10:156

    Content type: Research

    Published on:

Annual Journal Metrics