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  1. Total hip and knee arthroplasty are a highly performed surgery; however, patient satisfaction with surgery results and patient involvement in the decision-making process remains low. Patient decision aids (PtD...

    Authors: Lissa Pacheco-Brousseau, Marylène Charette, Dawn Stacey and Stéphane Poitras
    Citation: Systematic Reviews 2021 10:8
  2. The antioxidant potential of vitamin C is useful in reducing oxidative stress, free radicals, and reactive oxygen species, which may assist in the improved outcomes of periodontal therapy. This systematic revi...

    Authors: Hytham N. Fageeh, Hammam I. Fageeh, Ashwin Prabhu, Shilpa Bhandi, Shahrukh Khan and Shankargouda Patil
    Citation: Systematic Reviews 2021 10:5
  3. To inform recommendations by the Canadian Task Force on Preventive Health Care on screening in primary care for the prevention and early detection of cervical cancer by systematically reviewing evidence of (a)...

    Authors: Allison Gates, Jennifer Pillay, Donna Reynolds, Rob Stirling, Gregory Traversy, Christina Korownyk, Ainsley Moore, Guylène Thériault, Brett D. Thombs, Julian Little, Catherine Popadiuk, Dirk van Niekerk, Diana Keto-Lambert, Ben Vandermeer and Lisa Hartling
    Citation: Systematic Reviews 2021 10:2
  4. Population health (PH) research capacity and performance are essential pillars of evidence-based practice to help address health inequalities. Best evidence is provided by systematic reviews (SRs). None of the...

    Authors: Karima Chaabna, Sohaila Cheema, Amit Abraham, Patrick Maisonneuve, Albert B. Lowenfels and Ravinder Mamtani
    Citation: Systematic Reviews 2021 10:1
  5. Despite existing research on text mining and machine learning for title and abstract screening, the role of machine learning within systematic literature reviews (SLRs) for health technology assessment (HTA) r...

    Authors: E. Popoff, M. Besada, J. P. Jansen, S. Cope and S. Kanters
    Citation: Systematic Reviews 2020 9:293
  6. Despite the increase in the number of people accessing antiretroviral therapy (ART), there is limited data regarding treatment failure and its related factors among HIV-positive individuals enrolled in HIV car...

    Authors: Yishak Lailulo, Marcel Kitenge, Shahista Jaffer, Omololu Aluko and Peter Suwirakwenda Nyasulu
    Citation: Systematic Reviews 2020 9:292
  7. Bone is a plastic tissue that is responsive to its physical environment. As a result, exercise interventions represent a potential means to influence the bone. However, little is currently known about how vari...

    Authors: E. Dolan, A. Dumas, K. M. Keane, G. Bestetti, L. H. M. Freitas, B. Gualano, W. Kohrt, G. A. Kelley, R. M. R. Pereira, C. Sale and P. Swinton
    Citation: Systematic Reviews 2020 9:291
  8. Economic evaluations help decision-makers faced with tough decisions on how to allocate resources. Systematic reviews of economic evaluations are useful as they allow readers to assess whether interventions ha...

    Authors: Gemma E. Shields and Jamie Elvidge
    Citation: Systematic Reviews 2020 9:289
  9. The disease burden caused by type 2 diabetes mellitus is a prime public health concern. The prevalence and rate of deaths from diabetes mellitus in low- and middle-income countries (LMICs) are higher than the ...

    Authors: Anupam Sarker, Rina Das, Saraban Ether and K. M. Saif-Ur-Rahman
    Citation: Systematic Reviews 2020 9:288
  10. Critically ill patients receiving invasive ventilation are at risk of sputum retention. Mechanical insufflation-exsufflation (MI-E) is a technique used to mobilise sputum and optimise airway clearance. Recentl...

    Authors: Ema Swingwood, Willemke Stilma, Lyvonne Tume, Fiona Cramp, Frederique Paulus, Marcus Schultz, Wilma Scholte op Reimer and Louise Rose
    Citation: Systematic Reviews 2020 9:287
  11. Although mindfulness-based interventions (MBIs) are becoming increasingly popular, the application of MBIs with children and adolescents is still in its infancy. Mapping the existing literature is necessary to...

    Authors: Marie-France Perrier, Nalia Gurgel-Juarez, Heather Leslie Flowers, Anna McCormick and Sarah J. Short
    Citation: Systematic Reviews 2020 9:286
  12. FMS-like tyrosine kinase 3 (FLT3) is the most frequent mutation in AML. With two FLT3 inhibitors recently approved by the FDA (midostaurin and gilteritinib), there is a need to evaluate these targeted agents.

    Authors: S. Majothi, D. Adams, J. Loke, S. P. Stevens, K. Wheatley and J. S. Wilson
    Citation: Systematic Reviews 2020 9:285
  13. Loneliness is a highly prevalent, harmful, and aversive experience which is fundamentally subjective: social isolation alone cannot account for loneliness, and people can experience loneliness even with ample ...

    Authors: Phoebe E. McKenna-Plumley, Jenny M. Groarke, Rhiannon N. Turner and Keming Yang
    Citation: Systematic Reviews 2020 9:284
  14. Young people’s use of pornography and participation in sexting are commonly viewed as harmful behaviours. This paper reports findings from a ‘review of reviews’, which aimed to systematically identify and synt...

    Authors: Gary Raine, Claire Khouja, Rachel Scott, Kath Wright and Amanda J. Sowden
    Citation: Systematic Reviews 2020 9:283
  15. Diabetes is a major public health issue and there is a need to develop low-cost, novel interventions to prevent or reduce disease progression. Growing evidence shows that supplementation with carnosine, or its...

    Authors: Joseph J. Matthews, Eimear Dolan, Paul A. Swinton, Livia Santos, Guilherme G. Artioli, Mark D. Turner, Kirsty J. Elliott-Sale and Craig Sale
    Citation: Systematic Reviews 2020 9:282
  16. Professionalism is a core competency of medical residents in residency programs. Unprofessional behavior has a negative influence on patient safety, quality of care, and interpersonal relationships. The object...

    Authors: Saeideh Ghaffarifar, Azam Asghari-Khatooni, Amirhossein Akbarzadeh, Ahmad Pourabbas, Mehran Seif Farshad, Rasoul Masoomi and Fariborz Akbarzadeh
    Citation: Systematic Reviews 2020 9:281
  17. People aged ≥ 65 years comprise around 1 in 5 emergency department (ED) presentations. Many of these presentations occur due to complications associated with chronic diseases and frailty. This review aims to p...

    Authors: Ya-Ling Huang, Megan McGonagle, Rebecca Shaw, Julie Eastham, Nemat Alsaba and Julia Crilly
    Citation: Systematic Reviews 2020 9:280
  18. Liver resection (LR) in patients with liver metastasis from colorectal cancer remains the only curative treatment. Perioperative chemotherapy improves prognosis of these patients. However, there are concerns r...

    Authors: Mihai-Calin Pavel, Raquel Casanova, Laia Estalella, Robert Memba, Erik Llàcer-Millán, Mar Achalandabaso, Elisabet Julià, Justin Geoghegan and Rosa Jorba
    Citation: Systematic Reviews 2020 9:279
  19. Sub-Saharan Africa (SSA) homes most of the people living with HIV/AIDS in the world. Adolescents/young people are a vulnerable population and at high risk of HIV infection. Identifying and bridging the researc...

    Authors: Patience Adzordor, Clement Avoka, Vitalis Bawontuo, Silas Agbesi and Desmond Kuupiel
    Citation: Systematic Reviews 2020 9:278
  20. The challenge of implementing evidence-based innovations within practice settings is a significant public health issue that the field of implementation research (IR) is focused on addressing. Significant amoun...

    Authors: Bryan R. Garner, Sheila V. Patel and M. Alexis Kirk
    Citation: Systematic Reviews 2020 9:277
  21. Colorectal cancer (CRC) is a major cause of cancer deaths worldwide. Accumulating evidence suggests a potentially important role of colorectal infection with Fusobacterium nucleatum (F. nucleatum) in colorectal c...

    Authors: Amal Idrissi Janati, Igor Karp, Claudie Laprise, Hisham Sabri and Elham Emami
    Citation: Systematic Reviews 2020 9:276
  22. Health information technology (HIT) is known to reduce prescribing errors but may also cause new types of technology-generated errors (TGE) related to data entry, duplicate prescribing, and prescriber alert fa...

    Authors: Joan Devin, Brian J. Cleary and Shane Cullinan
    Citation: Systematic Reviews 2020 9:275
  23. We evaluated the benefits and risks of using the Abstrackr machine learning (ML) tool to semi-automate title-abstract screening and explored whether Abstrackr’s predictions varied by review or study-level char...

    Authors: Allison Gates, Michelle Gates, Daniel DaRosa, Sarah A. Elliott, Jennifer Pillay, Sholeh Rahman, Ben Vandermeer and Lisa Hartling
    Citation: Systematic Reviews 2020 9:272
  24. Robust diagnosis of dementia requires an understanding of the accuracy of the available diagnostic tests. Informant questionnaires are frequently used to assess for dementia in clinical practice. Recent system...

    Authors: Martin Taylor-Rowan, Sara Nafisi, Amit Patel, Jennifer K. Burton and Terry J. Quinn
    Citation: Systematic Reviews 2020 9:271
  25. The knowledge about the experience of informal caregivers who provide care to people with moderate to advanced dementia in a domestic home setting is limited. A consequence of long hours of caregiving in addit...

    Authors: Charles James, Catherine Walshe and Katherine Froggatt
    Citation: Systematic Reviews 2020 9:270
  26. Acute bronchiolitis caused by respiratory syncytial virus (RSV) has been associated with greater risk of recurrent wheezing and asthma. However, it is unclear whether this association is causal. RSV-specific m...

    Authors: Lauren Alexandra Quinn, Michael D. Shields, Ian Sinha and Helen E. Groves
    Citation: Systematic Reviews 2020 9:269
  27. Rehabilitation research does not always improve patient outcomes because of difficulties implementing complex health interventions. Identifying barriers and facilitators to implementation fidelity is critical....

    Authors: Jain Anne Holmes, Philippa Logan, Richard Morris and Kathryn Radford
    Citation: Systematic Reviews 2020 9:268
  28. Descriptive norms messaging interventions are used to motivate people to adopt or maintain desirable behaviors. Such interventions provide people with information that describes an undesirable behavior as unco...

    Authors: Jinyi Kuang, Maryann G. Delea, Erik Thulin and Cristina Bicchieri
    Citation: Systematic Reviews 2020 9:267
  29. Human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) continue to be a major public health issue, especially in sub-Sahara Africa (SSA). Literature shows significant HIV st...

    Authors: Clement Avoka, Patience Adzordor, Vitalis Bawontuo, Diana A. Akila and Desmond Kuupiel
    Citation: Systematic Reviews 2020 9:266
  30. The prevalence of type-2 diabetes mellitus (T2DM) has been increasing globally. Without proper management, T2DM can develop into serious complications and even death. Diet modification is one of the most effec...

    Authors: Lew Leong Chen, Arimi Fitri Mat Ludin, Suzana Shahar, Zahara Abdul Manaf and Noorlaili Mohd Tohit
    Citation: Systematic Reviews 2020 9:265
  31. Flexor tendon injuries most commonly occur following a penetrating injury to the hand or wrist. These are challenging injuries and the standard treatment is surgical repair under general or regional anaesthesia.

    Authors: Grant S. Nolan, Ailbhe L. Kiely, Tomas Madura and Alexia Karantana
    Citation: Systematic Reviews 2020 9:264
  32. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19) which has rapidly spread worldwide. Several human randomized clinical trials assessing potential vaccines...

    Authors: Steven Kwasi Korang, Sophie Juul, Emil Eik Nielsen, Joshua Feinberg, Faiza Siddiqui, Giok Ong, Sarah Klingenberg, Areti Angeliki Veroniki, Fanlong Bu, Lehana Thabane, Allan Randrup Thomsen, Janus C. Jakobsen and Christian Gluud
    Citation: Systematic Reviews 2020 9:262
  33. Early identification of patients at risk for postoperative delirium is essential because adequate well-timed interventions could reduce the occurrence of delirium and the related detrimental outcomes.

    Authors: Tayler A. Buchan, Behnam Sadeghirad, Nayeli Schmutz, Nicolai Goettel, Farid Foroutan, Rachel Couban, Lawrence Mbuagbaw and Benjamin T. Dodsworth
    Citation: Systematic Reviews 2020 9:261
  34. Integrated care is a people-centered health delivery approach that ensures the comprehensiveness, quality, and continuity of service across the settings and levels of health systems. The World Health Organizat...

    Authors: Md Zabir Hasan, Shalini Singh, Dinesh Arora, Nishant Jain and Shivam Gupta
    Citation: Systematic Reviews 2020 9:260
  35. Physical activity (PA) is a complex multidimensional human behaviour. Currently, there is no standardised approach for measuring PA using wearable accelerometers in health research. The total volume of PA is a...

    Authors: Tripti Rastogi, Anne Backes, Susanne Schmitz, Guy Fagherazzi, Vincent van Hees and Laurent Malisoux
    Citation: Systematic Reviews 2020 9:259
  36. Previous studies on the impact of corona virus disease 2019 (COVID-19) on the mental health of the patients has been limited by the lack of relevant data. With the rapid and sustained growth of the publication...

    Authors: Jiyuan Shi, Ya Gao, Liang Zhao, Yuanyuan Li, Meili Yan, Ming Ming Niu, Yamin Chen, Ziwei Song, Ruixing Zhang, Lili Zhang and Jinhui Tian
    Citation: Systematic Reviews 2020 9:258
  37. There is a complicated and exploitative history of research with Indigenous peoples and accompanying calls to meaningfully and respectfully include Indigenous knowledge in healthcare. Storytelling approaches t...

    Authors: Kendra L. Rieger, Sarah Gazan, Marlyn Bennett, Mandy Buss, Anna M. Chudyk, Lillian Cook, Sherry Copenace, Cindy Garson, Thomas F. Hack, Bobbie Hornan, Tara Horrill, Mabel Horton, Sandra Howard, Janice Linton, Donna Martin, Kim McPherson…
    Citation: Systematic Reviews 2020 9:257
  38. The COVID-19 pandemic has created a sense of urgency in the research community in their bid to contribute to the evidence required for healthcare policy decisions. With such urgency, researchers experience met...

    Authors: Linda Biesty, Pauline Meskell, Claire Glenton, Hannah Delaney, Mike Smalle, Andrew Booth, Xin Hui S. Chan, Declan Devane and Catherine Houghton
    Citation: Systematic Reviews 2020 9:256
  39. There is limited evidence for the comparative effectiveness of analgesic medicines for adults with low back pain. This systematic review and network meta-analysis aims to determine the analgesic effect, safety...

    Authors: Michael A. Wewege, Matthew K. Bagg, Matthew D. Jones and James H. McAuley
    Citation: Systematic Reviews 2020 9:255
  40. Overviews of reviews (overviews) provide an invaluable resource for healthcare decision-making by combining large volumes of systematic review (SR) data into a single synthesis. The production of high-quality ...

    Authors: Michelle Gates, Allison Gates, Samantha Guitard, Michelle Pollock and Lisa Hartling
    Citation: Systematic Reviews 2020 9:254
  41. Prostate cancer accounts for about 10% of cancers affecting and claiming the lives of men. Studies have reported that women are better than men in recognition of the early manifestations of various cancers. Be...

    Authors: Ebenezer Wiafe, Kofi Boamah Mensah, Adwoa Bemah Boamah Mensah, Varsha Bangalee and Frasia Oosthuizen
    Citation: Systematic Reviews 2020 9:253
  42. Globally, a total of 13.6 million women have died due to maternal causes from 1990 to 2015. Majority of these deaths occurred in resource-limited countries. Among the causes of these deaths, obstructed and pro...

    Authors: Asteray Assmie Ayenew and Biruk Ferede Zewdu
    Citation: Systematic Reviews 2020 9:251
  43. Sickle cell disease (SCD) is an inherited autosomal recessive disorder caused by the replacement of normal haemoglobin (HbA) by mutant Hb (sickle Hb, HbS). The sickle-shaped red blood cells lead to haemolysis ...

    Authors: Britta Runkel, Birgit Klüppelholz, Anne Rummer, Wiebke Sieben, Ulrike Lampert, Claudia Bollig, Martina Markes, Ulrike Paschen and Konstanze Angelescu
    Citation: Systematic Reviews 2020 9:250
  44. Systematic reviews are increasingly prevalent in environmental health due to their ability to synthesize evidence while reducing bias. Different systematic review methods have been developed by the US National...

    Authors: Stephanie M. Eick, Dana E. Goin, Nicholas Chartres, Juleen Lam and Tracey J. Woodruff
    Citation: Systematic Reviews 2020 9:249
  45. Micronutrient deficiency affects the health and development of vulnerable population such as children and pregnant women. Measures such as fortification of food and supplementation have been implemented to pre...

    Authors: Eti Rajwar, Shradha S. Parsekar, Bhumika Tumkur Venkatesh and Zinnia Sharma
    Citation: Systematic Reviews 2020 9:248

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