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Table 1 List of excluded studies along with reasons for exclusion

From: Systematic literature review of pharmacists in general practice in supporting the implementation of shared care agreements in primary care

Number

Authors

Country of origin

Study title

Aim of the study

Reason for exclusion

1

Adams B (2015) [34]

England

NHS Alliance: the evolution of primary care

This paper highlighted the NHS Alliance conference, which focused on pharmacist integration and GP work burden.

C: This was a commentary.

2

Agyapong, V. I., et al. (2011) [35]

Ireland

Shared care between specialized psychiatric services and primary care: the experiences and expectations of consultant psychiatrists in Ireland

The article explores the views of consultant psychiatrists in Ireland on shared care between specialized psychiatric services and primary care for patients with mental health difficulties.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

3

Al-Alawi, K., et al. (2019) [36]

Oman

Care providers’ perceptions towards challenges and opportunities for service improvement at diabetes management clinics in public primary health care in Muscat, Oman: a qualitative study

The article explores the challenges and discusses opportunities for improvement of diabetes management clinics in primary healthcare centres in Oman.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

I: Not a shared care agreement (SCA) intervention.

The study used the wrong model of intervention.

4

Alhabib, S., et al. (2016) [37]

Saudi Arabia

An evolving role of clinical pharmacists in managing diabetes: evidence from the literature

This article is a narrative review of the evidence of the role of clinical pharmacists in managing diabetic patients.

I: Not a shared care agreement (SCA) intervention.

The study used the wrong model of intervention.

5

Ali, S., et al. (2013) [38]

USA

Psychiatric providers’ willingness to participate in shared decision-making (SDM) when prescribing psychotropic medications

This article aims to determine the psychiatric providers’ willingness to engage in SDM and factors that influence willingness.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

I: Not a shared care agreement (SCA) intervention.

The study used the wrong model of intervention.

6

Aljumah, K. and M. A. Hassali (2015) [39]

Saudi Arabia

Impact of pharmacist intervention on adherence and measurable patient outcomes among depressed patients: a randomised controlled study

This article evaluates the effectiveness of shared decision-making on pharmacist intervention for improving adherence and patient outcomes, compared with usual care.

I: Not a shared care agreement (SCA) intervention.

The study used the wrong model of intervention.

C: Wrong design.

The design of the study was not the one desired.

7

Almunef, M., et al. (2019) [40]

England

Management of chronic illness in young people aged 10–24 years: a systematic review to explore the role of primary care pharmacists

The article examines the role of primary care pharmacists in the management of chronic illnesses in young people aged 10–24 years.

I: Insufficient intervention data.

Intervention was not described in enough detail to determine the study should be included.

C: Wrong design.

The design of the study was not the one desired.

8

Alshehri et al. (2021) [41]

England

Evaluating the role and integration of general practice pharmacists in England: a cross-sectional study

The paper aims to assess the role performed by GP pharmacists and their integration into practice exploring facilitators and barriers to integration across England.

I: Insufficient intervention data.

Intervention was not described in enough detail to determine the study should be included.

I: Not a shared care agreement (SCA) intervention.

The study used the wrong model of intervention.

9

Anderson, K., et al. (2015) [42]

Australia

Polypharmacy, deprescribing and shared decision-making in primary care: the role of the accredited pharmacist

Commentary: The article discusses the role of the pharmacist in supporting deprescribing and reducing polypharmacy.

C: This was a commentary.

10

Anonymous (1994) [43]

England

General practitioner/pharmacy interface a local initiative

Commentary: A primary care development officer describes how communication between general practitioners and pharmacists has been improved in Sunderland.

C: This was a commentary.

11

Anonymous (1999) [44]

England

The role of pharmacists in primary care groups (PCGs): a strategic approach

Conference: Examined issues surrounding the relevance and role of pharmacists within the new NHS structures, with a particular emphasis on how pharmacists could contribute to the work of PCGs.

C: This was a commentary.

12

Anonymous (1995) [45]

England

Pharmacy in a new age: the role of government

Commentary: This paper considers important factors shaping the future of pharmacy.

C: This was a commentary.

13

Anonymous (2003) [46]

England

Shared care addiction scheme starts

Commentary: The paper discusses a seamless addiction service involving hospital and community pharmacists.

C: This was a commentary.

14

Ashcroft, D. M., et al. (1998) [47]

England

Shared care: a study of patients’ experiences with erythropoietin

The article evaluates the impact of a shared care scheme on patients receiving erythropoietin treatment.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

15

Bains, S., et al. (2021) [48]

England

The pharmacist-led accelerated transfer of patients to shared care for the monitoring and prescribing of immunomodulatory therapy during COVID-19.

Conference abstract: The conference abstract discusses the use of secondary care pharmacist in supporting transfer of medication into primary care.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

C: Wrong design.

The design of the study was not the one desired.

16

Bajramovic, J., et al. (2004) [49]

Australia

Perceptions around concordance—focus groups and semi-structured interviews conducted with consumers, pharmacists and general practitioners

The article explores the beliefs and expectations of general practitioners, consumers and pharmacists in relation to concordance.

C: Wrong design.

The design of the study was not the one desired.

17

Barnes, E., et al. (2017) [50]

England

New roles for clinical pharmacists in general practice.

Commentary: The paper discusses the NHS England scheme to fund, recruit and employ more clinical pharmacists in GP practices.

C: This was a commentary.

18

Bellingham, C. (2004) [51]

England

How to improve medicines management at the primary/secondary care interface

Commentary: The paper discusses medicines management at the interface.

C: This was a commentary.

19

Berendsen, A. J., et al. (2009) [52]

Netherlands

Transition of care: experiences and preferences of patients across the primary/secondary interface—a qualitative study.

The article explores the transition of care at the primary–secondary interface with reference to the impact of patients’ ability to make choices about their secondary care providers.

I: Not a shared care agreement (SCA) intervention.

The study used the wrong model of intervention.

C: Wrong design.

The design of the study was not the one desired.

20

Bojke, C., et al. (2010) [53]

England

Cost-effectiveness of shared pharmaceutical care for older patients: RESPECT trial findings

The article evaluates the cost-effectiveness of shared pharmaceutical care for older people compared to usual care.

I: Not a shared care agreement (SCA) intervention.

The study used the wrong model of intervention.

C: Wrong design.

The design of the study was not the one desired.

21

British National Association of Health Authorities and Trusts (1994) [54]

England

NAHAT Update: asthma care—the challenge ahead

Commentary: This paper examines the challenges which the treatment and management of asthma for all sectors of the health service.

C: This was a commentary.

22

Cain, R. M. (2006) [55]

USA

The physician-pharmacist interface in the clinical practice of pharmacy

Commentary: This paper deals with healthcare interface and how this may influence the overall practice of clinical pharmacy.

C: This was a commentary.

23

Carrington, I. and J. McAloon (2018) [56]

Northern Ireland

Why shared-care arrangements for prescribing in attention deficit hyperactivity disorder may not be accepted

The article explores the reasons for the failure of uptake of shared-care arrangements for prescribing in attention deficit hyperactivity disorder.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

24

Chana, N., et al. (2017) [57]

England

Improving specialist drug prescribing in primary care using task and error analysis: an observational study

The article explores how clinical decision support systems can support GPs in prescribing specialist drugs using a task and error analysis.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

25

Chartrand, M., et al. (2013) [58]

Canada

Implementation and evaluation of pharmacy services through a practice-based research network (PBRN)

The article discusses how to develop a web-based PBRN and assess the feasibility of this intervention.

I: Not a shared care agreement (SCA) intervention.

The study used the wrong model of intervention.

26

Cox, W. M. (2002) [59]

Wales

Evaluation of a shared-care program for methadone treatment of drug abuse: an international perspective

This article evaluates a North Wales Shared-Care Program for methadone for the treatment of drug abuse.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

I: Not a shared care agreement (SCA) intervention.

The study used the wrong model of intervention.

27

Crowe, S., et al. (2009) [60]

England

The prescribing of specialist medicines: what factors influence GPs’ decision making?

The article explores the factors which influence GPs’ decision-making process when requested to prescribe a specialist drug.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

28

Crowe, S., et al. (2010) [61]

England

Shared care arrangements for specialist drugs in the UK: the challenges facing GP adherence

The article explores the challenges facing GPs’ adherence to shared care arrangements for specialist drugs.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

29

Duggan, C., et al. (2001) [62]

England

Shared care in the UK: failings of the past and lessons for the future

To article explores and evaluates the implementation of shared care in the UK.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

30

Fearne, J., et al. (2018) [63]

Malta

Development and evaluation of shared paediatric pharmaceutical care plan

The article explored the development of a shared paediatric pharmaceutical care template aimed at improving communication between pharmacists across different care settings.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

I: Not a shared care agreement (SCA) intervention.

The study used the wrong model of intervention.

31

Finch, E. and C. Ford (2002) [64]

England

Shared care at the primary and secondary interface: GPs and specialist drug services

Book: This book chapter describes shared care of drug users in the UK.

C: This was a commentary.

32

Grixti, D., et al. (2014) [65]

Malta

Development of shared care guidelines in rheumatology

A poster presentation on the development of shared care guidelines for rheumatology drugs. With the intent of providing seamless care between primary and secondary care settings.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

33

Gu, Y., et al. (2012) [66]

New Zealand

An Innovative Approach to Shared Care–New Zealand Pilot Study of a Technology-enabled National Shared Care Planning Programme

The article describes progress and lessons learned from the New Zealand National Shared Care Planning Programme.

I: Not a shared care agreement (SCA) intervention.

The study used the wrong model of intervention.

34

James, O., et al. (2020) [67]

Ireland

Pharmacists in general practice: a qualitative process evaluation of the General Practice Pharmacist (GPP) study

The article explores the implementation of The General Practice Pharmacist (GPP) intervention and the experiences of study participants and lessons for future implementation.

I: Not a shared care agreement (SCA) intervention.

The study used the wrong model of intervention.

35

Johnson, C. (2018) [68]

USA

Adult attention deficit and hyperactivity disorder (ADHD) clinic: a collaboration between psychiatry, primary care and pharmacy to improve access, care experience and affordability

The article discusses a collaborative, team-based adult ADHD service to improve the care experience.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

36

Jones, B. W. and W. Clark (2003) [69]

England

Shared care agreements: how to overcome the blank page

This article describes how prescribing problems that occur across the primary-secondary care interface are being tackled by pharmacists and others in the West Midlands.

P: Wrong setting.

The research setting was not correct.

C: Wrong design.

The design of the study was not the one desired.

37

Jones, C., et al. (2017) [70]

England

Update on the introduction of dose tapering to modernize and improve the biologics service in a district general hospital

Poster presentation: The poster presentation discusses the introduction of a departmental dose tapering protocol for patients with Rheumatoid arthritis.

P: Wrong setting.

The research setting was not correct.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

38

Jones, E. and O. A. Cuevas (2018) [71]

England

An audit on the use and monitoring of azathioprine (AZA) in a paediatric gastroenterology centre. Could NHS England via specialist commissioning rules (NHS-E-SPR) be affecting quality of care?

Poster presentation: An audit of gastroenterology centre’s adherence to the British Society of Gastroenterology Hepatology and Nutrition (BSPGHAN) guideline.

P: Wrong setting.

The research setting was not correct.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

39

Lloyd, L. A., et al. (2009) [72]

England

An audit of methotrexate monitoring in primary care as part of a shared care agreement

Conference abstract: The conference abstract discusses and audit of methotrexate.

I: Insufficient intervention data.

Intervention was not described in enough detail to determine the study should be included.

40

MacLellan, J., et al. (2017) [73]

England

Shared care: How can we do it? Findings from the British HIV Association (BHIVA) Primary Care Project

Report: Report by BHIVA on Commissioning and delivery of high-quality healthcare for people with HIV between primary and specialist care across the life course.

C: Wwrong design.

The design of the study was not the one desired.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

41

Mercer, K., et al. (2018) [74]

Canada

Physician and pharmacist medication decision-making in the time of electronic health records: mixed-methods study

The article examines how physicians and pharmacists understand and communicate patient-focused medication information using electronic health records.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

C: Wrong design.

The design of the study was not the one desired.

42

Mercer, K., et al. (2020) [75]

Canada

“My pharmacist”: creating and maintaining relationship between physicians and pharmacists in primary care settings

The article examines how pharmacists and primary care physicians communicate with each other and maintain relationships.

C: Wrong design.

The design of the study was not the one desired.

43

Morakinyo, J. (2017) [76]

England

Shared care guideline for the use of methylphenidate, dexamfetamine, lisdexamfetamine dimesylate & atomoxetine for the management of attention deficit hyperactivity disorder (ADHD) in adults (18–64 years).

An NHS document provides information allowing patients with ADHD to be managed safely via the transfer of prescribing across the primary and secondary care interface.

Guideline not original research.

44

Mousa, Y., et al. (2009) [77]

England

Investigating the potential for improved management of patients with long term conditions through shared-care protocols

This article evaluates the need and satisfaction of GPs and community pharmacists within the area with these guidelines.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

45

NICE (2016) [78]

England

Transition between inpatient hospital settings and community or care home settings for adults with social care needs. National Institute for Health and Care Excellence

This guideline covers the transition between inpatient hospital settings and community or care homes for adults with social care needs.

Guideline not original research.

46

Nkansah, N., et al. (2010) [79]

International (Systematic Review: Cochrane Review). Authors based in the USA

Effect of outpatient pharmacists’ non-dispensing roles on patient outcomes and prescribing patterns

The article discusses outpatient pharmacists’ non-dispensing roles on patient and health professional outcomes.

C: Wrong design.

The design of the study was not the one desired.

47

O’Halloran, K. A. (2016) [80]

England

Developing integrated care teams across the North West London System

Conference abstract on developing integrated care system in London.

C: This was a commentary.

48

Petty, D. (2019) [81]

England

Clinical pharmacist roles in primary care networks (PCN)

This article discusses the roles that will be expected of clinical pharmacists within PCNs and how these roles are likely to develop in the future.

C: This was a commentary.

49

Murphy, K (2018) [82]

Australia

Clozapine, concomitant medications and consumers: assessing the accuracy of medication records and the lived experience of people prescribed clozapine under shared care arrangements

This thesis discusses interventions to optimise access to accurate medication information, and communication pathways between stakeholders and consumers of clozapine shared care service.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

50

Richmond, S., et al. (2010) [83]

England

Effectiveness of shared pharmaceutical care for older patients: RESPECT trial findings

The article evaluates the effectiveness of pharmaceutical care for older people, shared between GPs and community pharmacists in the UK, relative to usual care.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

C: Wrong design.

The design of the study was not the one desired.

51

Roberts, R. I. (1997) [84]

Wales

Roberts, R. I. “The Welsh shared care prescribing project”

This article discusses the Welsh shared care prescribing project.

N article not available. The staff performing the systematic review were unable to obtain the full text of the article.

52

Sibbald, B., et al. (1992) [85]

England

Prescribing at the hospital-general practice interface. II: impact of hospital outpatient dispensing policies in England on general practitioners and hospital consultants

This article evaluates the impact on general practitioners and hospital consultants on outpatient dispensing policies.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

53

Shemilt et al. (2021) [86]

England

An evaluation into the refusal of essential shared care agreements: quetiapine

The abstract evaluated the documented reasons for primary care refusal of prescribing quetiapine under ESCAs in one UK NHS Trust.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

C: Wrong design.

The design of the study was not the one desired.

54

Smith, S. M., et al. (2017) [87]

International (Systematic Review: Cochrane Review). Authors based in Republic of Ireland

Shared care across the interface between primary and specialty care in the management of long-term conditions.

This systematic review examines the effectiveness of shared care health service interventions.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

55

Sowerby, C. and D. Taylor (2017) [88]

England

Cross-sector user and provider perceptions on experiences of shared-care clozapine: a qualitative study

This article examines stakeholder perceptions on delivering a shared-care clozapine service and understanding its effectiveness and acceptability of this service.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

56

Steckowych, K. and M. Smith (2018) [89]

USA

Lessons learned and real-world challenges of implementing clinical pharmacy services in a primary care office

Conference abstract on the implementation and challenges faced while starting new clinical pharmacy services within primary care.

C: Wrong design.

The design of the study was not the one desired.

57

Swallow, V. M., et al. (2013) [90]

England

Multidisciplinary teams, and parents, negotiating common ground in shared care of children with long-term conditions: A mixed methods study

This article examines the multi-method study of social interaction between multidisciplinary teams and parents as they shared clinical care.

P: Wrong setting.

The research setting was not correct.

C: Wrong design.

The design of the study was not the one desired.

58

Taylor, D., et al. (2010) [91]

England

User and staff perspectives of clozapine clinic services

The article examines the stakeholder’s perspectives of specialist clozapine clinics in England.

P: Wrong setting.

Something about the research setting was not correct.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

59

Terry, D. R. P. (2011) [92]

England

Medicines management across the primary-hospital healthcare interface: a study of paediatric patients

This thesis examines medicines management across the primary and secondary interface for paediatric patients and how processes can be improved.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

C: Wrong design.

The design of the study was not the one desired.

60

Terry, D., et al. (2012) [93]

England

Prescribing for children at the interfaces of care

This article reviews the current arrangements in England relating to prescribing for children at the interfaces of care.

C: This was a commentary.

61

Travis, S. S. and Bethea L. S. (2001) [94]

USA

Medication administration by family members of dependent elders in shared care arrangements

This article examines family member’s experiences with medication administration.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

C: Wrong design.

The design of the study was not the one desired.

62

Tolley L. et al. (2021) [95]

England

An evaluation into the refusal of essential shared care agreements: aripiprazole

The abstract evaluated the documented reasons for primary care refusal of prescribing aripiprazole under ESCAs in one UK NHS Trust.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

C: Wrong design.

The design of the study was not the one desired.

63

Walker, M. (2001) [96]

England

Shared care for opiate substance misusers in Berkshire

A discussion paper on shared care services for opiate substance misusers.

C: This was a commentary.

64

Yones, E., et al. (2019) [97]

England

Prescribing dronedarone for paroxysmal atrial fibrillation: how is it done across the UK and is it safe?

A short report on the prescribing of dronedarone in the UK and how it can be safely prescribed with a local shared care protocol.

I: Intervention not delivered by a pharmacist in general practice.

The intervention was not delivered by the person specified in the review criteria.

  1. Final Population, Intervention, Comparison, Outcome (PICO)-based taxonomy of reasons used to exclude articles from systematic reviews. N not a PICO-based exclusion reason