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  1. Research

    Conclusions in systematic reviews of mammography for breast cancer screening and associations with review design and author characteristics

    Debates about the benefits and harms of mammography continue despite the accumulation of evidence. We sought to quantify the disagreement across systematic reviews of mammography and determine whether author o...

    Smriti Raichand, Adam G. Dunn, Mei-Sing Ong, Florence T. Bourgeois, Enrico Coiera and Kenneth D. Mandl

    Systematic Reviews 2017 6:105

    Published on: 22 May 2017

  2. Protocol

    Polypharmacy in multimorbid older adults: protocol for a systematic review

    Polypharmacy, the concurrent use of multiple medications, consistently evokes a negative connotation, notably because it is associated with a plethora of adverse events. Nonetheless, the number of individuals ...

    Caroline Sirois, Marie-Laure Laroche, Line Guénette, Edeltraut Kröger, Dan Cooper and Valérie Émond

    Systematic Reviews 2017 6:104

    Published on: 19 May 2017

  3. Protocol

    Comparison of the effect of oral care with four different antiseptics to prevent ventilator-associated pneumonia in adults: protocol for a network meta-analysis

    Ventilator-associated pneumonia (VAP) is defined as the occurrence of pneumonia in patients receiving mechanical ventilation for more than 48 h after endotracheal intubation. The implementation of effective or...

    Zhigang Zhang, Yuying Hou, Jun Zhang, Bo Wang, Juxia Zhang, Ailing Yang, Ge Li and Jinhui Tian

    Systematic Reviews 2017 6:103

    Published on: 19 May 2017

  4. Protocol

    Why are some people more fit than others? Correlates and determinants of cardiorespiratory fitness in adults: protocol for a systematic review

    Cardiorespiratory fitness (CRF) is a physical condition that is now well established as a predictor of numerous adverse health outcomes, independent of physical activity levels. In order to be able to improve ...

    Nita Perumal, Gert B.M. Mensink, Thomas Keil and Jonas David Finger

    Systematic Reviews 2017 6:102

    Published on: 18 May 2017

  5. Research

    An overview of systematic reviews of complementary and alternative therapies for fibromyalgia using both AMSTAR and ROBIS as quality assessment tools

    Fibromyalgia (FM) is a chronic, debilitating pain disorder. Dissatisfaction with conventional medicine can lead people with FM to turn to complementary and alternative medicine (CAM). Two previous overviews of...

    Rachel Perry, Verity Leach, Philippa Davies, Chris Penfold, Andy Ness and Rachel Churchill

    Systematic Reviews 2017 6:97

    Published on: 15 May 2017

  6. Protocol

    Cardioprotective potential of N-acetyl cysteine against hyperglycaemia-induced oxidative damage: a protocol for a systematic review

    Hyperglycaemia-induced oxidative damage is a well-established factor implicated in the development of diabetic cardiomyopathy (DCM) in diabetic individuals. Some of the well-known characteristics of DCM includ...

    Phiwayinkosi V. Dludla, Bongani B. Nkambule, Stephanie C. Dias and Rabia Johnson

    Systematic Reviews 2017 6:96

    Published on: 12 May 2017

  7. Protocol

    The effects of clinical supervision on supervisees and patients in cognitive-behavioral therapy: a study protocol for a systematic review

    Clinical supervision by a senior therapist is a very common practice in psychotherapist training and psychiatric care settings. Though clinical supervision is advocated by most educational and governing instit...

    Sven Alfonsson, Åsa Spännargård, Thomas Parling, Gerhard Andersson and Tobias Lundgren

    Systematic Reviews 2017 6:94

    Published on: 11 May 2017

  8. Protocol

    Protocol of a scoping review on knowledge translation competencies

    Knowledge translation (KT) activities can reduce the gap between “what is known” and “what is done”. Several factors hinder or facilitate KT activities including individual characteristics and organizational a...

    Anastasia A. Mallidou, Pat Atherton, Liza Chan, Noreen Frisch, Stephanie Glegg and Gayle Scarrow

    Systematic Reviews 2017 6:93

    Published on: 2 May 2017

  9. Protocol

    Perioperative adjuvant corticosteroids for post-operative analgesia in elective knee surgery – A systematic review

    Elective knee surgery is performed to reduce chronic pain and improve function in degenerate knees. Treatment of acute post-operative pain is suboptimal in 75% of patients despite multimodal analgesic approach...

    Hasan Raza Mohammad, Marialena Trivella, Thomas W. Hamilton, Louise Strickland, David Murray and Hemant Pandit

    Systematic Reviews 2017 6:92

    Published on: 27 April 2017

  10. Protocol

    MOrtality and infectious complications of therapeutic EndoVAscular interventional radiology: a systematic and meta-analysis protocol

    Endovascular interventional radiology (EIR) is an increasingly popular, mini invasive treatment option for patient with symptomatic vascular disease. The EIR practiced by qualified hands is an effective, well-...

    Kaoutar Mellouk Aid, Hervé Tchala Vignon Zomahoun, Abdelmajid Soulaymani, Karin Lebascle, Stephane Silvera, Pascal Astagneau and Benoit Misset

    Systematic Reviews 2017 6:89

    Published on: 24 April 2017

  11. Protocol

    Protocol: a systematic review of studies developing and/or evaluating search strategies to identify prognosis studies

    Prognosis research is on the rise, its importance recognised because chronic health conditions and diseases are increasingly common and costly. Prognosis systematic reviews are needed to collate and synthesise...

    Nadia Corp, Joanne L. Jordan, Jill A. Hayden, Emma Irvin, Robin Parker, Andrea Smith and Danielle A. van der Windt

    Systematic Reviews 2017 6:88

    Published on: 20 April 2017

  12. Protocol

    Plasma chitotriosidase activity versus CCL18 level for assessing type I Gaucher disease severity: protocol for a systematic review with meta-analysis of individual participant data

    Gaucher disease (GD) is an autosomal recessive lysosomal storage disorder caused by deficiency in acid beta-glucosidase. GD exhibits a wide clinical spectrum of disease severity with an unpredictable natural c...

    Tatiana Raskovalova, Patrick B. Deegan, Ruby Yang, Elena Pavlova, Jérome Stirnemann, José Labarère, Ari Zimran, Pramod K. Mistry and Marc Berger

    Systematic Reviews 2017 6:87

    Published on: 20 April 2017

  13. Systematic review update

    Updated systematic review: associations between proximity to animal feeding operations and health of individuals in nearby communities

    The objective of this review was to update a systematic review of associations between living near an animal feeding operation (AFO) and human health.

    Annette M. O’Connor, Brent W. Auvermann, Rungano S. Dzikamunhenga, Julie M. Glanville, Julian P. T. Higgins, Shelley P. Kirychuk, Jan M. Sargeant, Sarah C. Totton, Hannah Wood and Susanna G. Von Essen

    Systematic Reviews 2017 6:86

    Published on: 18 April 2017

  14. Protocol

    Effectiveness of current policing-related mental health interventions in England and Wales and Crisis Intervention Teams as a future potential model: a systematic review

    Experiencing mental ill health adds a layer of complexity for individuals in touch with the justice system and for those responsible for working in the justice service with these individuals, such as frontline...

    Eddie Kane, Emily Evans and Farhad Shokraneh

    Systematic Reviews 2017 6:85

    Published on: 17 April 2017

  15. Protocol

    Patient- and family-centered performance measures focused on actionable processes of care for persistent and chronic critical illness: protocol for a systematic review

    Approximately 5 to 10% of critically ill patients transition from acute critical illness to a state of persistent and in some cases chronic critical illness. These patients have unique and complex needs that r...

    Louise Rose, Laura Istanboulian, Laura Allum, Lisa Burry, Craig Dale, Nicholas Hart, Claire Kydonaki, Pam Ramsay, Natalie Pattison and Bronwen Connolly

    Systematic Reviews 2017 6:84

    Published on: 17 April 2017

  16. Research

    Determining the gaps between Cochrane reviews and trials of effectiveness of interventions for acute respiratory infections: an audit

    Cochrane primarily aims to systematically review trials of effectiveness that are important to inform clinical decisions. Editorial groups support authors to achieve high-quality reviews and prioritise review ...

    Jasmin Alloo, Sanya Vallath, Chris Del Mar, Matt Carter, Sarah Thorning and Justin Clark

    Systematic Reviews 2017 6:82

    Published on: 13 April 2017

  17. Protocol

    Early identification of patients requiring massive transfusion, embolization, or hemostatic surgery for traumatic hemorrhage: a systematic review protocol

    Hemorrhage is a major cause of early mortality following a traumatic injury. The progression and consequences of significant blood loss occur quickly as death from hemorrhagic shock or exsanguination often occ...

    Alexandre Tran, Maher Matar, Ewout W. Steyerberg, Jacinthe Lampron, Monica Taljaard and Christian Vaillancourt

    Systematic Reviews 2017 6:80

    Published on: 13 April 2017

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