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  1. Protocol

    MOrtality and infectious complications of therapeutic EndoVAscular interventional radiology: a systematic and meta-analysis protocol

    Endovascular interventional radiology (EIR) is an increasingly popular, mini invasive treatment option for patient with symptomatic vascular disease. The EIR practiced by qualified hands is an effective, well-...

    Kaoutar Mellouk Aid, Hervé Tchala Vignon Zomahoun, Abdelmajid Soulaymani, Karin Lebascle, Stephane Silvera, Pascal Astagneau and Benoit Misset

    Systematic Reviews 2017 6:89

    Published on: 24 April 2017

  2. Protocol

    Protocol: a systematic review of studies developing and/or evaluating search strategies to identify prognosis studies

    Prognosis research is on the rise, its importance recognised because chronic health conditions and diseases are increasingly common and costly. Prognosis systematic reviews are needed to collate and synthesise...

    Nadia Corp, Joanne L. Jordan, Jill A. Hayden, Emma Irvin, Robin Parker, Andrea Smith and Danielle A. van der Windt

    Systematic Reviews 2017 6:88

    Published on: 20 April 2017

  3. Protocol

    Plasma chitotriosidase activity versus CCL18 level for assessing type I Gaucher disease severity: protocol for a systematic review with meta-analysis of individual participant data

    Gaucher disease (GD) is an autosomal recessive lysosomal storage disorder caused by deficiency in acid beta-glucosidase. GD exhibits a wide clinical spectrum of disease severity with an unpredictable natural c...

    Tatiana Raskovalova, Patrick B. Deegan, Ruby Yang, Elena Pavlova, Jérome Stirnemann, José Labarère, Ari Zimran, Pramod K. Mistry and Marc Berger

    Systematic Reviews 2017 6:87

    Published on: 20 April 2017

  4. Systematic review update

    Updated systematic review: associations between proximity to animal feeding operations and health of individuals in nearby communities

    The objective of this review was to update a systematic review of associations between living near an animal feeding operation (AFO) and human health.

    Annette M. O’Connor, Brent W. Auvermann, Rungano S. Dzikamunhenga, Julie M. Glanville, Julian P. T. Higgins, Shelley P. Kirychuk, Jan M. Sargeant, Sarah C. Totton, Hannah Wood and Susanna G. Von Essen

    Systematic Reviews 2017 6:86

    Published on: 18 April 2017

  5. Protocol

    Effectiveness of current policing-related mental health interventions in England and Wales and Crisis Intervention Teams as a future potential model: a systematic review

    Experiencing mental ill health adds a layer of complexity for individuals in touch with the justice system and for those responsible for working in the justice service with these individuals, such as frontline...

    Eddie Kane, Emily Evans and Farhad Shokraneh

    Systematic Reviews 2017 6:85

    Published on: 17 April 2017

  6. Protocol

    Patient- and family-centered performance measures focused on actionable processes of care for persistent and chronic critical illness: protocol for a systematic review

    Approximately 5 to 10% of critically ill patients transition from acute critical illness to a state of persistent and in some cases chronic critical illness. These patients have unique and complex needs that r...

    Louise Rose, Laura Istanboulian, Laura Allum, Lisa Burry, Craig Dale, Nicholas Hart, Claire Kydonaki, Pam Ramsay, Natalie Pattison and Bronwen Connolly

    Systematic Reviews 2017 6:84

    Published on: 17 April 2017

  7. Research

    Determining the gaps between Cochrane reviews and trials of effectiveness of interventions for acute respiratory infections: an audit

    Cochrane primarily aims to systematically review trials of effectiveness that are important to inform clinical decisions. Editorial groups support authors to achieve high-quality reviews and prioritise review ...

    Jasmin Alloo, Sanya Vallath, Chris Del Mar, Matt Carter, Sarah Thorning and Justin Clark

    Systematic Reviews 2017 6:82

    Published on: 13 April 2017

  8. Protocol

    Early identification of patients requiring massive transfusion, embolization, or hemostatic surgery for traumatic hemorrhage: a systematic review protocol

    Hemorrhage is a major cause of early mortality following a traumatic injury. The progression and consequences of significant blood loss occur quickly as death from hemorrhagic shock or exsanguination often occ...

    Alexandre Tran, Maher Matar, Ewout W. Steyerberg, Jacinthe Lampron, Monica Taljaard and Christian Vaillancourt

    Systematic Reviews 2017 6:80

    Published on: 13 April 2017

  9. Commentary

    Approaches to interpreting and choosing the best treatments in network meta-analyses

    When randomized trials have addressed multiple interventions for the same health problem, network meta-analyses (NMAs) permit researchers to statistically pool data from individual studies including evidence f...

    L. Mbuagbaw, B. Rochwerg, R. Jaeschke, D. Heels-Andsell, W. Alhazzani, L. Thabane and Gordon H. Guyatt

    Systematic Reviews 2017 6:79

    Published on: 12 April 2017

  10. Protocol

    Therapeutic interventions for alcohol dependence in non-inpatient settings: a systematic review and network meta-analysis (protocol)

    Alcohol dependence is common and serious cause of social and physical harm. However, the optimal management of those with moderate and severe alcohol dependence in primary and community care after detoxificati...

    Hung-Yuan Cheng, Roy G. Elbers, Julian P. T. Higgins, Abigail Taylor, Georgina J. MacArthur, Luke McGuinness, Sarah Dawson, José A. López-López, Sean Cowlishaw, Matthew Hickman and David Kessler

    Systematic Reviews 2017 6:77

    Published on: 11 April 2017

  11. Protocol

    Inter-pregnancy interval and pregnancy outcomes among women with delayed childbearing: protocol for a systematic review

    Women in high resource nations are increasingly delaying childbearing until their thirties. Delayed childbearing poses challenges for the spacing of a woman’s pregnancies. Inter-pregnancy intervals <12 months ...

    Mani Asgharpour, Sofia Villarreal, Laura Schummers, Jennifer Hutcheon, Dorothy Shaw and Wendy V. Norman

    Systematic Reviews 2017 6:75

    Published on: 8 April 2017

  12. Protocol

    Epidemiology and reporting characteristics of overviews of reviews of healthcare interventions published 2012–2016: protocol for a systematic review

    Overviews of systematic reviews (overviews) attempt to systematically retrieve and summarize the results of multiple systematic reviews (SRs) for a given condition or public health problem. Two prior descripti...

    Dawid Pieper, Michelle Pollock, Ricardo M. Fernandes, Roland Brian Büchter and Lisa Hartling

    Systematic Reviews 2017 6:73

    Published on: 7 April 2017

  13. Protocol

    Digoxin versus placebo, no intervention, or other medical interventions for atrial fibrillation and atrial flutter: a protocol for a systematic review with meta-analysis and Trial Sequential Analysis

    Atrial fibrillation is the most common arrhythmia of the heart with a prevalence of approximately 2% in the western world. Atrial flutter, another arrhythmia, occurs less often with an incidence of approximate...

    Naqash J. Sethi, Sanam Safi, Joshua Feinberg, Emil E. Nielsen, Christian Gluud and Janus C. Jakobsen

    Systematic Reviews 2017 6:71

    Published on: 5 April 2017

  14. Protocol

    Cancer and central nervous system disorders: protocol for an umbrella review of systematic reviews and updated meta-analyses of observational studies

    The objective of this study will be to synthesize the epidemiological evidence and evaluate the validity of the associations between central nervous system disorders and the risk of developing or dying from ca...

    Ferrán Catalá-López, Brian Hutton, Jane A. Driver, Matthew J. Page, Manuel Ridao, José M. Valderas, Adolfo Alonso-Arroyo, Jaume Forés-Martos, Salvador Martínez, Ricard Gènova-Maleras, Diego Macías-Saint-Gerons, Benedicto Crespo-Facorro, Eduard Vieta, Alfonso Valencia and Rafael Tabarés-Seisdedos

    Systematic Reviews 2017 6:69

    Published on: 4 April 2017

  15. Protocol

    Epidemiology of chronic obstructive pulmonary disease in the global HIV-infected population: a systematic review and meta-analysis protocol

    Evidence suggests a relationship between human immunodeficiency virus (HIV) infection and chronic obstructive pulmonary disease (COPD). Although the high burden of COPD and the HIV disease is clearly demonstra...

    Jean Joel R. Bigna, Angeladine Malaha Kenne and Serra Lem Asangbeh

    Systematic Reviews 2017 6:68

    Published on: 29 March 2017

  16. Protocol

    Variables associated with unplanned general adult ICU admission in hospitalised patients: protocol for a systematic review

    Failure to promptly identify deterioration in hospitalised patients is associated with delayed admission to intensive care units (ICUs) and poor outcomes. Existing vital sign-based Early Warning Score (EWS) al...

    James Malycha, Tim Bonnici, Katarina Sebekova, Tatjana Petrinic, Duncan Young and Peter Watkinson

    Systematic Reviews 2017 6:67

    Published on: 28 March 2017

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