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Systematic Reviews

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  1. Content type: Research

    Understanding how physical activity (PA) influences cognitive function in populations with cognitive impairments, such as dementia, is an increasingly studied topic yielding numerous published systematic revie...

    Authors: Azeem Rathore and Barbara Lom

    Citation: Systematic Reviews 2017 6:124

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  2. Content type: Protocol

    Multiple reviews demonstrated high variability in effectiveness and cost-effectiveness outcomes among studies on breast cancer screening (BCS) programmes. No study to our knowledge has summarized the current e...

    Authors: O. Mandrik, O. I. Ekwunife, N. Zielonke, F. Meheus, J. L. Severens, S. K. Lhachimi and R. Murillo

    Citation: Systematic Reviews 2017 6:122

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  3. Content type: Protocol

    Anxiety and depression are common in young people and are associated with a range of adverse outcomes. Research has suggested a relationship between emotional disorder and poor school attendance, and thus poor...

    Authors: Katie Finning, Darren Moore, Obioha C. Ukoumunne, Emilia Danielsson-Waters and Tamsin Ford

    Citation: Systematic Reviews 2017 6:121

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  4. Content type: Protocol

    Cellular-based therapies represent a platform technology within the rapidly expanding field of regenerative medicine and are distinct from conventional therapeutics—offering a unique approach to managing what ...

    Authors: David Pettitt, Zeeshaan Arshad, Benjamin Davies, James Smith, Anna French, Doug Cole, Kim Bure, Sue Dopson, David DiGiusto, Jeff Karp, Brock Reeve, Richard Barker, Georg Holländer and David Brindley

    Citation: Systematic Reviews 2017 6:120

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  5. Content type: Protocol

    Stress ulcer prophylaxis is considered standard of care in many critically ill patients in the intensive care unit (ICU). However, the quality of evidence supporting this has recently been questioned, and clin...

    Authors: Søren Marker, Anders Perner, Jørn Wetterslev, Marija Barbateskovic, Janus Christian Jakobsen, Mette Krag, Anders Granholm, Carl Thomas Anthon and Morten Hylander Møller

    Citation: Systematic Reviews 2017 6:118

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  6. Content type: Protocol

    Network meta-analysis, a method to synthesise evidence from multiple treatments, has increased in popularity in the past decade. Two broad approaches are available to synthesise data across networks, namely, a...

    Authors: Amalia (Emily) Karahalios, Georgia Salanti, Simon L. Turner, G. Peter Herbison, Ian R. White, Areti Angeliki Veroniki, Adriani Nikolakopoulou and Joanne E. Mckenzie

    Citation: Systematic Reviews 2017 6:119

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  7. Content type: Research

    The methodological quality and completeness of reporting of the systematic reviews (SRs) is fundamental to optimal implementation of evidence-based health care and the reduction of research waste. Methods exis...

    Authors: Kusala Pussegoda, Lucy Turner, Chantelle Garritty, Alain Mayhew, Becky Skidmore, Adrienne Stevens, Isabelle Boutron, Rafael Sarkis-Onofre, Lise M. Bjerre, Asbjørn Hróbjartsson, Douglas G. Altman and David Moher

    Citation: Systematic Reviews 2017 6:117

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  8. Content type: Protocol

    Preliminary evidence suggests statins may reduce major perioperative vascular events. However, evidence is limited to observational studies, underpowered trials, and non-comprehensive systematic reviews. This ...

    Authors: Erica Aranha Suzumura, Rodrigo Antonini Ribeiro, Leticia Kawano-Dourado, Pedro Gabriel de Barros e Silva, Claudia Oliveira, Mabel Fernandes Figueiró, Alexandre Biasi Cavalcanti, Renato D. Lopes and Otavio Berwanger

    Citation: Systematic Reviews 2017 6:116

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  9. Content type: Protocol

    The practicality of applying evidence to healthcare systems with the aim of implementing change is an ongoing challenge for practitioners, policy makers, and academics. Shared decision- making (SDM), a method ...

    Authors: Gary Groot, Tamara Waldron, Tracey Carr, Linda McMullen, Lori-Ann Bandura, Shelley-May Neufeld and Vicky Duncan

    Citation: Systematic Reviews 2017 6:114

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  10. Content type: Protocol

    Evidence highlights a high prevalence of common mental health disorders in armed forces veterans and their families, with depression, anxiety, alcohol misuse and anger being more common than PTSD. This paper p...

    Authors: Luke O’Shea, Ed Watkins and Paul Farrand

    Citation: Systematic Reviews 2017 6:112

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  11. Content type: Protocol

    Hemodynamic instability during renal replacement therapy (HIRRT) in the form of intradialytic hypotension (IDH) is a frequent complication of hemodialysis in end-stage kidney disease (ESKD), and most studies h...

    Authors: Adrianna Douvris, Swapnil Hiremath, Lauralyn McIntyre, Lindsey Sikora, Catherine Weber and Edward G. Clark

    Citation: Systematic Reviews 2017 6:113

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  12. Content type: Protocol

    There exist many evidence-based interventions available to manage procedural pain in children and neonates, yet they are severely underutilized. Parents play an important role in the management of their child’...

    Authors: Allison Gates, Kassi Shave, Robin Featherstone, Kelli Buckreus, Samina Ali, Shannon Scott and Lisa Hartling

    Citation: Systematic Reviews 2017 6:109

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  13. Content type: Protocol

    The use of fat grafting as a reconstructive surgical option is becoming much more common. Adipose-derived stem cells found in fat grafts are believed to facilitate wound healing via differentiation into fibrob...

    Authors: Oliver J. Smith, Muholan Kanapathy, Ankur Khajuria, Max Prokopenko, Nadine Hachach-Haram, Haroon Mann and Ash Mosahebi

    Citation: Systematic Reviews 2017 6:111

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  14. Content type: Research

    It is not known, whether outcome reporting in trials of total joint arthroplasty in the recent years is adequate or not. Our objective was to assess whether outcomes reported in total joint replacement (TJR) t...

    Authors: Peter D. H. Wall, Bethan L. Richards, Andrew Sprowson, Rachelle Buchbinder and Jasvinder A. Singh

    Citation: Systematic Reviews 2017 6:106

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  15. Content type: Protocol

    Achilles tendinopathy is one of the most common overuse injuries in recreational and competitive runners, yet the clinical significance and frequency of abnormal sonographic characteristics in runners remains ...

    Authors: Prue Molyneux, Matthew Carroll, Sarah Stewart, Angela Brenton-Rule and Keith Rome

    Citation: Systematic Reviews 2017 6:108

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  16. Content type: Research

    Debates about the benefits and harms of mammography continue despite the accumulation of evidence. We sought to quantify the disagreement across systematic reviews of mammography and determine whether author o...

    Authors: Smriti Raichand, Adam G. Dunn, Mei-Sing Ong, Florence T. Bourgeois, Enrico Coiera and Kenneth D. Mandl

    Citation: Systematic Reviews 2017 6:105

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  17. Content type: Protocol

    Ventilator-associated pneumonia (VAP) is defined as the occurrence of pneumonia in patients receiving mechanical ventilation for more than 48 h after endotracheal intubation. The implementation of effective or...

    Authors: Zhigang Zhang, Yuying Hou, Jun Zhang, Bo Wang, Juxia Zhang, Ailing Yang, Ge Li and Jinhui Tian

    Citation: Systematic Reviews 2017 6:103

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  18. Content type: Protocol

    Polypharmacy, the concurrent use of multiple medications, consistently evokes a negative connotation, notably because it is associated with a plethora of adverse events. Nonetheless, the number of individuals ...

    Authors: Caroline Sirois, Marie-Laure Laroche, Line Guénette, Edeltraut Kröger, Dan Cooper and Valérie Émond

    Citation: Systematic Reviews 2017 6:104

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  19. Content type: Protocol

    Diabetic foot disease is associated with major morbidity, mortality, costs, and reduction of a person’s quality of life. Investigating the epidemiology of diabetic foot disease is the backbone of diabetic foot...

    Authors: Jaap J. van Netten, Mendel Baba and Peter A. Lazzarini

    Citation: Systematic Reviews 2017 6:101

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  20. Content type: Protocol

    Cardiorespiratory fitness (CRF) is a physical condition that is now well established as a predictor of numerous adverse health outcomes, independent of physical activity levels. In order to be able to improve ...

    Authors: Nita Perumal, Gert B.M. Mensink, Thomas Keil and Jonas David Finger

    Citation: Systematic Reviews 2017 6:102

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  21. Content type: Protocol

    With an ageing population and increasing numbers of people with life-limiting illness, there is a growing demand for palliative day services. There is a need to measure and demonstrate the quality of these ser...

    Authors: Seán R. O’Connor, Martin Dempster and Noleen K. McCorry

    Citation: Systematic Reviews 2017 6:100

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