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  1. Eczema is a common chronic or chronically relapsing, inflammatory skin disease that exerts a substantial negative impact on quality of life (QoL). The Harmonising Outcome Measures for Eczema (HOME) initiative ...

    Authors: Daniel Heinl, Cecilia A. C. Prinsen, Aaron M. Drucker, Robert Ofenloch, Rosemary Humphreys, Tracey Sach, Carsten Flohr and Christian Apfelbacher
    Citation: Systematic Reviews 2016 5:25
  2. The length of postnatal hospital stay has declined over the last 40 years. There is little evidence to support a policy of early discharge following birth, and there is some concern about whether early dischar...

    Authors: Eleanor Jones, Beck Taylor, Christine MacArthur, Ruth Pritchett and Carole Cummins
    Citation: Systematic Reviews 2016 5:24
  3. Of the over 1 million reported cases of traumatic brain injuries reported annually in the USA, a sizeable proportion are characterized as mild. Although it is generally well-accepted that most people who suffe...

    Authors: Chris Lepage, Tina Yuan, Stephanie Leon, Shawn Marshall, Patrick Labelle and Mark Ferland
    Citation: Systematic Reviews 2016 5:23
  4. Most orthodontic treatment plans need some form of anchorage to control the reciprocal forces of tooth movement. Orthodontic mini implants (OMIs) have been hailed for having revolutionized orthodontics, becaus...

    Authors: Reint Meursinge Reynders, Laura Ronchi, Luisa Ladu, Nicola Di Girolamo, Jan de Lange, Nia Roberts and Sharon Mickan
    Citation: Systematic Reviews 2016 5:22
  5. The prevalence of paternal depression in the postnatal period is estimated to be approximately 10 %. Effective partner education during pregnancy has the possibility to prevent postnatal mental health problems...

    Authors: Maiko Suto, Kenji Takehara, Yumina Yamane and Erika Ota
    Citation: Systematic Reviews 2016 5:21
  6. The lack of evidence of the role of workplaces as settings for behaviour change delivery and the failure to recognise and address the complexity of the work environment has been acknowledged. This systematic r...

    Authors: Sarah A. Smith, Amelia A. Lake, Carolyn Summerbell, Vera Araujo-Soares and Frances Hillier-Brown
    Citation: Systematic Reviews 2016 5:20
  7. Prosthetic hip implants have many combinations of bearing surface materials, sizes, and fixation techniques, which can determine the quality of life of patients after primary total hip replacement (THR) and th...

    Authors: Elsa M. R. Marques, Rachel Humphriss, Nicky J. Welton, Julian P. T. Higgins, William Hollingworth, Jose A. Lopez-Lopez, Howard Thom, Linda P. Hunt, Ashley W. Blom and Andrew D. Beswick
    Citation: Systematic Reviews 2016 5:19
  8. Steroids are often combined with local anesthetic (LA) and injected to reduce pain associated with various chronic non-cancer pain (CNCP) complaints. The biological rationale behind injection of a steroid solu...

    Authors: Harsha Shanthanna, Jason W. Busse, Lehana Thabane, James Paul, Rachel Couban, Harman Choudhary, Alka Kaushal, Erica Suzumura, Isabel Kim and Prathiba Harsha
    Citation: Systematic Reviews 2016 5:18
  9. Periodontal disease is an inflammatory disease of the tissues supporting the teeth. Women who have periodontal disease while pregnant may be at risk of adverse pregnancy outcomes. Although the association betw...

    Authors: Sizzle F. Vanterpool, Kathleen Tomsin, Leticia Reyes, Luc J. Zimmermann, Boris W. Kramer and Jasper V. Been
    Citation: Systematic Reviews 2016 5:16
  10. The association between low socioeconomic status (SES) and poor health is well documented in the existing literature. Nonetheless, evidence on the relationship between SES and gastrointestinal (GI) infections ...

    Authors: Tanith C. Rose, Natalie Adams, David C. Taylor-Robinson, Benjamin Barr, Jeremy Hawker, Sarah O’Brien, Mara Violato and Margaret Whitehead
    Citation: Systematic Reviews 2016 5:13
  11. Elevated levels of risky alcohol consumption and alcohol-related harm have been reported for sportspeople and supporters compared to non-sporting populations. Limited systematic reviews have been conducted to ...

    Authors: Melanie Kingsland, John H. Wiggers, Khanrin P. Vashum, Rebecca K. Hodder and Luke Wolfenden
    Citation: Systematic Reviews 2016 5:12
  12. Acute diarrhea and acute gastroenteritis (AD/AGE) are common among children in low- and middle-income countries (LMIC) and high-income countries (HIC). Supportive therapy including maintaining feeding, prevent...

    Authors: Ivan D. Florez, Reem Al-Khalifah, Javier M. Sierra, Claudia M. Granados, Juan J. Yepes-Nuñez, Carlos Cuello-Garcia, Giordano Perez-Gaxiola, Adriana M. Zea, Gilma N. Hernandez, Areti-Angeliki Veroniki, Gordon H. Guyatt and Lehana Thabane
    Citation: Systematic Reviews 2016 5:14
  13. Systematic reviews seek to bring together research evidence to answer the question for the review. The reviewers usually wish to compare, contrast and, if appropriate, combine the findings of the existing rese...

    Authors: Mike Clarke and Paula R. Williamson
    Citation: Systematic Reviews 2016 5:11
  14. Traumatic brain injury (TBI) is a devastating condition with significant long-term mortality and morbidity. Despite current need for objective indicators to guide initial decision-making, few reliable acute ph...

    Authors: Hourmazd Haghbayan, Amélie Boutin, Mathieu Laflamme, François Lauzier, Michèle Shemilt, Lynne Moore, Ryan Zarychanski, Dean Fergusson and Alexis F. Turgeon
    Citation: Systematic Reviews 2016 5:10
  15. Overweight and obesity in children and adults is a major public health concern. Emerging evidence suggests dietary sodium intake may be associated with obesity. This systematic review and meta-analysis will ai...

    Authors: Carley A. Grimes, Dieuwerke P. Bolhuis, Feng J. He and Caryl A. Nowson
    Citation: Systematic Reviews 2016 5:7
  16. Cost-effectiveness analysis has been recognized as an important tool to determine the efficiency of healthcare interventions and services. There is a need for evaluating the reporting of methods and results of...

    Authors: Ferrán Catalá-López, Manuel Ridao, Adolfo Alonso-Arroyo, Anna García-Altés, Chris Cameron, Diana González-Bermejo, Rafael Aleixandre-Benavent, Enrique Bernal-Delgado, Salvador Peiró, Rafael Tabarés-Seisdedos and Brian Hutton
    Citation: Systematic Reviews 2016 5:6
  17. Worldwide, the prevalences of diabetes and dementia are both increasing, particularly in older people. Rates of diabetes in people with dementia are between 13 and 20 %. Diabetes management and diabetic self-c...

    Authors: Frances Bunn, Claire Goodman, Jo Rycroft Malone, Peter Reece Jones, Chris Burton, Greta Rait, Daksha Trivedi, Antony Bayer and Alan Sinclair
    Citation: Systematic Reviews 2016 5:5
  18. Overviews of systematic reviews attempt to systematically retrieve and summarise the results of multiple systematic reviews into a single document. Methods for conducting, interpreting and reporting overviews ...

    Authors: Carole Lunny, Sue E. Brennan, Steve McDonald and Joanne E. McKenzie
    Citation: Systematic Reviews 2016 5:4
  19. Chronic kidney disease-mineral and bone disorders (CKD-MBD) have been associated with poor health outcomes, including diminished quality and length of life. Standard management for CKD-MBD includes phosphate-r...

    Authors: Nigar Sekercioglu, Jason W. Busse, Reem A. Mustafa, Gordon H. Guyatt and Lehana Thabane
    Citation: Systematic Reviews 2016 5:2
  20. Research with a focus on Aboriginal and Torres Strait Islander Australian’s (hereafter referred to as Indigenous1) needs is crucial to ensure culturally appropriate evidence-based strategies are developed to impr...

    Authors: Sara Farnbach, Anne-Marie Eades and Maree Lisa Hackett
    Citation: Systematic Reviews 2015 4:189
  21. Up to 90 % of people with scleroderma have gastrointestinal (GI) problems such as constipation, bloating, diarrhea, and malabsorption. These problems significantly impair quality of life. Our objective was to ...

    Authors: Brian Younho Hong, Raymond Giang, Lawrence Mbuagbaw, Maggie Larche and Lehana Thabane
    Citation: Systematic Reviews 2015 4:188
  22. Suicidal behaviour is a complex phenomenon with a multitude of risk factors. Brain-derived neurotrophic factor (BDNF), a protein crucial to nervous system function, may be involved in suicide risk. The objecti...

    Authors: Rebecca B. Eisen, Stefan Perera, Laura Banfield, Rebecca Anglin, Luciano Minuzzi and Zainab Samaan
    Citation: Systematic Reviews 2015 4:187
  23. The mental health of children and adolescents is a key area of health concern internationally. Previous empirical studies suggest that resilience may act as a protective mechanism towards the development of me...

    Authors: Julia Dray, Jenny Bowman, Luke Wolfenden, Elizabeth Campbell, Megan Freund, Rebecca Hodder and John Wiggers
    Citation: Systematic Reviews 2015 4:186
  24. The long-term management of chronic diseases requires adoption of complex dietary recommendations, which can be facilitated by regular coaching to support sustained behaviour change. Telehealth interventions c...

    Authors: Jaimon T. Kelly, Dianne P. Reidlinger, Tammy C. Hoffmann and Katrina L. Campbell
    Citation: Systematic Reviews 2015 4:185
  25. Tobacco and alcohol are recognised as the major risk factors for both oral cavity (mouth) and oropharyngeal (throat) cancers, with increasing acceptance of the role of human papillomavirus (HPV) in the aetiolo...

    Authors: Sweta Mathur, David I. Conway, Heather Worlledge-Andrew, Lorna M.D. Macpherson and Alastair J. Ross
    Citation: Systematic Reviews 2015 4:184
  26. Testicular cancer is primarily treated with the surgical removal of the affected testis. About 50 % of testicular cancer patients present with a stage I seminoma. If no chemo- or radiotherapy as adjuvant treat...

    Authors: Frank Kunath, Annabel Spek, Katrin Jensen, Friedemann Zengerling and Stefanie Schmidt
    Citation: Systematic Reviews 2015 4:182
  27. Improving health-care outcomes for people living with dementia when they are admitted to hospital is a policy priority. Dementia friendly interventions in health care promote inclusion of patients and carers i...

    Authors: Melanie Handley, Frances Bunn and Claire Goodman
    Citation: Systematic Reviews 2015 4:180
  28. Whilst nutrition is vital to survival in health, the precise role of nutrition during critical illness is controversial. More specifically, the exact amount of energy that is required during critical illness t...

    Authors: Emma J. Ridley, Andrew R. Davies, Carol Hodgson, Adam Deane, Michael Bailey and D. James Cooper
    Citation: Systematic Reviews 2015 4:179
  29. A physically active lifestyle plays a preventative role in the development of various chronic diseases and mental health conditions. Unfortunately, few adults achieve the minimum amount of physical activity an...

    Authors: Christina C. Loitz, Robert J. Potter, Jessica L. Walker, Nicole C. McLeod and Nora J. Johnston
    Citation: Systematic Reviews 2015 4:178
  30. The risk of developing cardiovascular disease is directly correlated to one’s resting blood pressure (BP), age, and biological sex. Resting BP can be reduced using handgrip exercise training, but the impact of...

    Authors: Danielle C. Bentley, Cindy H. Nguyen and Scott G. Thomas
    Citation: Systematic Reviews 2015 4:176
  31. Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder. While abdominal pain is a dominant symptom of IBS, many sufferers also report widespread hypersensitivity and present with other...

    Authors: Rosemary J. Chakiath, Philip J. Siddall, John E. Kellow, Julia M. Hush, Mike P. Jones, Anna Marcuzzi and Paul J. Wrigley
    Citation: Systematic Reviews 2015 4:175
  32. Fatigue is a common symptom in cancer patients that can persist beyond the curative treatment phase. Some evidence has been reported for interventions for fatigue during active treatment. However, to date, the...

    Authors: Teresa Corbett, Declan Devane, Jane C. Walsh, AnnMarie Groarke and Brian E. McGuire
    Citation: Systematic Reviews 2015 4:174
  33. Helping people make well-informed decisions about dysvascular partial foot amputation is becoming increasingly important as improvements in diabetes care and vascular surgery make more distal amputations incre...

    Authors: Michael P Dillon, Stefania Fatone and Matthew Quigley
    Citation: Systematic Reviews 2015 4:173

    The Erratum to this article has been published in Systematic Reviews 2016 5:1

  34. The recent Ebola epidemic in western Africa developed into an acute public health emergency of unprecedented level in modern times. The treatment provided in most cases has been limited to supportive care, as ...

    Authors: Hussein Sweiti, Obinna Ekwunife, Thomas Jaschinski and Stefan K. Lhachimi
    Citation: Systematic Reviews 2015 4:171
  35. Probiotics may prevent antibiotic-associated and Clostridium difficile-associated diarrhoea (AAD/CDAD). Many spinal cord injury centre (SCIC) practitioners consider probiotics generically and may not realise that...

    Authors: Samford Wong, Ali Jamous, Jean O’Driscoll, Ravi Sekhar, Mofid Saif, Steve O’Driscoll, Sarah Lewis, Eamonn McKeown and Shashi P. Hirani
    Citation: Systematic Reviews 2015 4:170
  36. The objective of the study is to conduct a systematic review to compare the effects of high-dose chemotherapy (HDCT) with autologous haematopoietic stem cell transplantation (HSCT) versus standard-dose chemoth...

    Authors: Caroline Main, Jayne S. Wilson, Simon P. Stevens, Aimee E. Houlton, Martin English, Pamela R. Kearns, Bob Phillips, Barry Pizer, Sophie Wilne and Keith Wheatley
    Citation: Systematic Reviews 2015 4:168
  37. Transplantation improves survival and the quality of life of patients with end-stage organ failure. Infection, due to surgical issues, host factors such as diabetes, immunosuppression, and hypogammaglobulinemi...

    Authors: Juthaporn Cowan, Brian Hutton, Nicholas Fergusson, Alexandria Bennett, Jason Tay, D. William Cameron and Greg A. Knoll
    Citation: Systematic Reviews 2015 4:167
  38. Several options are available for the treatment of chronic rhinosinusitis (CRS), but disease control remains elusive for many patients. Recently, literature has emerged describing anti-IgE monoclonal antibody ...

    Authors: Chris J. Hong, Adrian C. Tsang, Jason G. Quinn, James P. Bonaparte, Adrienne Stevens and Shaun J. Kilty
    Citation: Systematic Reviews 2015 4:166
  39. Head injury represents an extremely common presentation to emergency departments (ED), but not all patients present immediately after injury. There is evidence that clinical deterioration following head injury...

    Authors: Carl Marincowitz, Christopher M. Smith and William Townend
    Citation: Systematic Reviews 2015 4:165

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