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  1. There is currently no mechanism in place outside of government to provide rapid syntheses of the best available research evidence about problems, options and/or implementation considerations related to a speci...

    Authors: Michael G Wilson, John N Lavis and Francois-Pierre Gauvin
    Citation: Systematic Reviews 2015 4:25
  2. Indoor air pollution (IAP) interventions are widely promoted as a means of reducing indoor air pollution/health from solid fuel use; and research addressing impact of these interventions has increased substant...

    Authors: Reginald Quansah, Caroline A Ochieng, Sean Semple, Sanjar Juvekar, Jacques Emina, Frederick Ato Armah and Isaac Luginaah
    Citation: Systematic Reviews 2015 4:22
  3. Vortioxetine is the first mixed serotonin agonist and antagonist antidepressant approved in the US. We sought to evaluate all published and unpublished data available to determine the efficacy and harms of vor...

    Authors: Amanda S Meeker, Megan C Herink, Dean G Haxby and Daniel M Hartung
    Citation: Systematic Reviews 2015 4:21
  4. The aims of antenatal education are broad and encompass outcomes related to pregnancy, birth, and parenthood. Both form and content of antenatal education have changed over time without evidence of effects on ...

    Authors: Carina Sjöberg Brixval, Solveig Forberg Axelsen, Stine Glenstrup Lauemøller, Stig Krøger Andersen, Pernille Due and Vibeke Koushede
    Citation: Systematic Reviews 2015 4:20
  5. Attention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders of children and adolescents, with a significant impact on health services and the community in terms of ec...

    Authors: Ferrán Catalá-López, Brian Hutton, Amparo Núñez-Beltrán, Alain D Mayhew, Matthew J Page, Manuel Ridao, Aurelio Tobías, Miguel A Catalá, Rafael Tabarés-Seisdedos and David Moher
    Citation: Systematic Reviews 2015 4:19
  6. The prevalence of vitamin D deficiency in hemodialysis patients is high. While most hemodialysis patients are treated with activated vitamin D (1,25[OH]2D) to prevent renal osteodystrophy, clinical practices of t...

    Authors: Anita Mehrotra, Wai-Yin Leung and Tannia Joson
    Citation: Systematic Reviews 2015 4:115

    The Erratum to this article has been published in Systematic Reviews 2015 4:106

  7. A peer-reviewed journal would not survive without the generous time and insightful comments of the reviewers, whose efforts often go unrecognized. Although final decisions are always editorial, they are greatl...

    Authors: David Moher, Paul Shekelle and Lesley A Stewart
    Citation: Systematic Reviews 2015 4:94

    The Erratum to this article has been published in Systematic Reviews 2015 4:100

  8. Worldwide, approximately 12% of children under the age of 5 are either overweight or obese. As many young children spend 30 h or more per week in childcare centres with childcare educators. Targeting childcare...

    Authors: Stéphanie Ward, Mathieu Bélanger, Denise Donovan, Amanda Horsman and Natalie Carrier
    Citation: Systematic Reviews 2015 4:18
  9. Sugar-sweetened beverages (SSBs) have been stressed as relevant targets of public health interventions considering the negative outcomes derived from their excessive intake. Though the evidence from published ...

    Authors: Elisa J Vargas-Garcia, Charlotte EL Evans and Janet E Cade
    Citation: Systematic Reviews 2015 4:17
  10. Mentorship is perceived as vital to attracting, training, and retaining nursing faculty members and to maintaining high-quality education programs. While there is emerging evidence to support the value of ment...

    Authors: Lorelli Nowell, Deborah E White, Kelly Mrklas and Jill M Norris
    Citation: Systematic Reviews 2015 4:16
  11. People with diabetic retinopathy tend to have lower levels of health-related quality of life than individuals with no retinopathy. Strategies for screening and treatment have been shown to be cost-effective. I...

    Authors: Christopher J Sampson, Jonathan C Tosh, Christopher P Cheyne, Deborah Broadbent and Marilyn James
    Citation: Systematic Reviews 2015 4:15
  12. Canada’s diverse society and its statutory commitment to multiculturalism means that a synthesis of knowledge related to the healthcare experiences of immigrants is essential to realise the health potential fo...

    Authors: Gina MA Higginbottom, Myfanwy Morgan, Mirande Alexandre, Yvonne Chiu, Joan Forgeron, Deb Kocay and Rubina Barolia
    Citation: Systematic Reviews 2015 4:13
  13. Primary studies examining the accuracy of a continuous test evaluate its sensitivity and specificity at one or more thresholds. Meta-analysts then usually perform a separate meta-analysis for each threshold. H...

    Authors: Richard D Riley, Ikhlaaq Ahmed, Joie Ensor, Yemisi Takwoingi, Amanda Kirkham, R Katie Morris, J Pieter Noordzij and Jonathan J Deeks
    Citation: Systematic Reviews 2015 4:12
  14. Providing patient-centered care requires that patients partner in their personal health-care decisions to the full extent desired. Patient decision aids facilitate processes of shared decision-making between p...

    Authors: Holly O Witteman, Selma Chipenda Dansokho, Heather Colquhoun, Angela Coulter, Michèle Dugas, Angela Fagerlin, Anik MC Giguere, Sholom Glouberman, Lynne Haslett, Aubri Hoffman, Noah Ivers, France Légaré, Jean Légaré, Carrie Levin, Karli Lopez, Victor M Montori…
    Citation: Systematic Reviews 2015 4:11
  15. Strawberry diseases are a major limiting factor that severely impact plant agronomic performance. Regarding limitations of traditional techniques for detection of pathogens, researchers have developed specific...

    Authors: Seyed Mahyar Mirmajlessi, Marialaura Destefanis, Richard Alexander Gottsberger, Marika Mänd and Evelin Loit
    Citation: Systematic Reviews 2015 4:9
  16. Despite criticism, quality improvement (QI) continues to drive political and educational priorities within health care. Until recently, QI educational interventions have varied, targeting mainly postgraduates,...

    Authors: Lorraine Armstrong, William Lauder and Ashley Shepherd
    Citation: Systematic Reviews 2015 4:8
  17. The aim of this rapid knowledge synthesis was to provide relevant research evidence to inform the implementation of a new health service in Nova Scotia, Canada: Collaborative Emergency Centres (CECs). CECs pro...

    Authors: Jill A Hayden, Lara Killian, Austin Zygmunt, Jessica Babineau, Ruth Martin-Misener, Jan L Jensen and Alix J Carter
    Citation: Systematic Reviews 2015 4:7
  18. A major problem arising from searching across bibliographic databases is the retrieval of duplicate citations. Removing such duplicates is an essential task to ensure systematic reviewers do not waste time scr...

    Authors: John Rathbone, Matt Carter, Tammy Hoffmann and Paul Glasziou
    Citation: Systematic Reviews 2015 4:6
  19. The large and growing number of published studies, and their increasing rate of publication, makes the task of identifying relevant studies in an unbiased way for inclusion in systematic reviews both complex a...

    Authors: Alison O’Mara-Eves, James Thomas, John McNaught, Makoto Miwa and Sophia Ananiadou
    Citation: Systematic Reviews 2015 4:5

    The Erratum to this article has been published in Systematic Reviews 2015 4:59

  20. The rapid pace of modern life requires working-age women to juggle occupational, family, and social demands. Despite the large numbers of working-age women in developed countries and the proven benefits of reg...

    Authors: Jennifer L Reed, Stephanie A Prince, Christie A Cole, Kara A Nerenberg, Swapnil Hiremath, Heather E Tulloch, J George Fodor, Agnieszka Szczotka, Lisa A McDonnell, Kerri-Anne Mullen, Andrew L Pipe and Robert D Reid
    Citation: Systematic Reviews 2015 4:3
  21. Overweight and obesity, which have a substantial impact on health in the general population, have similar prevalence in solid organ transplant recipients but carry even more serious ramifications. As this grou...

    Authors: Sonja Beckmann, Nataša Ivanović, Gerda Drent, Todd Ruppar and Sabina De Geest
    Citation: Systematic Reviews 2015 4:2
  22. Systematic reviews should build on a protocol that describes the rationale, hypothesis, and planned methods of the review; few reviews report whether a protocol exists. Detailed, well-described protocols can f...

    Authors: David Moher, Larissa Shamseer, Mike Clarke, Davina Ghersi, Alessandro Liberati, Mark Petticrew, Paul Shekelle and Lesley A Stewart
    Citation: Systematic Reviews 2015 4:1
  23. Researchers often wish to carry out additional calculations or analyses using the survival data from one or more studies of other authors. When it is not possible to obtain the raw data directly, reconstructio...

    Authors: Zhihui Liu, Benjamin Rich and James A Hanley
    Citation: Systematic Reviews 2014 3:151
  24. Pharmacological thromboprophylaxis in the peri-operative period involves a trade-off between reduction in venous thromboembolism (VTE) and an increase in bleeding. Baseline risks, in the absence of prophylaxis...

    Authors: Kari AO Tikkinen, Arnav Agarwal, Samantha Craigie, Rufus Cartwright, Michael K Gould, Jari Haukka, Richard Naspro, Giacomo Novara, Per Morten Sandset, Reed A Siemieniuk, Philippe D Violette and Gordon H Guyatt
    Citation: Systematic Reviews 2014 3:150
  25. Experimental designs for evaluating knowledge translation (KT) interventions for professional behavior change can provide strong estimates of intervention effectiveness but offer limited insight how the interv...

    Authors: Shannon D Scott, Thomas Rotter, Lisa Hartling, Thane Chambers and Katherine H Bannar-Martin
    Citation: Systematic Reviews 2014 3:149
  26. Dietary interventions are considered an important aspect of clinical practice, more so in the face of the rising prevalence of obesity, diabetes and cardiovascular diseases globally. Routinely, most doctors do...

    Authors: Victor Mogre, Albert Scherpbier, Tim Dornan, Fred Stevens, Paul Armah Aryee and Mary Gemma Cherry
    Citation: Systematic Reviews 2014 3:148
  27. The rapid pace of modern life requires working-age women to juggle occupational, family and social demands. This modern lifestyle has been shown to have a detrimental effect on health, often associated with in...

    Authors: Jennifer L Reed, Stephanie A Prince, Christie A Cole, J George Fodor, Swapnil Hiremath, Kerri-Anne Mullen, Heather E Tulloch, Erica Wright and Robert D Reid
    Citation: Systematic Reviews 2014 3:147
  28. In the Middle East and North Africa (MENA), hepatitis C virus (HCV) distribution appears to present a wide range of prevalence. The scale and nature of HCV disease burden is poorly known in the Horn of Africa ...

    Authors: Karima Chaabna, Yousra A Mohamoud, Hiam Chemaitelly, Ghina R Mumtaz and Laith J Abu-Raddad
    Citation: Systematic Reviews 2014 3:146
  29. Suicide is a major public health problem and globally is the second leading cause of death in young adults. Globally, there are 164,000 suicides per year in young people under 25 years. Depression is a strong ...

    Authors: Lynda Tait and Maria Michail
    Citation: Systematic Reviews 2014 3:145
  30. The Cochrane risk of bias (RoB) tool has been widely embraced by the systematic review community, but several studies have reported that its reliability is low. We aim to investigate whether training of raters...

    Authors: Bruno R da Costa, Nina M Resta, Brooke Beckett, Nicholas Israel-Stahre, Alison Diaz, Bradley C Johnston, Matthias Egger, Peter Jüni and Susan Armijo-Olivo
    Citation: Systematic Reviews 2014 3:144
  31. Practical solutions are needed to support the appropriate use of available health system resources as countries are continually pressured to ‘do more with less’ in health care. Increasingly, health systems and...

    Authors: Michael G Wilson, Moriah E Ellen, John N Lavis, Jeremy M Grimshaw, Kaelan A Moat, Joshua Shemer, Terry Sullivan, Sarah Garner, Ron Goeree, Roberto Grilli, Justin Peffer and Kevin Samra
    Citation: Systematic Reviews 2014 3:143
  32. A rigorous and focused systematic review and meta-analysis of randomised controlled trials (RCTs) of individualised homeopathic treatment has not previously been undertaken. We tested the hypothesis that the o...

    Authors: Robert T Mathie, Suzanne M Lloyd, Lynn A Legg, Jürgen Clausen, Sian Moss, Jonathan RT Davidson and Ian Ford
    Citation: Systematic Reviews 2014 3:142
  33. Participation in leisure-time physical activity benefits health and is thought to be more prevalent in higher socioeconomic groups. Evidence indicates that childhood socioeconomic circumstances may have long-t...

    Authors: Ahmed Elhakeem, Rachel Cooper, David Bann and Rebecca Hardy
    Citation: Systematic Reviews 2014 3:141
  34. Prognostic factors are associated with the risk of future health outcomes in individuals with a particular health condition. The prognostic ability of such factors is increasingly being assessed in both primar...

    Authors: Janine Dretzke, Joie Ensor, Sue Bayliss, James Hodgkinson, Marie Lordkipanidzé, Richard D Riley, David Fitzmaurice and David Moore
    Citation: Systematic Reviews 2014 3:140
  35. Systematic reviews often investigate the effectiveness of interventions for one sex. However, identifying interventions with data presented according to the sex of study participants can be challenging due to ...

    Authors: Fiona Stewart, Cynthia Fraser, Clare Robertson, Alison Avenell, Daryll Archibald, Flora Douglas, Pat Hoddinott, Edwin van Teijlingen and Dwayne Boyers
    Citation: Systematic Reviews 2014 3:78
  36. There are more than 100,000 asylum seekers registered in Germany, who are granted limited access to health services. This study aims to provide a systematic overview of the empirical literature on the health s...

    Authors: Christine Schneider, Amir Mohsenpour, Stefanie Joos and Kayvan Bozorgmehr
    Citation: Systematic Reviews 2014 3:139
  37. Industry sponsorship has been identified as a factor correlating with positive research findings in several fields of medical science. To date, the influence of industry sponsorship in general and abdominal su...

    Authors: Pascal Probst, Kathrin Grummich, Alexis Ulrich, Markus W Büchler, Phillip Knebel and Markus K Diener
    Citation: Systematic Reviews 2014 3:138
  38. There is no consensus on how authors conducting meta-analysis should deal with trial participants with missing outcome data. The objectives of this study are to assess in Cochrane and non-Cochrane systematic r...

    Authors: Elie A Akl, Lara A Kahale, Arnav Agarwal, Nada Al-Matari, Shanil Ebrahim, Paul Elias Alexander, Matthias Briel, Romina Brignardello-Petersen, Jason W Busse, Batoul Diab, Alfonso Iorio, Joey Kwong, Ling Li, Luciane Cruz Lopes, Reem Mustafa, Ignacio Neumann…
    Citation: Systematic Reviews 2014 3:137
  39. Although abbreviated surgery with planned reoperation (damage control surgery) is now widely used to manage major trauma patients, the procedure and its component interventions have not been evaluated in rando...

    Authors: Nela Cosic, Derek J Roberts and Henry T Stelfox
    Citation: Systematic Reviews 2014 3:136
  40. Strong opinions for or against the use of systematic reviews to inform policymaking have been published in the medical literature. The purpose of this paper was to examine whether funding sources and author fi...

    Authors: Susan R Forsyth, Donna H Odierna, David Krauth and Lisa A Bero
    Citation: Systematic Reviews 2014 3:122
  41. The purpose of our study is to determine the value and efficacy of searching biomedical databases beyond MEDLINE for systematic reviews.

    Authors: Yoojin Kwon, Susan E Powelson, Holly Wong, William A Ghali and John M Conly
    Citation: Systematic Reviews 2014 3:135
  42. Chronic pain disorders impact the physical, psychological, social, and financial well-being of between 10%–30% of Canadians. The primary aims of psychological interventions targeting chronic pain disorders are...

    Authors: Taylor Hatchard, Chris Lepage, Brian Hutton, Becky Skidmore and Patricia A Poulin
    Citation: Systematic Reviews 2014 3:134
  43. Major depressive disorder (MDD) is a debilitating and costly mental disorder. Although commercially available antidepressants have proliferated over the last 20 years, a substantial number of patients either d...

    Authors: Yiyun Liu, Xinyu Zhou, Bin Qin, Cinzia Del Giovane, Yuqing Zhang and Peng Xie
    Citation: Systematic Reviews 2014 3:133
  44. The majority of North American adult females do not meet current physical activity recommendations (150 min of moderate-to-vigorous intensity physical activity (MVPA) per week accrued in ≥10 min bouts) ultimat...

    Authors: Stephanie A Prince, Jennifer L Reed, Kara A Nerenberg, Elizabeth A Kristjansson, Swapnil Hiremath, Kristi B Adamo, Heather E Tulloch, Kerri-Anne Mullen, J George Fodor, Erica Wright and Robert D Reid
    Citation: Systematic Reviews 2014 3:132
  45. Pregnant women who gain excess weight are at risk of complications during pregnancy and in the long term. Interventions based on diet and physical activity minimise gestational weight gain with varied effect o...

    Authors: Anneloes E Ruifrok, Ewelina Rogozinska, Mireille NM van Poppel, Girish Rayanagoudar, Sally Kerry, Christianne JM de Groot, SeonAe Yeo, Emma Molyneaux, Fionnuala M McAuliffe, Lucilla Poston, Tracy Roberts, Richard D Riley, Arri Coomarasamy, Khalid Khan, Ben Willem Mol and Shakila Thangaratinam
    Citation: Systematic Reviews 2014 3:131

    The Erratum to this article has been published in Systematic Reviews 2015 4:101

  46. The aim of this meta-analysis was to compare the long-term efficacy of diet plus exercise (D + E) vs. diet (D), D + E vs. exercise (E) and D vs. E on anthropometric outcomes and cardiovascular risk factors in ...

    Authors: Lukas Schwingshackl, Sofia Dias and Georg Hoffmann
    Citation: Systematic Reviews 2014 3:130

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