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  1. Content type: Protocol

    Women in high resource nations are increasingly delaying childbearing until their thirties. Delayed childbearing poses challenges for the spacing of a woman’s pregnancies. Inter-pregnancy intervals <12 months ...

    Authors: Mani Asgharpour, Sofia Villarreal, Laura Schummers, Jennifer Hutcheon, Dorothy Shaw and Wendy V. Norman

    Citation: Systematic Reviews 2017 6:75

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  2. Content type: Protocol

    Overviews of systematic reviews (overviews) attempt to systematically retrieve and summarize the results of multiple systematic reviews (SRs) for a given condition or public health problem. Two prior descripti...

    Authors: Dawid Pieper, Michelle Pollock, Ricardo M. Fernandes, Roland Brian Büchter and Lisa Hartling

    Citation: Systematic Reviews 2017 6:73

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  3. Content type: Protocol

    Atrial fibrillation is the most common arrhythmia of the heart with a prevalence of approximately 2% in the western world. Atrial flutter, another arrhythmia, occurs less often with an incidence of approximate...

    Authors: Naqash J. Sethi, Sanam Safi, Joshua Feinberg, Emil E. Nielsen, Christian Gluud and Janus C. Jakobsen

    Citation: Systematic Reviews 2017 6:71

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  4. Content type: Protocol

    HIV self-testing (HIVST) is becoming popular with policy makers and commissioners globally, with a key aim of expanding access through reducing barriers to testing for individuals at risk of HIV infection. HIV...

    Authors: T. Charles Witzel, Peter Weatherburn, Fiona M. Burns, Cheryl C. Johnson, Carmen Figueroa and Alison J. Rodger

    Citation: Systematic Reviews 2017 6:72

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  5. Content type: Protocol

    The objective of this study will be to synthesize the epidemiological evidence and evaluate the validity of the associations between central nervous system disorders and the risk of developing or dying from ca...

    Authors: Ferrán Catalá-López, Brian Hutton, Jane A. Driver, Matthew J. Page, Manuel Ridao, José M. Valderas, Adolfo Alonso-Arroyo, Jaume Forés-Martos, Salvador Martínez, Ricard Gènova-Maleras, Diego Macías-Saint-Gerons, Benedicto Crespo-Facorro, Eduard Vieta, Alfonso Valencia and Rafael Tabarés-Seisdedos

    Citation: Systematic Reviews 2017 6:69

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  6. Content type: Protocol

    The majority of a child’s language development occurs in the first 5 years of life when brain development is most rapid. There are significant long-term benefits to supporting all children’s language and liter...

    Authors: Laureen J. McIntyre, Laurie-ann M. Hellsten, Julia Bidonde, Catherine Boden and Carolyn Doi

    Citation: Systematic Reviews 2017 6:70

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  7. Content type: Protocol

    Evidence suggests a relationship between human immunodeficiency virus (HIV) infection and chronic obstructive pulmonary disease (COPD). Although the high burden of COPD and the HIV disease is clearly demonstra...

    Authors: Jean Joel R. Bigna, Angeladine Malaha Kenne and Serra Lem Asangbeh

    Citation: Systematic Reviews 2017 6:68

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  8. Content type: Protocol

    Failure to promptly identify deterioration in hospitalised patients is associated with delayed admission to intensive care units (ICUs) and poor outcomes. Existing vital sign-based Early Warning Score (EWS) al...

    Authors: James Malycha, Tim Bonnici, Katarina Sebekova, Tatjana Petrinic, Duncan Young and Peter Watkinson

    Citation: Systematic Reviews 2017 6:67

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  9. Content type: Protocol

    Cancer survivors face a range of negative physical and psychological effects that can be mitigated by participating in physical activity. Despite this, most do not meet recommended levels. Health care provider...

    Authors: Jennifer Brunet, Amanda Wurz, Connor O’Rielly, Doris Howell, Mathieu Bélanger and Jonathan Sussman

    Citation: Systematic Reviews 2017 6:66

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  10. Content type: Research

    A rigorous systematic review and meta-analysis focused on randomised controlled trials (RCTs) of non-individualised homeopathic treatment has not previously been reported. We tested the null hypothesis that th...

    Authors: Robert T. Mathie, Nitish Ramparsad, Lynn A. Legg, Jürgen Clausen, Sian Moss, Jonathan R. T. Davidson, Claudia-Martina Messow and Alex McConnachie

    Citation: Systematic Reviews 2017 6:63

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  11. Content type: Protocol

    Comprehensive geriatric assessment (CGA) is an integrated model of care involving a geriatrician and an interdisciplinary team and can prioritize and manage complex health needs of older adults with multimorbi...

    Authors: Charlene Soobiah, Caitlin Daly, Erik Blondal, Joycelyne Ewusie, Joanne Ho, Meghan J. Elliott, Rossini Yue, Jayna Holroyd-Leduc, Barbara Liu, Sharon Marr, Jenny Basran, Andrea C. Tricco, Jemila Hamid and Sharon E. Straus

    Citation: Systematic Reviews 2017 6:65

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  12. Content type: Research

    Spinal manipulative therapy (SMT) is a widely used manual treatment, but many reviews exist with conflicting conclusions about the safety of SMT. We performed an overview of reviews to elucidate and quantify t...

    Authors: Sabrina Mai Nielsen, Simon Tarp, Robin Christensen, Henning Bliddal, Louise Klokker and Marius Henriksen

    Citation: Systematic Reviews 2017 6:64

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  13. Content type: Research

    Systematic reviews of qualitative and quantitative evidence can provide a rich understanding of complex phenomena. This type of review is increasingly popular, has been used to provide a landscape of existing ...

    Authors: Quan Nha Hong, Pierre Pluye, Mathieu Bujold and Maggy Wassef

    Citation: Systematic Reviews 2017 6:61

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  14. Content type: Protocol

    Parental sensitivity is the interaction process by which parents (a) recognize cues from their infant, (b) interpret these cues adequately, (c) identify an appropriate response and (d) apply this response in a...

    Authors: Andréane Lavallée, Marilyn Aita, Anne Bourbonnais and Gwenaëlle De Clifford-Faugère

    Citation: Systematic Reviews 2017 6:62

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  15. Content type: Protocol

    Frequently cited benefit-cost ratios suggest that interventions to improve neurodevelopment have high economic returns when implemented during pregnancy and early childhood. However, there are many challenges ...

    Authors: Karen M. Edmond, Natalie A. Strobel, Kimberley McAuley, Elizabeth Geelhoed and Lisa Hurt

    Citation: Systematic Reviews 2017 6:59

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  16. Content type: Protocol

    Suboptimal thyroid hormone therapy including under-replacement and over-replacement is common amongst patients with hypothyroidism. This is a significant health concern as affected patients are at risk of adve...

    Authors: Rosie Dew, Onyebuchi Okosieme, Colin Dayan, Vinay Eligar, Ishrat Khan, Salman Razvi, Simon Pearce and Scott Wilkes

    Citation: Systematic Reviews 2017 6:60

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  17. Content type: Protocol

    Dietary advice is one of the cornerstones in the management of type 2 diabetes mellitus. The American Diabetes Association recommended a hypocaloric diet for overweight or obese adults with type 2 diabetes in ...

    Authors: Lukas Schwingshackl, Anna Chaimani, Georg Hoffmann, Carolina Schwedhelm and Heiner Boeing

    Citation: Systematic Reviews 2017 6:57

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  18. Content type: Methodology

    Decision support tools build upon comprehensive and timely syntheses of literature. Rapid reviews may allow supporting their development by omitting certain components of traditional systematic reviews. We thu...

    Authors: Moulikatou Adouni Lawani, Béatriz Valéra, Émilie Fortier-Brochu, France Légaré, Pierre-Hugues Carmichael, Luc Côté, Philippe Voyer, Edeltraut Kröger, Holly Witteman, Charo Rodriguez and Anik M. C. Giguere

    Citation: Systematic Reviews 2017 6:56

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  19. Content type: Research

    Dysvascular partial foot amputation (PFA) is a common sequel to advanced peripheral vascular disease. Helping inform difficult discussions between patients and practitioners about the level of PFA, or the deci...

    Authors: Michael P. Dillon, Matthew Quigley and Stefania Fatone

    Citation: Systematic Reviews 2017 6:54

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  20. Content type: Research

    Physical frailty is a prevalent syndrome in older adults that increases vulnerability for a range of adverse outcomes including increased dependency and death. Caregivers of older adults experience significant...

    Authors: Thom Ringer, Afeez Abiola Hazzan, Arnav Agarwal, Adam Mutsaers and Alexandra Papaioannou

    Citation: Systematic Reviews 2017 6:55

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  21. Content type: Protocol

    Human papillomavirus (HPV) is the most prevalent genital infection, especially in young women of reproductive age. In vitro and animal model experiments provide compelling evidence of the harmful effect of HPV...

    Authors: Joseph Niyibizi, Nadège Zanré, Marie-Hélène Mayrand and Helen Trottier

    Citation: Systematic Reviews 2017 6:53

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  22. Content type: Protocol

    The aim of this individual participant data meta-analysis (IPDMA) is to evaluate the effects of dietary and lifestyle interventions among pregnant women who are overweight or obese on later maternal and early ...

    Authors: Jodie M. Dodd, Rosalie M. Grivell, Jennie Louise, Andrea R. Deussen, Lynne Giles, Ben W. Mol, Christina Vinter, Mette Tanvig, Dorte Moller Jensen, Annick Bogaerts, Roland Devlieger, Riitta Luoto, Fionnuala McAuliffe, Kristina Renault, Emma Carlsen, Nina Geiker…

    Citation: Systematic Reviews 2017 6:51

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  23. Content type: Protocol

    There is a lack of high-level evidence on the surgical management of cleft palate. An appreciation of the differences in the complication rates between different surgical techniques and timing of repair is ess...

    Authors: Zach Zhang, Michael Stein, Nigel Mercer and Claudia Malic

    Citation: Systematic Reviews 2017 6:52

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