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  1. Content type: Protocol

    Primary care electronic medical record (EMR) data are being used for research, surveillance, and clinical monitoring. To broaden the reach and usability of EMR data, case definitions must be specified to ident...

    Authors: Sepideh Souri, Nicola E. Symonds, Azin Rouhi, Brendan C. Lethebe, Stephanie Garies, Paul E. Ronksley, Tyler S. Williamson, Gabriel E. Fabreau, Richard Birtwhistle, Hude Quan and Kerry A. McBrien

    Citation: Systematic Reviews 2017 6:38

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  2. Content type: Protocol

    Chronic kidney disease (CKD) is associated with an increased risk of fracture and cardiovascular mortality. The risk of fracture in hemodialysis (HD), peritoneal dialysis (PD), and kidney transplantation (KT) ...

    Authors: Aboubacar Sidibé, Lynne Moore, Sonia Jean and Fabrice Mac-Way

    Citation: Systematic Reviews 2017 6:37

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  3. Content type: Protocol

    Colorectal cancer (CRC) is a common and important disease. There are different tests for diagnosis, one of which is computed tomographic colonography (CTC). No test is perfect, and patients with normal CTC may...

    Authors: Andrew A. Plumb, Anu Obaro, Thomas Fanshawe, Ulysses S. Torres, Rachel Baldwin-Cleland, Steve Halligan and David Burling

    Citation: Systematic Reviews 2017 6:36

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  4. Content type: Protocol

    There is limited information about how transgender, gender diverse, and Two-Spirit (trans) people have been represented and studied by researchers. The objectives of this study are to (1) map and describe tran...

    Authors: Zack Marshall, Vivian Welch, James Thomas, Fern Brunger, Michelle Swab, Ian Shemilt and Chris Kaposy

    Citation: Systematic Reviews 2017 6:35

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  5. Content type: Protocol

    Effective knowledge translation (KT) is critical to implementing program and policy changes that require shared understandings of knowledge systems, assumptions, and practices. Within mainstream research insti...

    Authors: Melody E. Morton Ninomiya, Donna Atkinson, Simon Brascoupé, Michelle Firestone, Nicole Robinson, Jeff Reading, Carolyn P. Ziegler, Raglan Maddox and Janet K. Smylie

    Citation: Systematic Reviews 2017 6:34

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  6. Content type: Protocol

    Despite limited evidence of effectiveness, withdrawal (discontinuation or dose reduction) of high risk medications known as “fall-risk increasing drugs” (FRIDs) is typically conducted as a fall prevention stra...

    Authors: Justin Yusen Lee and Anne Holbrook

    Citation: Systematic Reviews 2017 6:33

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  7. Content type: Research

    There is increasing demand for rapid reviews and timely evidence synthesis. The goal of this project was to understand end-user perspectives on the utility and limitations of rapid products including evidence ...

    Authors: Lisa Hartling, Jeanne-Marie Guise, Susanne Hempel, Robin Featherstone, Matthew D. Mitchell, Makalapua L. Motu’apuaka, Karen A. Robinson, Karen Schoelles, Annette Totten, Evelyn Whitlock, Timothy J. Wilt, Johanna Anderson, Elise Berliner, Aysegul Gozu, Elisabeth Kato, Robin Paynter…

    Citation: Systematic Reviews 2017 6:32

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  8. Content type: Research

    It is uncertain whether the replication of systematic reviews, particularly those with the same objectives and resources, would employ similar methods and/or arrive at identical findings. We compared the resul...

    Authors: Jeffrey Low, Joseph S. Ross, Jessica D. Ritchie, Cary P. Gross, Richard Lehman, Haiqun Lin, Rongwei Fu, Lesley A. Stewart and Harlan M. Krumholz

    Citation: Systematic Reviews 2017 6:28

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  9. Content type: Protocol

    Little is known about the mechanisms that influence the success or failure of programs to facilitate re-engagement with health and social services for formerly incarcerated persons with HIV. This review aims t...

    Authors: Jenkin Tsang, Sharmistha Mishra, Janet Rowe, Patricia O’Campo, Carolyn Ziegler, Fiona G. Kouyoumdjian, Flora I. Matheson, Ahmed M. Bayoumi, Shatabdy Zahid and Tony Antoniou

    Citation: Systematic Reviews 2017 6:29

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  10. Content type: Protocol

    Perinatal morbidity and mortality remain significant public health issues globally, with enduring impact on the health and well-being of women and their families. Pregnant women who adopt, practice and maintai...

    Authors: Lisa M. Daly, Dell Horey, Philippa F. Middleton, Frances M. Boyle and Vicki Flenady

    Citation: Systematic Reviews 2017 6:26

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  11. Content type: Protocol

    Muslims comprise 4.8% of the national population in the UK and also form a significant proportion of its ethnic minority population, with trends set to continue for the foreseeable future. With ethnic minority...

    Authors: Yassar Mustafa, Diya Baker, Preeti Puligari, Teresa Melody, Joyce Yeung and Fang Gao-Smith

    Citation: Systematic Reviews 2017 6:25

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  12. Content type: Protocol

    Despite the surge of research and development in assistive products for older adults and/or people living with disabilities, policies on access and procurement have lagged in responding to the growing demand f...

    Authors: Winnie Sun, Michael G. Wilson, Daphne Schreiber and Rosalie H. Wang

    Citation: Systematic Reviews 2017 6:24

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  13. Content type: Research

    Rapid reviews are increasingly being used to help policy makers access research in short time frames. A clear articulation of the review’s purpose, questions, scope, methods and reporting format is thought to ...

    Authors: Gabriel Moore, Sally Redman, Catherine D’Este, Steve Makkar and Tari Turner

    Citation: Systematic Reviews 2017 6:23

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  14. Content type: Protocol

    Chronic low back pain (LBP) is the leading cause of pain and disability, resulting in a major socioeconomic impact. The Cochrane Review which examined the effect of spinal manipulative therapy (SMT) for chroni...

    Authors: A. de Zoete, M. R. de Boer, M. W. van Tulder, S. M. Rubinstein, M. Underwood, J. A. Hayden, J. Kalter and R. Ostelo

    Citation: Systematic Reviews 2017 6:21

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  15. Content type: Protocol

    Acute respiratory infections (ARI) are a leading cause of morbidity and mortality globally, and are often linked to seasonal and/or meteorological conditions. Globally, Indigenous peoples may experience a diff...

    Authors: Katherine E. Bishop-Williams, Jan M. Sargeant, Lea Berrang-Ford, Victoria L. Edge, Ashlee Cunsolo and Sherilee L. Harper

    Citation: Systematic Reviews 2017 6:19

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  16. Content type: Protocol

    Chewing and masticatory function constitutes one of the most important oral health factors that affect quality of life, especially in older individuals. Little consensus currently exists regarding ways to obje...

    Authors: Per Elgestad Stjernfeldt, Inger Wårdh, Mats Trulsson, Gerd Faxén Irving and Anne-Marie Boström

    Citation: Systematic Reviews 2017 6:20

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  17. Content type: Protocol

    Dementia and cognitive impairment could severely impact patients’ life and bring heavy burden to patients, caregivers and societies. Some interventions are suggested for the older patients with these condition...

    Authors: Fan Yang, Piers Dawes, Iracema Leroi and Brenda Gannon

    Citation: Systematic Reviews 2017 6:22

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  18. Content type: Protocol

    Pregnancy and childbirth are important risk factors for urinary incontinence (UI) in women. Pelvic floor muscle exercises (PFME) are effective for prevention of UI. Guidelines for the management of UI recommen...

    Authors: Victoria E. Salmon, E. Jean C. Hay-Smith, Rachel Jarvie, Sarah Dean, Eivor Oborn, Susan E. Bayliss, Debra Bick, Clare Davenport, Khaled M. Ismail, Christine MacArthur and Mark Pearson

    Citation: Systematic Reviews 2017 6:18

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  19. Content type: Research

    Youth comprise 40% of the world’s unemployed, a status associated with adverse wellbeing and social, health, and economic costs. This systematic review and meta-analysis review synthesises the literature on th...

    Authors: Lauren Mawn, Emily J. Oliver, Nasima Akhter, Clare L. Bambra, Carole Torgerson, Chris Bridle and Helen J. Stain

    Citation: Systematic Reviews 2017 6:16

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  20. Content type: Protocol

    Sexually transmitted infection with high-risk, oncogenic strains of human papillomavirus (HPV) still induces a relevant burden of diseases on both men and women. Although vaccines appear to be highly efficacio...

    Authors: Giampiero Favato, Emmanouil Noikokyris and Riccardo Vecchiato

    Citation: Systematic Reviews 2017 6:17

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  21. Content type: Protocol

    Chronic non-healing wounds present a substantial economic burden to healthcare system; significant reductions in quality of life for those affected, and precede often serious events such as limp amputations or...

    Authors: Krister Järbrink, Gao Ni, Henrik Sönnergren, Artur Schmidtchen, Caroline Pang, Ram Bajpai and Josip Car

    Citation: Systematic Reviews 2017 6:15

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  22. Content type: Protocol

    Good patient-pharmacist communication improves health outcomes. There is, however, room for improving pharmacists’ communication skills. These develop through complex interactions during undergraduate pharmacy...

    Authors: Aisling Kerr, Judith Strawbridge, Caroline Kelleher, Fien Mertens, Peter Pype, Myriam Deveugele and Teresa Pawlikowska

    Citation: Systematic Reviews 2017 6:14

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  23. Content type: Protocol

    Celebrities are highly influential people whose actions and decisions are watched and often emulated by wide audiences. Many celebrities have used their prominent social standing to offer medical advice or end...

    Authors: Steven J. Hoffman, Yasmeen Mansoor, Navneet Natt, Lathika Sritharan, Julia Belluz, Timothy Caulfield, Yoni Freedhoff, John N. Lavis and Arya M. Sharma

    Citation: Systematic Reviews 2017 6:13

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  24. Content type: Protocol

    Injury represents one of the greatest public health challenges of our time with over 5 million deaths and 100 million people temporarily or permanently disabled every year worldwide. The effectiveness of traum...

    Authors: Lynne Moore, Howard Champion, Gerard O’Reilly, Ari Leppaniemi, Peter Cameron, Cameron Palmer, Fikri M. Abu-Zidan, Belinda Gabbe, Christine Gaarder, Natalie Yanchar, Henry Thomas Stelfox, Raul Coimbra, John Kortbeek, Vanessa Noonan, Amy Gunning, Luke Leenan…

    Citation: Systematic Reviews 2017 6:12

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  25. Content type: Protocol

    Planning for pregnancy has been associated with reduced unwanted pregnancies and improved pregnancy outcomes. Despite the benefits of planned pregnancy, there are no guideline recommendations on routine counse...

    Authors: Paul A. Henning, Carolyne K. Burgess, Heidi E. Jones and Wendy V. Norman

    Citation: Systematic Reviews 2017 6:11

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  26. Content type: Protocol

    Postgraduate medical education and training (PGMET) is a complex social process which happens predominantly during the delivery of patient care. The clinical learning environment (CLE), the context for PGMET, ...

    Authors: Anel Wiese, Caroline Kilty, Colm Bergin, Patrick Flood, Na Fu, Mary Horgan, Agnes Higgins, Bridget Maher, Grainne O’Kane, Lucia Prihodova, Dubhfeasa Slattery and Deirdre Bennett

    Citation: Systematic Reviews 2017 6:10

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  27. Content type: Protocol

    Patients who are discharged from hospital after an acute medical illness often have impaired function that prevents them from returning to their previous place of residence. Assessing each patient’s post-disch...

    Authors: Daniel M. Kobewka, Daniel McIsaac, Michaël Chassé, Kednapa Thavorn, Sunita Mulpuru, Luke T. Lavallée, Shane English, Justin Presseau and Alan J. Forster

    Citation: Systematic Reviews 2017 6:8

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  28. Content type: Protocol

    In South Africa, gender inequality dominated by males and heterosexual HIV epidemic are associated with high HIV infection. Underlying epidemiological and social determinants driving HIV acquisition and transm...

    Authors: Nonzwakazi Ntombela, Tivani P. Mashamba-Thompson, Andile Mtshali, Anna Voce and Ayesha B. M. Kharsany

    Citation: Systematic Reviews 2017 6:9

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  29. Content type: Protocol

    Cerebral small vessel disease (CSVD) is a common cause of stroke, dementia, and functional decline. In recent years, neuroradiologic correlates of CSVD have been identified. These imaging findings, best charac...

    Authors: Clark Funnell, Mary M. Doyle-Waters, Samuel Yip and Thalia Field

    Citation: Systematic Reviews 2017 6:7

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  30. Content type: Protocol

    Multi-drug-resistant tuberculosis (MDR-TB) has emerged as a challenge to global tuberculosis (TB) control and remains a major public health concern in many countries. Diabetes mellitus (DM) is an increasingly ...

    Authors: Balewgizie Sileshi Tegegne, Tesfa Dejenie Habtewold, Melkamu Merid Mengesha and Johannes G.M. Burgerhof

    Citation: Systematic Reviews 2017 6:6

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  31. Content type: Protocol

    Despite the well-established morbidity, mortality, long-term effects, and unnecessary extra-cost burden associated with cesarean section delivery (CSD) worldwide, its rate has grown exponentially. This has bec...

    Authors: Idrissa Beogo, Bomar Mendez Rojas and Marie-Pierre Gagnon

    Citation: Systematic Reviews 2017 6:5

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  32. Content type: Protocol

    There is wide agreement that there is a lack of attention to health in municipal environmental policy-making, such as urban planning and regeneration. Explanations for this include differing professional norms...

    Authors: Helen Pineo, Ketevan Glonti, Harry Rutter, Nicole Zimmermann, Paul Wilkinson and Michael Davies

    Citation: Systematic Reviews 2017 6:2

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  33. Content type: Protocol

    Bruxism is a sleep disorder characterized by grinding and clenching of the teeth that may be related to irreversible tooth injuries. It is a prevalent condition occurring in up to 31% of adults. However, there...

    Authors: Mauro Elias Mesko, Brian Hutton, Jovito Adiel Skupien, Rafael Sarkis-Onofre, David Moher and Tatiana Pereira-Cenci

    Citation: Systematic Reviews 2017 6:4

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  34. Content type: Research

    People’s ability to appraise claims about treatment effects is crucial for informed decision-making. Our objective was to systematically map this area of research in order to (a) provide an overview of interve...

    Authors: Astrid Austvoll-Dahlgren, Allen Nsangi and Daniel Semakula

    Citation: Systematic Reviews 2016 5:215

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  35. Content type: Protocol

    Clinical trials typically have a relatively short follow-up period, and may both underestimate potential benefits of treatments investigated, and fail to detect hazards, which can take much longer to emerge. P...

    Authors: Rebecca Llewellyn-Bennett, Louise Bowman and Richard Bulbulia

    Citation: Systematic Reviews 2016 5:214

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  36. Content type: Protocol

    Colonic mural thickening is often a finding in standard computed tomography (CT) scans of the abdomen. It often presents clinician with a dilemma on when a further endoscopic evaluation is needed, especially i...

    Authors: Subashini Chandrapalan, Faraz Tahir, Rakesh Sinha and Ramesh Arasaradnam

    Citation: Systematic Reviews 2016 5:213

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  37. Content type: Research

    As more complex meta-analytical techniques such as network and multivariate meta-analyses become increasingly common, further pressures are placed on reviewers to extract data in a systematic and consistent ma...

    Authors: Hugo Pedder, Grammati Sarri, Edna Keeney, Vanessa Nunes and Sofia Dias

    Citation: Systematic Reviews 2016 5:212

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  38. Content type: Protocol

    The prevalence of delirium in intensive care unit (ICU) patients is high. Delirium has been associated with morbidity and mortality including more ventilator days, longer ICU stay, increased long-term mortalit...

    Authors: Marija Barbateskovic, Laura Krone Larsen, Marie Oxenbøll-Collet, Janus Christian Jakobsen, Anders Perner and Jørn Wetterslev

    Citation: Systematic Reviews 2016 5:211

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  39. Content type: Methodology

    Synthesis of multiple randomized controlled trials (RCTs) in a systematic review can summarize the effects of individual outcomes and provide numerical answers about the effectiveness of interventions. Filteri...

    Authors: Mourad Ouzzani, Hossam Hammady, Zbys Fedorowicz and Ahmed Elmagarmid

    Citation: Systematic Reviews 2016 5:210

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  40. Content type: Protocol

    Medication errors represent a noteworthy source of harm to patients. In recent years, several systematic reviews have assessed the frequency and causes of these events, as well as other factors such as commonl...

    Authors: Brian Hutton, Salmaan Kanji, Erika McDonald, Fatemeh Yazdi, Dianna Wolfe, Kednapa Thavorn, Sally Pepper, Laurie Chapman, Becky Skidmore and David Moher

    Citation: Systematic Reviews 2016 5:209

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  41. Content type: Protocol

    Behavioural support for smoking cessation in pregnancy can be effective; however, many pregnant women face barriers to seeking support to stop smoking. Some digital interventions have been found to be effectiv...

    Authors: Sarah Ellen Griffiths, Katherine E. Brown, Emily Anne Fulton, Ildiko Tombor and Felix Naughton

    Citation: Systematic Reviews 2016 5:207

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  42. Content type: Protocol

    It is believed increasingly that patients with severe Crohn’s disease are best treated early with biological therapy, which may ameliorate subsequent disease course and diminish long-term complications. Howeve...

    Authors: Steve Halligan, Darren Boone, Gauraang Bhatnagar, Tariq Ahmad, Stuart Bloom, Manuel Rodriguez-Justo, Stuart A. Taylor and Susan Mallett

    Citation: Systematic Reviews 2016 5:206

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  43. Content type: Protocol

    In patients with intracranial large vessel arterial occlusion, ipsilateral extracranial carotid artery occlusions or near-occlusions pose a significant hurdle in endovascular management of acute ischaemic stro...

    Authors: Henrik Steglich-Arnholm, Markus Holtmannspötter, Christian Gluud and Derk Wolfgang Krieger

    Citation: Systematic Reviews 2016 5:208

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  44. Content type: Protocol

    Despite the growing international interest in patient safety as a discipline, there has been a lack of exploration of its application to mental health. It cannot be assumed that findings based upon physical he...

    Authors: Danielle D’Lima, Stephanie Archer, Bethan Ines Thibaut, Sonny Christian Ramtale, Lindsay H. Dewa and Ara Darzi

    Citation: Systematic Reviews 2016 5:203

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  45. Content type: Protocol

    Converging evidence demonstrates the important role of the neuropeptide hormone oxytocin (OT) in human behaviour and cognition. Intranasal OT administration has been shown to improve several aspects of social ...

    Authors: Daniel S. Quintana, Tim Outhred, Lars T. Westlye, Gin S. Malhi and Ole A. Andreassen

    Citation: Systematic Reviews 2016 5:205

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