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  1. Content type: Research

    There is a great deal of variation in the design and delivery of patient navigator (PN) programs, making it difficult to design or adopt these interventions in new contexts. We (1) systematically reviewed the ...

    Authors: Laura Desveaux, Kerry McBrien, Lianne Barnieh and Noah M. Ivers

    Citation: Systematic Reviews 2019 8:8

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  2. Content type: Protocol

    Posttraumatic stress disorder (PTSD) is a disorder that develops following exposure to severely stressful events. Altered cortisol secretion has been reported in PTSD; however, results have been inconsistent. ...

    Authors: Leigh Luella van den Heuvel, Simonne Wright, Sharain Suliman, Tobias Stalder, Clemens Kirschbaum and Soraya Seedat

    Citation: Systematic Reviews 2019 8:7

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  3. Content type: Protocol

    Malnutrition affects a third of the global population with low- and middle-income countries (LMICs) being the most affected. Most of those affected by malnutrition have limited means of determining their nutri...

    Authors: T. S. Dhlamini, D. Kuupiel and T. P. Mashamba-Thompson

    Citation: Systematic Reviews 2019 8:6

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  4. Content type: Protocol

    Pandemic mortality rates in 1918 and in 2009 were highest among those with the lowest socioeconomic status (SES). Despite this, low SES groups are not included in the list of groups prioritized for pandemic va...

    Authors: Svenn-Erik Mamelund, Clare Shelley-Egan and Ole Rogeberg

    Citation: Systematic Reviews 2019 8:5

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  5. Content type: Research

    Metabolic syndrome (MetS) is a constellation of conditions that increase the risk of cardiovascular diseases. It is an emerging concern in sub-Saharan African (SSA) countries, particularly because of an increa...

    Authors: Olamide O. Todowede, Solange Z. Mianda and Benn Sartorius

    Citation: Systematic Reviews 2019 8:4

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  6. Content type: Methodology

    Different tools exist for assessing risk of bias of intervention studies for systematic reviews. We present a tool for assessing risk of bias across both randomized and non-randomized study designs. The tool w...

    Authors: Caitlin E. Kennedy, Virginia A. Fonner, Kevin A. Armstrong, Julie A. Denison, Ping Teresa Yeh, Kevin R. O’Reilly and Michael D. Sweat

    Citation: Systematic Reviews 2019 8:3

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  7. Content type: Protocol

    Median nerve cross-sectional area (CSA) is the primary sonographic parameter for assessing and diagnosing median nerve pathology, such as carpal tunnel syndrome. However, variability in the sensitivity of diag...

    Authors: Sandy C. Takata, Lynn Kysh, Wendy J. Mack and Shawn C. Roll

    Citation: Systematic Reviews 2019 8:2

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  8. Content type: Protocol

    Midwives’ practices during the second stage of labour vary nationally and internationally. We aim to retrieve evidence that supports high-quality intrapartum care by conducting a systematic review of the liter...

    Authors: Corine J. Verhoeven, Dale Spence, Viola Nyman, René H. J. Otten and Maria Healy

    Citation: Systematic Reviews 2019 8:1

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  9. Content type: Protocol

    Toxic alcohols have been implicated in accidental ingestions and intentional exposures. Recognition of toxic alcohol poisoning is challenging. The main treatment modalities include antidotes with alcohol dehyd...

    Authors: Carol Wang, Daniel Samaha, Swapnil Hiremath, Lindsey Sikora, Manish M. Sood, Salmaan Kanji and Edward G. Clark

    Citation: Systematic Reviews 2018 7:250

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  10. Content type: Systematic review update

    Placenta praevia refers to a placenta located in the lower segment of the uterus. This abnormal location predisposes the placenta to abnormal bleeding with an increased risk of premature labour. The merits of ...

    Authors: Frederick Morfaw, Mercy Fundoh, Jessica Bartoszko, Lawrence Mbuagbaw and Lehana Thabane

    Citation: Systematic Reviews 2018 7:249

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  11. Content type: Protocol

    Chlamydia trachomatis and Neisseria gonorrhoeae are the most commonly reported sexually transmitted infections in Canada. Existing national guidance on screening for these infections was not based on a systematic...

    Authors: Jennifer Pillay, Ainsley Moore, Prinon Rahman, Gabriel Lewin, Donna Reynolds, John Riva, Guyléne Thériault, Brett Thombs, Brenda Wilson, Joan Robinson, Amanda Ramdyal, Geneviéve Cadieux, Robin Featherstone, Anne N. Burchell, Jo-Anne Dillon, Ameeta Singh…

    Citation: Systematic Reviews 2018 7:248

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  12. Content type: Protocol

    Achilles tendon ruptures are a common injury and are increasing in incidence. Several management strategies exist for both non-operative and operative care, with each strategy offering unique risks and benefit...

    Authors: Brad Meulenkamp, Dawn Stacey, Dean Fergusson, Brian Hutton, Risa Shorr MLIS and Ian D. Graham

    Citation: Systematic Reviews 2018 7:247

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  13. Content type: Protocol

    Antimicrobial resistance generates a huge health and economic burden and has the potential to become the leading cause of death globally, but its underlying drivers are yet to be fully described. The associati...

    Authors: Titus H. Divala, Elizabeth L. Corbett, Helen R. Stagg, Marriott Nliwasa, Derek J. Sloan, Neil French and Katherine L. Fielding

    Citation: Systematic Reviews 2018 7:246

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  14. Content type: Protocol

    There is a significant worldwide increase in type 2 diabetes mellitus and gestational diabetes (T2DM/GDM) linked to a range of associated comorbidities and rising healthcare costs. It has been shown that an in...

    Authors: Jessica Breuing, Dawid Pieper, Annika Lena Neuhaus, Simone Heß, Lena Lütkemeier, Fabiola Haas, Mark Spiller and Christine Graf

    Citation: Systematic Reviews 2018 7:245

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    The Correction to this article has been published in Systematic Reviews 2019 8:31

  15. Content type: Protocol

    Musculoskeletal injuries (MSI) represent more than half of all injuries in tactical populations (i.e., military service and public safety workers including police, firefighters, emergency medical services (EMS...

    Authors: Shawn D. Flanagan, Kellen T. Krajewski, Aaron M. Sinnott, Caleb D. Johnson, Shawn R. Eagle, Alice D. LaGoy, Meaghan E. Beckner, Anne Z. Beethe, Rose Turner, Mita T. Lovalekar, Courtenay Dunn-Lewis, Chris Connaboy and Bradley C. Nindl

    Citation: Systematic Reviews 2018 7:244

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  16. Content type: Protocol

    In this article, conceptualization of well-being is a starting point. According to Diener, subjective well-being refers to all kinds of evaluation, both positive and negative, people make about their own lives...

    Authors: Viviane Cruvinel Di Castro, Janete Capel Hernandes, Mauro Elias Mendonça and Celmo Celeno Porto

    Citation: Systematic Reviews 2018 7:243

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  17. Content type: Methodology

    Systematic reviews, which assess the risk of bias in included studies, are increasingly used to develop environmental hazard assessments and public health guidelines. These research areas typically rely on evi...

    Authors: Lisa Bero, Nicholas Chartres, Joanna Diong, Alice Fabbri, Davina Ghersi, Juleen Lam, Agnes Lau, Sally McDonald, Barbara Mintzes, Patrice Sutton, Jessica Louise Turton and Tracey J. Woodruff

    Citation: Systematic Reviews 2018 7:242

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  18. Content type: Research

    Chronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME) is an illness characterised by profound and pervasive fatigue in addition to a heterogeneous constellation of symptoms. The aetiology of this cond...

    Authors: S. Du Preez, M. Corbitt, H. Cabanas, N. Eaton, D. Staines and S. Marshall-Gradisnik

    Citation: Systematic Reviews 2018 7:241

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  19. Content type: Protocol

    Measuring wellbeing has never been so important. With the rapid growth of workplace wellbeing interventions, determining their effectiveness is not only good science but also good practice. A wide variety of w...

    Authors: Rebecca J. Jarden, Margaret Sandham, Richard J. Siegert and Jane Koziol-McLain

    Citation: Systematic Reviews 2018 7:240

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  20. Content type: Research

    The impact of deworming on parasite load, nutritional status and other health outcomes of non-pregnant adolescent girls and adult women is uncertain.

    Authors: Elizabeth Tanjong Ghogomu, Shalini Suresh, Pura Rayco-Solon, Alomgir Hossain, Jessie McGowan, Juan Pablo Peña-Rosas and Vivian Welch

    Citation: Systematic Reviews 2018 7:239

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  21. Content type: Protocol

    Self-management interventions have been proposed as effective strategies to improve health and well-being and promote optimal coping in cancer survivors. Several reviews have shown benefits of self-management ...

    Authors: Colleen Ann Cuthbert, Haider H. Samawi, Brenda R. Hemmelgarn and Winson Y. Cheung

    Citation: Systematic Reviews 2018 7:238

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  22. Content type: Protocol

    Amyotrophic lateral sclerosis (ALS) is a highly progressive and debilitating neurodegenerative disease, which usually leads to the death of affected individuals within a few years after the onset of symptoms. ...

    Authors: Elmira Agah, Fatemeh Saleh, Hossein Sanjari Moghaddam, Amene Saghazadeh, Abbas Tafakhori and Nima Rezaei

    Citation: Systematic Reviews 2018 7:237

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  23. Content type: Protocol

    It is now more important than ever to equip paramedic students, the likely future managers and leaders of ambulance services, with the knowledge and skills of improvement science. Effective teaching requires a...

    Authors: Robin Pap, Louis Shabella, Alan J. Morrison, Paul M. Simpson and David M. Williams

    Citation: Systematic Reviews 2018 7:236

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  24. Content type: Protocol

    Internationally, tobacco smoking is a leading cause of mortality, morbidity and health inequality. In England, despite increasing awareness about importance of public health interventions to reduce smoking, ab...

    Authors: Tuba Saygın Avşar, Hugh McLeod and Louise Jackson

    Citation: Systematic Reviews 2018 7:235

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  25. Content type: Protocol

    Given the increasing burden of breast cancer in the low- and middle-income countries, cost-effective approaches are needed to improve the early detection of breast cancer in these continents. Global policies a...

    Authors: Adwoa Bemah Bonsu and Busisiwe Purity Ncama

    Citation: Systematic Reviews 2018 7:234

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  26. Content type: Protocol

    Ecological momentary assessments (EMAs) and ecological momentary interventions (EMIs) represent a novel approach for the assessment and delivery of psychological support to depressed patients in daily life. Be...

    Authors: Desirée Colombo, Azucena Garcia Palacios, Javier Fernandez Alvarez, Andrea Patané, Michelle Semonella, Pietro Cipresso, Marta Kwiatkowska, Giuseppe Riva and Cristina Botella

    Citation: Systematic Reviews 2018 7:233

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  27. Content type: Protocol

    Existing evidence on the association between exposure to bullying and sleep is limited and inconclusive. The aims of this planned systematic review and meta-analysis are therefore (1) to determine whether expo...

    Authors: Morten Birkeland Nielsen, Ståle Pallesen, Anette Harris and Ståle Valvatne Einarsen

    Citation: Systematic Reviews 2018 7:232

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  28. Content type: Protocol

    Stroke secondary prevention guidelines recommend medication prescription and adherence, active education and behavioural counselling regarding lifestyle risk factors. To impact on recurrent vascular events, po...

    Authors: Olive Lennon, Catherine Blake, Jo Booth, Alex Pollock and Maggie Lawrence

    Citation: Systematic Reviews 2018 7:231

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  29. Content type: Protocol

    Suicide is one of the leading causes of death among children and adolescents. Most studies about the burden and risk factors for suicide have been conducted in high-income countries. However, there is a dearth...

    Authors: Godfrey Zari Rukundo, Elizabeth Kemigisha, Moses Ocan, Wilson Adriko and Dickens Howard Akena

    Citation: Systematic Reviews 2018 7:230

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  30. Content type: Research

    The risk of developing cardiovascular disease can be directly correlated to one’s resting blood pressure (BP), age, and biological sex. Resting BP may be successfully reduced using handgrip exercise training, ...

    Authors: Danielle C. Bentley, Cindy H. Nguyen and Scott G. Thomas

    Citation: Systematic Reviews 2018 7:229

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  31. Content type: Protocol

    The worldwide incidence and prevalence of diabetes mellitus (DM) are increasing. DM has a high social and economic burden due to its complications and associated disorders. Peripheral arterial disease (PAD) is...

    Authors: Carolina Dutra Queiroz Flumignan, Fábio Cabral Freitas Amaral, Ronald Luiz Gomes Flumignan, Vladimir Tonello Vasconcelos, Gabriela Araújo Attie, Raul Muffato Daolio, Henrique Jorge Guedes-Neto, Jorge Eduardo de Amorim, José Carlos Costa Baptista-Silva and Luis Carlos Uta Nakano

    Citation: Systematic Reviews 2018 7:228

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  32. Content type: Research

    Within increasingly constrained school timetables, interventions that integrate academic and health education to reduce substance use and violence may hold promise as a category of intervention that can positi...

    Authors: Tara Tancred, Sara Paparini, G. J. Melendez-Torres, Adam Fletcher, James Thomas, Rona Campbell and Chris Bonell

    Citation: Systematic Reviews 2018 7:227

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  33. Content type: Protocol

    Acute myocardial infarction (MI) remains one of the leading causes of death worldwide with no curative therapy available. Stem cell therapies have been gaining interest as a means to repair the cardiac tissue ...

    Authors: Kashif Khan, Karina Gasbarrino, Ibtisam Mahmoud, Georges Makhoul, Bin Yu, Line Dufresne, Stella S. Daskalopoulou, Adel Schwertani and Renzo Cecere

    Citation: Systematic Reviews 2018 7:225

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  34. Content type: Protocol

    A growing number of postdoctoral scholars are following diverse career paths that require broad skill sets to ensure success. Yet, most postdoctoral professional learning and development initiatives are intend...

    Authors: Lorelli Nowell, K. Alix Hayden, Carol Berenson, Natasha Kenny, Nancy Chick and Carolyn Emery

    Citation: Systematic Reviews 2018 7:224

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  35. Content type: Protocol

    Depression and non-communicable diseases (NCDs) account for a growing burden on health systems in low- and middle-income countries (LMICs). Depression is generally associated with the outcomes of NCDs and is a...

    Authors: Michael Udedi, Brian Pence, Felix Kauye and Adamson S. Muula

    Citation: Systematic Reviews 2018 7:223

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  36. Content type: Protocol

    Peripheral neuropathies are a common complication in patients with diabetes. Changes in nerve function and central pain processing can be quantified by assessing pain thresholds and pain modulation mechanisms.

    Authors: Eva Sierra-Silvestre, Leanne Bisset and Michel W. Coppieters

    Citation: Systematic Reviews 2018 7:222

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  37. Content type: Protocol

    Each year, infection with Plasmodium causes millions of clinical cases of malaria and hundreds of thousands of deaths. Resistance to different antimalarial medications continues to develop and spread, threatening...

    Authors: Rebekah Burrow, Thomas R. Fanshawe and Georgina S. Humphreys

    Citation: Systematic Reviews 2018 7:221

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  38. Content type: Protocol

    Key populations who bear a disproportionate burden of HIV, including female sex workers, men who have sex with men, people who use drugs, transgender people, and incarcerated populations, have been understudie...

    Authors: Amrita Rao, Sheree Schwartz, Keith Sabin, Tisha Wheeler, Jinkou Zhao, James Hargreaves and Stefan Baral

    Citation: Systematic Reviews 2018 7:220

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  39. Content type: Protocol

    Fetal growth restriction (FGR) is a complication of pregnancy associated with major neonatal morbidity and commonly diagnosed at birth based on birth weight below the 5th or the 10th centile. There is no conse...

    Authors: Cédric Gasse, Kim Paquette, Suzanne Demers, Stéphanie Roberge, Emmanuel Bujold and Amélie Boutin

    Citation: Systematic Reviews 2018 7:219

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  40. Content type: Research

    With over 230 million surgical procedures performed annually worldwide, better application of evidence in anesthesia and perioperative medicine may reduce widespread variation in clinical practice and improve ...

    Authors: Sylvain Boet, Nicole Etherington, David Nicola, Andrew Beck, Susan Bragg, Ian D. Carrigan, Sarah Larrigan, Cassandra T. Mendonca, Isaac Miao, Tatyana Postonogova, Benjamin Walker, José De Wit, Karim Mohamed, Nadia Balaa, Manoj Mathew Lalu, Daniel I McIsaac…

    Citation: Systematic Reviews 2018 7:218

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  41. Content type: Protocol

    Research partnership approaches, in which researchers and stakeholders work together collaboratively on a research project, are an important component of research, knowledge translation, and implementation. De...

    Authors: Femke Hoekstra, Kelly J. Mrklas, Kathryn M. Sibley, Tram Nguyen, Mathew Vis-Dunbar, Christine J. Neilson, Leah K. Crockett, Heather L. Gainforth and Ian D. Graham

    Citation: Systematic Reviews 2018 7:217

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  42. Content type: Protocol

    Blood cultures are an integral part of the diagnosis of bacteremia in unwell patients. The treatment of bacteremia involves the rapid and accurate identification of the causative agent grown from the blood cul...

    Authors: J. A. Hughes, C. J. Cabilan, Julian Williams, Mercedes Ray and Fiona Coyer

    Citation: Systematic Reviews 2018 7:216

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  43. Content type: Protocol

    Studies suggest that the Patient-Centred Medical Home (PCMH) model of primary care is more effective than standard care for improving clinical outcomes in patients with chronic diseases (non-communicable disea...

    Authors: James Rufus John, Shima Ghassempour, Federico Girosi and Evan Atlantis

    Citation: Systematic Reviews 2018 7:215

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  44. Content type: Protocol

    The 20–70% participation of diabetes patients in lifestyle interventions (LSI) worldwide seems to be rather sub-optimal, in spite of all intents of such interventions to delay further progress of the disease. ...

    Authors: Charalabos-Markos Dintsios, Nadja Chernyak, Benjamin Grehl and Andrea Icks

    Citation: Systematic Reviews 2018 7:214

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  45. Content type: Research

    Currently, there is a lack of guidelines for the use of short-acting bronchodilators (SABD) in people admitted to hospital for acute exacerbation of chronic obstructive pulmonary disease (AECOPD), despite rout...

    Authors: Zoe A. Kopsaftis, Nur S. Sulaiman, Oliver D. Mountain, Kristin V. Carson-Chahhoud, Paddy A. Phillips and Brian J. Smith

    Citation: Systematic Reviews 2018 7:213

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  46. Content type: Protocol

    Bariatric surgery results in substantial medical and economic benefits; however, independent studies typically report high patient preoperative attrition rates. Studies have identified individual characteristi...

    Authors: Tamasin Taylor, Ofa Dewes, Nalei Taufa, Wendy Wrapson and Richard Siegert

    Citation: Systematic Reviews 2018 7:212

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  47. Content type: Research

    The objective of the review was to synthesize evidence of barriers and facilitators to the integration of mental health services into PHC from existing literature. The structure of the review was guided by the...

    Authors: Edith K. Wakida, Zohray M. Talib, Dickens Akena, Elialilia S. Okello, Alison Kinengyere, Arnold Mindra and Celestino Obua

    Citation: Systematic Reviews 2018 7:211

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  48. Content type: Protocol

    In the long term, smoking cessation can decrease the risk of cancer, stroke, and heart attacks and improve overall survival. The aim of the proposed umbrella review is to summarize existing systematic reviews ...

    Authors: Alemu S. Melka, Catherine L. Chojenta, Elizabeth G. Holliday and Deborah J. Loxton

    Citation: Systematic Reviews 2018 7:210

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  49. Content type: Protocol

    Although documentation of harm towards children and young people has existed for centuries, it was not until the 1960s that it became a specific focus for health professionals. Since that time, the importance ...

    Authors: Jan Pringle, Ross Whitehead, Dona Milne, Eileen Scott and John McAteer

    Citation: Systematic Reviews 2018 7:207

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