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  1. Experiential peers are increasingly involved in the development and delivery of interventions for individuals who are engaged in delinquent behavior. Experiential peer support, which is the provision of suppor...

    Authors: Margriet Lenkens, Frank J. van Lenthe, Loïs Schenk, Tessa Magnée, Miranda Sentse, Sabine Severiens, Godfried Engbersen and Gera E. Nagelhout

    Citation: Systematic Reviews 2019 8:119

    Content type: Protocol

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  2. Due to a growing reliance on mobile phone technology and decreasing mobile phone costs, the use of mobile phones is on the rise, especially among the youth population. Young people are responsive and enthusias...

    Authors: Anam Feroz, Farina Abrejo, Sumera Aziz Ali, Rozina Nuruddin and Sarah Saleem

    Citation: Systematic Reviews 2019 8:117

    Content type: Protocol

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  3. Polycystic ovary syndrome (PCOS) is the most common endocrinopathy, affecting 4–12% of reproductive-aged women. Women with PCOS often exhibit many metabolic abnormalities that are associated with an increased ...

    Authors: Amie Woodward, Markos Klonizakis, Ian Lahart, Anouska Carter, Caroline Dalton, Mostafa Metwally and David Broom

    Citation: Systematic Reviews 2019 8:116

    Content type: Protocol

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  4. The lifetime risk of suicide in patients with substance use disorder is five to ten times the risk in the general population. Critically, up to 19% of patients continue to think about and attempt suicide even ...

    Authors: S. Espinet, T. Corrin, D. Baliunas, L. Quilty, L. Zawertailo, S. J. Rizvi, W. deRuiter, S. Bonato, V. De Luca, S. Kennedy and P. Selby

    Citation: Systematic Reviews 2019 8:115

    Content type: Protocol

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  5. Despite a considerable amount of epidemiological research for identification of risk factors involved in the development of colorectal cancer, the current understanding of the etiology of this disease remains ...

    Authors: Amal Idrissi Janati, Igor Karp, Hisham Sabri and Elham Emami

    Citation: Systematic Reviews 2019 8:114

    Content type: Protocol

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  6. Recent studies have observed low levels of physical activity in children and adolescents worldwide. Physical activity interventions are increasingly carried out to counteract this development. The school envir...

    Authors: Yolanda Demetriou, Anne K. Reimers, Marianna Alesi, Lidia Scifo, Carla Chicau Borrego, Diogo Monteiro and Anne Kelso

    Citation: Systematic Reviews 2019 8:113

    Content type: Protocol

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  7. Despite policies for universal HIV testing and treatment (UTT) regardless of CD4 count, there are still 1.8 million new HIV infections and 1 million AIDS-related deaths annually. The UNAIDS 90-90-90 goals targ...

    Authors: Dylan Green, Brenda Kharono, Diana M. Tordoff, Adam Akullian, Anna Bershteyn, Michelle Morrison, Geoff Garnett, Ann Duerr and Paul Drain

    Citation: Systematic Reviews 2019 8:110

    Content type: Protocol

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  8. Acute myeloid leukaemia is the most common type of acute leukaemia in the world. Thus, the study of genetic alterations, such as single-nucleotide polymorphisms (SNPs), has contributed to a better understandin...

    Authors: Taynah Cascaes Puty, Jonathan Souza Sarraf, Tabata Cristina Do Carmo Almeida, Valter Cordeiro Barbosa Filho, Luis Eduardo Werneck de Carvalho, Fernando Luiz Affonso Fonseca and Fernando Adami

    Citation: Systematic Reviews 2019 8:109

    Content type: Protocol

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  9. Schools can play a vital role in the resettlement of refugee children and their families. Yet, the body of research examining school environmental factors that support the mental health and acculturation of re...

    Authors: Deserae Horswood, Jess Baker, Mina Fazel, Susan Rees, Linda Heslop and Derrick Silove

    Citation: Systematic Reviews 2019 8:107

    Content type: Protocol

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  10. Following publication of the original article [1], the authors reported an error in Fig. 4 in the PDF version. Figure 4 is the duplicate image of Fig. 3 and the correct figure is missing. The authors would lik...

    Authors: Mapa Mudiyanselage Prabhath Nishantha Piyasena, Gudlavalleti Venkata S. Murthy, Jennifer L. Y. Yip, Clare Gilbert, Tunde Peto, Iris Gordon, Suwin Hewage and Sureshkumar Kamalakannan

    Citation: Systematic Reviews 2019 8:106

    Content type: Correction

    Published on:

    The original article was published in Systematic Reviews 2018 7:182

  11. The main objective of this review is to assess the effects of aerobic, resistance, and meditative movement exercise on sleep quality in patients with unipolar depression. A secondary goal is to ascertain the e...

    Authors: Gavin Brupbacher, Heike Gerger, Monika Wechsler, Thea Zander-Schellenberg, Doris Straus, Hildburg Porschke, Markus Gerber, Roland von Känel and Arno Schmidt-Trucksäss

    Citation: Systematic Reviews 2019 8:105

    Content type: Protocol

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  12. Recent estimates suggest that one in ten young people worldwide experiences a diagnosable mental health disorder, with many more suffering subsyndromal levels of psychological distress. As young people spend m...

    Authors: Thomas King and Mina Fazel

    Citation: Systematic Reviews 2019 8:104

    Content type: Protocol

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  13. A child’s risk of dying is highest in the neonatal period, i.e. the first 28 days of life. Newborn death accounts for nearly half of under-five death. More than 80% of newborn deaths are the result of preventa...

    Authors: Tesfalidet Tekelab, Mohammed Akibu, Negash Tagesse, Temesgen Tilhaun, Yosef Yohanes and Smriti Nepal

    Citation: Systematic Reviews 2019 8:103

    Content type: Protocol

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  14. Rare cancers comprise almost a quarter of all cancers in Europe, and patients generally have poorer outcomes than those suffering from more common cancers. This is attributed in part to a general lack of knowl...

    Authors: Catherine Bell, Katie Kerr, Kerry Moore, Charlene McShane, Lesley Anderson, Amy Jayne McKnight and Helen McAneney

    Citation: Systematic Reviews 2019 8:102

    Content type: Protocol

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  15. Aerobic exercise programs have been used for various health conditions, including musculoskeletal disorders. However, the literature is still limited regarding the effect of aerobic exercise on pain and disabi...

    Authors: Irlei dos Santos, Adriana Claudia Lunardi, Naiane Teixeira Bastos de Oliveira, Matheus Oliveira de Almeida and Leonardo Oliveira Pena Costa

    Citation: Systematic Reviews 2019 8:101

    Content type: Protocol

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  16. Diabetes is a chronic medical condition that requires patients to be actively engaged in intensive self-management to achieve optimal clinical outcomes. Unfortunately, individuals who are experiencing homeless...

    Authors: David J. T. Campbell, Rachel B. Campbell, Carolyn Ziegler, Kerry A. McBrien, Stephen W. Hwang and Gillian L. Booth

    Citation: Systematic Reviews 2019 8:100

    Content type: Protocol

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  17. Cerebral venous thrombosis causes disability from venous infarct and hemorrhage and potential mortality. Anticoagulation improves survival and disability outcomes, yet direct oral anticoagulants are currently ...

    Authors: Gauruv Bose, Justin Graveline, Vignan Yogendrakumar, Dean Fergusson and Dar Dowlatshahi

    Citation: Systematic Reviews 2019 8:99

    Content type: Protocol

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  18. The global prevalence of diabetes mellitus is nearly 9%, with an upward trend in type 2 and gestational diabetes mellitus (T2DM/GDM). Evidence shows that vulnerable groups are affected disproportionally. There...

    Authors: Jessica Breuing, Christine Graf, Annika Lena Neuhaus, Simone Heß, Lena Lütkemeier, Fabiola Haas, Mark Spiller and Dawid Pieper

    Citation: Systematic Reviews 2019 8:98

    Content type: Protocol

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  19. With healthcare striving to shift to a more person-centered delivery model, patient and family involvement must have a bigger role in shaping this. While many initiatives involving patients and family members ...

    Authors: Tamara L. McCarron, Karen Moffat, Gloria Wilkinson, Sandra Zelinsky, Jamie M. Boyd, Deborah White, Derek Hassay, Diane L. Lorenzetti, Nancy J. Marlett and Thomas Noseworthy

    Citation: Systematic Reviews 2019 8:97

    Content type: Research

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  20. This study aimed at applying the restricted mean survival time difference (rmstD) as an absolute outcome measure in a network meta-analysis and comparing the results with those obtained using hazard ratios (HR...

    Authors: C. Petit, P. Blanchard, JP. Pignon and B. Lueza

    Citation: Systematic Reviews 2019 8:96

    Content type: Methodology

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  21. Development of fistula-in-ano following incision and drainage (I&D) of anorectal abscesses occurs in over 30% of patients. It is associated with significant patient morbidity and societal cost. The use of anti...

    Authors: Laura Baker, Lara Williams, Remington Winter, Caitlin Cahill, Alexandra Davis and Dean Fergusson

    Citation: Systematic Reviews 2019 8:95

    Content type: Protocol

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  22. Efforts to improve health equity should be informed by the best available evidence. However, equity-related research is inconsistently indexed, and uses a variety of terms to describe key concepts, making it d...

    Authors: Jamie Hosking, Alexandra Macmillan, Rhys Jones, Shanthi Ameratunga and Alistair Woodward

    Citation: Systematic Reviews 2019 8:94

    Content type: Methodology

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  23. Low back pain is the greatest contributor to the global burden of disease and can result in work disability. Previous literature has examined the influence of personal factors, the healthcare system, workplace...

    Authors: Michael Di Donato, Ross Iles, Tyler Lane and Alex Collie

    Citation: Systematic Reviews 2019 8:92

    Content type: Protocol

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  24. Despite the introduction of rapid response systems and early warning scores, clinical deterioration that is not recognised or responded to early enough prevails in acute care areas. One intervention that aims ...

    Authors: Aidín McKinney, Donna Fitzsimons, Bronagh Blackwood and Jennifer McGaughey

    Citation: Systematic Reviews 2019 8:91

    Content type: Protocol

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  25. Before implementing healthcare interventions, clinicians need to weigh the beneficial and adverse effects of interventions. However, a large body of evidence has demonstrated that seeking and reporting of adve...

    Authors: Pauline A. J. Steegmans, Shandra Bipat and Reint A. Meursinge Reynders

    Citation: Systematic Reviews 2019 8:89

    Content type: Protocol

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  26. Opioids are routinely used to treat a variety of chronic conditions associated with pain. However, they are a class of medications with a significant potential for adverse health effects, with and without misu...

    Authors: Jean Deschamps, James Gilbertson, Sebastian Straube, Kathryn Dong, Frank P. MacMaster, Christina Korownyk, Lori Montgomery, Ryan Mahaffey, James Downar, Hance Clarke, John Muscedere, Katherine Rittenbach, Robin Featherstone, Meghan Sebastianski, Ben Vandermeer, Deborah Lynam…

    Citation: Systematic Reviews 2019 8:88

    Content type: Protocol

    Published on:

  27. Self-harm and suicide have been identified as serious public health problems in children, adolescents, and young people across the world. Suicide is a major cause of mortality in this population and is commonl...

    Authors: Isobel Marion Harris, Sophie Beese and David Moore

    Citation: Systematic Reviews 2019 8:87

    Content type: Protocol

    Published on:

  28. Many of the adverse outcomes experienced by mothers and babies are directly related to the health of the woman prior to pregnancy. This preconception period is a unique window of opportunity when women are oft...

    Authors: Loretta M. Musgrave, Caroline S. E. Homer, Nathalie V. Kizirian and Adrienne Gordon

    Citation: Systematic Reviews 2019 8:86

    Content type: Protocol

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  29. Collagen cross-linking (CXL) is an evolving procedure that enhances the biomechanical rigidity of the cornea and can slow or halt ectatic disease. CXL requires delivery of 5.4 J/cm2 of ultraviolet A (UVA) radiati...

    Authors: Siddharth Nath, Carl Shen, Alex Koziarz and Laura Banfield

    Citation: Systematic Reviews 2019 8:85

    Content type: Protocol

    Published on:

  30. Healthcare resources are limited and unnecessary, and inappropriate emergency department use is now a highly visible healthcare priority. Individuals visiting the emergency department for mental health-related...

    Authors: Amanda Digel Vandyk, Mark Kaluzienski, Catherine Goldie, Yehudis Stokes, Amanda Ross-White, Jeremy Kronick, Matthew Gilmour, Colleen MacPhee and Ian D. Graham

    Citation: Systematic Reviews 2019 8:84

    Content type: Protocol

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  31. The majority of children receiving care in the emergency department (ED) are discharged home, making discharge communication a key component of quality emergency care. Parents must have the knowledge and skill...

    Authors: Janet A. Curran, Allyson J. Gallant, Roger Zemek, Amanda S. Newton, Mona Jabbour, Jill Chorney, Andrea Murphy, Lisa Hartling, Kate MacWilliams, Amy Plint, Shannon MacPhee, Andrea Bishop and Samuel G. Campbell

    Citation: Systematic Reviews 2019 8:83

    Content type: Research

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  32. Fever and neutropenia (FN) is a common complication of chemotherapy for cancer. Prompt empiric broad-spectrum antibiotic therapy in FN is typically considered standard of care, but the definition of prompt is ...

    Authors: Christa Koenig, Jess Morgan, Roland A. Ammann, Lillian Sung and Bob Phillips

    Citation: Systematic Reviews 2019 8:82

    Content type: Protocol

    Published on:

  33. Age at the onset of menopause is the most important determinant of women’s future health outcomes. While the basic mechanisms contributing to the onset of menopause are still not fully understood, age at menop...

    Authors: Mansoureh Yazdkhasti, Zahra Mehdizadeh Tourzani, Nasibeh Roozbeh, Vajiheh Hasanpour, Sara Esmaelzadeh Saeieh and Fatemeh Abdi

    Citation: Systematic Reviews 2019 8:80

    Content type: Protocol

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  34. Domestic violence (DV) during pregnancy is recognized as a global health problem associated with serious health consequences for both the mother and her baby. Several interventions aimed at addressing DV aroun...

    Authors: Diksha Sapkota, Kathleen Baird, Amornrat Saito and Debra Anderson

    Citation: Systematic Reviews 2019 8:79

    Content type: Research

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  35. Waiting lists should be managed as fairly as possible to ensure that patients with greater or more urgent needs receive services first. Patient prioritization refers to the process of ranking referrals in a ce...

    Authors: Julien Déry, Angel Ruiz, François Routhier, Marie-Pierre Gagnon, André Côté, Daoud Ait-Kadi, Valérie Bélanger, Simon Deslauriers and Marie-Eve Lamontagne

    Citation: Systematic Reviews 2019 8:78

    Content type: Protocol

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  36. The need for specific services for young people is being widely recognized to address their unique and complex health needs. Growing evidence in integrated health services shows promise in improving the effici...

    Authors: Anuja Pandey, Aswathikutty Gireesh and Russell Viner

    Citation: Systematic Reviews 2019 8:77

    Content type: Protocol

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  37. Drug-resistant epilepsy negatively impacts the quality of life and is associated with increased morbidity and mortality and high costs to the healthcare system. Cannabis-based treatments may be effective in re...

    Authors: Jesse Elliott, Bláthnaid McCoy, Tammy Clifford, Beth K. Potter, Becky Skidmore, George A. Wells and Doug Coyle

    Citation: Systematic Reviews 2019 8:75

    Content type: Protocol

    Published on:

  38. For women seeking permanent contraception, there are a variety of options available including surgical techniques such as tubal ligation or bilateral salpingectomy, in-clinic procedures such as hysteroscopic t...

    Authors: Rebecca Gormley, Brian Vickers and Wendy V. Norman

    Citation: Systematic Reviews 2019 8:74

    Content type: Protocol

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  39. Liver cirrhosis represents a substantial global burden in terms of morbidity and mortality. Observational studies have reported an increased risk of death with low circulating 25-hydroxyvitamin D concentration...

    Authors: Désirée Völker, Frank Grünhage, Stefan Wagenpfeil, Frank Lammert and Caroline S. Stokes

    Citation: Systematic Reviews 2019 8:73

    Content type: Protocol

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  40. Suicide is an emergency psychiatric problem that needs an urgent intervention. Ethiopia, as a nation, has been experiencing high burden of suicide. Cultural taboo, stigma, and criticism associated with suicida...

    Authors: Berhanu Boru Bifftu, Berihun Assefa Dachew, Bewket Tadesse Tiruneh and Yonas Deressa Guracho

    Citation: Systematic Reviews 2019 8:72

    Content type: Protocol

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  41. Depression is common in patients with coronary artery disease (CAD) and is associated with poorer outcomes and higher costs. Several randomised controlled trials (RCTs) targeting depression, of various modalit...

    Authors: Frank Doyle, Kenneth Freedland, Robert Carney, Peter de Jonge, Chris Dickens, Susanne Pedersen, Jan Sorensen and Martin Dempster

    Citation: Systematic Reviews 2019 8:71

    Content type: Protocol

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  42. Approximately 50% of all youth-onset type 2 diabetes mellitus (T2DM) in Canada occurs in Indigenous children. In adults, cardiovascular disease is one of the leading causes of mortality in First Nations commun...

    Authors: Rebecca Crawford, E. Danielle Sims, Kuan-Wen Wang, Michael Youssef, Ajantha Nadarajah, Angelica Rivas, Laura Banfield, Lehana Thabane and M. Constantine Samaan

    Citation: Systematic Reviews 2019 8:69

    Content type: Protocol

    Published on:

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