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  1. In April 2005, researchers based at the Medical Research Council Clinical Trials Unit, set out to involve women affected by cervical cancer in a systematic review and meta-analysis of individual patient data t...

    Authors: Claire L Vale, Jayne F Tierney, Nicolette Spera, Andrea Whelan, Alison Nightingale and Bec Hanley
    Citation: Systematic Reviews 2012 1:23
  2. There is a significant public health burden associated with substance use in Canada. The early detection and/or treatment of risky substance use has the potential to dramatically improve outcomes for those who...

    Authors: Matthew M Young, Adrienne Stevens, Amy Porath-Waller, Tyler Pirie, Chantelle Garritty, Becky Skidmore, Lucy Turner, Cheryl Arratoon, Nancy Haley, Karen Leslie, Rhoda Reardon, Beth Sproule, Jeremy Grimshaw and David Moher
    Citation: Systematic Reviews 2012 1:22
  3. Obstructive sleep apnea is a relatively common disorder that can lead to lost productivity and cardiovascular disease. The form of positive airway treatment that should be offered is unclear.

    Authors: Stanley Ip, Carolyn D'Ambrosio, Kamal Patel, Ndidiamaka Obadan, Georgios D Kitsios, Mei Chung and Ethan M Balk
    Citation: Systematic Reviews 2012 1:20
  4. Over the past few years, information retrieval has become more and more professionalized, and information specialists are considered full members of a research team conducting systematic reviews. Research grou...

    Authors: Elke Hausner, Siw Waffenschmidt, Thomas Kaiser and Michael Simon
    Citation: Systematic Reviews 2012 1:19
  5. In meta-regression, as the number of trials in the analyses decreases, the risk of false positives or false negatives increases. This is partly due to the assumption of normality that may not hold in small sam...

    Authors: Joel J Gagnier, David Moher, Heather Boon, Claire Bombardier and Joseph Beyene
    Citation: Systematic Reviews 2012 1:18
  6. Mild traumatic brain injury (MTBI) is a major public-health concern and represents 70-90% of all treated traumatic brain injuries. The last best-evidence synthesis, conducted by the WHO Collaborating Centre fo...

    Authors: Carol Cancelliere, J David Cassidy, Pierre Côté, Cesar A Hincapié, Jan Hartvigsen, Linda J Carroll, Connie Marras, Eleanor Boyle, Vicki Kristman, Ryan Hung, Britt-Marie Stålnacke, Peter Rumney, Victor Coronado, Lena W Holm, Jörgen Borg, Catharina Nygren-de Boussard…
    Citation: Systematic Reviews 2012 1:17
  7. There is growing evidence of the impact of overweight and obesity on short- and long-term functioning, health and well-being. Internationally, childhood obesity rates continue to rise in some countries (for ex...

    Authors: Clare L Bambra, Frances C Hillier, Helen J Moore and Carolyn D Summerbell
    Citation: Systematic Reviews 2012 1:16
  8. Systematic reviews have become increasingly critical to informing healthcare policy; however, they remain a time-consuming and labor-intensive activity. The extraction of data from constituent studies comprise...

    Authors: Stanley Ip, Nira Hadar, Sarah Keefe, Christopher Parkin, Ramon Iovin, Ethan M Balk and Joseph Lau
    Citation: Systematic Reviews 2012 1:15
  9. Several systematic reviews and meta-analyses populate the literature on the effectiveness of laparoscopic surgery for colorectal cancer. The utility of this body of work is unclear. The objective of this study...

    Authors: Guillaume Martel, Suleena Duhaime, Jeffrey S Barkun, Robin P Boushey, Craig R Ramsay and Dean A Fergusson
    Citation: Systematic Reviews 2012 1:14
  10. Infection with the HIV and AIDS are leading causes of morbidity and mortality among women and children worldwide. Prevention of mother-to-child transmission of HIV (PMTCT) programs were developed to protect wo...

    Authors: Frederick LI Morfaw, Lehana Thabane, Lawrence CE Mbuagbaw and Philip N Nana
    Citation: Systematic Reviews 2012 1:13
  11. The aim of this individual participant data (IPD) meta-analysis is to assess whether the effects of repeat prenatal corticosteroid treatment given to women at risk of preterm birth to benefit their babies are ...

    Authors: Caroline A Crowther, Fariba Aghajafari, Lisa M Askie, Elizabeth V Asztalos, Peter Brocklehurst, Tanya K Bubner, Lex W Doyle, Sourabh Dutta, Thomas J Garite, Debra A Guinn, Mikko Hallman, Mary E Hannah, Pollyanna Hardy, Kimberly Maurel, Premasish Mazumder, Cindy McEvoy…
    Citation: Systematic Reviews 2012 1:12
  12. Hospital partnerships, mergers and cooperatives are arrangements frequently seen as a means of improving health service delivery. Many of the assumptions used in planning hospital cooperatives are not stated c...

    Authors: Thomas Rotter, Daniela Popa, Beatrice Riley, Tim Ellermann, Ulrike Ryll, Genc Burazeri, Piet Daemen, Guy Peeters and Helmut Brand
    Citation: Systematic Reviews 2012 1:11
  13. Rapid reviews have emerged as a streamlined approach to synthesizing evidence - typically for informing emergent decisions faced by decision makers in health care settings. Although there is growing use of rap...

    Authors: Sara Khangura, Kristin Konnyu, Rob Cushman, Jeremy Grimshaw and David Moher
    Citation: Systematic Reviews 2012 1:10
  14. Challenges exist when searching for diagnostic test accuracy (DTA) studies that include the design of DTA search strategies and selection of appropriate filters. This paper compares the performance of three ME...

    Authors: Rachel Mann and Simon M Gilbody
    Citation: Systematic Reviews 2012 1:9
  15. A common and potentially life-threatening complication of the treatment of childhood cancer is infection, which frequently presents as fever with neutropenia. The standard management of such episodes is the ex...

    Authors: Robert S Phillips, Alex J Sutton, Richard D Riley, Julia C Chisholm, Susan V Picton and Lesley A Stewart
    Citation: Systematic Reviews 2012 1:8
  16. Prospective registration of systematic reviews promotes transparency, helps reduce potential for bias and serves to avoid unintended duplication of reviews. Registration offers advantages to many stakeholders ...

    Authors: Lesley Stewart, David Moher and Paul Shekelle
    Citation: Systematic Reviews 2012 1:7
  17. Developing and registering protocols may seem like an added burden to systematic review investigators. This paper discusses benefits of protocol registration and debunks common misperceptions on the barriers o...

    Authors: Stephanie M Chang and Jean Slutsky
    Citation: Systematic Reviews 2012 1:4
  18. Clinical practice and public health guidelines are important tools for translating research findings into practice with the aim of assisting health practitioners as well as patients and consumers in health beh...

    Authors: Philip Van der Wees, Amir Qaseem, Minna Kaila, Guenter Ollenschlaeger and Richard Rosenfeld
    Citation: Systematic Reviews 2012 1:3
  19. Following publication of the PRISMA statement, the UK Centre for Reviews and Dissemination (CRD) at the University of York in England began to develop an international prospective register of systematic review...

    Authors: Alison Booth, Mike Clarke, Gordon Dooley, Davina Ghersi, David Moher, Mark Petticrew and Lesley Stewart
    Citation: Systematic Reviews 2012 1:2
  20. Welcome to a new age in publishing systematic reviews. We hope the launch of Systematic Reviews will resonate with a broad spectrum of readers interested in using them in a variety of ways, such as providing comp...

    Authors: David Moher, Lesley Stewart and Paul Shekelle
    Citation: Systematic Reviews 2012 1:1

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    Journal Impact Factor: 6.3
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