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Table 1 Bradford Hill criteria for evaluating the quality of studies

From: Impact of health system strengthening interventions on child survival in sub-Saharan Africa: a systematic review protocol

Hill’s criteria

Indicators for scoring

Y/N

Score

Strength of association

▪ 1. Is there a statistically significant causal effect?

 

1

▪ 2. Is the significance level very strong, indicated by a p value of less than 0.01?

 

1

▪ 3. Does the coefficient show a strong association, with coefficients equal to 2.0 or greater considered strong in this context? For instance, DiD HR ≥ 2.0 would suggest a strong association

 

1

Consistency

▪ Has the study examined multiple outcome measures related to the mortality of children under the age of five? These outcome measures include neonatal, infant, and post-infant mortality rates, in addition to overall U5 mortality

 

1

▪ Are there any patterns or similarities in the findings when comparing any two of these outcome measures?

 

1

Specificity

▪ Were the interventions designed to specifically reduce mortality among children under the age of five?

 

1

Temporality

▪ Was the implementation of interventions carried out before the impact on U5 mortality was observed?

 

1

Biological gradient

▪ Was the endline survey conducted after giving the interventions a year or more to mature?

 

1

Plausibility

▪ Is the relationship between U5 mortality and HSS interventions supported by existing literature?

 

1

▪ Have other observable factors in the model been chosen based on existing literature?

 

1

Coherence

▪ Is the interpretation of the findings in line with existing literature?

 

1

Experiment

▪ Is the design of the study appropriate to establish a causal effect?

 

1

▪ Are the methods employed suitable for establishing causal effect?

 

1

Analogy

▪ Based on the literature, did the study formulate a hypothesis to test the relationship between HSS interventions and child survival?

 

1

  1. U5 Under five