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Table 2 Characteristics of tools, checklists or journal standards (n = 12)

From: Methodological review of NMA bias concepts provides groundwork for the development of a list of concepts for potential inclusion in a new risk of bias tool for network meta-analysis (RoB NMA Tool)

First author, year of publication

# items

Type of instrument

Name

Type of assessment

Objective(s)

Research institute

Designed for a specific topic area

Domains within the tool

Rating of items and/or domains

Methods used to develop the tool

Guidance document

Ades 2012 [47]

42

Checklist

NICE DSU checklist

Reporting and methodological quality

Framework for determining whether a convincing argument has been made based on data presented

NICE

Standard meta-analysis, indirect comparisons and NMA

Definition of the decision problem, methods of analysis and presentation of results, issues specific to network synthesis, embedding the synthesis in a probabilistic cost-effectiveness analysis

3 domains: Definition of the decision problem, methods of analysis and presentation of results, issues specific to network synthesis, Embedding the synthesis in a probabilistic cost-effectiveness model

NR

No

Al Khalifah 2018 [48]

11

Checklist

Guide for appraising NMA evidence

Reporting and methodological quality

Users’ guide for pediatricians considering the application of the results of NMA

McMaster University

NMA

Credibility of NMA methods, certainty of NMA evidence, were results consistent across studies, how trustworthy are the indirect comparisons, applicability

NA

NR

No

Dias 2018 [49]

14

Checklist

 

Validity of NMAs

Introduce and discuss validity of NMAs

University of Bristol

NMA

Question formulation, trial inclusion/ exclusion and network connectivity; heterogeneity and bias management; reporting

NA

NR

No

Hutton 2015 [14]

32

Checklist

PRISMA NMA

Reporting

Present the NMA PRISMA extension and provide examples of good reporting

Ottawa Hospital Research Institute

Systematic reviews with NMA

Title, abstract, introduction, methods, results, discussion, funding

NA

Overview of reviews, Delphi, expert opinion

No

Jansen 2011 [50]

21

Checklist

Simplified checklist to assist decision makers in evaluating a reported NMA

Reporting and methodological quality

Provide guidance on the interpretation of indirect treatment comparisons and NMA to assist policymakers and health-care professionals in using its findings for decision making

ISPOR

NMA

Introduction, methods, results, discussion

NA

NR

No

Jansen 2014 [15]

26

Questionnaire

ISPOR

Reporting and methodological quality

Help decision makers assess the relevance and credibility of indirect treatment comparisons and NMA

ISPOR

NMA

Evidence base, analysis, reporting quality and transparency, interpretation, conflict of interest

3 levels: yes, no, cannot answer

Expert opinion, literature search, pilot testing

No

Kiefer 2015 [51]

9

Checklist

Checklist for evaluation of indirect comparisons and network meta-analyses

Reporting and methodological quality

Describe the underlying assumptions and methods used in indirect comparisons and NMA and explain what evaluation of such publications should include

Institute for Quality and Efficiency in Health Care

(IQWiG)

NMA

Methods, statistical analysis, reporting, limitations

NA

NA

No

Nikolakopoulou 2020 [23], Papakonstantinou 2020 [39], Salanti 2014 [40]

6

Framework

CINeMA

Confidence in results from NMA

Evaluate confidence in the results from network meta-analyses

Cochrane and the Campbell collaboration

NMA

Within-study bias, reporting bias, indirectness, imprecision, heterogeneity and incoherence

3 levels: no concerns, some concerns or major concerns (within); 4 levels: high, moderate, low, very low (summary)

Developed based on three previous studies, and participant feedback

Yes

Ortega 2014 [46]

20

Checklist

Checklist for critical appraisal of indirect comparisons

Reporting and methodological quality

Critical appraisal of indirect comparisons of drugs, considering clinical, methodological/statistical and quality aspects, applied in drug evaluation in the decision-making

Clinica Universidad de Navarra

Indirect comparisons

Quality, clinical aspects, methodology/statistics

3 levels: high, acceptable, low

Review of literature, group consensus, expert guidance

No

Page 2020 [25]

27

Checklist

PRISMA 2020 Statement

Reporting

Describe and justify changes made to the guideline

Monash University

Systematic reviews

Title, abstract, introduction, methods, results, discussion, other information

NA

Review, survey, expert meeting

Yes

  1. CINeMA Confidence in Network Meta-Analysis, DSU Decision Support Unit, GRADE-NMA Grading of Recommendations Assessment, Development and Evaluation for Network Meta-Analysis, ISPOR International Society for Pharmacoeconomics and Outcomes Research, NA not applicable, NICE National Institute for Health and Care Excellence, NR not reported, OQAQ Overview Quality Assessment Questionnaire, PRISMA Preferred Reporting Items for Systematic Reviews and Meta-Analyses