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Table 1 GRADE for the certainty of evidence

From: Dual antiplatelet management in the perioperative period: updated and expanded systematic review

Outcome

Study limitations

Consistency

Directness

Precision

Certainty of evidence

Holding DAPT for more than 2 days vs less than ≤ 2 days

 CABG surgery

  Bleeding is less

Serious limitations

Inconsistent

Direct

Imprecise

Low

  Transfusion is less

Serious limitations

Inconsistent

Direct

Imprecise

Low

  Re-exploration is less

Serious limitations

Inconsistent

Direct

Imprecise

Low

Holding DAPT vs continuing DAPT

 CABG surgery

  No difference in bleeding

Serious limitations

Inconsistent

Direct

Imprecise

Very low

  No difference in transfusions

Serious limitations

Inconsistent

Direct

Imprecise

Very low

  No difference in re-exploration

Serious limitations

Consistent

Direct

Imprecise

Very low

 Non-cardiac surgery

  Bleeding is less

Serious limitations

Inconsistent

Direct

Imprecise

Very low

  No difference in MACE/cardiac outcomes

Serious limitations

Consistent

Direct

Imprecise

Very low