From: Dual antiplatelet management in the perioperative period: updated and expanded systematic review
Outcome | Study limitations | Consistency | Directness | Precision | Certainty of evidence |
---|---|---|---|---|---|
Holding DAPT for more than 2 days vs less than ≤ 2 days | |||||
 CABG surgery | |||||
  Bleeding is less | Serious limitations | Inconsistent | Direct | Imprecise | Low |
  Transfusion is less | Serious limitations | Inconsistent | Direct | Imprecise | Low |
  Re-exploration is less | Serious limitations | Inconsistent | Direct | Imprecise | Low |
Holding DAPT vs continuing DAPT | |||||
 CABG surgery | |||||
  No difference in bleeding | Serious limitations | Inconsistent | Direct | Imprecise | Very low |
  No difference in transfusions | Serious limitations | Inconsistent | Direct | Imprecise | Very low |
  No difference in re-exploration | Serious limitations | Consistent | Direct | Imprecise | Very low |
 Non-cardiac surgery | |||||
  Bleeding is less | Serious limitations | Inconsistent | Direct | Imprecise | Very low |
  No difference in MACE/cardiac outcomes | Serious limitations | Consistent | Direct | Imprecise | Very low |