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Table 3 Findings from the eHealth studies

From: Gestational diabetes mellitus, follow-up of future maternal risk of cardiovascular disease and the use of eHealth technologies—a scoping review

Author

Year published

Country

Study design and GDM definition

Aim of study

Population

Intervention

Outcomes measured

Key findings

- Kim et al. [37]

- 2021

- South Korea

- Quasi-experimental study

- Exact diagnostic not specified, only stated that it is based on the result of oral glucose tolerance test between gestational weeks 24 and 28

- Developing and evaluating the efficacy of a self-management mobile virtual reality program for preventing T2DM in women with recent GDM

- 128 women with recent GDM and no visual, auditory or active disabilities

- Int.: 64. Con.: 64

- Control group not randomly assigned but selected after completing baseline measures for intervention group by matching for age, birth experience, type of birth, family history of T2DM, and breastfeeding status

-5.4% patient withdrawal

- Mobile virtual reality program with diet and exercise modules, laughter therapy, and neonatal first aid

- Control: written educational material

- Follow-up: 12 weeks

- Body weight, body fat, fasting glucose, and HbA1c

- Diabetes knowledge score

- Dietary habits

- Health promoting lifestyle score

- Parenting stress

- Significant differences between the groups for all four physiological variables, as well as dietary habits and health promoting lifestyle score

- No statistically significant differences for diabetes knowledge or parental stress

- Lim et al. [38]

- 2021

- Singapore

- RCT

- 2013 WHO/IADPSG criteria

- Examine the effectiveness of a smartphone app for restoring target weight postpartum in women with recent GDM

- 200 women with recent GDM

- Int.: 101.Con.: 99

- 9% lost to follow-up

- Smartphone app where participants could log weight, meals, activity and interact with health care professionals

- Control group: standard care, with dietary advice and OGTT 6 weeks postpartum and further follow-up based on results

- Follow-up: 4 months

- Primary: attainment of target weight 4 months postpartum (return to first trimester weight if BMI ≤ 23, or a minimum of 5% weight loss from first trimester weight if BMI ≥ 23

- Secondary: HbA1c, lipid profiles and other biomarkers, blood pressure, absolute weight loss, self-report calorie intake, health behavior, and emotional distress scores

- No significant group differences for primary outcome nor for serum biomarkers

- Self-reported calorie intake lower in intervention group, and higher health behavior score, but also higher level of emotional stress

- Potzel et al. [35]

- 2022

- Germany

- RCT

- Validated diagnosis of GDM according to German guidelines from 2014 (equivalent to 2013 WHO criteria)

- To evaluate the acceptability and effectiveness in improving CVD risk factors in women with recent GDM

- 66 women with GDM in last 3–18 months

- Int.: 33. Con.: 33.

- 18.2% drop-out

- iPhone app with modules on mental and emotional habits, physical activity, nutrition, and sleep. Possibilities for interaction with health care providers.

Control: standard care (leaflet with lifestyle advice for preventing diabetes)

- Follow-up: 6 months

- Primary: proportion of participants achieving ≥ 3 out of 5 Diabetes Prevention Program goals regarding physical activity, fiber and fat intake, and weight reduction/maintenance

- Secondary: glucose levels, insulin sensitivity, oxygen uptake, body fat, and psychosocial indices. Patients also rated app acceptability

- No significant group differences for primary or secondary outcomes

- 22 vs 11% in intervention and control group achieving primary outcome, but not statistically significant (p = 0.20)

- App was well accepted

- Peacock et al. [36]

- 2015

- Australia

- RCT

- Not specified

- Developing a program to support behavior changes in order to delay or prevent T2DM in women with a history of GDM and BMI > 25

- 31 women with a GDM diagnosis within the previous 6 to 24 months

- Int.: 16. Con.: 15

- 31% and 20% drop-out in intervention and control group respectively

- Pedometer program linked to web-based program where steps were logged and weekly goals generated. Also, 4 weeks nutrition coaching workshop

- Control: “wait-list group,” offered nutrition workshop after end of follow-up

Follow-up: 3 months

- Primary: weight loss

- Secondary: waist/hip circumference, diet quality, insulin sensitivity, body composition, physical activity, self-efficacy in eating behaviors

- Significant difference in weight loss: − 2.5 kg (1.4 SD) vs 0.0 kg (2.3 SD), p = 0.002

- For the secondary outcomes, there were significantly better results in intervention group for hip and waist circumference and self-efficacy in eating behaviors

  1. Abbreviations: HbA1c Glycated hemoglobin; T2DM Type 2 diabetes mellitus; GDM Gestational diabetes mellitus; BMI Body mass index, RCT Randomized controlled trial, Int. Intervention group, Con. Control group