Table 1 Summary of data analysis
From: Comparative efficacy of oral drugs for chronic radiation proctitis — a systematic review
Outcome or subgroup | Studies | Participants | Statistical method | Effect estimate |
|---|---|---|---|---|
1. Sucralfate | ||||
1.1 Overall diarrhoea score | 3 | 486 | Odds ratio (M-H, fixed, 95% CI) | 0.66 (0.40, 1.07) |
1.2 Bleeding | 3 | 486 | Odds ratio (M-H, fixed, 95% CI) | 0.81 (0.47, 1.41) |
1.3 High frequency | 2 | 364 | Odds ratio (M-H, fixed, 95% CI) | 0.73 (0.39, 1.36) |
2 Chinese medicine | ||||
2.1 High symptom score | 4 | 232 | Odds ratio (M-H, fixed, 95% CI) | 0.18 (0.10, 0.34) |
2.2 High KPS score | 1 | 55 | Mean difference (IV, random, 95% CI) | 0.24 (−3.89, 4.37) |
2.3 Haemoglobin | 1 | 55 | Mean difference (IV, fixed, 95% CI) | 4.82 (−2.14, 11.78) |
3 Dietary and supplementary treatments | ||||
3.1 Reduced bleeding | 2 | 80 | Mean difference (IV, random, 95% CI) | 6.02 (1.75, 10.30) |
3.2 Endoscopic evaluation | 1 | 70 | Odds ratio (M-H, fixed, 95% CI) | 3.89 (1.34, 11.25) |
3.3 BMI | 1 | 63 | Mean difference (IV, fixed, 95% CI) | −0.15 (−1.04, 0.74) |
4. Pentoxifylline and tocopherol | ||||
4.1 Relieved symptom | 1 | 30 | Odds ratio (M-H, fixed, 95% CI) | 5.00 (0.93, 26.79) |