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Table 1 Characteristics of the included studies

From: Tolvaptan for water retention in heart failure: a systematic review

Article IDs

Number of Included Studies

Number of Included participants

Treatment Group

Control Group

Tools for quality evaluation

Outcome measures

Yang CJ 2015(CN) [23]

8

13453

Tolvaptan

placebo

Jadad scale

①③

Wang CB 2017(CN) [15]

6

746

Tolvaptan

placebo or active controls

Cochrane risk of bias tool

①③④

Wu MY 2019(CN) [16]

12

5793

Tolvaptan

Placebo

Cochrane risk of bias tool

①②③④

Ma G 2018(CN) [17]

7

937

Tolvaptan Add-on therapy

placebo or active controls

Cochrane risk of bias tool

①③④

Xiong B 2015(CN) [18]

10

5574

Tolvaptan

placebo or active controls

Cochrane risk of bias tool

①③④

Huang WI 2018(CN) [22]

6

669

Tolvaptan

placebo or active controls

Jadad scale

①②④

Kinugawa K 2018(JP) [19]

14

5991

Tolvaptan Add-on therapy

placebo or active controls

Cochrane risk of bias tool

①②③

Luo XD 2020(CN) [21]

12

5577

Tolvaptan Add-on therapy

placebo or active controls

Cochrane risk of bias tool

①②③④

Alskaf.E.E 2016(the UK) [20]

8

5385

Tolvaptan

Placebo

Cochrane risk of bias tool

①②③④

  1. â‘ Serum sodium concentration
  2. ②Urine output
  3. ③Weight loss
  4. â‘ŁAll-cause mortality
  5. CN China, JP Japan