Table 8 Type of adverse effects sought and reported in the review

Tooth structures

12.8% (25/195)

Periodontal tissues

13.8% (27/195)

Intraoral (non-tooth or periodontal) tissues

2.6% (5/195)

Extraoral tissues (non-temporomandibular tissues)

0.5%(1/195)

Temporomandibular tissues and disorders

4.1% (8/195)

Undesired treatment results

22.1% (43/195)

Relapse and stability

18.5% (36/195)

Negative qualitative experiences by the patient or carer(s)

15.9% (31/195)

Appliance failure

7.7% (15/195)

Gastro-intestinal

0.5%(1/195)

Non-defined

1.0% (2/195)

Additional adverse effects^a

0.5%(1/195)