Table 4 Additional data extraction fields for the outcome of interest in study 2

Results

• Did the SR authors conduct GRADE assessments for the outcome of interest? (yes/no)

If the review authors did not use GRADE, extract the following:

• How do the authors define the outcome of interest and at what time point is it measured?

• What intervention and comparator are being investigated for the outcome of interest?

• What tools are used to measure the outcome of interest (i.e., specific scale, number of teeth)?

• If a meta-analysis was completed extract:

     ◦ The type of effect measure used by the authors

     ◦ The pooled effect estimate and 95% CI

     ◦ Screenshot of the forest plot

     ◦ If there is no forest plot, also extract the I² value and corresponding p-value

• If there was no meta-analysis extract:

     ◦ The included RCTs used to analyze the outcome of interest (extract first author name and reference number)

     ◦ The number of participants analyzed for the outcome of interest

     ◦ Verbatim quotation of the qualitative synthesis of the outcome of interest by the SR authors

     ◦ Any effect estimates provided for each of the included RCTs investigating the outcome of interest

• Was a minimally or partially contextualized approach used to assess imprecision?

• Results of the RoB assessment

• Is there evidence of serious or very serious indirectness? (yes/no)

     ◦ If yes, provide a rationale.

• Is there any reason to suspect publication bias? (yes/no)

     ◦ If yes, provide a rationale.

Conclusions

• Verbatim quotation of the SR conclusion statements pertaining to the outcome of interest from the SRs conclusion section

     ◦ If there is no conclusion section, this is to be extracted from the discussion section. If there is no conclusion outlined in the discussion, this is to be extracted from the abstract.

• Do the authors rely on a p-value to make their conclusions (e.g., p < 0.05)? (yes/no)

• Do the authors make any recommendations in their conclusion for the outcome of interest? (yes/no)

• Do the authors consider if there are any limitations to their findings in their conclusion (by means of a GRADE assessment or otherwise)? (yes/no)