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Table 1 Characteristics of the included studies for the meta-analysis

From: Prognostic significance of systemic immune-inflammation index in patients with nasopharyngeal carcinoma: a meta-analysis

First author

Year of publication

Patients (n)

Metastatic status

WHO histological type

AJCC stage

Cutoff value

Endpoints

Median follow-up (months)

Age (years)

Treatment

NOS score

Jiang

2017

327

Mixed

NA

I-IV (7th)

403.00

OS

38.3 (2–164.6)

50 (20–80)

Radiotherapy +/− chemotherapy

7

Oei

2018

585

Mixed

II/III

I-IV (7th)

527.20

OS/PFS/DMFS

63.3 (4.8–86.4)

49 (17–82)

IMRT

8

Lin

2019

243

Metastatic

I/II/III

NA

930.00

OS/PFS

77 (2–135)

48 (17–81)

Radiotherapy +/− chemotherapy

8

Feng

2020

417

Metastatic

NA

III-IV (8th)

488.90

OS/PFS

NA

47 (14–81)

Radiotherapy +/− chemotherapy

8

Zeng

2020

255

Mixed

I/II/III

I-IV (7th)

715.74

OS

33.5 (2.1–151.2)

51 (12–78)

Radiotherapy +/− chemotherapy, chemotherapy, untreated

6

Li

2021

342

Mixed

NA

I-IV (8th)

804.08

OS/PFS

66 (3–110)

49 (16-83)

IMRT, CCRT +/− induction, and/ or adjuvant chemotherapy

7

  1. Abbreviations: OS Overall survival, DMFS Distant metastasis-free survival, PFS Progression-free survival, WHO World Health Organization, AJCC intensity-modulated radiotherapy, NOS Newcastle–Ottawa scale, NA Not available, IMRT Intensity-modulated radiotherapy, CCRT Concurrent chemoradiotherapy