Table 4 MSC effect on diabetes parameters (Insulin TDD, HbA1c, C-peptide, and Adjusted HbA1c) in different follow-up periods

MSC therapy effect

Insulin TDD (U/kg/day)

3

− 0.226

− 0.851/0.398

0.477

53.1%

6^a

–

–

–

–

12

− 1.235

− 3.663/1.193

0.319

82.4%

HbA1c (%)

3

− 1.011

− 1.919/− 0.103

0.029

74.2%

6^a

–

–

–

–

12

− 1.715

− 2.386/− 1.045

0.000

00.0%

c-Peptide (ng/ml)

3

0.243

− 0.163/0.649

0.240

00.0%

6^a

–

–

–

–

12

1.234

0.612/1.856

0.000

00.0%

Adjusted HbA1c

3

− 1.337

− 2.296/− 0.377

0.006

74.8%

6^a

–

–

–

–

12

− 3.119

− 5.132/− 1.087

0.003

81.2%