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Table 1 Characteristics of the identified registers

From: Where to prospectively register a systematic review

Register

Specific to systematic reviews

Generic

PROSPERO

Research Registry

INPLASY

OSF Registries

protocols.io

Full name

International prospective register of systematic reviews

Research Registry - Registry of Systematic Reviews/Meta-Analyses

International Platform of Registered Systematic Review and Meta-analysis Protocols

OSF Preregistration

protocols.io

URL

crd.york.ac.uk/prospero/

researchregistry.com/browse-the-registry#registryofsystematicreviewsmeta-analyses/

inplasy.com/

cos.io/initiatives/prereg

protocols.io

Available since

2011

2015

2020

2019

2014

Costs

None

99 GBP per systematic review

New registration: 20.90 USD or 12 USD (reduced price for selected countries).

Update of registration: 8.90 USD (reduced price 4.90 USD).

None

None

Number of registration records as per 27 February 2021

> 100,000 (106,828)

>  1000 reviews (1051)

>  1000 (1446)

>  1000 (4152 when searching “systematic review”

>  100 (140 when searching “systematic review”)

Assessment of records (e.g., for completeness, eligibility)

Yes

Yes

Yes

No

No

Processing time (submission to publication)

No information

None (data curation takes place afterwards)

Max. 48 h

None

None

Fields/structure

28 mandatory fields, 12 optional fields

28 mandatory fields, 6 optional fields

24 mandatory fields, 9 optional fields

13 mandatory fields in OSF preregistration; 5 mandatory fields in Open-Ended-Registration

No given structure

Enables searching

Yes, text words, MeSH terms and many other characteristics

Yes, primary investigator, text words, title, and identifying number

Yes, text words and identifying number

Yes, text words only

Yes, text words only

Provides contact address of corresponding author

Yes

Yes

Yes

No

Not mandatory, but messages can be sent through protocols.io

Reminders to keep the entry up to date?

Yes

Unclear

No

No

Unclear

Information on review status (i.e., completed/published)

Yes

Link/Reference/DOI of full paper can be added once published

Yes

No

No

Restricted to reviews?

Yes, accepts only systematic reviews

Yes, accepts systematic reviews and meta-analyses

Yes, accepts systematic and scoping reviews

No, accepts all study designs

No, accepts all study designs

Restricted to field/discipline?

Health; but accepts also social care, welfare, public health, education, crime, justice, and international development if there is a direct health-related outcome

No

No

No

No

Version tracking

Yes

No

Yes

Yes

Yes

Unique identifying number

Yes

Yes

Yes

No

No

DOI

No

No

Yes

Yes

Yes

Section for submitting results

No

Yes, allows for uploading any data files

No

No, but can be linked to OSF project where results can be uploaded

No