Fig. 2

Univariate meta-regression analysis between changes in (1) mPAP, (2) PVR, (3) RAP, (4) CI, and all adverse events (Y). Only statistically significant relationships in table are plotted in this figure. mPAP, mean pulmonary artery pressure; PVR, pulmonary vascular resistance; RAP, right atrial pressure; CI, right ventricle cardiac output index. Each figure also shows the regression lines (bold straight lines) and their 95% confidence intervals (the thinner lines above and below the regression line represents the upper and lower limits). The size of the circles represents the importance of the study results in the regression estimates