Table 1: Summary of included papers
From: Detecting signs of deterioration in young patients with serious mental illness: a systematic review
Author and country | Design | Participants | Indicator of deterioration | Outcome measure | Main findings | NOS assessment score |
|---|---|---|---|---|---|---|
Cotton et al. [26] Australia | Cohort | 661 Aged 15–29 years Schizophrenia | Cognitive functioning (decline/stable) | Treatment reduction or discontinuation Number of admissions | Decline in cognitive functioning predicts a higher number of hospital admissions | Poor |
Gonzalez-Blanch et al. [27] Spain | Cohort | 63 Aged 15–25 First episode psychosis | Expressed emotion status (high/low) | Cannabis use | Cannabis use was significantly related to high expressed emotion | Poor |
Gunnell et al. [28] Sweden | Cohort | 186808 Aged 16 Serious mental illness diagnosis varied | Cognitive functioning (poor school performance) | Deaths by suicide | Poor school performance at aged 16 was not significantly associated with suicide risk | Good |
Lambert et al. [29] Australia | Cohort | 786 Aged 15–29 First-episode psychosis | Worsening cognitive functioning | Medication-adherence/refusal | Non-adherent patients had worse outcomes. More likely to be disengaged from services, not in remission of symptoms and have worse severity of illness. | Poor |
Linszen et al. [30] Netherlands | Cohort | 97 Aged 15–26 years Schizophrenia, schizoaffective disorders, schizophreniform disorders and other psychotic disorders | Expressed emotion status (high/low) | Relapse | Five times higher risk of relapse in those who experienced high expressed emotion | Poor |