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Table 5 Characteristics of cohort studies of exposures to vinyl chloride monomer (VCM)

From: Association between occupational exposures and sarcoma incidence and mortality: systematic review and meta-analysis

Author/year

Country

Years of employment

Years of follow-up

Study cohort

Reference cohort

Smulevich et al., 1988 [55]

Former Soviet Union

1939–1977

1939–1977

3232 workers (2195 men, 1037 women) with > 1-month employment of the vinyl chloride (VC) and polyvinyl chloride (PV) chemical plant

General population of the city where the plant was located

Ward et al., 2001 [56]

Italy, Norway, Sweden, UK

1940–1989

1955–1997

12,706 workers from 19 plants of VC, VCM and PVC production, with ≥ 1 year employment

Age and calendar period specific national incidence or mortality rates from the World Health Organization

Wong et al., 2002 [57]

Taiwan

1950–1992

1985–1997

3293 workers from 6 polyvinyl chloride polymerization factories employed ≥ 1

General Taiwanese male population

Mundt et al., 2017 [58]

US and Canada

1942–1972

1942–2013

9951 VC or PVC resin manufacture workers at 35 factories in the US and Canada employed for ≥ 1 year

General population

Fedeli et al., 2019 [59]

Italy

1956–1985

1973–2017

1658 workers employed in a VCM production and

polymerization facility in Porto Marghera (northeastern Italy)

1658 workers employed in a VCM production and

polymerization facility in Porto Marghera (northeastern Italy)

1658 male workers employed in VCM production and polymerization facility

General population