Anti-epileptic drug exposure during pregnancy and neonatal birth weight outcomes: protocol for a systematic review and meta-analysis

Table 1 Eligibility criteria to be included in the review (PICO)

(P)opulation	Pregnant women
(I)ntervention	Anti-epileptic drugs (AED) therapy
(C)omparison	WWOE on AED WWOE not on AED (general population) WWE not on AED WWE on AED (active comparisons)
(O)utcome	Primary outcomes: Birth weight outcomes (SGA, LBW, BW) Secondary outcomes: Head circumference, cephalization index, and birth length (height).

WWOE women without epilepsy, WWE women with epilepsy, AED anti-epileptic drug, SGA small for gestational age, LBW low birth weight, BW birth weight

ISSN: 2046-4053