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Table 4 Correlation analysis of lesion recurrence or progression with clinical and therapeutic factors

From: Diagnosis and treatment of Rosai-Dorfman disease of the spine: a systematic literature review

Clinical and therapeutic factors*

Recurrence and/or progression of spinal lesions

Yes

No

p value

Age (n = 54)

36.2 ± 21.8

34.1 ± 18.5

0.758

Focal lesion conditions (n = 51)

 Focally constrained

5(11.4%)

39(88.6%)

0.033#

 Focally concurrent

3(42.9%)

4(57.1%)

 

Involved organs (n = 33)

 Single

1(6.7%)

14(93.3%)

0.346

 Multiple

4(22.2%)

14(77.8%)

Treatment options (n = 54)

 Surgery

8(17.8%)

37(82.2%)

0.754

 Non-surgery

2(22.2%)

7(77.8%)

 

Surgical strategies (n = 45)

 Total resection

2(9.1%)

20(90.9%)

0.243

 Non-total resection

6(26.1%)

17(73.9%)

Non-surgery therapies (n = 54)

 Yes

4(28.6%)

10(71.4%)

0.261

 No

6(15.0%)

34(85.0%)

  1. Non-surgery therapies include radiotherapy, steroids and/or chemotherapy. Focally constrained lesions mean isolated lesions focally constrained to the dura, intrabony region, or intramedullary region. Focally concurrent lesions mean lesions invading multiple spinal components
  2. *Only data documented in the original literature were included
  3. #Statistically significant at p < 0.05, two-tailed Pearson’s chi-squared test