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Table 2 Antibiotic susceptibility profile in people with cystic fibrosis versus non cystic fibrosis bronchiectasis

From: Comparison of respiratory pathogen colonization and antimicrobial susceptibility in people with cystic fibrosis bronchiectasis versus non-cystic fibrosis bronchiectasis: a protocol for a systematic review

Data extracted by
Reference Author & year  
Citation  
Country/countries  
Institution/s  
Study design Clinical/microbiology study  
Observational study  
Clinical trial  
Case series with > 10 cases  
Case series with < 9 case  
Time period
Participants • CF bronchiectasis  
• Non CF bronchiectasis  
• Mixed  
• Other  
Study group (CF bronchiectasis) No.  
Age  
• Adults > 18 years  
• Children < 18 years  
• Mixed (not possible to separate)  
Sex  
AST method  
• AST definition  
• Ability to detect mutants  
• Advantages  
• Disadvantages  
Antibiotic susceptibility (S/I/R; MIC)
Microorganism Tobramycin Azythromycin Carbenicillin Ceftazidime Gentamycin Chloramphenicol Ciprofloxacin Colistin Minocycline
Staphylococcus aureus (MSSA)          
Staphylococcus aureus (MRSA)          
Pseudomonas aeruginosa          
Burkholderia cepacia complex          
Haemophilus influenzae          
Stenotrophomonas maltophilia          
Achromobacter xylosoxidans          
NTM          
Streptococcus          
Veillonella          
Others          
Inclusion/Exclusion criteria
Upper respiratory specimen
 Nasal specimen  
 Nasopharyngeal specimen  
 Oropharyngeal specimen  
 Other  
Lower respiratory specimen
 Sputum  
 Induced sputum  
 BAL  
 Lung aspirate  
 Other  
Antibiotic therapy
 Already on antibiotic(s)  
 Not on antibiotic(s)  
 Unclear  
Method of identifying species
 Culture  
 PCR  
 Other  
Biofilm detection
Antimicrobial resistance (Yes/No)
Remarks
Comparison group (non-CF bronchiectasis) No.  
Age  
• Adults > 18 years  
• Children < 18 years  
• Mixed (not possible to separate)  
Sex  
AST method  
• AST definition  
• Ability to detect mutants  
• Advantages  
• Disadvantages  
Antibiotic susceptibility (S/I/R; MIC)
Microorganism Piperacillin-tazobactam Amoxycillin Clarithromycin Ciprofloxacin Ceftazidime Cefuroxime Cefotaxime Flucloxacillin Tobramycin Amoxicillin-clavulanate
Haemophilus influenzae           
Pseudomonas aeruginosa           
Moraxella catarrhalis           
NTM
Staphylococcus aureus           
Streptococcus           
Veillonella           
Prevotella           
Others           
Inclusion/Exclusion criteria
Upper respiratory specimen
 Nasal specimen  
 Nasopharyngeal specimen  
 Oropharyngeal specimen  
 Other  
Lower respiratory specimen
 Sputum  
 Induced sputum  
 BAL  
 Lung aspirate  
 Other  
Antibiotic therapy
 Already on antibiotic(s)  
 Not on antibiotic(s)  
 Unclear  
Method of identifying species
 Culture  
 PCR  
 Other  
Biofilm detection
Antimicrobial resistance (Yes/No)
Remarks