Table 4 Non-anticholinergic adverse drug reactions to amitriptyline
System | Symptom |
|---|---|
Gastrointestinal tract | Sour or metallic taste Stomatitis Gastric irritation Nausea and vomiting |
Hypersensitivity reactions | Urticaria Angioedema Photosensitization Cholestatic jaundice Blood disorders such as eosinophilia Bone-marrow depression Thrombocytopenia Leucopenia Agranulocytosis |
Endocrine system | Testicular enlargement Gynecomastia Breast enlargement Galactorrhoea Sexual dysfunction Changes in blood sugar concentrations Hyponatremia associated with inappropriate secretion of antidiuretic hormone |
Other adverse effects | Increased appetite with weight gain (or occasional anorexia with weight loss) Sweating |