Table 2 Outcomes of acceptability, feasibility, and efficacy (non-randomized controlled trials)

Comer et al. (USA) [28]

CY-BOCS

24.2 (5.2) ^c

17.4 (5.9) ^c

Not Reported

2.54

Not Applicable

ADIS-IV-C/P

(OCD CSR)

6.2 (1.1) ^c

4.0 (1.4) ^c

Not Reported

5.88

Not Applicable

CGAS

51.8 ^d

58.6 ^d

Not Reported

2.87

Not Applicable

CGI-S

5.2 ^d

3.6 ^d

Not Reported

Not Reported

Not Applicable

CGI-I

Not Applicable

2.2 (0.8) ^c

Not Reported

Not Reported

Not Applicable

CSQ-8 (First Item)

Not Applicable

All mothers rated quality as “Excellent”

Not Applicable

Not Applicable

Not Applicable

Treatment dropout

Not Applicable

Dropout = 0

Not Applicable

Not Applicable

Not Applicable

Farrell et al. (Australia) [31]

CYBOCS

29.1 (4.2)

14.8 (7.7)

p< 0.001

2.09

11.8 (8.9) ^b

CY-BOCS-SR (Parent)

24.1(3.3)

12.9 (7.3)

p< 0.001

1.94

11.5 (9.5) ^b

ADIS-IV-C/P

(OCD CSR)

6.6 (0.5)

3.5 (2.0)

p< 0.001

2.28

3.3 (1.9) ^b

NIMH GOCS

10.7 (1.8)

6.3 (3.1)

p< 0.005

1.36

5.8 (3.6) ^b

CGI-S

5.6 (0.5)

3.1 (1.5)

p< 0.001

2.25

2.7 (1.6) ^b

CDI-S

13.6 (10.9)

10.3 (7.9)

p< 0.05

0.34

Not Reported

MASC

83.6 (35.0)

60.1 (26.1)

p= n.s.

0.76

Not Reported

PEDSQL

35.3 (12.1)

18.5 (14.9)

p< 0.05

1.23

Not Reported

Treatment dropout

Not Applicable

Dropout = 0

Not Applicable

Not Applicable

Not Applicable

Lenhard et al. (Sweden) [32]

CY-BOCS

21.3 (3.5)

12.1 (4.5)

p< 0.001

2.29

8.8 (5.1) ^a

9.1 (6.4) ^b

ChOCI –symptom

Parent

12.4 (6.8)

6.5 (5.1)

p< 0.001

0.94

5.3 (5.6) ^a

4.5 (4.3) ^b

ChOCI –impairment

Parent

24.9 (7.0)

17.8 (10.0)

p< 0.001

0.79

12.4 (8.1) ^a

11.5 (6.4) ^b

ChOCI –symptom

child

13.6 (8.7)

6.4 (6.6)

p< 0.001

0.92

5.3 (6.7) ^a

5.0 (6.6) ^b

ChOCI – impairment

child

22.6 (8.1)

11.6 (6.3)

p< 0.001

1.51

9.9 (8.9) ^a

10.4 (9.1) ^b

COIS-R Parent

25.3 (16.1)

16.8 (17.2)

p< 0.05

0.45

13.0 (15.7) ^a

13.9 (15.0) ^b

COIS-R Child

17.3 (15.5)

6.6 (7.9)

p< 0.001

0.88

5.2 (8.4) ^a

6.0 (9.0) ^b

CGI-I

Not Applicable

52% “Much Improved” or “Very Much Improved”

Not Applicable

Not Applicable

71 % “Much Improved” or “Very Much Improved” ^{a b}

CGAS

56.1 (6.3)

71.5 (9.3)

p< 0.001

-1.94

74.0 (9.0) ^a

73.5 (9.7) ^b

CDI-S

9.6 (1.4)

9.9 (1.2)

p= n.s.

-0.19

2.5 (2.7) ^a

2.2 (2.1) ^b

FAS

14.6 (8.4)

9.6 (7.1)

p<0.05

0.60

6.9 (8.1) ^a

6.5 (6.9) ^b

SDQ

Parent

12.0 (6.7)

10.3 (6.3)

p= n.s.

0.29

10.3 (6.6) ^a

9.7 (6.4) ^b

SDQ

child

13.5 (5.5)

10.6 (4.0)

p= n.s.

0.61

10.7 (4.2) ^a

10.5 (4.8) ^b

SCAS without OCD

Parent

25.2 (15.7)

16.0 (13.5)

p<0.001

0.63

16.4 (12.2) ^a

15.7 (14.1) ^b

SCAS OCD

Child

9.1 (5.0)

4.1 (3.4)

p<0.001

1.17

2.9 (3.8) ^a

3.3 (4.0) ^b

SCAS without OCD

Child

30.4 (16.9)

20.2 (13.5)

p<0.001

0.67

18.9 (14.0) ^a

18.3 (14.2) ^b

Not Applicable

Not Applicable

Not Applicable

Not Applicable

Not Applicable

Not Applicable

Treatment dropout

Not Applicable

8.3/12 Chapters completed by patients (3.0)

Not Applicable

Not Applicable

Not Applicable

4.7/5 Chapters completed by parents (0.8)