Skip to main content

Table 4 Summary estimates of diagnostic test accuracy by field strategy, by index test grader, by pupil status and by setting

From: Systematic review and meta-analysis of diagnostic accuracy of detection of any level of diabetic retinopathy using digital retinal imaging

Imaging strategy Index grader Non-mydriatic Mydriatic
Sensitivity Specificity Sensitivity Specificity
Estimate
(95% CI)
Number of studies Estimate
(95% CI)
Number of studies Estimate
(95% CI)
Number of studies Estimate
(95% CI)
Number of studies
Overall estimates   86%
(85–87%)
18 93%
(92–93%)
18 86%
(85–87%)
17 90%
(89–90%)
17
By index test grader Ophthalmologist 82%
(80–84%)
7 94%
(94–95%)
7 87%
(85–89%)
9 93%
(92–94%)
9
Retinologist 90%
(89–92%)
7 94%
(93–95%)
7 69%
(62–75%)
2 93%
(91–96%)
2
Retinal reader 89%
(86–93%)
3 91%
(88–94%)
3 86%
(84–88%)
4 92%
(91–94%)
4
SpR registrar 78%
(75–81%)
1 81%
(79–82%)
1 86%
(84–89%)
2 70%
(68–72%)
2
By field strategy 1F Ophthalmologist 73%
(69–77%)
3 96%
(94–97%)
3 78%
(75–81%)
4 94%
(92–95%)
4
Retinologist 79%
(75–84%)
3 81%
(76–86%)
3 69%
(62–75%)
2 93%
(91–96%)
2
Retinal reader 83%
(77–87%)
1 91%
(88–94%)
1 86%
(81–89%)
1 91%
(88–93%)
1
SpR registrar 78%
(75–81%)
1 81%
(79–82%)
1 No data No data
2F Ophthalmologist 87%
(84–90%)
2 90%
(88–92%)
  86%
(83–89%)
2 86%
(84–88%)
2
Retinologist 93%
(91–95%)
2 96%
(94–97%)
2 No data   No data  
Retinal reader No data No data 82%
(78–85%)
2 95%
(92–97%)
2
SpR registrar No data No data 86%
(84–89%)
2 70%
(68–72%)
2
> 2F Ophthalmologist 84%
(79–88%)
2 97% (95–98%) 2 93%
(91–96%)
3 96%
(94–98%)
2
Retinologist 82%
(75–90%)
2 86% (8–90%) 2 No data No data
Retinal reader 93%
(89–96%)
2 No data 90%
(86–93%)
1 90%
(87–92%)
1
SpR registrar No data No data No data No data
By setting Primary 85%
(83–86%)
8 92% (91–92%) 8 82%
(80–84%)
6 91%
(90–92%)
6
Other (secondary or tertiary) 90%
(88–91%)
10 95% (94–96%) 10 87%
(86–89%)
11 89%
(88–90%)
11