Table 3

Step

Search terms

1

exp medical record/or interview/or telephone interview/or survey?.mp. or questionnaire?.mp. or data system?.mp. or epidemiologic method?.mp. or incidence.tw. or mortality.tw. or cardiovascular mortality/or cancer mortality/or *mortality/or health episode statistics.mp. or electronic health record?.mp. or electronic patient record?.mp. or computeri?ed record-linkage system?.mp. or national registr*.mp. or national database*.mp. or routine data.mp. or routinely collected data.mp.

2

(cost effective* or cost benefit* or costs).mp. or clinical effectiveness/or effectiveness.mp. or survivors.mp. or hospital admission?.mp. or hospital episode?.mp. or hospitali?ation?.mp. or primary outcome*.mp. or secondary outcome*.mp. or outcome measure*.mp. or outcome assessment.mp. or outcomes research.mp. or treatment outcome/or treatment duration/

3

randomized controlled trial/or ((random* or blind* or placebo*).tw. and major clinical study/)

4

(Post-trial or posttrial or attrition or drop out? or dropout? or follow-up or followup? or extension* or trial closure? or long-term or longterm or extended observation*).mp.

5

1 and 2 and 3 and 4

6

(exp animals/or nonhuman/) not human/

7

5 not 6

8

limit 7 to (english language and yr=“2000 -Current”)

9

(letter or editorial or conference*).pt.

10

8 not 9