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Table 2 Characteristics of the included systematic reviews

From: Chinese herbal medicine for the treatment of primary hypertension: a methodology overview of systematic reviews

Researchers and publication time Types of included studies Number of studies (total sample) Age Interventions Follow-up time Evaluation criteria of methodology Conclusions
Treatment group Control group
Chen 2014 [11] RCT 12 (1001) 39–80 Banxia baizhu tianma tang + conventional medicine Conventional medicine Jadad As compared with conventional medicine banxia baizhu tianma tang combined with it can improve the clinical curative effect in treating high blood pressure
Wang 2012 [12] RCT 11 (981) 36–86 Danshen injection + control group Hemostatic agents、dehydrator, regulation of blood pressure, brain cell protective agent 6 months Jadad Danshen injection has a certain treatment effect in treating hypertensive cerebral hemorrhage, and the earlier the better
Guo 2013 [13] RCT 14 (1364) Liuwei dihuang pill + conventional medicine Conventional medicine Jadad The whole therapy effect of liuwei dihuang pill combined with conventional medicine is better than that of single conventional medicine, and so do the SBP and DBP
Zhou 2012 [22] RCT 8 (554) Tianma gouteng yin + captopril Captopril Jadad Compared with single captopril, the clinical efficacy of tianma gouteng yin combined with captopril is more better, which can improve symptoms with better blood pressure effect
Dong 2011 [23] RCT 6 (543) Tianma gouteng yin + captopril Captopril Jadad Tianma gouteng yin may obtain better treatment result and more security than enalapril in treatment of essential hypertension
Ren 2006 [24] RCT 11 (1010) TCM combination therapy including Chinese herb medicine, Chinese patent medicines, acupuncture, etc.) + conventional medicine Conventional medicine Jadad Traditional Chinese medicine may have similar effect with conventional medicine in primary hypertension therapy
Dai 2010 [25] RCT 9 (655) Therapied by Chinese herb medicine or combined with conventional medicine Conventional medicine Jadad Traditional Chinese medicine can reduce the SBP and DBP effectively, improve efficiency, integrated Chinese and Western treatment is more better
Du 2014 [26] RCT 10 (1777) Yangxue qingnao granules + conventional medicine Conventional medicine Risk of bias Yangxue qingnao granules can significantly improve headache, dizziness, insomnia symptoms of high blood pressure
Li 2012 [27] RCT 17 (1323) TCM combination therapy including Chinese herb medicine compound, Chinese patent medicines, acupuncture, etc.) + conventional medicine Conventional medicine Jadad Traditional Chinese medicine has a certain effect in treatment of elderly hypertension patients and reduced pulse pressure with symptoms reduced
Xiong 2012 [28] RCT 16 (1424) 19–78 Banxia baizhu tianma tang + blood pressure drugs Blood pressure drugs or placebo Risk of bias Banxia baizhu tianma tang has better antihypertensive effect
Wang 2013 [29] RCT 22 (1808) 30–74 Tianma gouteng yin + blood pressure drugs Blood pressure drugs Risk of bias The efficacy and safety evidence of tianma gouteng yin, as an adjunct of blood pressure medicine, needs further study
Wu 2013 [30] RCT 9 (784) Tianma gouteng yin Conventional medicine Jadad Tianma gouteng yin can effectively lower the SBP and DBP
  1. “–”means do not report related information