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Table 1 Data extraction elements

From: Anti-IgE monoclonal antibody therapy for the treatment of chronic rhinosinusitis: a systematic review

General data extraction elements
 • Study number
 • First author
 • Publication year
 • Country
 • Funding source
 • Study design
 • Polyp staging score used
 • Inclusion criteria
 • Exclusion criteria
 • Subjects (total (n), men (n), women (n))
 • Age (mean, median, range)
 • Number excluded
 • Study duration
Data extraction elements for the treatment (anti-IgE) and placebo arms
 • Subjects (total n, subjects with sinusitis and polyps (n), subjects with sinusitis without polyps (n), men (n), women (n), % subjects with asthma, % subjects with history of immunotherapy, subjects with allergy (n, %), number of dropouts/withdrawals from study)
 • Age (mean, median, range)
 • BMI (mean, median, range)
 • Disease severity
 • Concurrent medications
 • Comorbid conditions
 • Dosing regimen, dose amount, duration, frequency
 • Pre-CT score ± SD, post-CT score ± SD, length of follow-up, sample size
 • Pre-clinical polyp score ± SD, post-clinical polyp score ± SD, length of follow-up, sample size
 • Pre-quality of life instrument (SF-36, AQLQ, RSOM-31, TNSS, SNOT-20) ± SD, post-quality of life instrument (SF-36, AQLQ, RSOM-31, TNSS, SNOT-20) ± SD, length of follow-up, sample size
 • Pre-cellular inflammation (eosinophil count) ± SD, post-cellular inflammation (eosinophil count) ± SD, length of follow-up, sample size
 • Pre-nasal airflow (PNIF) ± SD, post-nasal airflow (PNIF) ± SD, length of follow-up, sample size
 • Pre-olfaction (UPSIT) ± SD, post-olfaction (UPSIT) ± SD, length of follow-up, sample size
 • Pre-systemic IgE levels ± SD, post-systemic IgE levels ± SD, length of follow-up, sample size
 • Pre-spirometric result ± SD, post-spirometric result ± SD, length of follow-up, sample size
 • List of adverse events
  1. PNIF peak nasal inspiratory flow, SF-36 36-Item Short Form Health Survey, AQLQ Asthma Quality of Life Questionnaire, RSOM-31 Rhinosinusitis Outcome Measure 31, TNSS Total Nasal Symptom Severity, SNOT-20 Sinonasal Outcome Test 20, UPSIT University of Pennsylvania Smell Identification Test