Table 1 Examples of treatment success of gastrointestinal disorders

Dyspepsia

Improvement in dyspepsia clinical scores, such as a dyspepsia score [25, 26], the Global Overall Severity score [27]

Peptic ulcer

• Complete healing of the ulcer as observed from endoscopy [28]; or

• Presence of negative tests for Helicobacter pylori 4 weeks or longer after the end of therapy [29]

IBS

Improvement in IBS clinical scores, such as:

• IBS-related symptom score [30]

• Functional Bowel Disorder Severity Index [31]

• IBS Severity Scoring System [32]

IBD - Crohn’s disease

Improvement in the Crohn's Disease Activity Index [33]

IBD - ulcerative colitis

Improvement in the clinical scores, such as Mayo Clinic Score [34], Modified Mayo Disease Activity Index [35]

GERD

Improvement in clinical scores, such as GERD score [36], Gastroesophageal Reflux Disease Activity Index [37]

GERD, gastroesophageal reflux disease; IBD, inflammatory bowel disease; IBS, irritable bowel disease.