Table 2 Study eligibility criteria

Inclusion criteria

• Prospective study, retrospective cohort study or randomized controlled trials

• Acute setting

• At least 80% of patients suffering from an acute TRAUMATIC brain lesion

• At least 80% of adults patients (≥18 years old)

• Data on red blood cell transfusion reported

Exclusion criteria

• Sample of patients with congenital hereditary blood disorders (example: sickle cell disease, β-thalassemia)

• Sample of patients with coagulation disorders (example: hemophilia, thrombotic thrombocytopenic purpura, Von Willebrand disease)