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Table 1 Codebook

From: The diagnostic accuracy of the Patient Health Questionnaire-2 (PHQ-2), Patient Health Questionnaire-8 (PHQ-8), and Patient Health Questionnaire-9 (PHQ-9) for detecting major depression: protocol for a systematic review and individual patient data meta-analyses

Variable

Description

Values/labels

STUDY_ID

This variable identifies the database that the data come from, using the primary author or principal investigator of the original study as the label

1 = Study 1

2 = Study 2

3 = Study 3

4 ….

COUNTRY

Country where the study took place

 

CLINICAL SETTING

Clinical setting where the study took place

1 = Primary care

2 = Specialty care

3 = Non-medical setting

DEPRESSD_PT_ID

DEPRESSD Registry ID.

Sequential numbers from 1 to n

AGE

Patient’s age

Numerical value

SEX

Patient’s sex

1 = Female

2 = Male

999 = Missing

PHQ9_Q1

Patient data for the first PHQ-9 item: Interest/pleasure

0 = Not at all

1 = Several days

2 = More than half the days

3 = Nearly every day

999 = Missing

PHQ9_Q2

Patient data for the second PHQ-9 item: Down/depressed/hopeless

0 = Not at all

1 = Several days

2 = More than half the days

3 = Nearly every day

999 = Missing

PHQ9_Q3

Patient data for the third PHQ-9 item: Sleep

0 = Not at all

1 = Several days

2 = More than half the days

3 = Nearly every day

999 = Missing

PHQ9_Q4

Patient data for the fourth PHQ-9 item: Tired/energy

0 = Not at all

1 = Several days

2 = More than half the days

3 = Nearly every day

999 = Missing

PHQ9_Q5

Patient data for the fifth PHQ-9 item: Appetite

0 = Not at all

1 = Several days

2 = More than half the days

3 = Nearly every day

999 = Missing

PHQ9_Q6

Patient data for the sixth PHQ-9 item: Feeling bad about self

0 = Not at all

1 = Several days

2 = More than half the days

3 = Nearly every day

999 = Missing

PHQ9_Q7

Patient data for the seventh PHQ-9 item: Concentrating

0 = Not at all

1 = Several days

2 = More than half the days

3 = Nearly every day

999 = Missing

PHQ9_Q8

Patient data for the eighth PHQ-9 item: Moving

0 = Not at all

1 = Several days

2 = More than half the days

3 = Nearly every day

999 = Missing

PHQ9_Q9

Patient data for the ninth PHQ-9 item: Deaths/hurting self

0 = Not at all

1 = Several days

2 = More than half the days

3 = Nearly every day

999 = Missing

PHQ9_Q10

Patient data for final PHQ-9 question: how difficult these problems have made life

0 = Not difficult at all

1 = Somewhat difficult

2 = Very difficult

3 = Extremely difficult

999 = Missing

PHQ9_TOTAL

Total PHQ-9 score (sum of the nine-item scores)

999 = Missing

DEP_CRITERION

Name of diagnostic interview

1 = SCID-IV

2 = CIDI

3 = DIS

4 = SCAN

5 = MINI

CLASSIF_SYSTEM

Classification system used to classify patients as depressed or not. Include version of DSM/ICD

1 = ICD-10

2 = DSM-IV

3 = DSM-III

MDD_DICHOT

Major depression diagnostic status

0 = no MDD

1 = MDD

999 = missing

CUR_PSYC_TX

Currently receiving psychological treatment for depression versus not currently receiving psychological treatment for depression

0 = Not currently receiving psychological treatment for depression

1 = Currently receiving psychological treatment for depression

777 = Unknown

999 = Missing

CUR_PHAR_TX

Currently receiving antidepressant medication versus not currently receiving antidepressant medication

0 = Not currently receiving antidepressant medication

1 = Currently receiving antidepressant medication

777 = Unknown

999 = Missing

CUR_UNSPEC_TX

Currently receiving treatment for depression or not currently receiving treatment for depression (type of treatment not specified)

0 = Not currently receiving unspecified treatment for depression

1 = Currently receiving unspecified treatment for depression

777 = Unknown

999 = Missing

ANY_CUR_TX

Currently receiving any kind of treatment (psychological, pharmacological, or unspecified) for depression or not currently receiving any kind of treatment for depression.

0 = Not currently receiving treatment for depression

1 = Currently receiving treatment for depression

777 = Unknown

999 = Missing

MEDICAL_COMORBIDITY

Primary medical comorbidity or multiple comorbidities

0 = None

1 = CVD

2 = Diabetes

3 = Cancer

4 = Rheumatic disease

5 = Substance abuse

6 = Other

7 = Multiple

RISK_OF_BIAS_PT_SEL

QUADAS-2: Risk of Bias: Patient Selection

1 = Low

2 = Unclear

3 = High

RISK_OF_BIAS_INDEX

QUADAS-2: Risk of Bias: Index Test

1 = Low

2 = Unclear

3 = High

RISK_OF_BIAS_REF_STD

QUADAS-2: Risk of Bias: Reference Standard

1 = Low

2 = Unclear

3 = High

RISK_OF_BIAS_FLOW

QUADAS-2: Risk of Bias: Flow and Timing

1 = Low

2 = Unclear

3 = High

APPLIC_PT_SEL

QUADAS-2: Applicability Concerns: Patient Selection

1 = Low

2 = Unclear

3 = High

APPLIC_INDEX

QUADAS-2: Applicability Concerns: Index Test

1 = Low

2 = Unclear

3 = High

APPLIC_REF_STD

QUADAS-2: Applicability Concerns: Reference Standard

1 = Low

2 = Unclear

3 = High