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Table 1 Review eligibility criteria
From: A protocol for a systematic review for perioperative pregabalin use
| Study characteristic | Inclusion criteria | Exclusion criteria |
|---|---|---|
| Patient population | · Adults undergoing elective surgical procedures | · Non-surgical use, such as anti-epileptic, chronic pain, psychiatric conditions, generalized anxiety disorder |
| · Trauma, burns without surgery | ||
| · Other painful medical conditions, such as diabetic peripheral neuropathy, post herpetic neuralgia, fibromyalgia | ||
| Intervention- Treatment | · Oral pregabalin (any dose) administered before and/or after surgery with or without background multimodal analgesia | · Gabapentin |
| · Studies of pregabalin in combination with another drug will also be included but excluded in sensitivity analyses | ||
| Intervention- Comparison | · Placebo or any specific analgesic (including pregabalin in a different dose or gabapentin) with any route of administration, except sedatives and hypnotics (for example, acetaminophen, nonsteroidal anti-inflammatory drugs, opioids, tricyclic antidepressants) | |
| · Comparators may or may not have been added on to background multimodal analgesia. | ||
| Study design | · Randomized controlled trials | · Case studies |
| · Observational studies | ||
| · Retrospective study | ||
| · Non-randomized | ||
| · Non controlled | ||
| · Expert opinion | ||
| Setting | · Inpatient with or without extension to outpatient settings | · Exclusively outpatient |
| Timing | · 48 to 24 hours before surgery to 7 days (for acute pain) and up to 6 months postsurgery (for chronic postoperative pain) |
