Table 1 Search strategy

#1

Patient report

(“self report*”[tiab] OR “self-report*”[tiab] OR Self Report[Mesh] OR “patient report*”[tiab] OR “patient-report*”[tiab] OR "Patient Reported Outcome Measures"[Mesh])

284,423

#2

Symptom

(symptom*[tiab] OR "Signs and Symptoms"[Mesh:NoExp])

1,463,218

#3

PNP

(psychoneurophys*[tiab] OR depression[tiab] OR depressive[tiab] OR “chronic fatigue”[tiab] OR anxiety[tiab] OR “panic disorder*”[tiab] OR “panic attack*”[tiab] OR phobia*[tiab] OR “phobic disorder*”[tiab] OR “chronic pain*”[tiab] OR “cognitive impair*”[tiab] OR “cognitive dysfunction*”[tiab] OR “cognitive decline*”[tiab] OR “brain fog*”[tiab] OR “chemo brain”[tiab] OR “mental fatigue”[tiab] OR dementia*[tiab] OR “sleep impairment*”[tiab] OR Insomnia[tiab] OR insomniac*[tiab] OR “poor sleep”[tiab] OR “sleep wake disorder*”[tiab] OR “sleep disorder*”[tiab] OR parasomnia*[tiab] OR “early waking”[tiab] OR “early awakening”[tiab] OR sleeplessness[tiab] OR dyssomnia*[tiab] OR hypersomnia*[tiab] OR “circadian rhythm disorder*”[tiab] OR parasomnia*[tiab] OR “sleep-related movement disorder*”[tiab] OR “sleep related movement disorder*”[tiab] OR “sleep movement disorder*”[tiab] OR “sleep-related rhythmic movement disorder*”[tiab] OR “restless leg*”[tiab] OR “sleep related breathing disorder*”[tiab] OR “sleep-related breathing disorder*”[tiab] OR “sleep apnea*”[tiab] OR “sleep disordered breathing”[tiab] OR “mood impairment*”[tiab] OR “psychotic affective disorder*”[tiab] OR “mood disorder*”[tiab] OR “negative affect*”[tiab] OR “poor self-concept”[tiab] OR “emotional distress*”[tiab] OR tension[tiab] OR tense[tiab] OR anger[tiab] OR angry[tiab] OR “emotional labilit*”[tiab] OR “rapid mood change*”[tiab] OR irritabilit*[tiab] OR irritable[tiab] OR “shortness of breath”[tiab] OR dyspnea*[tiab] OR "Irritable Mood"[Majr] OR "Dyspnea"[Majr] OR "Anger"[Majr] OR "Affective Disorders, Psychotic"[Majr] OR "Sleep Apnea Syndromes"[Majr] OR "Restless Legs Syndrome"[Majr] OR "Sleep Initiation and Maintenance Disorders"[Majr] OR "Sleep Wake Disorders"[Majr] OR "Parasomnias"[Majr] OR Dyssomnias[Majr] OR "Sleep Disorders, Intrinsic"[Majr] OR "Dementia"[Majr] OR "Mental Fatigue"[Majr:NoExp] OR "Cognitive Dysfunction"[Majr] OR "Phobic Disorders"[Majr] OR "Panic Disorder"[Majr] OR "Fatigue Syndrome, Chronic"[Majr] OR "Anxiety"[Majr] OR "Anxiety Disorders"[Majr:NoExp] OR "Depression"[Majr] OR "Depressive Disorder"[Majr])

1,355,318

#4

Chronic disease

(“chronic disease*”[tiab] OR “cardiovascular disease*”[tiab] OR “Ischemic heart disease*”[tiab] OR “heart attack*”[tiab] OR “myocardial infarction*”[tiab] OR angina[tiab] OR anginas[tiab] OR “coronary artery disease*”[tiab] OR “chronic heart failure”[tiab] OR arrythmia*[tiab] OR “peripheral vascular disease*”[tiab] OR aneurysm*[tiab] OR stroke[tiab] OR strokes[tiab] OR “cerebrovascular accident*”[tiab] OR “brain vascular accident*”[tiab] OR “brain infarct*”[tiab] OR “respiratory disease*”[tiab] OR COPD[tiab] OR “chronic obstructive pulmonary disease*”[tiab] OR “chronic obstructive airway disease*”[tiab] OR “chronic airflow obstruction*”[tiab] OR “chronic bronchitis”[tiab] OR emphysema*[tiab] OR “interstitial pulmonary fibros*”[tiab] OR asthma[tiab] OR asthmas[tiab] OR cancer[tiab] OR cancers[tiab] OR neoplasm*[tiab] OR malignan*[tiab] OR neoplasia*[tiab] OR diabetes[tiab] OR "Cardiovascular Diseases"[Majr:NoExp] OR "Heart Diseases"[Majr:NoExp] OR "Arrhythmias, Cardiac"[Majr:NoExp] OR "Heart Failure"[Majr:NoExp] OR "Myocardial Ischemia"[Majr:NoExp] OR "Angina Pectoris"[Majr:NoExp] OR "Coronary Disease"[Majr:NoExp] OR "Myocardial Infarction"[Majr:NoExp] OR "Peripheral Vascular Diseases"[Majr:NoExp] OR "Aneurysm"[Majr:NoExp] OR "Stroke"[Majr:NoExp] OR "Asthma"[Majr:NoExp] OR "Bronchitis, Chronic"[Majr:NoExp] OR "Pulmonary Disease, Chronic Obstructive"[Majr:NoExp] OR "Emphysema"[Majr:NoExp] OR "Pulmonary Emphysema"[Majr:NoExp] OR "Pulmonary Fibrosis"[Majr:NoExp] OR "Neoplasms"[Majr:NoExp] OR "Diabetes Mellitus"[Majr:NoExp] OR "Diabetes Mellitus, Type 1"[Majr] OR "Diabetes Mellitus, Type 2"[Majr])

5,231,424

#5

#1 AND #2 AND #3 AND #4

4948

#6

#5 AND English[lang]

4912

#7

#6 NOT (letter[ptyp] OR editorial[ptyp] OR comment[ptyp] OR news[ptyp] OR editorial[tiab] OR commentary[tiab] OR "Published Erratum"[Publication Type] OR errata[tiab] OR erratum[tiab] OR corrigenda[tiab] OR corrigendum[tiab] OR protocol[ti] OR protocols[ti] OR “meta-analysis”[tiab] OR “meta-analyses”[tiab] OR metanalyses[tiab] OR metanalysis[tiab] OR metaanalyses[tiab] OR metaanalysis[tiab] OR “meta analyses”[tiab] OR “meta analysis”[tiab] OR "Review"[Publication Type] OR “systematic review*”[tiab] OR "Systematic Review"[Publication Type] OR "Meta-Analysis" [Publication Type] OR "Network Meta-Analysis"[Mesh] OR “integrative review”[tiab])

4506