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Table 1 Inclusion/exclusion criteria

From: Contribution of environmental determinants to the risk of developing type 2 diabetes mellitus in a life-course perspective: a systematic review protocol

Evidence characteristics/Level of triage

Inclusion

Exclusion

Justification

At level 1 (first screening or title and abstract screening)/level 2 (selection based on full text or full-text screening)

Language

The study is published in English or possibly in French

The study is published in a language other than English or French

Data collection will be extended to French language publications to contribute to address possible publication bias. But this systematic review project does not have the resources to translate into languages other than English or French

Year of publication

The study is published before 2024

The study is published after 31 December 2023

An increasing body of research recognises the involvement of environmental determinants in the risk of developing type 2 diabetes (T2D). This situation illustrates the global awareness of the need to promote neighbourhoods conducive to healthy living behaviours to achieve complete well-being

Sources of evidence

- The study was published in a peer-reviewed journal

- The study was published in one of the grey literature sources of the Laval University Libraries

Public interest reports or magazines or popular magazines are to be excluded

Although peer review is an essential safeguard of the scientific process, in this research, it is recognised that grey literature sources are a means of addressing potential publication bias

Study design

The study may be experimental or non-experimental (cross-sectional, cohorts/longitudinal, case–control) or quasi-experimental (cohorts/longitudinal, case–control), with the aim to explain and quantify the relationship between T2DM (Outcome) and environmental determinants (exposure) using one risk estimator such as Risk ratio (RR), hazard ratio (HR) or odds ratio (OR)

The study uses a qualitative or mixed observational survey methodology

Qualitative data do not quantify the contribution of environmental determinants or objectively compare studies with each other

Exposure(s)

The study analyses the correlation, contribution or influence or impact of exposure to local food landscape or built environment or deprivation or rural or urban cultural norms of organization and use of space

The study does not address the contribution, influence, or impact of exposure to environmental determinants

This is an indispensable aspect of answering the research question

Comparator(s)

Evidence from control groups made up of individuals who may or may not be predisposed to the risk of T2DM or who are not permanently exposed to an unhealthy environment during their life course (men versus women, urban population vs rural population, unhealthy lifestyle behaviours and obese vs normal weight individuals) will be taken into account

Absence of comparator(s)

Subgroups may be used to improve knowledge of the nature of the relationship observed in this systematic review

Main outcome(s)

The study seeks to explain the risk of type 2 diabetes mellitus (causal or correlational)

The study does not seek to explain the risk of type 2 diabetes mellitus

This is an indispensable aspect of answering the research question. Risk was chosen for two reasons: firstly, this systematic review is more concerned with explanatory analyses; secondly, according to exploratory research, it is the most widely used statistical measure of association in studies in this field

Participants

Diabetic and nondiabetic individuals 18 years of age or older

Individuals under the age of 18 are included in the study population

Dysfunction in insulin production often appears in adulthood. It is therefore recognized that for environmental characteristics to have an impact on lifestyle behaviors, one must have been exposed to them in the life course at least until adulthood

Measure(s) of intervention, exposure

At least one indicator of rural or urban perception of organization and use of space or local food landscape or built environment or deprivation is being defined

There is no definition of environmental indicators

This is an indispensable aspect of answering the research question

Measure(s) outcome

At least one indicator of type 2 diabetes (prevalence, incidence for descriptive analyses and risk ratio (RR), hazard ratio (HR), or odds ratio (OR) for explanatory analyses) is being defined (using fasting blood glucose level or FBG and 2-h plasma glucose level or 2hPG level; glycated haemoglobin level or HbA1c; insulin and homoeostatic model assessment of insulin resistance level or HOMA-IR or simply based on administrative health data (for example, the codes E110 to E119 in the 10th revision of International Statistical Classification of Diseases and Related Health Problems or ICD-10) or self-reported cases validated by a concordance study published)

The studied measure of association between DMT2 and the environment is not a risk estimator

Type 2 diabetics account for 90–95% of Mellitus diabetes cases worldwide. This is an indispensable aspect of answering the research question. Risk was chosen for two reasons: First, the systematic review is more concerned with explanatory analyses of DMT2; second, based on exploratory research, it is the most widely used statistical measure of association in studies in this field of research