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Table 1 Definitions of key variables included in review

From: Impact of body size, nutrition and socioeconomic position in early life on the epigenome: a systematic review protocol

Term

Description

Epigenetics

Any recognised indicator of DNA methylation or histone modification, measured in any tissue

Body size

Any measure of body size including: weight, height, BMI, head circumference and growth (or change) in any of these measurements at birth and in early life

Nutrition

Any measure of maternal nutrition, supplement use and/or diet during pregnancy, breastfeeding/formula, weaning practices and nutrition/diet of the child in early life measured using dietary questionnaires and/or objectively measured nutritional biomarkers

Socioeconomic position (SEP)

Any recognised indicator of SEP within society, including occupation, education, income, occupational or social class, poverty and household overcrowding, as defined in reference [16], measured during early life