Publication characteristics | 100 Cochrane reviews (100 %) | 100 non-Cochrane reviews (100 %) | P value* |
---|---|---|---|
Intervention | |||
Pharmacologic | 55 (55 %) | 29 (29 %) | 0.020 |
Non-pharmacologic | 45 (45 %) | 71 (71 %) | 0.061 |
Review has ≥1 meta-analysis | |||
Yes | 85 (85 %) | 45 (45 %) | 0.0065 |
Included trials | |||
Number of randomized clinical trials in total | 1242 | 1249 | |
-Lowa risk of bias | 74 (6 %) | 25 of 424e (6 %) | 1.00 |
-Unclearb risk of bias | 407 (33 %) | 226 of 424e (53 %) | 0.0001 |
-Highc risk of bias | 761 (61 %) | 173 of 424e (41 %) | 0.0001 |
Reviews with ≥1 low risk of bias trial and ≥1 high risk of bias trial | 26 (26 %) | 6 of 18f (33 %) | 0.60 |
Reviews with ≥1 low risk of bias trial and ≥1 high or unclear risk of bias trial | 32 (32 %) | 8 of 18f (44 %) | 0.47 |
Number of randomized clinical trials includedd in a review | |||
-One to five | 39 (39 %) | 38 (38 %) | 1.00 |
-Six to ten | 23 (23 %) | 26 (26 %) | 0.75 |
->Ten | 38 (38 %) | 36 (36 %) | 0.89 |