Individual patient data meta-analysis of trials investigating the effectiveness of intra-articular glucocorticoid injections in patients with knee or hip osteoarthritis: an OA Trial Bank protocol for a systematic review

Table 1 Sources of risk of bias

	Item^a	Judgment
A) Sequence generation
	1. Was the method of randomization adequate?	Yes / No / Unsure
B) Allocation concealment
	2. Was the treatment allocation concealed?	Yes / No / Unsure
C) Was knowledge of the allocated interventions adequately prevented during the study?
	3. Was the patient blinded to the intervention?	Yes / No / Unsure
	4. Was the care provider blinded to the intervention?	Yes / No / Unsure
	5. Was the outcome assessor blinded to the intervention?	Yes / No / Unsure
D) Incomplete outcome data
	6. Were incomplete outcome data adequately addressed?
	E) Other sources of potential bias
	7. Were all randomized participants analyzed in the group to which they were allocated?	Yes / No / Unsure
	8. Were the groups similar at baseline regarding the most important prognostic indicators?	Yes / No / Unsure
	9. Were co-interventions avoided or similar?	Yes / No / Unsure
	10. Was the compliance acceptable in all groups?	Yes / No / Unsure
	11. Was the timing of the outcome assessment similar in all groups?	Yes / No / Unsure

^aCriteria for a judgment of ‘yes’ for the sources of risk of bias: see Additional file 1: Appendix 2.

ISSN: 2046-4053