Table 2 Review outcomes
From: A protocol for a systematic review for perioperative pregabalin use
Type of outcome | Outcome |
|---|---|
Primary perioperative efficacy outcomes | · Pain relief at rest and on movement (any measure) |
|  | · Reduction in postoperative opioid and other analgesic consumption (dose, frequency, and time of first use of rescue analgesia) |
Secondary perioperative and long-term outcomes | · Postoperative nausea and vomiting |
|  | · Anxiolysis |
|  | · Sleep restoration |
|  | · Early ambulation |
|  | · Early feeding |
|  | · Length of hospital stay |
|  | · Chronic postoperative pain |
Perioperative harms outcomes | · Somnolence |
|  | · Sedation |
|  | · Visual disturbances |
|  | · Confusion |
|  | · Respiratory depression |
|  | · Cognitive dysfunction |
|  | · Withdrawal due to adverse events |
|  | · Participants with at least one serious adverse event (as defined by the FDA) |
|  | · Mortality |
|  | · Participants with at least one adverse event |
|  | · Withdrawal due to lack of pregabalin efficacy |
FDA: Food and Drugs Administration | |