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  1. Liver resection is commonly performed for malignant and benign disease and is associated with frequent use of intraoperative and postoperative blood transfusions. Blood transfusions are potentially life-saving...

    Authors: Sean Bennett, Laura Baker, Risa Shorr, Guillaume Martel and Dean Fergusson

    Citation: Systematic Reviews 2016 5:38

    Content type: Protocol

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  2. Health information has become readily accessible through mass media, and people are playing a more active and autonomous role in their health. Much of the health information that was previously only available ...

    Authors: Leila Cusack, Chris B. Del Mar, Iain Chalmers and Tammy C. Hoffmann

    Citation: Systematic Reviews 2016 5:37

    Content type: Protocol

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  3. A peer-reviewed journal would not survive without the generous time and insightful comments of the reviewers, whose efforts often go unrecognized. Although final decisions are always editorial, they are greatl...

    Authors: David Moher, Paul Shekelle and Lesley A. Stewart

    Citation: Systematic Reviews 2016 5:36

    Content type: Reviewer acknowledgement

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  4. The spread of early detection and the improvement of cancer treatment have led to an increased prevalence of cancer survivors, including in the working age population. Return-to-work (RTW) of cancer survivors ...

    Authors: Régine Kiasuwa Mbengi, Renée Otter, Katrien Mortelmans, Marc Arbyn, Herman Van Oyen, Catherine Bouland and Christophe de Brouwer

    Citation: Systematic Reviews 2016 5:35

    Content type: Research

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  5. Some sedatives used in children and adolescents can affect memory function. Memory impairment of traumatic experience can minimize the chance of future psychological trauma. Knowledge about the potential of di...

    Authors: Karolline A. Viana, Anelise Daher, Lucianne C. Maia, Paulo S. Costa, Carolina C. Martins, Saul M. Paiva and Luciane R. Costa

    Citation: Systematic Reviews 2016 5:34

    Content type: Protocol

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  6. This letter describes a simple way of using Adobe Acrobat Pro DC to help select and auto-extract data from Portable Document Format (PDFs) of randomised trials in order to assist swift early selection of trial...

    Authors: Selin Nur, Clive E. Adams and David F. Brailsford

    Citation: Systematic Reviews 2016 5:33

    Content type: Letter

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  7. Physical performance such as muscle strength or walking speed of patients with coronary artery disease (CAD) is lower than that of people who do not have CAD and is related to mortality and re-admission rates....

    Authors: Shuhei Yamamoto, Takayoshi Yamaga, Yasunari Sakai, Takaaki Ishida, Saki Nakasone, Masayoshi Ohira, Erika Ota and Rintaro Mori

    Citation: Systematic Reviews 2016 5:32

    Content type: Protocol

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  8. In the UK, over 6500 people die by suicide each year. In England alone, this is one person every 2 h. Professionals assess risk of suicide in face-to-face contacts with people potentially at risk. The National...

    Authors: Rose McCabe, Ruth Garside, Amy Backhouse and Penny Xanthopoulou

    Citation: Systematic Reviews 2016 5:31

    Content type: Protocol

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  9. Despite progress in developing technologies for health promotion and disease treatment, mental disorders remain highly prevalent. In light of the associated personal and societal burden, primary prevention of ...

    Authors: Lasse Sander, Leonie Rausch and Harald Baumeister

    Citation: Systematic Reviews 2016 5:30

    Content type: Protocol

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    The Erratum to this article has been published in Systematic Reviews 2016 5:156

  10. Macular oedema (MO) describes the accumulation of fluid in the central part of the retina, known as the ‘macula’ which provides central vision. MO is the leading cause of sight loss in patients with intraocula...

    Authors: Mohammad O. Tallouzi, David J. Moore, Melanie Calvert, Philip I. Murray, Nicholas Bucknall and Alastair K. Denniston

    Citation: Systematic Reviews 2016 5:29

    Content type: Protocol

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  11. The need for systematic methods for reviewing evidence is continuously increasing. Evidence mapping is one emerging method. There are no authoritative recommendations for what constitutes an evidence map or wh...

    Authors: Isomi M. Miake-Lye, Susanne Hempel, Roberta Shanman and Paul G. Shekelle

    Citation: Systematic Reviews 2016 5:28

    Content type: Research

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  12. Bibliographic databases are the primary resource for identifying systematic reviews of health care interventions. Reliable retrieval of systematic reviews depends on the scope of indexing used by database prov...

    Authors: John Rathbone, Matt Carter, Tammy Hoffmann and Paul Glasziou

    Citation: Systematic Reviews 2016 5:27

    Content type: Research

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  14. Eczema is a common chronic or chronically relapsing, inflammatory skin disease that exerts a substantial negative impact on quality of life (QoL). The Harmonising Outcome Measures for Eczema (HOME) initiative ...

    Authors: Daniel Heinl, Cecilia A. C. Prinsen, Aaron M. Drucker, Robert Ofenloch, Rosemary Humphreys, Tracey Sach, Carsten Flohr and Christian Apfelbacher

    Citation: Systematic Reviews 2016 5:25

    Content type: Protocol

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  15. The length of postnatal hospital stay has declined over the last 40 years. There is little evidence to support a policy of early discharge following birth, and there is some concern about whether early dischar...

    Authors: Eleanor Jones, Beck Taylor, Christine MacArthur, Ruth Pritchett and Carole Cummins

    Citation: Systematic Reviews 2016 5:24

    Content type: Protocol

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  16. Of the over 1 million reported cases of traumatic brain injuries reported annually in the USA, a sizeable proportion are characterized as mild. Although it is generally well-accepted that most people who suffe...

    Authors: Chris Lepage, Tina Yuan, Stephanie Leon, Shawn Marshall, Patrick Labelle and Mark Ferland

    Citation: Systematic Reviews 2016 5:23

    Content type: Protocol

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  17. Most orthodontic treatment plans need some form of anchorage to control the reciprocal forces of tooth movement. Orthodontic mini implants (OMIs) have been hailed for having revolutionized orthodontics, becaus...

    Authors: Reint Meursinge Reynders, Laura Ronchi, Luisa Ladu, Nicola Di Girolamo, Jan de Lange, Nia Roberts and Sharon Mickan

    Citation: Systematic Reviews 2016 5:22

    Content type: Protocol

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  18. The prevalence of paternal depression in the postnatal period is estimated to be approximately 10 %. Effective partner education during pregnancy has the possibility to prevent postnatal mental health problems...

    Authors: Maiko Suto, Kenji Takehara, Yumina Yamane and Erika Ota

    Citation: Systematic Reviews 2016 5:21

    Content type: Protocol

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  19. The lack of evidence of the role of workplaces as settings for behaviour change delivery and the failure to recognise and address the complexity of the work environment has been acknowledged. This systematic r...

    Authors: Sarah A. Smith, Amelia A. Lake, Carolyn Summerbell, Vera Araujo-Soares and Frances Hillier-Brown

    Citation: Systematic Reviews 2016 5:20

    Content type: Protocol

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  20. Prosthetic hip implants have many combinations of bearing surface materials, sizes, and fixation techniques, which can determine the quality of life of patients after primary total hip replacement (THR) and th...

    Authors: Elsa M. R. Marques, Rachel Humphriss, Nicky J. Welton, Julian P. T. Higgins, William Hollingworth, Jose A. Lopez-Lopez, Howard Thom, Linda P. Hunt, Ashley W. Blom and Andrew D. Beswick

    Citation: Systematic Reviews 2016 5:19

    Content type: Protocol

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  21. Steroids are often combined with local anesthetic (LA) and injected to reduce pain associated with various chronic non-cancer pain (CNCP) complaints. The biological rationale behind injection of a steroid solu...

    Authors: Harsha Shanthanna, Jason W. Busse, Lehana Thabane, James Paul, Rachel Couban, Harman Choudhary, Alka Kaushal, Erica Suzumura, Isabel Kim and Prathiba Harsha

    Citation: Systematic Reviews 2016 5:18

    Content type: Protocol

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  23. Periodontal disease is an inflammatory disease of the tissues supporting the teeth. Women who have periodontal disease while pregnant may be at risk of adverse pregnancy outcomes. Although the association betw...

    Authors: Sizzle F. Vanterpool, Kathleen Tomsin, Leticia Reyes, Luc J. Zimmermann, Boris W. Kramer and Jasper V. Been

    Citation: Systematic Reviews 2016 5:16

    Content type: Protocol

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  25. The association between low socioeconomic status (SES) and poor health is well documented in the existing literature. Nonetheless, evidence on the relationship between SES and gastrointestinal (GI) infections ...

    Authors: Tanith C. Rose, Natalie Adams, David C. Taylor-Robinson, Benjamin Barr, Jeremy Hawker, Sarah O’Brien, Mara Violato and Margaret Whitehead

    Citation: Systematic Reviews 2016 5:13

    Content type: Protocol

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  26. Elevated levels of risky alcohol consumption and alcohol-related harm have been reported for sportspeople and supporters compared to non-sporting populations. Limited systematic reviews have been conducted to ...

    Authors: Melanie Kingsland, John H. Wiggers, Khanrin P. Vashum, Rebecca K. Hodder and Luke Wolfenden

    Citation: Systematic Reviews 2016 5:12

    Content type: Research

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  27. Acute diarrhea and acute gastroenteritis (AD/AGE) are common among children in low- and middle-income countries (LMIC) and high-income countries (HIC). Supportive therapy including maintaining feeding, prevent...

    Authors: Ivan D. Florez, Reem Al-Khalifah, Javier M. Sierra, Claudia M. Granados, Juan J. Yepes-Nuñez, Carlos Cuello-Garcia, Giordano Perez-Gaxiola, Adriana M. Zea, Gilma N. Hernandez, Areti-Angeliki Veroniki, Gordon H. Guyatt and Lehana Thabane

    Citation: Systematic Reviews 2016 5:14

    Content type: Protocol

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  28. Systematic reviews seek to bring together research evidence to answer the question for the review. The reviewers usually wish to compare, contrast and, if appropriate, combine the findings of the existing rese...

    Authors: Mike Clarke and Paula R. Williamson

    Citation: Systematic Reviews 2016 5:11

    Content type: Commentary

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  30. Traumatic brain injury (TBI) is a devastating condition with significant long-term mortality and morbidity. Despite current need for objective indicators to guide initial decision-making, few reliable acute ph...

    Authors: Hourmazd Haghbayan, Amélie Boutin, Mathieu Laflamme, François Lauzier, Michèle Shemilt, Lynne Moore, Ryan Zarychanski, Dean Fergusson and Alexis F. Turgeon

    Citation: Systematic Reviews 2016 5:10

    Content type: Protocol

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  32. Overweight and obesity in children and adults is a major public health concern. Emerging evidence suggests dietary sodium intake may be associated with obesity. This systematic review and meta-analysis will ai...

    Authors: Carley A. Grimes, Dieuwerke P. Bolhuis, Feng J. He and Caryl A. Nowson

    Citation: Systematic Reviews 2016 5:7

    Content type: Protocol

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  33. Cost-effectiveness analysis has been recognized as an important tool to determine the efficiency of healthcare interventions and services. There is a need for evaluating the reporting of methods and results of...

    Authors: Ferrán Catalá-López, Manuel Ridao, Adolfo Alonso-Arroyo, Anna García-Altés, Chris Cameron, Diana González-Bermejo, Rafael Aleixandre-Benavent, Enrique Bernal-Delgado, Salvador Peiró, Rafael Tabarés-Seisdedos and Brian Hutton

    Citation: Systematic Reviews 2016 5:6

    Content type: Research

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  34. Worldwide, the prevalences of diabetes and dementia are both increasing, particularly in older people. Rates of diabetes in people with dementia are between 13 and 20 %. Diabetes management and diabetic self-c...

    Authors: Frances Bunn, Claire Goodman, Jo Rycroft Malone, Peter Reece Jones, Chris Burton, Greta Rait, Daksha Trivedi, Antony Bayer and Alan Sinclair

    Citation: Systematic Reviews 2016 5:5

    Content type: Protocol

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  35. Overviews of systematic reviews attempt to systematically retrieve and summarise the results of multiple systematic reviews into a single document. Methods for conducting, interpreting and reporting overviews ...

    Authors: Carole Lunny, Sue E. Brennan, Steve McDonald and Joanne E. McKenzie

    Citation: Systematic Reviews 2016 5:4

    Content type: Protocol

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  37. Chronic kidney disease-mineral and bone disorders (CKD-MBD) have been associated with poor health outcomes, including diminished quality and length of life. Standard management for CKD-MBD includes phosphate-r...

    Authors: Nigar Sekercioglu, Jason W. Busse, Reem A. Mustafa, Gordon H. Guyatt and Lehana Thabane

    Citation: Systematic Reviews 2016 5:2

    Content type: Protocol

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  39. Research with a focus on Aboriginal and Torres Strait Islander Australian’s (hereafter referred to as Indigenous1) needs is crucial to ensure culturally appropriate evidence-based strategies are developed to impr...

    Authors: Sara Farnbach, Anne-Marie Eades and Maree Lisa Hackett

    Citation: Systematic Reviews 2015 4:189

    Content type: Protocol

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  40. Up to 90 % of people with scleroderma have gastrointestinal (GI) problems such as constipation, bloating, diarrhea, and malabsorption. These problems significantly impair quality of life. Our objective was to ...

    Authors: Brian Younho Hong, Raymond Giang, Lawrence Mbuagbaw, Maggie Larche and Lehana Thabane

    Citation: Systematic Reviews 2015 4:188

    Content type: Research

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  41. Suicidal behaviour is a complex phenomenon with a multitude of risk factors. Brain-derived neurotrophic factor (BDNF), a protein crucial to nervous system function, may be involved in suicide risk. The objecti...

    Authors: Rebecca B. Eisen, Stefan Perera, Laura Banfield, Rebecca Anglin, Luciano Minuzzi and Zainab Samaan

    Citation: Systematic Reviews 2015 4:187

    Content type: Research

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  42. The mental health of children and adolescents is a key area of health concern internationally. Previous empirical studies suggest that resilience may act as a protective mechanism towards the development of me...

    Authors: Julia Dray, Jenny Bowman, Luke Wolfenden, Elizabeth Campbell, Megan Freund, Rebecca Hodder and John Wiggers

    Citation: Systematic Reviews 2015 4:186

    Content type: Protocol

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  43. The long-term management of chronic diseases requires adoption of complex dietary recommendations, which can be facilitated by regular coaching to support sustained behaviour change. Telehealth interventions c...

    Authors: Jaimon T. Kelly, Dianne P. Reidlinger, Tammy C. Hoffmann and Katrina L. Campbell

    Citation: Systematic Reviews 2015 4:185

    Content type: Protocol

    Published on:

  44. Tobacco and alcohol are recognised as the major risk factors for both oral cavity (mouth) and oropharyngeal (throat) cancers, with increasing acceptance of the role of human papillomavirus (HPV) in the aetiolo...

    Authors: Sweta Mathur, David I. Conway, Heather Worlledge-Andrew, Lorna M.D. Macpherson and Alastair J. Ross

    Citation: Systematic Reviews 2015 4:184

    Content type: Protocol

    Published on:

  46. Testicular cancer is primarily treated with the surgical removal of the affected testis. About 50 % of testicular cancer patients present with a stage I seminoma. If no chemo- or radiotherapy as adjuvant treat...

    Authors: Frank Kunath, Annabel Spek, Katrin Jensen, Friedemann Zengerling and Stefanie Schmidt

    Citation: Systematic Reviews 2015 4:182

    Content type: Protocol

    Published on:

  49. Improving health-care outcomes for people living with dementia when they are admitted to hospital is a policy priority. Dementia friendly interventions in health care promote inclusion of patients and carers i...

    Authors: Melanie Handley, Frances Bunn and Claire Goodman

    Citation: Systematic Reviews 2015 4:180

    Content type: Protocol

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  50. Whilst nutrition is vital to survival in health, the precise role of nutrition during critical illness is controversial. More specifically, the exact amount of energy that is required during critical illness t...

    Authors: Emma J. Ridley, Andrew R. Davies, Carol Hodgson, Adam Deane, Michael Bailey and D. James Cooper

    Citation: Systematic Reviews 2015 4:179

    Content type: Protocol

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