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  1. Lung cancer (LC) is the most common cause of cancer death in the world and associated with significant economic burden. We conducted a review of published literature to identify prognostic factors associated w...

    Authors: Ruth Lewis, Maggie Hendry, Nafees Din, Marian A. Stanciu, Sadia Nafees, Annie Hendry, Zhi Hao Teoh, Thomas Lloyd, Rachel Parsonage, Richard D. Neal, Gareth Collier and Dyfed W. Huws
    Citation: Systematic Reviews 2019 8:171
  2. Psychiatric disorders are highly prevalent and associated with great symptomatic, functional, and health economic burdens. Psychotherapy is among the recommended and used interventions for most psychiatric dis...

    Authors: Sophie Juul, Stig Poulsen, Susanne Lunn, Per Sørensen, Janus Christian Jakobsen and Sebastian Simonsen
    Citation: Systematic Reviews 2019 8:169
  3. This systemic review aims to synthesise the current literature surrounding off-therapy surveillance imaging in children and young people with extra-cranial solid tumours, with a view to establishing if routine...

    Authors: Jessica E. Morgan, Melissa Harden and Robert S. Phillips
    Citation: Systematic Reviews 2019 8:168
  4. Depression is a common comorbidity in type 2 diabetes. Studies have consistently shown that major depression is associated with decreased diabetic self-care behaviour. People with subthreshold depression exper...

    Authors: Monika Shrestha, Amal Al-Ghareeb, Fatimah Alenazi and Richard Gray
    Citation: Systematic Reviews 2019 8:167
  5. Reporting standards in biomedical research have been shown to be suboptimal. The publication of the PRISMA statement has improved the completeness of reporting of systematic reviews, but several issues specifi...

    Authors: Trevor A. McGrath, David Moher and Matthew D. F. McInnes
    Citation: Systematic Reviews 2019 8:166
  6. Seriously ill children suffer from numerous symptoms at the end of their lives, including pain, anxiety, and restricted communication. There are currently no comprehensive overviews of which health interventio...

    Authors: Veerle E. Piette, Joachim Cohen, Luc Deliens, Nele Pauwels, Jutte van der Werff ten Bosch and Kim Beernaert
    Citation: Systematic Reviews 2019 8:165
  7. Physically aggressive behaviors are very common among older people living with cognitive impairment. These behaviors may have significant consequences for family and formal caregivers, as well as for the other...

    Authors: Anne Bourbonnais, Marie-Hélène Goulet, Philippe Landreville, Edith Ellefsen, Caroline Larue, Marie-Hélène Lalonde and Paul L. Gendreau
    Citation: Systematic Reviews 2019 8:164
  8. Early diagnosis and treatment of tuberculosis (TB) have been shown to reduce the impact of TB illness particularly, among TB key populations such as people living with HIV/AIDS, prisoners, refugees, migrants, ...

    Authors: Desmond Kuupiel, Vitalis Bawontuo and Tivani P. Mashamba-Thompson
    Citation: Systematic Reviews 2019 8:162
  9. Sexual dysfunction refers to a chain of psychiatric, individual, and couple’s experiences that manifests itself as a dysfunction in sexual desire, sexual arousal, orgasm, and pain during intercourse. The aim o...

    Authors: Mojdeh Banaei, Maryam Azizi, Azam Moridi, Sareh Dashti, Asiyeh Pormehr Yabandeh and Nasibeh Roozbeh
    Citation: Systematic Reviews 2019 8:161
  10. Human immunodeficiency virus (HIV) infection and intimate partner violence (IPV) remain highly sensitive areas that have issues to do with stigmatization in many African countries. Despite the fact that there ...

    Authors: Felix Apiribu, Busisiwe Purity Ncama and Elizabeth Joseph-Shehu
    Citation: Systematic Reviews 2019 8:159
  11. Dementia is one of the greatest health and care priorities globally. Caring for persons with dementia is a challenge and often leads to negative psychological, physiological and financial consequences for info...

    Authors: Vimal Sriram, Crispin Jenkinson and Michele Peters
    Citation: Systematic Reviews 2019 8:158
  12. Trauma represents a major global health problem projected to increase in importance over the next decade. The majority of deaths occur in low- and middle-income countries (LMICs) where survival rates are lower...

    Authors: John Whitaker, Max Denning, Nollaig O’Donohoe, Dan Poenaru, Elena Guadagno, Andy Leather and Justine Davies
    Citation: Systematic Reviews 2019 8:157
  13. Following publication of the original article [1], the authors opted to revise Table 1. Below is the updated version of the table.

    Authors: Lisa Biernatzki, Silke Kuske, Jutta Genz, Michaela Ritschel, Astrid Stephan, Christina Bächle, Sigrid Droste, Sandra Grobosch, Nicole Ernstmann, Nadja Chernyak and Andrea Icks
    Citation: Systematic Reviews 2019 8:156

    The original article was published in Systematic Reviews 2018 7:27

  14. The World Health Organization estimates that 29% of under-five mortality could be prevented with existing vaccines. However, non-consistent attendance for immunization appointments remains a global challenge t...

    Authors: Zeleke Abebaw Mekonnen, Kassahun Alemu Gelaye, Martin C. Were, Kassahun Dessie Gashu and Binyam Chakilu Tilahun
    Citation: Systematic Reviews 2019 8:154
  15. Understanding the effects of gait speed on biomechanical variables is fundamental for a proper evaluation of alterations in gait, since pathological individuals tend to walk slower than healthy controls. There...

    Authors: Claudiane Arakaki Fukuchi, Reginaldo Kisho Fukuchi and Marcos Duarte
    Citation: Systematic Reviews 2019 8:153
  16. Much effort is made to ensure Cochrane reviews are based on reliably extracted data. There is a commitment to wide access to these data—for novel processing and/or reuse—but delivering this access is problematic.

    Authors: Lena Schmidt, Farhad Shokraneh, Kirsten Steinhausen and Clive E. Adams
    Citation: Systematic Reviews 2019 8:151
  17. Phase III randomised controlled trials aim not just to increase the sum of human knowledge, but also to improve treatment, care or prevention for future patients through changing policy and practice. To achiev...

    Authors: Annabelle South, Julia Bailey, Mahesh K. B. Parmar and Claire L. Vale
    Citation: Systematic Reviews 2019 8:150
  18. Asthma is a major worldwide public health problem affecting an estimated 334 million people with over 300,000 deaths annually. Twenty-two million disability-adjusted life years (DALYs) are lost annually due to...

    Authors: Pisirai Ndarukwa, Moses John Chimbari and Elopy N. Sibanda
    Citation: Systematic Reviews 2019 8:149
  19. Even though data suggest that palliative care (PC) improves patient quality of life, caregiver burden, cost, and intensive care unit (ICU) length of stay, integration of PC in the ICU is far from being univers...

    Authors: Victoria Metaxa, Despina Anagnostou, Savvas Vlachos, Nishkantha Arulkumaran, Ingeborg van Dusseldorp, Sherihane Bensemmane, Rebecca Aslakson, Judy E. Davidson, Rik Gerritsen, Christiane Hartog and Randall Curtis
    Citation: Systematic Reviews 2019 8:148
  20. Obesity is increasing globally. Chronic kidney disease (CKD) is strongly associated with obesity. Kidney function is commonly estimated with equations using creatinine (such as CKD-EPI equation) which is a pro...

    Authors: Sriram Sriperumbuduri, Robert Dent, Janine Malcolm, Swapnil Hiremath, Ran Klein, Christine A. White, Pierre Antoine Brown and Ayub Akbari
    Citation: Systematic Reviews 2019 8:147
  21. Ocular toxoplasmosis (OT) is the most common cause of posterior uveitis, leading to visual impairment in a high proportion of patients. Antibiotics and corticosteroids lower the risk of permanent visual impair...

    Authors: John E. Feliciano-Alfonso, Andrés Vargas-Villanueva, María Alejandra Marín, Laura Triviño, Natalia Carvajal, Manuela Moreno, Tatiana Luna, Clara Lopez de Mesa, Juliana Muñoz-Ortiz and Alejandra de-la-Torre
    Citation: Systematic Reviews 2019 8:146
  22. New software packages help to improve the efficiency of conducting a systematic review through automation of key steps in the systematic review. The aim of this study was to gather qualitative data on the usab...

    Authors: Gina Cleo, Anna Mae Scott, Farhana Islam, Blair Julien and Elaine Beller
    Citation: Systematic Reviews 2019 8:145
  23. There is some evidence that simply measuring physical activity alone can increase self-reported physical activity behaviour. Objective measures of physical activity in intervention studies have increased subst...

    Authors: Nicole Freene, Rachel Davey and Steven M. McPhail
    Citation: Systematic Reviews 2019 8:144
  24. Tendinopathies are specific degenerative conditions of the tendon characterized by pain and disability. The most common tendinopathies of the lower limbs are patellar, Achilles, gluteal, and proximal tendinopa...

    Authors: Yuri Rafael dos Santos Franco, Gisela Cristiane Miyamoto, Katherinne Ferro Moura Franco, Rodrigo Ribeiro de Oliveira and Cristina Maria Nunes Cabral
    Citation: Systematic Reviews 2019 8:142
  25. Autism spectrum disorder (ASD) is a complex developmental disorder characterised by impaired social interaction and communication, and restrictive and repetitive behaviour. Previous systematic reviews have tra...

    Authors: Ferrán Catalá-López, Manuel Ridao, Isabel Hurtado, Amparo Núñez-Beltrán, Ricard Gènova-Maleras, Adolfo Alonso-Arroyo, Aurelio Tobías, Rafael Aleixandre-Benavent, Miguel A. Catalá and Rafael Tabarés-Seisdedos
    Citation: Systematic Reviews 2019 8:141
  26. Acceptance and commitment therapy (ACT) can be effective in treating chronic pain. Despite evidence supporting the effectiveness of ACT, uncertainties remain regarding which subgroups in the chronic pain popul...

    Authors: Jiaxi Lin, Whitney Scott, Lewis Carpenter, Sam Norton, Matthias Domhardt, Harald Baumeister and Lance M. McCracken
    Citation: Systematic Reviews 2019 8:140
  27. Immuno-oncology, and in particular, check-point inhibitors (CPIs), have led to a paradigm shift in the field of cancer care. The cost of new drug development is high, and many novel agents in oncology are sign...

    Authors: Ying Wang, Pierre Camateros, Denise Smith, David Dawe and Peter Ellis
    Citation: Systematic Reviews 2019 8:139
  28. North America is in the midst of an unabated opioid overdose epidemic due to the increasing non-medical use of fentanyl and ultra-potent opioids. Naloxone is an effective antidote to opioid toxicity, yet its o...

    Authors: Lindsay Victoria Shaw, Jessica Moe, Roy Purssell, Jane A. Buxton, Jesse Godwin, Mary M. Doyle-Waters, Penelope M. A. Brasher, Jeffrey P. Hau, Jason Curran and Corinne M. Hohl
    Citation: Systematic Reviews 2019 8:138
  29. Shared decision-making is an approach to making treatment-based decisions that rely on the patient encounter and clear discussions between the patient and the healthcare provider. Patients with arthritis of th...

    Authors: Daniel L. Riddle, Trisha Sando, Talicia Tarver, James Slover, Robert A. Perera, Rafael Sierra, Juan P. Brito and Victor M. Montori
    Citation: Systematic Reviews 2019 8:137
  30. Despite the increased utilization of clinical pathways (CPWs) as a strategy to improve patient and system outcomes in hospitals, there remain ongoing challenges with their conceptualization, implementation, an...

    Authors: Adegboyega K. Lawal, Gary Groot, Donna Goodridge, Shannon Scott and Leigh Kinsman
    Citation: Systematic Reviews 2019 8:136
  31. Telemedicine use is increasing in many specialties, but its impact on clinical outcomes in infectious diseases has not been systematically studied and reviewed. The proposed systematic review will evaluate the...

    Authors: Jason P. Burnham, Stephanie A. Fritz, Lauren H. Yaeger and Graham A. Colditz
    Citation: Systematic Reviews 2019 8:135
  32. Living alone has become more common in today’s societies. Despite the high number of the population living alone, research directed towards the mental wellbeing issues related to living alone has been limited....

    Authors: Nina Tamminen, Tarja Kettunen, Tuija Martelin, Jaakko Reinikainen and Pia Solin
    Citation: Systematic Reviews 2019 8:134
  33. Cervical cancer is a major public health issue in the world, especially in developing countries. It can be prevented through vaccination against HPV (primary prevention) and through screening and treatment of ...

    Authors: Alex Baleka Mutombo, Cindy Simoens, Rahma Tozin, Johannes Bogers, Jean-Pierre Van Geertruyden and Yves Jacquemyn
    Citation: Systematic Reviews 2019 8:132
  34. Upon surviving the first year post-lung transplantation, recipients can expect a median survival of 8 years. Within the first year, graft failure and multi-organ failure (possibly secondary to graft failure) a...

    Authors: Farid Foroutan, Gordon Guyatt, Erik Friesen, Luis Enrique Colunga Lozano, Aman Sidhu and Maureen Meade
    Citation: Systematic Reviews 2019 8:131
  35. Consuming whey protein supplements, along with physiotherapy and psychotherapy, have been recognised in sports performance. Whey protein supplements (WPS) is one of the commonly used supplements as ergogenic a...

    Authors: Fui-Ching Lam, Tahir Mehmood Khan, Hani Faidah, Abdul Haseeb and Amer Hayat Khan
    Citation: Systematic Reviews 2019 8:130
  36. Estimation of the dietary requirements for vitamin D is crucial from a public health perspective in providing a framework for the prevention of vitamin D deficiency. It has been shown that pooling individual p...

    Authors: Kevin D. Cashman and Christian Ritz
    Citation: Systematic Reviews 2019 8:128
  37. Physical attractiveness or unattractiveness wields a tremendous impact on the social and psychological components of life. Many individuals with facial deformities are treated more negatively than normal indiv...

    Authors: Mikaela I. Poling and Craig R. Dufresne
    Citation: Systematic Reviews 2019 8:127
  38. Sensorineural hearing loss (SNHL) is the most common form of hearing impairment and is characterized by a loss of receptor hair cells and/or spiral ganglion neurons. Regenerative stem cell therapy could potent...

    Authors: Kevin T. Chorath, Matthew J. Willis, Nicolas Morton-Gonzaba, Walter J. Humann and Alvaro Moreira
    Citation: Systematic Reviews 2019 8:126
  39. There is great interest in the possibility that ‘stage of illness’ moderates treatment outcomes in bipolar disorder (BD). Much remains unknown about the construct of stage of illness, but there is evidence tha...

    Authors: Hailey Tremain, Kathryn Fletcher, Jan Scott, Carla McEnery, Michael Berk and Greg Murray
    Citation: Systematic Reviews 2019 8:125
  40. Many people who have common mental disorders, such as depression and anxiety, also have some psychotic experiences. These experiences are associated with higher clinical complexity, poor treatment response, an...

    Authors: Emma Soneson, Debra Russo, Clare Knight, Louise Lafortune, Margaret Heslin, Jan Stochl, Alex Georgiadis, Julieta Galante, Robbie Duschinsky, Nick Grey, Leticia Gonzalez-Blanco, Juliet Couche, Michelle Griffiths, Hannah Murray, Nesta Reeve, Joanne Hodgekins…
    Citation: Systematic Reviews 2019 8:124
  41. Better characterisation of the epidemiological data on respiratory viral infections among people with acute respiratory tract infection (ARTI) can help to implement efficient strategies to curb the burden of A...

    Authors: Sebastien Kenmoe, Jean Joel Bigna, Abdou Fatawou Modiyinji, Fredy Brice N. Simo and Richard Njouom
    Citation: Systematic Reviews 2019 8:122
  42. Hepatitis E virus (HEV) is one of the major causes of acute hepatitis in humans worldwide with a case-fatality rate of 1–4% in the general population that might reach 30% in pregnant women. In the past decade ...

    Authors: Abdou Fatawou Modiyinji, Jean Joel Bigna, Fredy Brice N. Simo, Moise Nola, Marie S. Ndangang, Sebastien Kenmoe and Richard Njouom
    Citation: Systematic Reviews 2019 8:120

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